Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 852
- +55 vs. Q3 2025
- Shares held
- 132.8M
- +3.06M (+2.4%) vs. Q3 2025
- Total value
- $52.7B
- −$6.43B (−10.9%) vs. Q3 2025
- New holders
- 172
- 290 more added
- Sold out
- 117
- 291 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sivia Capital Partners, LLC | 1,997 | $794.1K | 0.16% | +901+82.2% | Added |
| Security National Bank of So Dak | 2,000 | $795.3K | 0.39% | 00.0% | Unchanged |
| TCW Group Inc | 2,000 | $795.3K | 0.01% | +2,000 | New |
| Elm Partners Management LLC | 2,008 | $798.5K | 0.04% | +2,008 | New |
| Archford Capital Strategies, LLC | 2,024 | $804.8K | 0.09% | 00.0% | Unchanged |
| DRW Securities, LLC | 2,041 | $811.6K | 0.06% | +2,041 | New |
| Alpine Global Management, LLC | 2,062 | $820.0K | 0.18% | +2,062 | New |
| ICICI Prudential Asset Management Co Ltd | 2,120 | $843.0K | 0.10% | +2,120 | New |
| Private Advisory Group LLC | 2,155 | $856.9K | 0.07% | +736+51.9% | Added |
| Twin Capital Management Inc | 2,208 | $878.0K | 0.11% | +2,208 | New |
| Capstone Capital Management Ltd | 2,301 | $915.0K | 0.88% | +2,301 | New |
| Vontobel Holding Ltd. | 2,319 | $922.2K | 0.00% | −463−16.6% | Reduced |
| Nixon Peabody Trust Co | 2,337 | $929.3K | 0.07% | −10−0.4% | Reduced |
| Exchange Traded Concepts, LLC | 2,361 | $938.9K | 0.01% | +288+13.9% | Added |
| QRG Capital Management, Inc. | 2,363 | $939.5K | 0.01% | −72−3.0% | Reduced |
| Horizon Kinetics Asset Management LLC | 2,376 | $944.8K | 0.01% | −104−4.2% | Reduced |
| Park Avenue Securities LLC | 2,391 | $951.0K | 0.01% | −340−12.4% | Reduced |
| Central Pacific Bank - Trust Division | 2,413 | $959.5K | 0.12% | −222−8.4% | Reduced |
| Inceptionr LLC | 2,415 | $960.3K | 0.27% | −1,104−31.4% | Reduced |
| Draper Asset Management, LLC | 2,422 | $963.1K | 0.51% | +1,680+226.4% | Added |
| ING Groep NV | 2,444 | $971.9K | 0.01% | +2,444 | New |
| United Capital Financial Advisers, LLC | 2,449 | $973.9K | 0.01% | +304+14.2% | Added |
| Portman Square Capital LLP | 2,457 | $977.0K | 0.17% | +2,457 | New |
| Theory Financial LLC | 2,744 | $991.5K | 0.33% | +2,744 | New |
| UniSuper Management Pty Ltd | 2,500 | $994.1K | 0.01% | +300+13.6% | Added |
| Oxford Asset Management LLP | 2,534 | $1.01M | 0.36% | −816−24.4% | Reduced |
| Everhart Financial Group, Inc. | 2,541 | $1.01M | 0.09% | −89−3.4% | Reduced |
| RSM US Wealth Management LLC | 2,575 | $1.02M | 0.01% | −189−6.8% | Reduced |
| Principal Securities, Inc. | 2,626 | $1.04M | 0.02% | +188+7.7% | Added |
| RMB Capital Management, LLC | 2,662 | $1.06M | 0.02% | +2,662 | New |
| Mitsubishi UFJ Morgan Stanley Securities Co., Ltd. | 2,682 | $1.07M | 1.68% | +2,682 | New |
| Financiere des Professionnels - Fonds d,investissement inc. | 2,689 | $1.07M | 0.06% | +885+49.1% | Added |
| Anchor Investment Management, LLC | 2,695 | $1.07M | 0.09% | +446+19.8% | Added |
| Wiley Bros.-Aintree Capital, LLC | 2,697 | $1.07M | 0.01% | −46−1.7% | Reduced |
| Regal Investment Advisors LLC | 2,714 | $1.08M | 0.06% | +12+0.4% | Added |
| Western Financial Corp | 2,731 | $1.09M | 0.43% | +7+0.3% | Added |
| Greenleaf Trust | 2,733 | $1.09M | 0.01% | −2−0.1% | Reduced |
| Shepherd Financial Partners LLC | 2,736 | $1.09M | 0.10% | 00.0% | Unchanged |
| Robertson Stephens Wealth Management, LLC | 2,800 | $1.11M | 0.03% | +2,800 | New |
| Hall Laurie J Trustee | 2,812 | $1.12M | 0.37% | −438−13.5% | Reduced |
| Fig Financial Advisory Services Inc | 2,845 | $1.13M | 0.72% | +33+1.2% | Added |
| Generali Investments CEE, investicni spolecnost, a.s. | 2,900 | $1.15M | 0.08% | 00.0% | Unchanged |
| Virtu Financial LLC | 2,941 | $1.17M | 0.05% | −8,715−74.8% | Reduced |
| Orion Capital Management LLC | 2,967 | $1.18M | 0.40% | −173−5.5% | Reduced |
| Everence Capital Management Inc | 2,970 | $1.18M | 0.07% | 00.0% | Unchanged |
| Sectoral Asset Management Inc | 2,990 | $1.19M | 0.95% | −283−8.6% | Reduced |
| Sivik Global Healthcare LLC | 3,000 | $1.19M | 0.58% | +3,000 | New |
| GWM Advisors LLC | 3,017 | $1.20M | 0.00% | +1,493+98.0% | Added |
| Balyasny Asset Management LLC | 3,026 | $1.20M | 0.00% | −7,234−70.5% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 3,032 | $1.21M | 0.00% | −148−4.7% | Reduced |
| Polymer Capital Management (US) LLC | 3,070 | $1.22M | 0.16% | +2,262+280.0% | Added |
| Grandfield & Dodd, LLC | 3,129 | $1.24M | 0.07% | +9+0.3% | Added |
| Sumitomo Life Insurance Co | 3,194 | $1.27M | 0.03% | +27+0.9% | Added |
| Kennedy Capital Management, Inc. | 3,215 | $1.28M | 0.03% | −5−0.2% | Reduced |
| Ethic Inc. | 3,218 | $1.28M | 0.02% | +1,034+47.3% | Added |
| Values First Advisors, Inc. | 3,226 | $1.28M | 0.67% | −656−16.9% | Reduced |
| Kentucky Retirement Systems Insurance Trust Fund | 3,285 | $1.31M | 0.08% | 00.0% | Unchanged |
| SBI Okasan Asset Management Co.Ltd. | 3,290 | $1.31M | 0.07% | +3,290 | New |
| Keybank National Association | 3,335 | $1.33M | 0.00% | −725−17.9% | Reduced |
| Spectrum Planning & Advisory Services Inc. | 3,350 | $1.33M | 0.69% | 00.0% | Unchanged |
| J. Goldman & Co LP | 3,368 | $1.34M | 0.05% | +3,368 | New |
| SummitTX Capital, L.P. | 3,465 | $1.38M | 0.04% | −4,060−54.0% | Reduced |
| FORA Capital, LLC | 3,466 | $1.38M | 0.17% | +747+27.5% | Added |
| Principal Financial Group Inc | 3,498 | $1.39M | 0.00% | −1,922−35.5% | Reduced |
| Bamco Inc | 3,500 | $1.39M | 0.00% | 00.0% | Unchanged |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 3,500 | $1.39M | 0.00% | 00.0% | Unchanged |
| Laird Norton Trust Company, LLC | 3,501 | $1.39M | 0.03% | +3,501 | New |
| Summit Trail Advisors, LLC | 3,514 | $1.40M | 0.02% | +79+2.3% | Added |
| Vestcor Inc | 3,533 | $1.41M | 0.04% | +1,006+39.8% | Added |
| Sterling Capital Management LLC | 3,557 | $1.41M | 0.02% | +730+25.8% | Added |
| Callan Family Office, LLC | 3,614 | $1.44M | 0.03% | +858+31.1% | Added |
| Brandywine Managers, LLC | 3,618 | $1.44M | 0.71% | −100−2.7% | Reduced |
| Twin Tree Management, LP | 3,641 | $1.45M | 0.15% | −12,364−77.3% | Reduced |
| Howard Capital Management Inc. | 3,680 | $1.46M | 0.02% | +2,826+330.9% | Added |
| Ambassador Advisors, LLC | 3,774 | $1.50M | 0.22% | +3,774 | New |
| 683 Capital Management, LLC | 3,782 | $1.50M | 0.13% | +3,782 | New |
| Atlantic Trust, LLC | 3,966 | $1.58M | 0.25% | −28−0.7% | Reduced |
| Verition Fund Management LLC | 4,005 | $1.59M | 0.01% | −13,028−76.5% | Reduced |
| Gilbert & Cook, Inc. | 4,018 | $1.60M | 0.20% | −1,490−27.1% | Reduced |
| Comerica Bank | 4,040 | $1.61M | 0.01% | −7,750−65.7% | Reduced |
| Buckingham Strategic Partners | 4,095 | $1.63M | 0.02% | −1,032−20.1% | Reduced |
| Pallas Capital Advisors LLC | 4,109 | $1.63M | 0.05% | −316−7.1% | Reduced |
| Metis Global Partners, LLC | 4,185 | $1.66M | 0.04% | −126−2.9% | Reduced |
| Sequoia Financial Advisors, LLC | 4,212 | $1.67M | 0.01% | −94−2.2% | Reduced |
| Integrated Wealth Concepts LLC | 4,240 | $1.69M | 0.02% | −396−8.5% | Reduced |
| Howland Capital Management LLC | 4,243 | $1.69M | 0.06% | 00.0% | Unchanged |
| Hunting Hill Global Capital, LLC | 4,259 | $1.69M | 1.68% | +4,259 | New |
| NLB Skladi, upravljanje premozenja, d.o.o. | 4,300 | $1.71M | 0.08% | +4,300 | New |
| Advisors Asset Management, Inc. | 4,303 | $1.71M | 0.03% | −219−4.8% | Reduced |
| Quantitative Investment Management, LLC | 4,331 | $1.72M | 0.17% | +4,331 | New |
| Envestnet Portfolio Solutions, Inc. | 4,345 | $1.73M | 0.01% | +3,018+227.4% | Added |
| Brinker Capital Investments, LLC | 4,405 | $1.75M | 0.01% | −993−18.4% | Reduced |
| Brevan Howard Capital Management LP | 4,437 | $1.76M | 0.03% | −1,733−28.1% | Reduced |
| Norinchukin Bank, The | 4,487 | $1.78M | 0.02% | +4,487 | New |
| Merit Financial Group, LLC | 4,511 | $1.79M | 0.01% | +279+6.6% | Added |
| Omers Administration Corp | 4,517 | $1.80M | 0.01% | 00.0% | Unchanged |
| Burney Co | 4,582 | $1.82M | 0.06% | −301−6.2% | Reduced |
| E. Ohman J:or Asset Management AB | 4,584 | $1.82M | 0.04% | −1,116−19.6% | Reduced |
| Azzad Asset Management Inc | 4,591 | $1.83M | 0.18% | −29−0.6% | Reduced |
| Ameritas Investment Partners, Inc. | 4,776 | $1.90M | 0.06% | +4,776 | New |