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C4 Therapeutics, Inc.

CCCC
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001662579

No open-market purchases or sales by C4 Therapeutics, Inc. insiders were filed in the last 90 days; 147 institutions reported holding it in 13F filings for Q2 2026, worth $547.6M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in C4 Therapeutics, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
119
+6 vs. Q3 2021
Shares held
35.9M
+1.40M (+4.1%) vs. Q3 2021
Total value
$1.15B
−$387.8M (−25.1%) vs. Q3 2021
New holders
22
42 more added
Sold out
16
33 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CCCC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 119 institutions
Q1 2021: 83 institutionsQ2 2021: 107 institutionsQ3 2021: 113 institutionsQ4 2021: 119 institutionsQ1 2022: 125 institutionsQ2 2022: 113 institutionsQ3 2022: 114 institutionsQ4 2022: 117 institutionsQ1 2023: 121 institutionsQ2 2023: 100 institutionsQ3 2023: 84 institutionsQ4 2023: 92 institutionsQ1 2024: 106 institutionsQ2 2024: 115 institutionsQ3 2024: 118 institutionsQ4 2024: 113 institutionsQ1 2025: 115 institutionsQ2 2025: 102 institutionsQ3 2025: 97 institutionsQ4 2025: 101 institutionsQ1 2026: 123 institutionsQ2 2026: 147 institutions
Value heldQ4 2021: $1.15B
Q1 2021: $926.8MQ2 2021: $1.21BQ3 2021: $1.54BQ4 2021: $1.15BQ1 2022: $904.8MQ2 2022: $297.2MQ3 2022: $345.9MQ4 2022: $231.4MQ1 2023: $117.5MQ2 2023: $94.1MQ3 2023: $64.5MQ4 2023: $265.6MQ1 2024: $475.6MQ2 2024: $281.3MQ3 2024: $365.9MQ4 2024: $231.8MQ1 2025: $102.6MQ2 2025: $78.2MQ3 2025: $116.6MQ4 2025: $152.5MQ1 2026: $221.3MQ2 2026: $547.6M
Institutions holding CCCC and their total value by quarter
QuarterHoldersValue
Q2 2026147$547.6M
Q1 2026123$221.3M
Q4 2025101$152.5M
Q3 202597$116.6M
Q2 2025102$78.2M
Q1 2025115$102.6M
Q4 2024113$231.8M
Q3 2024118$365.9M
Q2 2024115$281.3M
Q1 2024106$475.6M
Q4 202392$265.6M
Q3 202384$64.5M
Q2 2023100$94.1M
Q1 2023121$117.5M
Q4 2022117$231.4M
Q3 2022114$345.9M
Q2 2022113$297.2M
Q1 2022125$904.8M
Q4 2021119$1.15B
Q3 2021113$1.54B
Q2 2021107$1.21B
Q1 202183$926.8M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding C4 Therapeutics, Inc.; share changes are against Q3 2021.

Institutions holding CCCC in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Price T Rowe Associates Inc4,084,798$131.5M0.01%+127,055+3.2%Added
BlackRock Inc.3,405,982$109.7M0.00%+248,775+7.9%Added
RTW Investments, LP2,494,965$80.3M1.17%00.0%Unchanged
Perceptive Advisors LLC2,208,913$71.1M1.10%−49,653−2.2%Reduced
Vanguard Group Inc2,016,459$64.9M0.00%+77,884+4.0%Added
ArrowMark Colorado Holdings LLC1,774,504$57.1M0.46%+259,884+17.2%Added
Bain Capital Life Sciences Investors, LLC1,642,210$52.9M4.19%+10.0%Added
State Street Corp1,589,753$51.2M0.00%−68,877−4.2%Reduced
Ra Capital Management, L.P.1,377,569$44.4M0.78%00.0%Unchanged
Wasatch Advisors Inc1,295,462$41.7M0.17%−46,585−3.5%Reduced
Pictet Asset Management SA1,060,628$34.2M0.03%−37,793−3.4%Reduced
Janus Henderson Group PLC1,045,945$33.7M0.01%−2,943−0.3%Reduced
Adage Capital Partners GP, L.L.C.996,477$32.1M0.06%+185,000+22.8%Added
Morgan Stanley918,470$29.6M0.00%+628,374+216.6%Added
Millennium Management LLC753,391$24.3M0.03%+465,818+162.0%Added
Geode Capital Management, LLC686,176$22.1M0.00%+19,853+3.0%Added
FMR LLC648,981$20.9M0.00%00.0%Unchanged
Laurion Capital Management LP581,028$18.7M0.32%−81,435−12.3%Reduced
Soleus Capital Management, L.P.561,122$18.1M2.44%−189,511−25.2%Reduced
Commodore Capital LP481,094$15.5M3.59%00.0%Unchanged
Invesco Ltd.464,202$14.9M0.00%−6,321−1.3%Reduced
Sphera Funds Management Ltd.398,469$12.8M1.52%+16,695+4.4%Added
Nextech Invest AG375,857$12.1M3.19%+375,857New
Northern Trust Corp361,696$11.6M0.00%−2,257−0.6%Reduced
Driehaus Capital Management LLC360,710$11.6M0.12%−280,689−43.8%Reduced
UBS Group AG342,798$11.0M0.00%−74,555−17.9%Reduced
Charles Schwab Investment Management Inc264,651$8.52M0.00%+4,199+1.6%Added
Paradigm Biocapital Advisors LP258,746$8.33M2.38%+258,746New
Clough Capital Partners L P255,681$8.23M0.55%−91,819−26.4%Reduced
Nuveen Asset Management, LLC263,402$7.47M0.00%−43,934−14.3%Reduced
Goldman Sachs Group Inc224,848$7.24M0.00%−39,116−14.8%Reduced
EcoR1 Capital, LLC200,000$6.44M0.21%00.0%Unchanged
Citadel Advisors LLC161,956$5.21M0.01%+121,621+301.5%Added
Bank of New York Mellon Corp125,471$4.04M0.00%+12,873+11.4%Added
Alyeska Investment Group, L.P.125,000$4.03M0.05%00.0%Unchanged
TD Asset Management Inc106,353$3.42M0.00%+6,600+6.6%Added
Alliancebernstein L.P.102,567$3.30M0.00%+21,370+26.3%Added
Bank of America Corp101,673$3.27M0.00%+80,122+371.8%Added
Rafferty Asset Management, LLC92,007$2.96M0.02%+32,956+55.8%Added
Citigroup Inc82,476$2.66M0.00%+15,712+23.5%Added
Walleye Capital LLC81,720$2.63M0.09%+81,720New
Voloridge Investment Management, LLC60,903$1.96M0.01%−44,411−42.2%Reduced
Deutsche Bank AG56,040$1.80M0.00%+31,854+131.7%Added
Bank of Montreal54,100$1.78M0.00%+54,100New
Bellevue Group AG47,200$1.52M0.02%00.0%Unchanged
Eagle Health Investments LP47,200$1.52M0.37%00.0%Unchanged
Schonfeld Strategic Advisors LLC45,112$1.45M0.01%−17,141−27.5%Reduced
Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group45,000$1.45M0.99%+45,000New
State of Wisconsin Investment Board44,500$1.43M0.00%00.0%Unchanged
Cresset Asset Management, LLC43,381$1.40M0.01%+43,381New
Federated Hermes, Inc.41,897$1.35M0.00%−16,715−28.5%Reduced
Rhumbline Advisers38,276$1.23M0.00%+81+0.2%Added
Public Employees Retirement System of Ohio37,122$1.20M0.00%00.0%Unchanged
Goldstream Capital Management Ltd36,193$1.17M0.29%+36,193New
Susquehanna International Group, LLP34,829$1.12M0.00%−8,586−19.8%Reduced
Jump Financial, LLC33,989$1.09M0.07%−5,711−14.4%Reduced
Cubist Systematic Strategies, LLC33,997$1.09M0.01%−3,303−8.9%Reduced
HighVista Strategies LLC31,493$1.01M0.81%+2,152+7.3%Added
Renaissance Technologies LLC31,300$1.01M0.00%+31,300New
Wells Fargo & Company31,228$1.00M0.00%+2,852+10.1%Added
California State Teachers Retirement System31,191$1.00M0.00%+1,459+4.9%Added
Trexquant Investment LP30,068$968.0K0.06%+30,068New
Pura Vida Investments, LLC29,244$942.0K0.10%+9,244+46.2%Added
JPMorgan Chase & Co28,722$925.0K0.00%−26,107−47.6%Reduced
New York State Common Retirement Fund28,523$918.0K0.00%+3,568+14.3%Added
Ensign Peak Advisors, Inc28,353$913.0K0.00%+2,560+9.9%Added
Harbor Capital Advisors, Inc.27,791$895.0K0.33%+27,791New
Parametric Portfolio Associates LLC27,615$889.0K0.00%+673+2.5%Added
Jennison Associates LLC27,001$869.0K0.00%−458,312−94.4%Reduced
Swiss National Bank26,700$860.0K0.00%+2,900+12.2%Added
D. E. Shaw & Co., Inc.25,735$829.0K0.00%+15,852+160.4%Added
Tudor Investment Corp Et Al21,283$685.0K0.01%+21,283New
American International Group, Inc.20,532$661.0K0.00%−614−2.9%Reduced
Manufacturers Life Insurance Company, The19,742$646.0K0.00%+352+1.8%Added
Vontobel Holding Ltd.20,000$644.0K0.01%00.0%Unchanged
Captrust Financial Advisors19,762$636.0K0.00%−6,587−25.0%Reduced
DekaBank Deutsche Girozentrale18,000$593.0K0.00%+18,000New
Victory Capital Management Inc16,530$532.0K0.00%+6,387+63.0%Added
Martingale Asset Management L P16,109$519.0K0.01%+16,109New
Allspring Global Investments Holdings, LLC15,667$504.0K0.00%+15,667New
ProShare Advisors LLC15,285$492.0K0.00%+10,334+208.7%Added
Voya Investment Management LLC15,161$488.0K0.00%+297+2.0%Added
Shay Capital LLC15,000$483.0K0.18%−22,500−60.0%Reduced
Douglass Winthrop Advisors, LLC14,014$451.0K0.01%00.0%Unchanged
MetLife Investment Management13,320$428.9K0.00%00.0%Unchanged
Squarepoint Ops LLC13,001$419.0K0.00%+13,001New
Dynamic Technology Lab Private Ltd11,960$385.0K0.04%+11,960New
Royal Bank of Canada11,475$369.0K0.00%+3,850+50.5%Added
Regentatlantic Capital LLC10,952$353.0K0.01%−1,626−12.9%Reduced
EMC Capital Management10,619$342.0K0.18%00.0%Unchanged
Metropolitan Life Insurance Co10,375$334.1K0.00%00.0%Unchanged
Aj Wealth Strategies, LLC10,007$322.0K0.02%00.0%Unchanged
Credit Suisse AG9,288$298.0K0.00%+758+8.9%Added
Dymon Asia Capital (Singapore) Pte. Ltd.8,250$266.0K0.16%−8,250−50.0%Reduced
Handelsbanken Fonder AB8,200$264.0K0.00%00.0%Unchanged
Legal & General Group Plc7,615$245.0K0.00%+524+7.4%Added
M&T Bank Corp7,404$238.0K0.00%+1,447+24.3%Added
SG Americas Securities, LLC7,149$230.0K0.00%−4,592−39.1%Reduced
Amalgamated Bank6,799$219.0K0.00%−65−0.9%Reduced
Principal Financial Group Inc6,570$212.0K0.00%−1,536−18.9%Reduced