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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
852
+55 vs. Q3 2025
Shares held
132.8M
+3.06M (+2.4%) vs. Q3 2025
Total value
$52.7B
−$6.43B (−10.9%) vs. Q3 2025
New holders
172
290 more added
Sold out
117
291 more reduced

26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 852 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ4 2025: $52.7B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding ALNY in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
DeepCurrents Investment Group LLC0$00.00%−1,243−100.0%Sold out
Semanteon Capital Management, LP0$00.00%−1,232−100.0%Sold out
HBK Investments L P0$00.00%−1,231−100.0%Sold out
BlueCrest Capital Management Ltd0$00.00%−1,231−100.0%Sold out
Ground Swell Capital, LLC0$00.00%−1,111−100.0%Sold out
NorthRock Partners, LLC0$00.00%−1,094−100.0%Sold out
SIH Partners, LLLP0$00.00%−1,020−100.0%Sold out
Virtue Capital Management, LLC0$00.00%−4,121−100.0%Sold out
Yeomans Consulting Group, Inc.0$00.00%−984−100.0%Sold out
Peregrine Capital Management LLC0$00.00%−832−100.0%Sold out
Weiss Asset Management LP0$00.00%−795−100.0%Sold out
Requisite Capital Management, LLC0$00.00%−776−100.0%Sold out
Compass Capital Corp0$00.00%−800−100.0%Sold out
Baader Bank INC0$00.00%−760−100.0%Sold out
Kera Capital Partners, Inc.0$00.00%−706−100.0%Sold out
Polen Capital Management LLC0$00.00%−693−100.0%Sold out
Retireful, LLC0$00.00%−662−100.0%Sold out
Moran Wealth Management, LLC0$00.00%−625−100.0%Sold out
QTR Family Wealth, LLC0$00.00%−609−100.0%Sold out
Consolidated Portfolio Review Corp0$00.00%−601−100.0%Sold out
Humankind Investments LLC0$00.00%−600−100.0%Sold out
Beacon Investment Advisory Services, Inc.0$00.00%−585−100.0%Sold out
Charter Research & Investment Group, Inc.0$00.00%−585−100.0%Sold out
Stevens Capital Management LP0$00.00%−565−100.0%Sold out
Fukoku Mutual Life Insurance Co0$00.00%−551−100.0%Sold out
Capital International Investors0$00.00%−550−100.0%Sold out
Armis Advisers, LLC0$00.00%−560−100.0%Sold out
Fiduciary Alliance LLC0$00.00%−533−100.0%Sold out
Kestra Private Wealth Services, LLC0$00.00%−504−100.0%Sold out
Alliance Wealth Advisors, LLC0$00.00%−504−100.0%Sold out
Headinvest, LLC0$00.00%−500−100.0%Sold out
Longboard Asset Management, LP0$00.00%−500−100.0%Sold out
NWF Advisory Services Inc.0$00.00%−498−100.0%Sold out
TABR Capital Management, LLC0$00.00%−504−100.0%Sold out
MASTERINVEST Kapitalanlage GmbH0$00.00%−494−100.0%Sold out
Proficio Capital Partners LLC0$00.00%−488−100.0%Sold out
Telos Capital Management, Inc.0$00.00%−483−100.0%Sold out
Reuter James Wealth Management, LLC0$00.00%−483−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−476−100.0%Sold out
Arvest Bank Trust Division0$00.00%−472−100.0%Sold out
Riversedge Advisors, LLC0$00.00%−471−100.0%Sold out
Camden Capital, LLC0$00.00%−468−100.0%Sold out
Allegiance Financial Group Advisory Services LLC0$00.00%−462−100.0%Sold out
Advisor OS, LLC0$00.00%−461−100.0%Sold out
Dorsey & Whitney Trust CO LLC0$00.00%−460−100.0%Sold out
Bank Hapoalim BM0$00.00%−455−100.0%Sold out
KRS Capital Management, LLC0$00.00%−450−100.0%Sold out
Insigneo Advisory Services, LLC0$00.00%−449−100.0%Sold out
Ritholtz Wealth Management0$00.00%−447−100.0%Sold out
Summit Wealth Group LLC0$00.00%−643−100.0%Sold out
Icon Wealth Advisors, LLC0$00.00%−422−100.0%Sold out
Edmond de Rothschild Holding S.A.0$00.00%−188−100.0%Sold out
Ameritas Advisory Services, LLC0$00.00%−116−100.0%Sold out
Newbridge Financial Services Group, Inc.0$00.00%−85−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−78−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−63−100.0%Sold out
JPL Wealth Management, LLC0$00.00%−46−100.0%Sold out
Painted Porch Advisors LLC0$00.00%−32−100.0%Sold out
Palisade Asset Management, LLC0$00.00%−31−100.0%Sold out
Halbert Hargrove Global Advisors, LLC0$00.00%−23−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−20−100.0%Sold out
Evergreen Private Wealth LLC0$00.00%−17−100.0%Sold out
Mather Group, LLC.0$00.00%−14−100.0%Sold out
Marquette Asset Management, LLC0$00.00%−14−100.0%Sold out
Tortoise Investment Management, LLC0$00.00%−9−100.0%Sold out
Cloud Capital Management, LLC0$00.00%−10−100.0%Sold out
Clear Investment Research, LLC0$00.00%−8−100.0%Sold out
Logan Capital Management Inc0$00.00%−2−100.0%Sold out
Rise Advisors, LLC0$00.00%−1−100.0%Sold out
AXA Investment Managers S.A.––––Not filed
EFG Asset Management (North America) Corp.––––Not filed
Aware Super Pty Ltd as trustee of Aware Super––––Not filed
EFG Asset Management (Americas) Corp.––––Not filed
Wolverine Trading, LLC––––Not filed
Thematics Asset Management––––Not filed
CIBC Bancorp USA Inc.––––Not filed
Shell Asset Management Co––––Not filed
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Cubist Systematic Strategies, LLC––––Not filed
Wetherby Asset Management Inc––––Not filed
Full Sail Capital, LLC––––Not filed
Point72 Europe (London) LLP––––Not filed
Pinebridge Investments, L.P.––––Not filed
Point72 Hong Kong Ltd––––Not filed
First Affirmative Financial Network––––Not filed
Stonegate Investment Group, LLC––––Not filed
Gries Financial LLC––––Not filed
Glenmede Investment Management, LP––––Not filed
Point72 (DIFC) Ltd––––Not filed
Abich Financial Wealth Management LLC––––Not filed
Hemington Wealth Management––––Not filed
Guerra Advisors Inc––––Not filed
WFA Asset Management Corp––––Not filed
FSA Wealth Management LLC––––Not filed
Binnacle Investments Inc––––Not filed