Alnylam Pharmaceuticals, Inc.
ALNY- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001178670
No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Alnylam Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 823
- +178 vs. Q2 2025
- Shares held
- 129.9M
- −193.8K (−0.1%) vs. Q2 2025
- Total value
- $59.2B
- +$16.8B (+39.6%) vs. Q2 2025
- New holders
- 225
- 283 more added
- Sold out
- 47
- 223 more reduced
8 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 794 | $40.1B |
| Q1 2026 | 793 | $43.4B |
| Q4 2025 | 852 | $52.7B |
| Q3 2025 | 823 | $59.2B |
| Q2 2025 | 653 | $43.1B |
| Q1 2025 | 625 | $34.8B |
| Q4 2024 | 594 | $30.1B |
| Q3 2024 | 569 | $34.1B |
| Q2 2024 | 525 | $29.1B |
| Q1 2024 | 499 | $17.2B |
| Q4 2023 | 501 | $22.4B |
| Q3 2023 | 454 | $20.9B |
| Q2 2023 | 477 | $22.5B |
| Q1 2023 | 478 | $24.0B |
| Q4 2022 | 489 | $28.4B |
| Q3 2022 | 497 | $26.7B |
| Q2 2022 | 424 | $16.6B |
| Q1 2022 | 443 | $18.6B |
| Q4 2021 | 435 | $19.0B |
| Q3 2021 | 407 | $21.1B |
| Q2 2021 | 401 | $19.0B |
| Q1 2021 | 391 | $15.4B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sumitomo Mitsui DS Asset Management Company, Ltd | 15,826 | $7.22M | 0.06% | +1,018+6.9% | Added |
| Quantessence Capital LLC | 15,874 | $7.24M | 2.29% | +15,874 | New |
| Twin Tree Management, LP | 16,005 | $7.30M | 0.34% | +16,005 | New |
| EFG Asset Management (North America) Corp. | 16,335 | $7.44M | 0.96% | −4,827−22.8% | Reduced |
| Jefferies Financial Group Inc. | 16,542 | $7.54M | 0.07% | +8,200+98.3% | Added |
| Nissay Asset Management Corp | 16,575 | $7.56M | 0.04% | +287+1.8% | Added |
| Capital Group Investment Management Pte. Ltd. | 16,863 | $7.69M | 1.29% | −875−4.9% | Reduced |
| Verition Fund Management LLC | 17,033 | $7.77M | 0.04% | +11,330+198.7% | Added |
| Rafferty Asset Management, LLC | 17,151 | $7.82M | 0.03% | −15,045−46.7% | Reduced |
| Entropy Technologies, LP | 17,181 | $7.83M | 0.59% | +16,081+1,461.9% | Added |
| Silvant Capital Management LLC | 17,676 | $8.06M | 0.28% | −1,671−8.6% | Reduced |
| Caisse de Depot Et Placement du Quebec | 17,826 | $8.13M | 0.01% | −2,218−11.1% | Reduced |
| Elo Mutual Pension Insurance Co | 17,865 | $8.15M | 0.13% | +3,738+26.5% | Added |
| British Columbia Investment Management Corp | 18,739 | $8.54M | 0.05% | −1,732−8.5% | Reduced |
| Acadian Asset Management LLC | 19,083 | $8.70M | 0.02% | +11,364+147.2% | Added |
| Quantinno Capital Management LP | 19,265 | $8.79M | 0.02% | +5,801+43.1% | Added |
| MML Investors Services, LLC | 19,678 | $8.97M | 0.02% | +1,840+10.3% | Added |
| Police & Firemen's Retirement System of New Jersey | 20,093 | $9.16M | 0.07% | +1,130+6.0% | Added |
| Stifel Financial Corp | 20,295 | $9.25M | 0.01% | +6,595+48.1% | Added |
| Utah Retirement Systems | 20,599 | $9.39M | 0.09% | −371−1.8% | Reduced |
| Andra AP-fonden | 20,700 | $9.44M | 0.12% | +13,800+200.0% | Added |
| Ilmarinen Mutual Pension Insurance Co | 21,000 | $9.58M | 0.07% | 00.0% | Unchanged |
| Toronto Dominion Bank | 21,227 | $9.68M | 0.02% | −2,404−10.2% | Reduced |
| Swiss Life Asset Management Ltd | 21,521 | $9.81M | 0.05% | −2,268−9.5% | Reduced |
| Natixis Advisors, L.P. | 21,682 | $9.89M | 0.01% | +11,573+114.5% | Added |
| Atika Capital Management LLC | 22,206 | $10.1M | 0.86% | −5,494−19.8% | Reduced |
| Banco Bilbao Vizcaya Argentaria, S.A. | 22,235 | $10.1M | 0.08% | −16−0.1% | Reduced |
| Walleye Capital LLC | 22,345 | $10.2M | 0.08% | −16,370−42.3% | Reduced |
| AMF Pensionsforsakring AB | 22,558 | $10.3M | 0.07% | −9,979−30.7% | Reduced |
| China Universal Asset Management Co., Ltd. | 22,787 | $10.4M | 0.86% | −5,030−18.1% | Reduced |
| Creative Planning | 22,862 | $10.4M | 0.01% | +7,282+46.7% | Added |
| Eagle Health Investments LP | 23,686 | $10.8M | 2.84% | −22,400−48.6% | Reduced |
| Kornitzer Capital Management Inc | 23,689 | $10.8M | 0.22% | +525+2.3% | Added |
| Advisor Group Holdings, Inc. | 24,938 | $11.3M | 0.02% | +21,151+558.5% | Added |
| Mediolanum International Funds Ltd | 25,451 | $11.4M | 0.12% | +25,451 | New |
| IFM Investors Pty Ltd | 26,041 | $11.6M | 0.10% | +683+2.7% | Added |
| Erste Asset Management GmbH | 26,010 | $11.6M | 0.11% | −3,800−12.7% | Reduced |
| Xponance, Inc. | 26,152 | $11.9M | 0.09% | +1,135+4.5% | Added |
| Mariner, LLC | 26,332 | $12.0M | 0.02% | +11,259+74.7% | Added |
| USS Investment Management Ltd | 26,366 | $12.0M | 0.06% | 00.0% | Unchanged |
| Brown Advisory Inc | 26,592 | $12.1M | 0.02% | −2,879−9.8% | Reduced |
| Illinois Municipal Retirement Fund | 27,145 | $12.4M | 0.16% | +1,099+4.2% | Added |
| Cerity Partners LLC | 27,429 | $12.5M | 0.02% | +17,316+171.2% | Added |
| U.S. Capital Wealth Advisors, LLC | 27,544 | $12.6M | 0.34% | −24,483−47.1% | Reduced |
| Forsta Ap-Fonden | 27,900 | $12.7M | 0.08% | +1,500+5.7% | Added |
| STRS Ohio | 27,985 | $12.8M | 0.05% | −2,155−7.1% | Reduced |
| Gotham Asset Management, LLC | 28,135 | $12.8M | 0.06% | +10,348+58.2% | Added |
| Polymer Capital Management (HK) LTD | 28,900 | $13.2M | 1.83% | +31+0.1% | Added |
| CWM, LLC | 29,287 | $13.4M | 0.04% | +23,775+431.3% | Added |
| Zurich Insurance Group Ltd | 29,988 | $13.7M | 0.10% | −37,806−55.8% | Reduced |
| Fjarde Ap-Fonden /Fourth Swedish National Pension Fund | 30,215 | $13.8M | 0.12% | +200+0.7% | Added |
| ExodusPoint Capital Management, LP | 30,823 | $14.1M | 0.20% | +30,823 | New |
| SG Americas Securities, LLC | 31,850 | $14.5M | 0.05% | +31,850 | New |
| Rhenman & Partners Asset Management AB | 31,875 | $14.5M | 1.61% | −19,322−37.7% | Reduced |
| Antipodes Partners Ltd | 31,956 | $14.6M | 0.33% | −90,848−74.0% | Reduced |
| Palo Alto Investors LP | 32,320 | $14.7M | 2.73% | −43,215−57.2% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 32,369 | $14.8M | 0.04% | +967+3.1% | Added |
| Teachers Retirement System of the State of Kentucky | 32,818 | $15.0M | 0.11% | −400−1.2% | Reduced |
| AIA Group Ltd | 33,313 | $15.2M | 0.27% | +3,081+10.2% | Added |
| Teacher Retirement System of Texas | 33,642 | $15.3M | 0.06% | −2,766−7.6% | Reduced |
| Bridgewater Associates, LP | 33,911 | $15.5M | 0.06% | +33,911 | New |
| Voleon Capital Management LP | 33,965 | $15.5M | 0.38% | +32,609+2,404.8% | Added |
| Rosenblum Silverman Sutton S F Inc | 34,002 | $15.5M | 3.54% | −390−1.1% | Reduced |
| DnB Asset Management AS | 34,268 | $15.6M | 0.06% | +6,805+24.8% | Added |
| Artia Global Partners LP | 34,570 | $15.8M | 2.77% | +13,600+64.9% | Added |
| Jump Financial, LLC | 34,877 | $15.9M | 0.20% | +17,485+100.5% | Added |
| Parnassus Investments | 37,014 | $16.9M | 0.04% | −398−1.1% | Reduced |
| Oddo BHF Asset Management SAS | 37,927 | $17.3M | 0.66% | +1,987+5.5% | Added |
| Investment Management Corp of Ontario | 37,958 | $17.3M | 0.26% | +6,437+20.4% | Added |
| Arizona State Retirement System | 38,512 | $17.6M | 0.09% | +584+1.5% | Added |
| Public Employees Retirement System of Ohio | 38,994 | $17.8M | 0.06% | +242+0.6% | Added |
| Bronte Capital Management Pty Ltd. | 34,974 | $17.8M | 1.61% | +34,974 | New |
| CI Private Wealth, LLC | 39,392 | $18.0M | 0.03% | −2,760−6.5% | Reduced |
| Groupama Asset Managment | 32,082 | $18.6M | 0.27% | −16,303−33.7% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 40,944 | $18.7M | 0.04% | +10,193+33.1% | Added |
| Van Eck Associates Corp | 41,133 | $18.8M | 0.02% | −13,427−24.6% | Reduced |
| Resona Asset Management Co.,Ltd. | 41,497 | $18.9M | 0.09% | −2,203−5.0% | Reduced |
| Lansforsakringar Fondforvaltning AB (publ) | 42,404 | $19.3M | 0.10% | +2,173+5.4% | Added |
| Alliancebernstein L.P. | 43,776 | $20.0M | 0.01% | −23,355−34.8% | Reduced |
| Engineers Gate Manager LP | 43,849 | $20.0M | 0.23% | +11,219+34.4% | Added |
| State of New Jersey Common Pension Fund D | 45,532 | $20.8M | 0.08% | +1,673+3.8% | Added |
| LPL Financial LLC | 48,480 | $22.1M | 0.01% | +18,141+59.8% | Added |
| KLP Kapitalforvaltning AS | 48,800 | $22.3M | 0.09% | −300−0.6% | Reduced |
| Quadrature Capital Ltd | 48,920 | $22.3M | 0.26% | +47,033+2,492.5% | Added |
| Fiera Capital Corp | 53,804 | $24.5M | 0.08% | +26,061+93.9% | Added |
| Casdin Capital, LLC | 55,000 | $25.1M | 2.09% | −26,500−32.5% | Reduced |
| Treasurer of the State of North Carolina | 56,123 | $25.6M | 0.08% | −2,181−3.7% | Reduced |
| Danske Bank A/S | 57,407 | $26.2M | 0.07% | +2,400+4.4% | Added |
| Integral Health Asset Management, LLC | 60,000 | $27.4M | 1.99% | +5,000+9.1% | Added |
| Citigroup Inc | 60,866 | $27.8M | 0.02% | −187,372−75.5% | Reduced |
| Driehaus Capital Management LLC | 61,379 | $28.0M | 0.20% | −18,335−23.0% | Reduced |
| AXA Investment Managers S.A. | 61,663 | $28.1M | 0.08% | +61,663 | New |
| Ieq Capital, LLC | 62,177 | $28.4M | 0.09% | +56,055+915.6% | Added |
| Panagora Asset Management Inc | 62,354 | $28.4M | 0.11% | −30,145−32.6% | Reduced |
| Swedbank AB | 63,578 | $29.0M | 0.03% | −737−1.1% | Reduced |
| New York State Common Retirement Fund | 64,424 | $29.4M | 0.04% | +1,152+1.8% | Added |
| Lord, Abbett & Co. LLC | 67,220 | $30.7M | 0.09% | +67,220 | New |
| Manufacturers Life Insurance Company, The | 67,672 | $30.9M | 0.03% | −19,168−22.1% | Reduced |
| Ensign Peak Advisors, Inc | 67,733 | $30.9M | 0.05% | −32,476−32.4% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 67,935 | $31.0M | 0.47% | −77,065−53.1% | Reduced |