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C4 Therapeutics, Inc.

CCCC
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001662579

No open-market purchases or sales by C4 Therapeutics, Inc. insiders were filed in the last 90 days; 147 institutions reported holding it in 13F filings for Q2 2026, worth $547.6M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in C4 Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
147
+24 vs. Q1 2026
Shares held
117.6M
+33.1M (+39.2%) vs. Q1 2026
Total value
$547.6M
+$326.3M (+147.5%) vs. Q1 2026
New holders
51
54 more added
Sold out
27
27 more reduced

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CCCC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 147 institutions
Q1 2021: 83 institutionsQ2 2021: 107 institutionsQ3 2021: 113 institutionsQ4 2021: 119 institutionsQ1 2022: 125 institutionsQ2 2022: 113 institutionsQ3 2022: 114 institutionsQ4 2022: 117 institutionsQ1 2023: 121 institutionsQ2 2023: 100 institutionsQ3 2023: 84 institutionsQ4 2023: 92 institutionsQ1 2024: 106 institutionsQ2 2024: 115 institutionsQ3 2024: 118 institutionsQ4 2024: 113 institutionsQ1 2025: 115 institutionsQ2 2025: 102 institutionsQ3 2025: 97 institutionsQ4 2025: 101 institutionsQ1 2026: 123 institutionsQ2 2026: 147 institutions
Value heldQ2 2026: $547.6M
Q1 2021: $926.8MQ2 2021: $1.21BQ3 2021: $1.54BQ4 2021: $1.15BQ1 2022: $904.8MQ2 2022: $297.2MQ3 2022: $345.9MQ4 2022: $231.4MQ1 2023: $117.5MQ2 2023: $94.1MQ3 2023: $64.5MQ4 2023: $265.6MQ1 2024: $475.6MQ2 2024: $281.3MQ3 2024: $365.9MQ4 2024: $231.8MQ1 2025: $102.6MQ2 2025: $78.2MQ3 2025: $116.6MQ4 2025: $152.5MQ1 2026: $221.3MQ2 2026: $547.6M
Institutions holding CCCC and their total value by quarter
QuarterHoldersValue
Q2 2026147$547.6M
Q1 2026123$221.3M
Q4 2025101$152.5M
Q3 202597$116.6M
Q2 2025102$78.2M
Q1 2025115$102.6M
Q4 2024113$231.8M
Q3 2024118$365.9M
Q2 2024115$281.3M
Q1 2024106$475.6M
Q4 202392$265.6M
Q3 202384$64.5M
Q2 2023100$94.1M
Q1 2023121$117.5M
Q4 2022117$231.4M
Q3 2022114$345.9M
Q2 2022113$297.2M
Q1 2022125$904.8M
Q4 2021119$1.15B
Q3 2021113$1.54B
Q2 2021107$1.21B
Q1 202183$926.8M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding C4 Therapeutics, Inc.; share changes are against Q1 2026.

Institutions holding CCCC in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Morgan Stanley8,867,338$41.4M0.00%−205,062−2.3%Reduced
Ra Capital Management, L.P.8,000,000$37.4M0.32%00.0%Unchanged
BlackRock, Inc.7,896,718$36.9M0.00%+5,848,192+285.5%Added
Lynx1 Capital Management LP7,326,691$34.2M3.95%+327,789+4.7%Added
Squadron Capital Management LLC7,200,000$33.6M11.51%+4,950,000+220.0%Added
Bain Capital Life Sciences Investors, LLC7,171,910$33.5M1.99%00.0%Unchanged
JPMorgan Chase & Co4,747,424$20.7M0.00%+1,524,370+47.3%Added
Vanguard Capital Management LLC4,417,731$20.6M0.00%+555,879+14.4%Added
Citadel Advisors LLC4,187,580$19.6M0.01%+1,676,565+66.8%Added
Goldman Sachs Group Inc3,530,991$16.5M0.00%+1,143,613+47.9%Added
Wasatch Advisors Inc3,522,644$16.5M0.11%+560,883+18.9%Added
Two Sigma Investments, LP3,469,707$16.2M0.01%+434,073+14.3%Added
Soleus Capital Management, L.P.3,377,981$15.8M0.54%−425,961−11.2%Reduced
Silverarc Capital Management, LLC3,032,060$14.2M1.58%+1,120,275+58.6%Added
Bank of America Corp2,656,359$12.4M0.00%+297,118+12.6%Added
Geode Capital Management, LLC2,522,163$11.8M0.00%+1,571,120+165.2%Added
Ikarian Capital, LLC2,433,000$11.4M1.86%+2,433,000New
State Street Corp2,115,621$9.88M0.00%+1,732,648+452.4%Added
Acadian Asset Management LLC1,806,199$8.43M0.01%−84,715−4.5%Reduced
Candriam Luxembourg S.C.A.1,796,937$8.38M0.04%+1,796,937New
D. E. Shaw & Co., Inc.1,740,989$8.13M0.01%+680,658+64.2%Added
Susquehanna International Group, LLP1,732,210$8.09M0.01%+445,370+34.6%Added
Patient Square Capital LP1,608,815$7.51M1.16%+1,608,815New
HighVista Strategies LLC1,348,136$6.30M1.44%+1,348,136New
Renaissance Technologies LLC1,189,828$5.56M0.01%−1,271,987−51.7%Reduced
Dimensional Fund Advisors LP1,188,507$5.55M0.00%+745,989+168.6%Added
Northern Trust Corp1,160,547$5.42M0.00%+971,068+512.5%Added
Congress Asset Management Co1,003,437$4.69M0.03%+172,813+20.8%Added
FMR LLC894,054$4.18M0.00%+621,686+228.3%Added
UBS Group AG828,970$3.87M0.00%+613,093+284.0%Added
Charles Schwab Investment Management Inc781,060$3.65M0.00%+328,832+72.7%Added
Boothbay Fund Management, LLC736,331$3.44M0.07%+736,331New
Vanguard Portfolio Management LLC680,094$3.18M0.00%+680,094New
Vanguard Fiduciary Trust Co609,146$2.84M0.00%+125,015+25.8%Added
ExodusPoint Capital Management, LP580,195$2.71M0.03%+532,688+1,121.3%Added
Velan Capital Investment Management LP570,000$2.66M1.63%+570,000New
StemPoint Capital LP523,648$2.45M0.42%+70,412+15.5%Added
Rockefeller Capital Management L.P.495,817$2.32M0.00%+495,817New
Nuveen, LLC484,010$2.26M0.00%+484,010New
Wells Fargo & Company452,701$2.11M0.00%−415,210−47.8%Reduced
Man Group plc408,648$1.91M0.00%+152,180+59.3%Added
Platinum Investment Management Ltd384,766$1.80M0.44%00.0%Unchanged
Seven Fleet Capital Management LP381,169$1.78M0.29%+324,093+567.8%Added
Qube Research & Technologies Ltd370,554$1.73M0.00%−381,560−50.7%Reduced
Atom Investors LP364,351$1.70M0.15%+228,304+167.8%Added
Susquehanna Portfolio Strategies, LLC335,079$1.56M0.02%+74,800+28.7%Added
Adage Capital Partners GP, L.L.C.325,000$1.52M0.00%+325,000New
Jane Street Group, LLC302,750$1.41M0.00%−944,146−75.7%Reduced
Connor, Clark & Lunn Investment Management Ltd.300,734$1.40M0.00%+23,551+8.5%Added
ADAR1 Capital Management, LLC291,957$1.36M0.06%+248,957+579.0%Added
Invesco Ltd.290,226$1.36M0.00%+45,719+18.7%Added
Panagora Asset Management Inc264,947$1.24M0.00%+178,187+205.4%Added
LPL Financial LLC253,165$1.18M0.00%+6,365+2.6%Added
Bank of New York Mellon Corp249,517$1.17M0.00%+249,517New
Wellington Management Group LLP227,768$1.06M0.00%+227,768New
Marshall Wace, LLP227,003$1.06M0.00%+71,508+46.0%Added
Millennium Management LLC215,386$1.01M0.00%−1,177,956−84.5%Reduced
Jump Financial, LLC182,700$853.2K0.01%+182,700New
Point72 Asset Management, L.P.173,965$812.4K0.00%+4,869+2.9%Added
Squarepoint Ops LLC170,834$797.8K0.00%+130,170+320.1%Added
Price T Rowe Associates Inc155,881$728.0K0.00%+84,335+117.9%Added
Headlands Technologies LLC153,972$719.0K0.08%+153,972New
American Century Companies Inc150,681$703.7K0.00%+65,237+76.4%Added
XTX Topco Ltd135,438$632.5K0.01%+88,287+187.2%Added
Palumbo Wealth Management LLC132,417$618.4K0.13%+132,417New
Rhumbline Advisers131,877$615.9K0.00%+129,161+4,755.6%Added
Bridgeway Capital Management, LLC131,100$612.2K0.01%00.0%Unchanged
Walleye Capital LLC115,125$537.6K0.00%−123,993−51.9%Reduced
Alps Advisors Inc112,214$524.0K0.00%+112,214New
Canada Pension Plan Investment Board101,500$474.0K0.00%−34,100−25.1%Reduced
Deutsche Bank AG98,873$461.7K0.00%+98,873New
Virtu Financial LLC98,094$458.0K0.01%+98,094New
Verition Fund Management LLC95,000$443.6K0.00%+95,000New
Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group85,000$396.9K0.10%00.0%Unchanged
Barclays PLC74,516$348.0K0.00%−243,361−76.6%Reduced
BNP Paribas Arbitrage, SA74,373$347.3K0.00%−115,975−60.9%Reduced
Crestwood Advisors Group LLC66,536$310.7K0.00%00.0%Unchanged
Intrepid Family Office LLC65,000$303.6K0.28%+5,000+8.3%Added
CV Advisors LLC65,000$303.6K0.06%+65,000New
MetLife Investment Management61,393$286.7K0.00%+61,393New
Jain Global LLC57,562$268.8K0.00%−4,828−7.7%Reduced
Thrivent Financial for Lutherans52,763$247.0K0.00%+52,763New
Citigroup Inc49,389$230.6K0.00%+6,961+16.4%Added
Mirae Asset Global ETFs Holdings Ltd.46,474$217.0K0.00%+46,474New
SEI Investments Co42,376$197.9K0.00%+17,242+68.6%Added
Quadrature Capital Ltd36,726$171.5K0.00%−26,034−41.5%Reduced
Alliancebernstein L.P.64,780$170.4K0.00%+64,780New
Caption Management, LLC35,000$163.4K0.01%+35,000New
Vanguard Global Advisers, LLC33,832$158.0K0.00%00.0%Unchanged
Dynamic Technology Lab Private Ltd32,828$153.0K0.03%+32,828New
Prudential Financial Inc31,235$145.9K0.00%+15,285+95.8%Added
Police & Firemen's Retirement System of New Jersey29,893$139.6K0.00%+29,893New
Manufacturers Life Insurance Company, The27,513$128.5K0.00%+27,513New
Jacobs Levy Equity Management, Inc25,111$117.3K0.00%−239,509−90.5%Reduced
Cresset Asset Management, LLC25,000$116.8K0.00%00.0%Unchanged
New York State Common Retirement Fund24,100$112.5K0.00%+24,100New
StoneX Group Inc.22,420$102.3K0.00%+22,420New
Group One Trading, L.P.21,773$101.7K0.00%+21,773New
Scientech Research LLC21,260$99.3K0.08%+21,260New
Quantbot Technologies LP20,827$97.3K0.00%+20,827New