Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 852
- +55 vs. Q3 2025
- Shares held
- 132.8M
- +3.06M (+2.4%) vs. Q3 2025
- Total value
- $52.7B
- −$6.43B (−10.9%) vs. Q3 2025
- New holders
- 172
- 290 more added
- Sold out
- 117
- 291 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| LPL Financial LLC | 45,919 | $18.3M | 0.00% | −2,561−5.3% | Reduced |
| Forsta Ap-Fonden | 46,420 | $18.5M | 0.11% | +18,520+66.4% | Added |
| Intech Investment Management LLC | 46,710 | $18.6M | 0.17% | +40,898+703.7% | Added |
| Parkman Healthcare Partners LLC | 47,703 | $19.0M | 1.81% | −39,987−45.6% | Reduced |
| Allianz Asset Management GmbH | 47,875 | $19.0M | 0.02% | −58,941−55.2% | Reduced |
| Antipodes Partners Ltd | 47,886 | $19.0M | 0.40% | +15,930+49.8% | Added |
| Van Eck Associates Corp | 47,922 | $19.1M | 0.02% | +6,789+16.5% | Added |
| Andra AP-fonden | 48,540 | $19.3M | 0.24% | +27,840+134.5% | Added |
| Frontier Capital Management Co LLC | 48,859 | $19.4M | 0.21% | −70,019−58.9% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 49,462 | $19.7M | 0.05% | +43,302+703.0% | Added |
| KLP Kapitalforvaltning AS | 50,440 | $20.1M | 0.08% | +1,640+3.4% | Added |
| Voleon Capital Management LP | 51,117 | $20.3M | 0.44% | +17,152+50.5% | Added |
| Caisse de Depot Et Placement du Quebec | 51,598 | $20.5M | 0.03% | +33,772+189.5% | Added |
| Treasurer of the State of North Carolina | 53,114 | $21.1M | 0.07% | −3,009−5.4% | Reduced |
| Great West Life Assurance Co | 57,879 | $23.0M | 0.04% | −35,213−37.8% | Reduced |
| Ensign Peak Advisors, Inc | 57,932 | $23.0M | 0.04% | −9,801−14.5% | Reduced |
| LMR Partners LLP | 59,022 | $23.5M | 0.23% | +59,022 | New |
| Capital International Inc | 59,552 | $23.7M | 0.19% | −16,086−21.3% | Reduced |
| Integral Health Asset Management, LLC | 60,000 | $23.9M | 1.21% | 00.0% | Unchanged |
| Swedbank AB | 61,942 | $24.6M | 0.02% | −1,636−2.6% | Reduced |
| Manufacturers Life Insurance Company, The | 63,412 | $25.2M | 0.02% | −4,260−6.3% | Reduced |
| New York State Common Retirement Fund | 64,424 | $25.6M | 0.03% | 00.0% | Unchanged |
| Ieq Capital, LLC | 64,905 | $25.8M | 0.08% | +2,728+4.4% | Added |
| Asset Management One Co.,Ltd. | 65,187 | $26.0M | 0.07% | −4,423−6.4% | Reduced |
| State of Wisconsin Investment Board | 66,065 | $26.3M | 0.06% | −2,464−3.6% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 66,218 | $26.3M | 0.11% | −13,434−16.9% | Reduced |
| National Bank of Canada | 66,433 | $26.4M | 0.03% | +65,476+6,841.8% | Added |
| Danske Bank A/S | 67,201 | $26.7M | 0.06% | +9,794+17.1% | Added |
| Capital International Ltd | 67,667 | $26.9M | 0.95% | −10,556−13.5% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 67,935 | $27.0M | 0.35% | 00.0% | Unchanged |
| Schroder Investment Management Group | 68,049 | $27.0M | 0.02% | +57,231+529.0% | Added |
| Driehaus Capital Management LLC | 69,778 | $27.7M | 0.19% | +8,399+13.7% | Added |
| Soleus Capital Management, L.P. | 70,000 | $27.8M | 1.18% | +54,750+359.0% | Added |
| Fiera Capital Corp | 70,720 | $28.1M | 0.09% | +16,916+31.4% | Added |
| Rock Springs Capital Management LP | 71,250 | $28.3M | 1.45% | −3,000−4.0% | Reduced |
| Storebrand Asset Management AS | 74,780 | $29.7M | 0.08% | +2,763+3.8% | Added |
| Casdin Capital, LLC | 75,000 | $29.8M | 1.85% | +20,000+36.4% | Added |
| Millennium Management LLC | 75,430 | $30.0M | 0.02% | −474,501−86.3% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 79,397 | $31.6M | 0.07% | +1,936+2.5% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 80,101 | $31.9M | 0.05% | +69,430+650.6% | Added |
| Hudson Bay Capital Management LP | 85,000 | $33.8M | 0.19% | +75,589+803.2% | Added |
| Bridgewater Associates, LP | 85,617 | $34.0M | 0.12% | +51,706+152.5% | Added |
| Life Cycle Investment Partners Ltd | 88,076 | $35.0M | 0.25% | +88,076 | New |
| HSBC Holdings PLC | 89,517 | $35.7M | 0.02% | +16,503+22.6% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 89,804 | $35.7M | 0.08% | +48,860+119.3% | Added |
| SG Americas Securities, LLC | 90,921 | $36.2M | 0.05% | +59,071+185.5% | Added |
| Westfield Capital Management Co LP | 93,444 | $37.2M | 0.15% | +5,536+6.3% | Added |
| FIL Ltd | 94,164 | $37.4M | 0.03% | −41,320−30.5% | Reduced |
| Nomura Asset Management Co Ltd | 94,278 | $37.5M | 0.09% | +4,409+4.9% | Added |
| Pinebridge Investments LLC | 100,199 | $39.8M | 0.29% | +100,199 | New |
| HighTower Advisors, LLC | 106,491 | $42.3M | 0.05% | −4,133−3.7% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 109,604 | $43.6M | 0.05% | +77,235+238.6% | Added |
| Tremblant Capital Group | 110,132 | $43.8M | 1.12% | +110,132 | New |
| Aviva PLC | 110,662 | $44.0M | 0.07% | +7,456+7.2% | Added |
| SEI Investments Co | 111,112 | $44.2M | 0.04% | +16,631+17.6% | Added |
| State Board of Administration of Florida Retirement System | 114,603 | $45.6M | 0.08% | −2,623−2.2% | Reduced |
| Neuberger Berman Group LLC | 115,203 | $45.8M | 0.03% | −15,341−11.8% | Reduced |
| Capital International Sarl | 119,352 | $47.5M | 0.76% | −10,350−8.0% | Reduced |
| Envestnet Asset Management Inc | 120,521 | $47.9M | 0.01% | +1,557+1.3% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 124,645 | $49.4M | 0.08% | +14,093+12.7% | Added |
| Standard Life Aberdeen plc | 132,846 | $52.8M | 0.08% | −24,550−15.6% | Reduced |
| Handelsbanken Fonder AB | 136,185 | $54.2M | 0.16% | −19,184−12.3% | Reduced |
| Janus Henderson Group PLC | 136,425 | $54.3M | 0.02% | +570+0.4% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 138,795 | $55.5M | 0.04% | +18,008+14.9% | Added |
| Man Group plc | 144,210 | $57.3M | 0.11% | +72,537+101.2% | Added |
| Robeco Institutional Asset Management B.V. | 144,721 | $57.5M | 0.08% | +31,647+28.0% | Added |
| SCS Capital Management LLC | 149,611 | $59.5M | 0.63% | −1,057−0.7% | Reduced |
| Voloridge Investment Management, LLC | 160,577 | $63.9M | 0.22% | −196,229−55.0% | Reduced |
| Russell Investments Group, Ltd. | 165,740 | $65.9M | 0.07% | −30,176−15.4% | Reduced |
| National Pension Service | 168,149 | $66.9M | 0.05% | −9,089−5.1% | Reduced |
| Citigroup Inc | 172,562 | $68.6M | 0.05% | +111,696+183.5% | Added |
| Ameriprise Financial Inc | 181,137 | $72.0M | 0.02% | −44,742−19.8% | Reduced |
| Korea Investment CORP | 189,769 | $75.5M | 0.15% | −7,143−3.6% | Reduced |
| Susquehanna International Group, LLP | 191,820 | $76.3M | 0.10% | −385,812−66.8% | Reduced |
| Rhumbline Advisers | 195,266 | $77.6M | 0.06% | −1,231−0.6% | Reduced |
| Voya Investment Management LLC | 198,613 | $79.0M | 0.08% | −174,743−46.8% | Reduced |
| CIBC Private Wealth Group, LLC | 200,425 | $79.7M | 0.13% | −13,788−6.4% | Reduced |
| California State Teachers Retirement System | 201,816 | $80.3M | 0.08% | −1,962−1.0% | Reduced |
| ProShare Advisors LLC | 211,077 | $83.9M | 0.15% | +206,446+4,457.9% | Added |
| FengHe Fund Management Pte. Ltd. | 218,700 | $87.0M | 4.90% | +218,700 | New |
| Victory Capital Management Inc | 220,866 | $87.8M | 0.05% | +40,517+22.5% | Added |
| Barclays PLC | 222,561 | $88.5M | 0.04% | +128,153+135.7% | Added |
| Candriam Luxembourg S.C.A. | 224,330 | $89.2M | 0.44% | +11,914+5.6% | Added |
| California Public Employees Retirement System | 237,005 | $94.2M | 0.05% | +7,364+3.2% | Added |
| Polar Capital Holdings Plc | 240,606 | $95.7M | 0.44% | −10,854−4.3% | Reduced |
| Royal London Asset Management Ltd | 253,072 | $100.6M | 0.21% | −4,241−1.6% | Reduced |
| First Trust Advisors LP | 256,954 | $102.2M | 0.07% | +46,571+22.1% | Added |
| Wells Fargo & Company | 257,640 | $102.5M | 0.02% | −22,928−8.2% | Reduced |
| Canada Pension Plan Investment Board | 258,711 | $102.9M | 0.07% | +122,380+89.8% | Added |
| TD Asset Management Inc | 269,101 | $107.0M | 0.09% | −43,416−13.9% | Reduced |
| Congress Asset Management Co | 269,239 | $107.1M | 0.75% | +150,439+126.6% | Added |
| Los Angeles Capital Management LLC | 240,052 | $107.9M | 0.37% | +80,658+50.6% | Added |
| Jennison Associates LLC | 277,759 | $110.5M | 0.07% | −27,104−8.9% | Reduced |
| Allspring Global Investments Holdings, LLC | 278,657 | $111.5M | 0.18% | −32,147−10.3% | Reduced |
| OrbiMed Advisors LLC | 288,800 | $114.8M | 2.35% | −12,800−4.2% | Reduced |
| Dimensional Fund Advisors LP | 301,865 | $120.0M | 0.03% | +59,931+24.8% | Added |
| Jane Street Group, LLC | 311,288 | $123.8M | 0.15% | −647,462−67.5% | Reduced |
| Nomura Asset Management International Inc. | 311,757 | $124.0M | 0.19% | +311,757 | New |
| Pictet Asset Management Holding SA | 316,053 | $125.8M | 0.12% | −71,493−18.4% | Reduced |
| Gilder Gagnon Howe & Co LLC | 319,305 | $127.0M | 1.34% | −10,016−3.0% | Reduced |