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C4 Therapeutics, Inc.

CCCC
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001662579

No open-market purchases or sales by C4 Therapeutics, Inc. insiders were filed in the last 90 days; 147 institutions reported holding it in 13F filings for Q2 2026, worth $547.6M in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in C4 Therapeutics, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
125
+6 vs. Q4 2021
Shares held
37.3M
+1.43M (+4.0%) vs. Q4 2021
Total value
$904.8M
−$250.1M (−21.7%) vs. Q4 2021
New holders
29
47 more added
Sold out
23
32 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CCCC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 125 institutions
Q1 2021: 83 institutionsQ2 2021: 107 institutionsQ3 2021: 113 institutionsQ4 2021: 119 institutionsQ1 2022: 125 institutionsQ2 2022: 113 institutionsQ3 2022: 114 institutionsQ4 2022: 117 institutionsQ1 2023: 121 institutionsQ2 2023: 100 institutionsQ3 2023: 84 institutionsQ4 2023: 92 institutionsQ1 2024: 106 institutionsQ2 2024: 115 institutionsQ3 2024: 118 institutionsQ4 2024: 113 institutionsQ1 2025: 115 institutionsQ2 2025: 102 institutionsQ3 2025: 97 institutionsQ4 2025: 101 institutionsQ1 2026: 123 institutionsQ2 2026: 147 institutions
Value heldQ1 2022: $904.8M
Q1 2021: $926.8MQ2 2021: $1.21BQ3 2021: $1.54BQ4 2021: $1.15BQ1 2022: $904.8MQ2 2022: $297.2MQ3 2022: $345.9MQ4 2022: $231.4MQ1 2023: $117.5MQ2 2023: $94.1MQ3 2023: $64.5MQ4 2023: $265.6MQ1 2024: $475.6MQ2 2024: $281.3MQ3 2024: $365.9MQ4 2024: $231.8MQ1 2025: $102.6MQ2 2025: $78.2MQ3 2025: $116.6MQ4 2025: $152.5MQ1 2026: $221.3MQ2 2026: $547.6M
Institutions holding CCCC and their total value by quarter
QuarterHoldersValue
Q2 2026147$547.6M
Q1 2026123$221.3M
Q4 2025101$152.5M
Q3 202597$116.6M
Q2 2025102$78.2M
Q1 2025115$102.6M
Q4 2024113$231.8M
Q3 2024118$365.9M
Q2 2024115$281.3M
Q1 2024106$475.6M
Q4 202392$265.6M
Q3 202384$64.5M
Q2 2023100$94.1M
Q1 2023121$117.5M
Q4 2022117$231.4M
Q3 2022114$345.9M
Q2 2022113$297.2M
Q1 2022125$904.8M
Q4 2021119$1.15B
Q3 2021113$1.54B
Q2 2021107$1.21B
Q1 202183$926.8M

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding C4 Therapeutics, Inc.; share changes are against Q4 2021.

Institutions holding CCCC in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
RTW Investments, LP4,531,982$109.9M2.28%+2,037,017+81.6%Added
Price T Rowe Associates Inc4,377,372$106.2M0.01%+292,574+7.2%Added
BlackRock Inc.3,139,990$76.2M0.00%−265,992−7.8%Reduced
State Street Corp2,227,759$54.0M0.00%+638,006+40.1%Added
Perceptive Advisors LLC2,082,723$50.5M1.05%−126,190−5.7%Reduced
Vanguard Group Inc2,022,142$49.1M0.00%+5,683+0.3%Added
ArrowMark Colorado Holdings LLC1,909,023$46.3M0.41%+134,519+7.6%Added
Bain Capital Life Sciences Investors, LLC1,642,210$39.8M3.87%00.0%Unchanged
Wasatch Advisors Inc1,538,525$37.3M0.18%+243,063+18.8%Added
Pictet Asset Management SA1,131,441$27.4M0.03%+70,813+6.7%Added
Janus Henderson Group PLC1,086,782$26.4M0.01%+40,837+3.9%Added
Millennium Management LLC990,941$24.0M0.03%+237,550+31.5%Added
Geode Capital Management, LLC667,819$16.2M0.00%−18,357−2.7%Reduced
Morgan Stanley657,572$16.0M0.00%−260,898−28.4%Reduced
Pura Vida Investments, LLC624,860$15.2M1.83%+595,616+2,036.7%Added
FMR LLC599,281$14.5M0.00%−49,700−7.7%Reduced
Point72 Asset Management, L.P.503,888$12.2M0.05%+503,888New
Paradigm Biocapital Advisors LP499,496$12.1M3.20%+240,750+93.0%Added
Commodore Capital LP481,094$11.7M2.61%00.0%Unchanged
Nuveen Asset Management, LLC420,454$9.77M0.00%+157,052+59.6%Added
Nextech Invest AG375,857$9.12M2.60%00.0%Unchanged
Sphera Funds Management Ltd.362,528$8.79M1.47%−35,941−9.0%Reduced
Clough Capital Partners L P356,181$8.64M0.66%+100,500+39.3%Added
Driehaus Capital Management LLC353,912$8.59M0.11%−6,798−1.9%Reduced
Northern Trust Corp349,262$8.47M0.00%−12,434−3.4%Reduced
UBS Group AG329,578$8.00M0.00%−13,220−3.9%Reduced
PFM Health Sciences, LP284,772$6.91M0.27%+284,772New
Charles Schwab Investment Management Inc273,137$6.63M0.00%+8,486+3.2%Added
EcoR1 Capital, LLC200,000$4.85M0.15%00.0%Unchanged
Soleus Capital Management, L.P.166,736$4.04M0.62%−394,386−70.3%Reduced
Alliancebernstein L.P.144,721$3.51M0.00%+42,154+41.1%Added
Invesco Ltd.138,412$3.36M0.00%−325,790−70.2%Reduced
Rafferty Asset Management, LLC135,392$3.29M0.02%+43,385+47.2%Added
Alyeska Investment Group, L.P.131,250$3.18M0.04%+6,250+5.0%Added
Bank of New York Mellon Corp127,072$3.08M0.00%+1,601+1.3%Added
Mariner, LLC125,030$3.03M0.01%+125,030New
Goldman Sachs Group Inc119,789$2.91M0.00%−105,059−46.7%Reduced
Cypress Point Wealth Management, LLC118,573$2.88M2.92%+118,573New
Two Sigma Investments, LP114,931$2.79M0.01%+114,931New
Citadel Advisors LLC108,229$2.63M0.00%−53,727−33.2%Reduced
TD Asset Management Inc107,153$2.60M0.00%+800+0.8%Added
Bank of America Corp103,778$2.52M0.00%+2,105+2.1%Added
Schonfeld Strategic Advisors LLC89,662$2.17M0.02%+44,550+98.8%Added
Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group85,000$2.06M1.16%+40,000+88.9%Added
Manufacturers Life Insurance Company, The84,966$2.05M0.00%+65,224+330.4%Added
JPMorgan Chase & Co69,420$1.68M0.00%+40,698+141.7%Added
Bellevue Group AG54,500$1.32M0.02%+7,300+15.5%Added
Public Employees Retirement System of Ohio47,985$1.16M0.00%+10,863+29.3%Added
Eagle Health Investments LP47,200$1.15M0.28%00.0%Unchanged
Cresset Asset Management, LLC45,381$1.10M0.01%+2,000+4.6%Added
State of Wisconsin Investment Board44,500$1.08M0.00%00.0%Unchanged
Two Sigma Advisers, LP42,200$1.02M0.00%+42,200New
AlphaCrest Capital Management LLC42,027$1.02M0.06%+42,027New
Rhumbline Advisers40,699$987.0K0.00%+2,423+6.3%Added
Cubist Systematic Strategies, LLC39,024$947.0K0.01%+5,027+14.8%Added
Susquehanna International Group, LLP37,520$910.0K0.00%+2,691+7.7%Added
Simplex Trading, LLC37,246$903.0K0.03%+37,246New
HighVista Strategies LLC34,760$843.0K0.54%+3,267+10.4%Added
Swiss National Bank28,800$699.0K0.00%+2,100+7.9%Added
New York State Common Retirement Fund28,541$692.0K0.00%+18+0.1%Added
Ensign Peak Advisors, Inc28,353$688.0K0.00%00.0%Unchanged
Parametric Portfolio Associates LLC27,888$677.0K0.00%+273+1.0%Added
Barclays PLC27,643$670.0K0.00%+27,643New
Deutsche Bank AG26,990$654.0K0.00%−29,050−51.8%Reduced
California State Teachers Retirement System26,885$652.0K0.00%−4,306−13.8%Reduced
Gilder Gagnon Howe & Co LLC26,628$646.0K0.01%+26,628New
J. Goldman & Co LP25,930$629.0K0.05%+25,930New
SG3 Management, LLC25,000$607.0K0.17%+25,000New
Citigroup Inc23,818$578.0K0.00%−58,658−71.1%Reduced
Trexquant Investment LP23,636$573.0K0.03%−6,432−21.4%Reduced
Harbor Capital Advisors, Inc.21,868$531.0K0.25%−5,923−21.3%Reduced
Dynamic Technology Lab Private Ltd21,890$531.0K0.06%+9,930+83.0%Added
MetLife Investment Management21,112$512.2K0.00%+7,792+58.5%Added
Jane Street Group, LLC20,231$491.0K0.00%+20,231New
DekaBank Deutsche Girozentrale19,800$477.0K0.00%+1,800+10.0%Added
American International Group, Inc.19,181$465.0K0.00%−1,351−6.6%Reduced
Wells Fargo & Company18,784$456.0K0.00%−12,444−39.8%Reduced
Maven Securities LTD18,014$437.0K0.09%+18,014New
M&T Bank Corp17,348$420.0K0.00%+9,944+134.3%Added
Allspring Global Investments Holdings, LLC16,281$394.0K0.00%+614+3.9%Added
Squarepoint Ops LLC16,079$390.0K0.00%+3,078+23.7%Added
Jump Financial, LLC15,800$383.0K0.02%−18,189−53.5%Reduced
Voya Investment Management LLC15,161$368.0K0.00%00.0%Unchanged
Captrust Financial Advisors14,822$360.0K0.00%−4,940−25.0%Reduced
Northwestern Mutual Wealth Management Co14,540$353.0K0.00%+8,120+126.5%Added
Douglass Winthrop Advisors, LLC14,014$340.0K0.01%00.0%Unchanged
Concentric Capital Strategies, LP13,700$332.0K0.13%+13,700New
Cutler Group LP12,744$309.0K0.03%+12,744New
ProShare Advisors LLC12,296$299.0K0.00%−2,989−19.6%Reduced
Rockefeller Capital Management L.P.12,259$297.0K0.00%+11,859+2,964.8%Added
Regentatlantic Capital LLC11,380$276.0K0.01%+428+3.9%Added
Tower Research Capital LLC (TRC)11,036$268.0K0.00%+6,209+128.6%Added
Erste Asset Management GmbH10,700$257.5K0.00%+10,700New
HSBC Holdings PLC10,275$251.0K0.00%+10,275New
Shay Capital LLC10,000$243.0K0.09%−5,000−33.3%Reduced
Aj Wealth Strategies, LLC10,007$243.0K0.01%00.0%Unchanged
Credit Suisse AG9,924$240.0K0.00%+636+6.8%Added
Fox Run Management, L.L.C.8,926$217.0K0.12%+8,926New
Legal & General Group Plc7,591$185.0K0.00%−24−0.3%Reduced
Amalgamated Bank6,290$153.0K0.00%−509−7.5%Reduced