C4 Therapeutics, Inc.
CCCC- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001662579
No open-market purchases or sales by C4 Therapeutics, Inc. insiders were filed in the last 90 days; 147 institutions reported holding it in 13F filings for Q2 2026, worth $547.6M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in C4 Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 97
- −5 vs. Q2 2025
- Shares held
- 52.5M
- −2.15M (−3.9%) vs. Q2 2025
- Total value
- $116.6M
- +$38.4M (+49.1%) vs. Q2 2025
- New holders
- 21
- 26 more added
- Sold out
- 26
- 38 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CCCC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 147 | $547.6M |
| Q1 2026 | 123 | $221.3M |
| Q4 2025 | 101 | $152.5M |
| Q3 2025 | 97 | $116.6M |
| Q2 2025 | 102 | $78.2M |
| Q1 2025 | 115 | $102.6M |
| Q4 2024 | 113 | $231.8M |
| Q3 2024 | 118 | $365.9M |
| Q2 2024 | 115 | $281.3M |
| Q1 2024 | 106 | $475.6M |
| Q4 2023 | 92 | $265.6M |
| Q3 2023 | 84 | $64.5M |
| Q2 2023 | 100 | $94.1M |
| Q1 2023 | 121 | $117.5M |
| Q4 2022 | 117 | $231.4M |
| Q3 2022 | 114 | $345.9M |
| Q2 2022 | 113 | $297.2M |
| Q1 2022 | 125 | $904.8M |
| Q4 2021 | 119 | $1.15B |
| Q3 2021 | 113 | $1.54B |
| Q2 2021 | 107 | $1.21B |
| Q1 2021 | 83 | $926.8M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding C4 Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Lynx1 Capital Management LP | 7,098,133 | $15.8M | 3.21% | 00.0% | Unchanged |
| Soleus Capital Management, L.P. | 7,053,942 | $15.7M | 0.84% | +75,000+1.1% | Added |
| OrbiMed Advisors LLC | 5,235,146 | $11.6M | 0.28% | −1,595,154−23.4% | Reduced |
| Morgan Stanley | 4,972,032 | $11.0M | 0.00% | +217,844+4.6% | Added |
| Wasatch Advisors Inc | 4,852,741 | $10.8M | 0.06% | −2,571,921−34.6% | Reduced |
| Vanguard Group Inc | 3,191,557 | $7.09M | 0.00% | +173,535+5.7% | Added |
| Bank of America Corp | 2,053,162 | $4.56M | 0.00% | +45,158+2.2% | Added |
| Millennium Management LLC | 1,934,225 | $4.29M | 0.00% | +832,883+75.6% | Added |
| Silverarc Capital Management, LLC | 1,897,383 | $4.21M | 0.61% | +1,897,383 | New |
| BlackRock, Inc. | 1,595,639 | $3.54M | 0.00% | −232,975−12.7% | Reduced |
| Bain Capital Life Sciences Investors, LLC | 1,111,910 | $2.47M | 0.16% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 936,950 | $2.08M | 0.00% | −156,238−14.3% | Reduced |
| Tang Capital Management LLC | 900,000 | $2.00M | 0.08% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 834,726 | $1.85M | 0.00% | +151,127+22.1% | Added |
| Two Sigma Advisers, LP | 763,100 | $1.69M | 0.00% | −48,300−6.0% | Reduced |
| Geode Capital Management, LLC | 725,304 | $1.61M | 0.00% | −19,749−2.7% | Reduced |
| Susquehanna International Group, LLP | 515,437 | $1.14M | 0.00% | +374,381+265.4% | Added |
| Jacobs Levy Equity Management, Inc | 503,145 | $1.12M | 0.00% | +61,410+13.9% | Added |
| Citadel Advisors LLC | 481,449 | $1.07M | 0.00% | +481,449 | New |
| Goldman Sachs Group Inc | 459,893 | $1.02M | 0.00% | −420,365−47.8% | Reduced |
| Shay Capital LLC | 420,000 | $932.4K | 0.17% | +420,000 | New |
| Charles Schwab Investment Management Inc | 350,606 | $778.3K | 0.00% | +18,709+5.6% | Added |
| Dimensional Fund Advisors LP | 349,289 | $775.5K | 0.00% | −82,599−19.1% | Reduced |
| State Street Corp | 287,373 | $638.0K | 0.00% | 00.0% | Unchanged |
| Susquehanna Portfolio Strategies, LLC | 272,053 | $604.0K | 0.01% | +145,153+114.4% | Added |
| FMR LLC | 211,348 | $469.2K | 0.00% | +9,990+5.0% | Added |
| Hennion & Walsh Asset Management, Inc. | 205,033 | $455.2K | 0.02% | −3,733−1.8% | Reduced |
| ArrowMark Colorado Holdings LLC | 204,505 | $454.0K | 0.01% | 00.0% | Unchanged |
| Jane Street Group, LLC | 203,568 | $451.9K | 0.00% | −289,044−58.7% | Reduced |
| LPL Financial LLC | 200,930 | $446.1K | 0.00% | +4,675+2.4% | Added |
| Invesco Ltd. | 191,820 | $425.8K | 0.00% | +36,803+23.7% | Added |
| Royal Bank of Canada | 182,640 | $405.0K | 0.00% | −56,317−23.6% | Reduced |
| XTX Topco Ltd | 149,962 | $332.9K | 0.02% | +41,684+38.5% | Added |
| Cubist Systematic Strategies, LLC | 138,657 | $307.8K | 0.00% | −101,302−42.2% | Reduced |
| Northern Trust Corp | 138,319 | $307.1K | 0.00% | −1,354−1.0% | Reduced |
| Mariner, LLC | 128,237 | $284.7K | 0.00% | −4,528−3.4% | Reduced |
| Acadian Asset Management LLC | 128,108 | $282.0K | 0.00% | −11,615−8.3% | Reduced |
| Qube Research & Technologies Ltd | 115,973 | $257.5K | 0.00% | +115,973 | New |
| Algert Global LLC | 106,300 | $236.0K | 0.00% | +106,300 | New |
| Marshall Wace, LLP | 106,275 | $235.9K | 0.00% | +106,275 | New |
| Man Group plc | 90,278 | $200.4K | 0.00% | +11,791+15.0% | Added |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | 85,000 | $188.7K | 0.11% | 00.0% | Unchanged |
| State of Wyoming | 82,509 | $183.2K | 0.02% | +82,509 | New |
| BNP Paribas Arbitrage, SA | 80,806 | $179.4K | 0.00% | −125,371−60.8% | Reduced |
| Bridgeway Capital Management, LLC | 79,900 | $177.4K | 0.00% | −25,000−23.8% | Reduced |
| Intrepid Family Office LLC | 70,000 | $155.4K | 0.14% | +30,000+75.0% | Added |
| Susquehanna Fundamental Investments, LLC | 67,617 | $150.1K | 0.01% | 00.0% | Unchanged |
| Crestwood Advisors Group LLC | 66,536 | $147.7K | 0.00% | +37,536+129.4% | Added |
| UBS Group AG | 61,650 | $136.9K | 0.00% | −510,376−89.2% | Reduced |
| Barclays PLC | 43,062 | $95.6K | 0.00% | −2,761−6.0% | Reduced |
| Catalyst Funds Management Pty Ltd | 42,500 | $94.3K | 0.01% | +14,200+50.2% | Added |
| Graham Capital Management, L.P. | 40,628 | $90.2K | 0.00% | +40,628 | New |
| Jefferies Financial Group Inc. | 38,200 | $84.8K | 0.00% | +38,200 | New |
| Voleon Capital Management LP | 28,420 | $63.1K | 0.00% | +28,420 | New |
| Farallon Capital Management, L.L.C. | 28,000 | $62.2K | 0.00% | 00.0% | Unchanged |
| Cresset Asset Management, LLC | 25,000 | $55.5K | 0.00% | 00.0% | Unchanged |
| American Century Companies Inc | 24,248 | $53.8K | 0.00% | +24,248 | New |
| CI Private Wealth, LLC | 22,702 | $50.4K | 0.00% | +10,007+78.8% | Added |
| Point72 Asia (Singapore) Pte. Ltd. | 21,708 | $48.2K | 0.01% | −21,739−50.0% | Reduced |
| Commonwealth Equity Services, LLC | 20,510 | $46.0K | 0.00% | −601−2.8% | Reduced |
| Ewa, LLC | 19,510 | $43.3K | 0.01% | +2,867+17.2% | Added |
| Caitong International Asset Management Co., Ltd | 19,146 | $42.5K | 0.03% | +19,146 | New |
| Wells Fargo & Company | 18,660 | $41.4K | 0.00% | +17,131+1,120.4% | Added |
| R Squared Ltd | 17,880 | $39.7K | 0.02% | −12,707−41.5% | Reduced |
| Engineers Gate Manager LP | 16,286 | $36.2K | 0.00% | +5,868+56.3% | Added |
| Captrust Financial Advisors | 14,889 | $33.1K | 0.00% | −2,150−12.6% | Reduced |
| JustInvest LLC | 14,574 | $32.4K | 0.00% | −146−1.0% | Reduced |
| Prudential Financial Inc | 14,300 | $31.7K | 0.00% | +14,300 | New |
| HSBC Holdings PLC | 13,629 | $30.1K | 0.00% | −11,528−45.8% | Reduced |
| Zacks Investment Management | 13,043 | $29.0K | 0.00% | +13,043 | New |
| Wolverine Trading, LLC | 12,710 | $28.3K | 0.00% | +12,710 | New |
| Price T Rowe Associates Inc | 12,400 | $28.0K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 12,475 | $27.7K | 0.00% | −1,786−12.5% | Reduced |
| Group One Trading, L.P. | 12,432 | $27.6K | 0.00% | +12,417+82,780.0% | Added |
| D. E. Shaw & Co., Inc. | 11,863 | $26.3K | 0.00% | −77,612−86.7% | Reduced |
| National Asset Management, Inc. | 11,000 | $24.4K | 0.00% | 00.0% | Unchanged |
| Ethic Inc. | 10,508 | $23.3K | 0.00% | −4,656−30.7% | Reduced |
| Simplicity Wealth,LLC | 10,213 | $22.7K | 0.00% | +10,213 | New |
| Abel Hall, LLC | 10,140 | $22.5K | 0.01% | −85−0.8% | Reduced |
| Squarepoint Ops LLC | 10,099 | $22.4K | 0.00% | −133,588−93.0% | Reduced |
| Tower Research Capital LLC (TRC) | 8,414 | $18.7K | 0.00% | −32,178−79.3% | Reduced |
| Simplex Trading, LLC | 7,836 | $17.0K | 0.00% | +7,836 | New |
| Advisor Group Holdings, Inc. | 4,530 | $11.3K | 0.00% | +3,030+202.0% | Added |
| JPMorgan Chase & Co | 4,429 | $9.83K | 0.00% | −177−3.8% | Reduced |
| Citigroup Inc | 3,264 | $7.25K | 0.00% | −19,552−85.7% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,751 | $6.11K | 0.00% | +8+0.3% | Added |
| Rhumbline Advisers | 2,716 | $6.03K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,463 | $3.25K | 0.00% | −288−16.4% | Reduced |
| JFS Wealth Advisors, LLC | 1,000 | $2.22K | 0.00% | +1,000 | New |
| Point72 (DIFC) Ltd | 234 | $519 | 0.00% | −3,719−94.1% | Reduced |
| Nisa Investment Advisors, LLC | 156 | $346 | 0.00% | −274−63.7% | Reduced |
| SBI Securities Co., Ltd. | 152 | $337 | 0.00% | +2+1.3% | Added |
| Wealthspire Advisors, LLC | 100 | $222 | 0.00% | +100 | New |
| Advisory Services Network, LLC | 74 | $164 | 0.00% | +74 | New |
| SRS Capital Advisors, Inc. | 55 | $122 | 0.00% | +55 | New |
| IFP Advisors, Inc | 17 | $38 | 0.00% | −17−50.0% | Reduced |
| CWM, LLC | 146 | $0 | 0.00% | −10,010−98.6% | Reduced |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −383,789−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −190,182−100.0% | Sold out |