Skip to main content

Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
852
+55 vs. Q3 2025
Shares held
132.8M
+3.06M (+2.4%) vs. Q3 2025
Total value
$52.7B
−$6.43B (−10.9%) vs. Q3 2025
New holders
172
290 more added
Sold out
117
291 more reduced

26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 852 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ4 2025: $52.7B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding ALNY in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Proffitt & Goodson Inc23$9.15K0.00%−1−4.2%Reduced
TD Capital Management LLC23$9.15K0.00%00.0%Unchanged
Estate Planners Group, LLC23$9.15K0.00%+23New
Salomon & Ludwin, LLC23$9.15K0.00%−37−61.7%Reduced
UMA Financial Services, Inc.24$9.54K0.00%−7−22.6%Reduced
Private Trust Co NA28$11.1K0.00%−547−95.1%Reduced
Swiss Re Ltd30$11.9K0.00%+30New
FWL Investment Management, LLC31$12.3K0.00%00.0%Unchanged
WPG Advisers, LLC31$12.3K0.01%00.0%Unchanged
Dogwood Wealth Management LLC31$12.3K0.01%+11+55.0%Added
Godsey & Gibb Associates32$12.7K0.00%+4+14.3%Added
Avion Wealth33$13.0K0.00%−4−10.8%Reduced
Sachetta, LLC33$13.1K0.01%−40−54.8%Reduced
SJS Investment Consulting Inc.35$13.9K0.00%+33+1,650.0%Added
SOA Wealth Advisors, LLC.36$14.3K0.00%00.0%Unchanged
Bogart Wealth, LLC36$14.3K0.00%+1+2.9%Added
Bell Investment Advisors, Inc36$14.3K0.00%00.0%Unchanged
Cape Investment Advisory, Inc.39$15.5K0.00%−69−63.9%Reduced
Millstone Evans Group, LLC40$15.9K0.01%00.0%Unchanged
Aventura Private Wealth, LLC40$15.9K0.01%00.0%Unchanged
MidFirst Bank541$16.3K0.00%+541New
Private Wealth Asset Management, LLC42$16.7K0.00%00.0%Unchanged
JFS Wealth Advisors, LLC45$17.9K0.00%+10+28.6%Added
Pinnacle Wealth Planning Services, Inc.49$19.3K0.00%+49New
Peoples Financial Services Corp.50$19.9K0.01%00.0%Unchanged
Piscataqua Savings Bank50$19.9K0.01%00.0%Unchanged
Generali Asset Management SPA SGR50$19.9K0.00%−3,184−98.5%Reduced
St. Johns Investment Management Company, LLC50$19.9K0.01%00.0%Unchanged
Rachor Investment Advisory Services, LLC51$20.3K0.01%+51New
Kemnay Advisory Services Inc.52$20.7K0.00%+52New
Sound Income Strategies, LLC61$21.9K0.00%+61New
CVA Family Office, LLC59$23.5K0.00%−3−4.8%Reduced
Global Trust Asset Management, LLC60$23.9K0.01%00.0%Unchanged
Truvestments Capital LLC60$23.9K0.00%+3+5.3%Added
Root Financial Partners, LLC62$24.7K0.00%+8+14.8%Added
Private Wealth Management Group, LLC62$24.7K0.01%00.0%Unchanged
Covestor Ltd63$25.0K0.01%−209−76.8%Reduced
MV Capital Management, Inc.63$25.1K0.00%−1−1.6%Reduced
HM Payson & Co68$27.0K0.00%+68New
Whittier Trust Co69$28.0K0.00%00.0%Unchanged
TFC Financial Management72$28.6K0.00%−2−2.7%Reduced
Golden State Wealth Management, LLC72$28.6K0.00%+36+100.0%Added
ORG Partners LLC73$29.0K0.01%−7−8.8%Reduced
Hilltop National Bank80$31.8K0.01%−11−12.1%Reduced
Cornerstone Planning Group LLC95$33.2K0.01%−397−80.7%Reduced
Whittier Trust Co of Nevada Inc82$33.3K0.00%−33−28.7%Reduced
Manchester Capital Management LLC84$33.4K0.00%+72+600.0%Added
Quent Capital, LLC94$37.4K0.00%+9+10.6%Added
Westside Investment Management, Inc.96$38.4K0.01%00.0%Unchanged
Elequin Capital LP97$38.6K0.01%+97New
Parkside Financial Bank & Trust97$38.6K0.00%−82−45.8%Reduced
Colonial Trust Co99$39.4K0.01%+61+160.5%Added
Hartford Financial Management Inc.100$39.8K0.01%00.0%Unchanged
Huntington National Bank102$40.6K0.00%+1+1.0%Added
Keating Financial Advisory Services, Inc.104$41.4K0.01%+104New
Leonteq Securities AG105$41.8K0.00%+102+3,400.0%Added
Eastern Bank105$41.8K0.00%+105New
Titan Wealth (CI) Ltd105$41.8K0.02%+105New
Activest Wealth Management108$42.9K0.01%+107+10,700.0%Added
SHP Wealth Management109$43.2K0.00%+109New
Harbour Investments, Inc.116$46.1K0.00%−11−8.7%Reduced
Basecamp Wealth Advisors LLC123$48.8K0.01%+123New
Rossby Financial, LCC124$49.3K0.02%+12+10.7%Added
Fideuram Asset Management (Ireland) dac122$49.8K0.00%+122New
Park Place Capital Corp126$50.1K0.01%00.0%Unchanged
Fifth Third Bancorp127$50.5K0.00%+70+122.8%Added
Brown, Lisle/Cummings, Inc.132$52.5K0.01%00.0%Unchanged
Stephenson National Bank & Trust135$53.7K0.02%−50−27.0%Reduced
Itau Unibanco Holding S.A.141$56.1K0.00%−27−16.1%Reduced
Quarry LP144$57.3K0.01%+123+585.7%Added
Clearstead Advisors, LLC147$58.5K0.00%−617−80.8%Reduced
SBI Securities Co., Ltd.147$58.5K0.00%+84+133.3%Added
Zions Bancorporation, National Association147$58.5K0.00%+138+1,533.3%Added
CoreCap Advisors, LLC152$60.4K0.00%−228−60.0%Reduced
Meeder Asset Management Inc154$61.2K0.00%+125+431.0%Added
True Wealth Design, LLC155$61.5K0.02%−73−32.0%Reduced
Reflection Asset Management159$63.2K0.04%+159New
Capital Advisors, Ltd. LLC162$64.0K0.01%00.0%Unchanged
First Horizon Corp163$64.8K0.00%+28+20.7%Added
Prestige Wealth Management Group LLC173$68.8K0.01%−11−6.0%Reduced
Evelyn Partners Investment Management LLP175$69.6K0.00%00.0%Unchanged
Brown Brothers Harriman & Co180$71.6K0.00%+7+4.0%Added
Rakuten Securities, Inc.189$75.2K0.02%+185+4,625.0%Added
LRI Investments, LLC192$76.2K0.01%+2+1.1%Added
Massmutual Trust Co FSB194$77.1K0.00%−3−1.5%Reduced
Concord Wealth Partners200$79.5K0.01%00.0%Unchanged
Spire Wealth Management202$80.3K0.00%−5−2.4%Reduced
Clear Street Markets LLC202$80.3K0.01%+202New
Bessemer Group Inc227$90.0K0.00%+5+2.3%Added
Atlantic Union Bankshares Corp231$91.9K0.00%+40+20.9%Added
Torren Management, LLC235$93.4K0.05%+235New
Larson Financial Group LLC241$95.8K0.00%−59−19.7%Reduced
Greenline Wealth Management LLC242$96.1K0.10%+242New
Munich Reinsurance Co Stock Corp in Munich275$109.2K0.00%+275New
Ronald Blue Trust, Inc.284$112.9K0.00%−65−18.6%Reduced
Havemeyer Place LP298$118.5K0.02%+298New
TD Waterhouse Canada Inc.330$131.2K0.00%00.0%Unchanged
E Fund Management (Hong Kong) Co., Ltd.389$131.9K0.06%+389New
Globeflex Capital L P335$133.2K0.02%+335New
Quantbot Technologies LP350$139.2K0.00%−825−70.2%Reduced