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C4 Therapeutics, Inc.

CCCC
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001662579

No open-market purchases or sales by C4 Therapeutics, Inc. insiders were filed in the last 90 days; 147 institutions reported holding it in 13F filings for Q2 2026, worth $547.6M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in C4 Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
123
+23 vs. Q4 2025
Shares held
84.5M
+9.04M (+12.0%) vs. Q4 2025
Total value
$221.3M
+$77.2M (+53.6%) vs. Q4 2025
New holders
34
41 more added
Sold out
11
30 more reduced

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CCCC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 123 institutions
Q1 2021: 83 institutionsQ2 2021: 107 institutionsQ3 2021: 113 institutionsQ4 2021: 119 institutionsQ1 2022: 125 institutionsQ2 2022: 113 institutionsQ3 2022: 114 institutionsQ4 2022: 117 institutionsQ1 2023: 121 institutionsQ2 2023: 100 institutionsQ3 2023: 84 institutionsQ4 2023: 92 institutionsQ1 2024: 106 institutionsQ2 2024: 115 institutionsQ3 2024: 118 institutionsQ4 2024: 113 institutionsQ1 2025: 115 institutionsQ2 2025: 102 institutionsQ3 2025: 97 institutionsQ4 2025: 101 institutionsQ1 2026: 123 institutionsQ2 2026: 147 institutions
Value heldQ1 2026: $221.3M
Q1 2021: $926.8MQ2 2021: $1.21BQ3 2021: $1.54BQ4 2021: $1.15BQ1 2022: $904.8MQ2 2022: $297.2MQ3 2022: $345.9MQ4 2022: $231.4MQ1 2023: $117.5MQ2 2023: $94.1MQ3 2023: $64.5MQ4 2023: $265.6MQ1 2024: $475.6MQ2 2024: $281.3MQ3 2024: $365.9MQ4 2024: $231.8MQ1 2025: $102.6MQ2 2025: $78.2MQ3 2025: $116.6MQ4 2025: $152.5MQ1 2026: $221.3MQ2 2026: $547.6M
Institutions holding CCCC and their total value by quarter
QuarterHoldersValue
Q2 2026147$547.6M
Q1 2026123$221.3M
Q4 2025101$152.5M
Q3 202597$116.6M
Q2 2025102$78.2M
Q1 2025115$102.6M
Q4 2024113$231.8M
Q3 2024118$365.9M
Q2 2024115$281.3M
Q1 2024106$475.6M
Q4 202392$265.6M
Q3 202384$64.5M
Q2 2023100$94.1M
Q1 2023121$117.5M
Q4 2022117$231.4M
Q3 2022114$345.9M
Q2 2022113$297.2M
Q1 2022125$904.8M
Q4 2021119$1.15B
Q3 2021113$1.54B
Q2 2021107$1.21B
Q1 202183$926.8M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding C4 Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding CCCC in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Hantz Financial Services, Inc.3$00.00%+3New
Advisory Services Network, LLC74$1950.00%+74New
Harbour Investments, Inc.90$2370.00%+90New
SBI Securities Co., Ltd.101$2660.00%+1+1.0%Added
Nisa Investment Advisors, LLC156$4100.00%00.0%Unchanged
Jones Financial Companies LLLP278$6700.00%+278New
SRS Capital Advisors, Inc.319$8390.00%+300+1,578.9%Added
Royal Bank of Canada680$1.00K0.00%+9+1.3%Added
Fortitude Family Office, LLC435$1.14K0.00%+435New
Caitong International Asset Management Co., Ltd592$1.56K0.00%+592New
Federated Hermes, Inc.1,878$4.94K0.00%+1,878New
Owl Creek Wealth Partners LLC2,140$5.63K0.00%+2,140New
GF Fund Management Co. Ltd.2,165$5.69K0.00%+262+13.8%Added
Rhumbline Advisers2,716$7.14K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec3,000$7.89K0.00%+2,000+200.0%Added
NBC Securities, Inc.4,000$10.5K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.4,544$11.9K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.5,090$13.4K0.00%+381+8.1%Added
Tower Research Capital LLC (TRC)9,849$25.9K0.00%−16,131−62.1%Reduced
Blackston Financial Advisory Group, LLC10,000$26.3K0.02%00.0%Unchanged
Bronte Capital Management Pty Ltd.10,033$26.4K0.00%00.0%Unchanged
Abel Hall, LLC10,088$26.5K0.01%−52−0.5%Reduced
Ethic Inc.10,131$26.6K0.00%−147−1.4%Reduced
Simplicity Wealth,LLC10,201$26.8K0.00%−10.0%Reduced
Two Sigma Securities, LLC10,203$26.8K0.00%+10,203New
SummitTX Capital, L.P.10,466$27.5K0.00%+10,466New
CTC Alternative Strategies, Ltd.10,792$28.4K0.06%+10,792New
Northern Lights Advisors, Inc.12,930$34.0K0.02%00.0%Unchanged
HSBC Holdings PLC13,629$36.0K0.00%00.0%Unchanged
Nine Masts Capital Ltd14,157$37.2K0.01%+2,685+23.4%Added
Ewa, LLC14,572$38.3K0.01%−2,317−13.7%Reduced
Dauntless Investment Group, LLC15,000$39.5K0.11%+15,000New
JustInvest LLC15,249$40.1K0.00%+25+0.2%Added
Prudential Financial Inc15,950$41.9K0.00%+900+6.0%Added
China Universal Asset Management Co., Ltd.17,316$45.5K0.00%+1,524+9.7%Added
Callan Family Office, LLC19,146$50.4K0.00%−12,597−39.7%Reduced
CI Private Wealth, LLC21,387$56.2K0.00%00.0%Unchanged
Graham Capital Management, L.P.23,733$62.4K0.00%−78,465−76.8%Reduced
Schonfeld Strategic Advisors LLC23,944$63.0K0.00%+23,944New
Winton Group Ltd24,700$65.0K0.00%+24,700New
Cresset Asset Management, LLC25,000$65.8K0.00%00.0%Unchanged
SEI Investments Co25,134$66.1K0.00%+25,134New
Catalyst Funds Management Pty Ltd25,740$67.7K0.01%−16,760−39.4%Reduced
Jefferies Financial Group Inc.26,120$68.7K0.00%−9,220−26.1%Reduced
Farallon Capital Management, L.L.C.28,000$73.6K0.00%00.0%Unchanged
Prelude Capital Management, LLC30,957$81.4K0.01%+30,957New
Vanguard Global Advisers, LLC33,832$89.0K0.00%+33,832New
Diametric Capital, LP34,594$91.0K0.02%+34,594New
Colony Group, LLC38,187$100.4K0.00%00.0%Unchanged
Squarepoint Ops LLC40,664$106.9K0.00%−95,390−70.1%Reduced
Citigroup Inc42,428$111.6K0.00%−7,412−14.9%Reduced
ADAR1 Capital Management, LLC43,000$113.1K0.01%+43,000New
XTX Topco Ltd47,151$124.0K0.00%−57,307−54.9%Reduced
ExodusPoint Capital Management, LP47,507$124.9K0.00%−14,658−23.6%Reduced
Readystate Asset Management LP49,586$130.4K0.01%+49,586New
Seven Fleet Capital Management LP57,076$150.1K0.05%+57,076New
Omers Administration Corp59,700$157.0K0.00%−58,000−49.3%Reduced
Intrepid Family Office LLC60,000$157.8K0.14%+5,000+9.1%Added
Jain Global LLC62,390$164.1K0.00%+49,628+388.9%Added
Quadrature Capital Ltd62,760$165.1K0.00%−70,352−52.9%Reduced
Crestwood Advisors Group LLC66,536$175.0K0.00%00.0%Unchanged
Price T Rowe Associates Inc71,546$189.0K0.00%+59,146+477.0%Added
Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group85,000$223.6K0.09%00.0%Unchanged
American Century Companies Inc85,444$224.7K0.00%+17,199+25.2%Added
Axq Capital, LP86,278$226.9K0.03%+86,278New
Panagora Asset Management Inc86,760$228.2K0.00%+86,760New
Brevan Howard Capital Management LP92,647$243.7K0.00%+92,647New
Verdad Advisers, LP109,407$287.7K0.32%+109,407New
Mariner, LLC127,517$334.2K0.00%−533−0.4%Reduced
Hudson Bay Capital Management LP130,081$342.1K0.00%+18,530+16.6%Added
Bridgeway Capital Management, LLC131,100$344.8K0.01%00.0%Unchanged
Canada Pension Plan Investment Board135,600$356.6K0.00%+106,100+359.7%Added
Atom Investors LP136,047$357.8K0.03%+31,083+29.6%Added
Marshall Wace, LLP155,495$409.0K0.00%−109,532−41.3%Reduced
HRT Financial LP162,930$428.0K0.00%+162,930New
Point72 Asset Management, L.P.169,096$444.7K0.00%−9,270,232−98.2%Reduced
Toronto Dominion Bank174,663$459.4K0.00%+174,663New
Northern Trust Corp189,479$498.3K0.00%+23,272+14.0%Added
BNP Paribas Arbitrage, SA190,348$500.6K0.00%+188,187+8,708.3%Added
UBS Group AG215,877$567.8K0.00%+163,125+309.2%Added
Hennion & Walsh Asset Management, Inc.223,168$586.9K0.02%−13,969−5.9%Reduced
Walleye Capital LLC239,118$628.9K0.00%−204,223−46.1%Reduced
Invesco Ltd.244,507$643.1K0.00%−23,843−8.9%Reduced
LPL Financial LLC246,800$649.1K0.00%+3,495+1.4%Added
Man Group plc256,468$674.5K0.00%+100,370+64.3%Added
Susquehanna Portfolio Strategies, LLC260,279$684.5K0.01%−11,774−4.3%Reduced
Jacobs Levy Equity Management, Inc264,620$696.0K0.00%+264,620New
FMR LLC272,368$716.3K0.00%+17,962+7.1%Added
Connor, Clark & Lunn Investment Management Ltd.277,183$729.0K0.00%+239,462+634.8%Added
683 Capital Management, LLC300,000$789.0K0.07%−100,000−25.0%Reduced
Barclays PLC317,877$836.0K0.00%+98,673+45.0%Added
State Street Corp382,973$1.01M0.00%+40,200+11.7%Added
Platinum Investment Management Ltd384,766$1.01M0.26%+384,766New
Dimensional Fund Advisors LP442,518$1.16M0.00%+146,038+49.3%Added
Charles Schwab Investment Management Inc452,228$1.19M0.00%+2,796+0.6%Added
StemPoint Capital LP453,236$1.19M0.23%+453,236New
Vanguard Fiduciary Trust Co484,131$1.27M0.00%+484,131New
Qube Research & Technologies Ltd752,114$1.98M0.00%+461,880+159.1%Added
Congress Asset Management Co830,624$2.18M0.02%+830,624New
OrbiMed Advisors LLC856,353$2.25M0.05%−548,549−39.0%Reduced