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C4 Therapeutics, Inc.

CCCC
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001662579

No open-market purchases or sales by C4 Therapeutics, Inc. insiders were filed in the last 90 days; 147 institutions reported holding it in 13F filings for Q2 2026, worth $547.6M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in C4 Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
102
−13 vs. Q1 2025
Shares held
54.7M
−9.42M (−14.7%) vs. Q1 2025
Total value
$78.2M
−$24.4M (−23.8%) vs. Q1 2025
New holders
26
32 more added
Sold out
39
32 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CCCC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 102 institutions
Q1 2021: 83 institutionsQ2 2021: 107 institutionsQ3 2021: 113 institutionsQ4 2021: 119 institutionsQ1 2022: 125 institutionsQ2 2022: 113 institutionsQ3 2022: 114 institutionsQ4 2022: 117 institutionsQ1 2023: 121 institutionsQ2 2023: 100 institutionsQ3 2023: 84 institutionsQ4 2023: 92 institutionsQ1 2024: 106 institutionsQ2 2024: 115 institutionsQ3 2024: 118 institutionsQ4 2024: 113 institutionsQ1 2025: 115 institutionsQ2 2025: 102 institutionsQ3 2025: 97 institutionsQ4 2025: 101 institutionsQ1 2026: 123 institutionsQ2 2026: 147 institutions
Value heldQ2 2025: $78.2M
Q1 2021: $926.8MQ2 2021: $1.21BQ3 2021: $1.54BQ4 2021: $1.15BQ1 2022: $904.8MQ2 2022: $297.2MQ3 2022: $345.9MQ4 2022: $231.4MQ1 2023: $117.5MQ2 2023: $94.1MQ3 2023: $64.5MQ4 2023: $265.6MQ1 2024: $475.6MQ2 2024: $281.3MQ3 2024: $365.9MQ4 2024: $231.8MQ1 2025: $102.6MQ2 2025: $78.2MQ3 2025: $116.6MQ4 2025: $152.5MQ1 2026: $221.3MQ2 2026: $547.6M
Institutions holding CCCC and their total value by quarter
QuarterHoldersValue
Q2 2026147$547.6M
Q1 2026123$221.3M
Q4 2025101$152.5M
Q3 202597$116.6M
Q2 2025102$78.2M
Q1 2025115$102.6M
Q4 2024113$231.8M
Q3 2024118$365.9M
Q2 2024115$281.3M
Q1 2024106$475.6M
Q4 202392$265.6M
Q3 202384$64.5M
Q2 2023100$94.1M
Q1 2023121$117.5M
Q4 2022117$231.4M
Q3 2022114$345.9M
Q2 2022113$297.2M
Q1 2022125$904.8M
Q4 2021119$1.15B
Q3 2021113$1.54B
Q2 2021107$1.21B
Q1 202183$926.8M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding C4 Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding CCCC in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Wasatch Advisors Inc7,424,662$10.6M0.06%+700,253+10.4%Added
Lynx1 Capital Management LP7,098,133$10.2M2.93%00.0%Unchanged
Soleus Capital Management, L.P.6,978,942$9.98M0.69%00.0%Unchanged
OrbiMed Advisors LLC6,830,300$9.77M0.25%00.0%Unchanged
Morgan Stanley4,754,188$6.80M0.00%+708,859+17.5%Added
Vanguard Group Inc3,018,022$4.32M0.00%−352,858−10.5%Reduced
Bank of America Corp2,008,004$2.87M0.00%+17,180+0.9%Added
BlackRock, Inc.1,828,614$2.61M0.00%−3,455,799−65.4%Reduced
Bain Capital Life Sciences Investors, LLC1,111,910$1.59M0.20%00.0%Unchanged
Millennium Management LLC1,101,342$1.57M0.00%+1,035,445+1,571.3%Added
Renaissance Technologies LLC1,093,188$1.56M0.00%+878,688+409.6%Added
Tang Capital Management LLC900,000$1.29M0.07%00.0%Unchanged
Goldman Sachs Group Inc880,258$1.26M0.00%+257,538+41.4%Added
Two Sigma Advisers, LP811,400$1.16M0.00%+10,800+1.3%Added
Geode Capital Management, LLC745,053$1.07M0.00%−685,235−47.9%Reduced
Two Sigma Investments, LP683,599$977.5K0.00%+168,996+32.8%Added
UBS Group AG572,026$818.0K0.00%−300,744−34.5%Reduced
Jane Street Group, LLC492,612$704.4K0.00%+480,035+3,816.8%Added
Jacobs Levy Equity Management, Inc441,735$631.7K0.00%−255,918−36.7%Reduced
Dimensional Fund Advisors LP431,888$617.5K0.00%−82,267−16.0%Reduced
AQR Capital Management LLC383,789$548.8K0.00%+243,257+173.1%Added
Charles Schwab Investment Management Inc331,897$474.6K0.00%−142,946−30.1%Reduced
State Street Corp287,373$410.9K0.00%−937,045−76.5%Reduced
Cubist Systematic Strategies, LLC239,959$343.1K0.00%+239,959New
Royal Bank of Canada238,957$342.0K0.00%+233,392+4,193.9%Added
Hennion & Walsh Asset Management, Inc.208,766$298.5K0.01%−9,645−4.4%Reduced
BNP Paribas Arbitrage, SA206,177$294.8K0.00%+188,081+1,039.4%Added
ArrowMark Colorado Holdings LLC204,505$292.4K0.01%−1,082,207−84.1%Reduced
FMR LLC201,358$287.9K0.00%+7,608+3.9%Added
Adage Capital Partners GP, L.L.C.200,000$286.0K0.00%−1,350,000−87.1%Reduced
LPL Financial LLC196,255$280.6K0.00%+2,345+1.2%Added
Atom Investors LP190,182$272.0K0.02%−78,650−29.3%Reduced
Invesco Ltd.155,017$221.7K0.00%+15,531+11.1%Added
Squarepoint Ops LLC143,687$205.5K0.00%+143,687New
Susquehanna International Group, LLP141,056$201.7K0.00%+67,274+91.2%Added
Northern Trust Corp139,673$199.7K0.00%−360,095−72.1%Reduced
Acadian Asset Management LLC139,723$198.0K0.00%+112,048+404.9%Added
Jain Global LLC136,219$194.8K0.00%+112,016+462.8%Added
Mariner, LLC132,765$189.9K0.00%−47,607−26.4%Reduced
Susquehanna Portfolio Strategies, LLC126,900$181.5K0.00%+126,900New
XTX Topco Ltd108,278$154.8K0.01%+68,178+170.0%Added
Bridgeway Capital Management, LLC104,900$150.0K0.00%−25,000−19.2%Reduced
D. E. Shaw & Co., Inc.89,475$127.9K0.00%+10,200+12.9%Added
Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group85,000$121.5K0.08%00.0%Unchanged
Man Group plc78,487$112.2K0.00%−7,136−8.3%Reduced
Aster Capital Management (DIFC) Ltd77,734$111.2K0.03%+77,734New
HRT Financial LP71,106$101.0K0.00%+58,072+445.5%Added
Susquehanna Fundamental Investments, LLC67,617$96.7K0.00%−144,386−68.1%Reduced
Y-Intercept (Hong Kong) Ltd52,521$75.1K0.00%+52,521New
Barclays PLC45,823$65.5K0.00%−61,697−57.4%Reduced
Point72 Asia (Singapore) Pte. Ltd.43,447$62.1K0.01%+43,446+4,344,600.0%Added
Tower Research Capital LLC (TRC)40,592$58.0K0.00%+33,317+458.0%Added
Intrepid Family Office LLC40,000$57.2K0.06%00.0%Unchanged
R Squared Ltd30,587$43.7K0.02%+30,587New
Brookstone Capital Management29,325$41.9K0.00%+29,325New
Crestwood Advisors Group LLC29,000$41.5K0.00%+29,000New
Catalyst Funds Management Pty Ltd28,300$40.5K0.01%+28,300New
Farallon Capital Management, L.L.C.28,000$40.0K0.00%00.0%Unchanged
Cresset Asset Management, LLC25,000$35.8K0.00%−978−3.8%Reduced
HSBC Holdings PLC25,157$35.6K0.00%−330−1.3%Reduced
Virtu Financial LLC24,377$35.0K0.00%+24,377New
Bank of Montreal24,200$34.6K0.00%+3,400+16.3%Added
Citigroup Inc22,816$32.6K0.00%−20,579−47.4%Reduced
Dynamic Technology Lab Private Ltd21,476$31.0K0.00%+21,476New
Commonwealth Equity Services, LLC21,111$30.0K0.00%−4,989−19.1%Reduced
Ieq Capital, LLC18,822$26.9K0.00%+635+3.5%Added
Captrust Financial Advisors17,039$24.4K0.00%+637+3.9%Added
Ewa, LLC16,643$23.8K0.01%+16,643New
Hudson Bay Capital Management LP16,095$23.0K0.00%+16,095New
DRW Securities, LLC15,836$22.6K0.00%+15,836New
Ethic Inc.15,164$21.2K0.00%+15,164New
JustInvest LLC14,720$21.1K0.00%−4,875−24.9%Reduced
China Universal Asset Management Co., Ltd.14,261$20.4K0.00%+22+0.2%Added
Quadrature Capital Ltd13,547$19.3K0.00%−2,462−15.4%Reduced
CI Private Wealth, LLC12,695$18.2K0.00%−50−0.4%Reduced
Price T Rowe Associates Inc12,400$18.0K0.00%−25,743−67.5%Reduced
Gsa Capital Partners LLP10,963$16.0K0.00%−32,978−75.1%Reduced
US Bancorp11,000$15.7K0.00%−600−5.2%Reduced
National Asset Management, Inc.11,000$15.7K0.00%00.0%Unchanged
Two Sigma Securities, LLC10,589$15.1K0.00%+10,589New
CWM, LLC10,156$15.0K0.00%−4,273−29.6%Reduced
Engineers Gate Manager LP10,418$14.9K0.00%+10,418New
Abel Hall, LLC10,225$14.6K0.01%+10,225New
JPMorgan Chase & Co4,606$6.59K0.00%−29,813−86.6%Reduced
Point72 (DIFC) Ltd3,953$5.65K0.00%+3,953New
Mirae Asset Global Investments Co., Ltd.2,743$3.92K0.00%+368+15.5%Added
Rhumbline Advisers2,716$3.88K0.00%−86,917−97.0%Reduced
Clear Street Markets LLC2,122$3.03K0.00%+1,967+1,269.0%Added
GF Fund Management Co. Ltd.1,751$2.50K0.00%00.0%Unchanged
Wells Fargo & Company1,529$2.19K0.00%−522,090−99.7%Reduced
Advisor Group Holdings, Inc.1,500$2.15K0.00%+1,500New
Syntax Research, Inc.1,000$1.43K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC430$6150.00%+267+163.8%Added
Fortitude Family Office, LLC325$4650.00%+325New
EverSource Wealth Advisors, LLC310$4440.00%+277+839.4%Added
Skopos Labs, Inc.295$4220.00%+295New
SBI Securities Co., Ltd.150$2150.00%00.0%Unchanged
Raymond James Financial Inc135$1930.00%+135New
Essential Partners LLC133$1900.00%+133New
IFP Advisors, Inc34$480.00%+34New