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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
823
+178 vs. Q2 2025
Shares held
129.9M
−193.8K (−0.1%) vs. Q2 2025
Total value
$59.2B
+$16.8B (+39.6%) vs. Q2 2025
New holders
225
283 more added
Sold out
47
223 more reduced

8 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 823 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ3 2025: $59.2B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q2 2025.

Institutions holding ALNY in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Whitebox Advisors LLC2,100$957.6K0.02%+2,100New
United Capital Financial Advisers, LLC2,145$978.1K0.01%+570+36.2%Added
Ethic Inc.2,184$996.0K0.02%+8+0.4%Added
UniSuper Management Pty Ltd2,200$1.00M0.01%00.0%Unchanged
Anchor Investment Management, LLC2,249$1.03M0.08%+2,049+1,024.5%Added
Persistent Asset Partners Ltd2,252$1.03M0.74%+2,252New
Nixon Peabody Trust Co2,347$1.07M0.08%+10+0.4%Added
QRG Capital Management, Inc.2,435$1.11M0.01%+299+14.0%Added
Principal Securities, Inc.2,438$1.11M0.02%+724+42.2%Added
Horizon Kinetics Asset Management LLC2,480$1.13M0.01%−279−10.1%Reduced
Vestcor Inc2,527$1.15M0.03%−309−10.9%Reduced
NEOS Investment Management LLC2,563$1.17M0.01%−2,738−51.7%Reduced
Tema ETFs LLC2,563$1.17M0.10%−2,738−51.7%Reduced
Kovitz Investment Group Partners, LLC2,607$1.19M0.00%+257+10.9%Added
Y-Intercept (Hong Kong) Ltd2,614$1.19M0.03%+2,614New
Everhart Financial Group, Inc.2,630$1.20M0.12%+437+19.9%Added
Central Pacific Bank - Trust Division2,635$1.20M0.15%−383−12.7%Reduced
Regal Investment Advisors LLC2,702$1.23M0.08%−204−7.0%Reduced
FORA Capital, LLC2,719$1.24M0.22%+2,719New
Western Financial Corp2,724$1.24M0.54%+2,724New
Park Avenue Securities LLC2,731$1.25M0.01%+646+31.0%Added
Greenleaf Trust2,735$1.25M0.01%+5+0.2%Added
Shepherd Financial Partners LLC2,736$1.25M0.12%00.0%Unchanged
Wiley Bros.-Aintree Capital, LLC2,743$1.25M0.01%+1,213+79.3%Added
Callan Family Office, LLC2,756$1.26M0.04%−175−6.0%Reduced
RSM US Wealth Management LLC2,764$1.26M0.02%−1,639−37.2%Reduced
Shell Asset Management Co2,779$1.27M0.13%−4,478−61.7%Reduced
Vontobel Holding Ltd.2,782$1.27M0.00%−135−4.6%Reduced
GF Fund Management Co. Ltd.2,797$1.28M0.02%−505−15.3%Reduced
Fig Financial Advisory Services Inc2,812$1.28M0.80%+2,812New
Sterling Capital Management LLC2,827$1.29M0.02%−9,262−76.6%Reduced
Generali Investments CEE, investicni spolecnost, a.s.2,900$1.32M0.10%00.0%Unchanged
Everence Capital Management Inc2,970$1.35M0.08%00.0%Unchanged
Graham Capital Management, L.P.3,015$1.37M0.05%−135−4.3%Reduced
Grandfield & Dodd, LLC3,120$1.42M0.08%+68+2.2%Added
Orion Capital Management LLC3,140$1.43M0.50%−100−3.1%Reduced
Sanders Morris Harris LLC3,150$1.44M0.19%+3,150New
Sumitomo Life Insurance Co3,167$1.44M0.04%+1,049+49.5%Added
Cambridge Investment Research Advisors, Inc.3,180$1.45M0.00%+1,796+129.8%Added
Kennedy Capital Management, Inc.3,220$1.47M0.03%+1,552+93.0%Added
Generali Asset Management SPA SGR3,234$1.47M0.03%+3,184+6,368.0%Added
Hall Laurie J Trustee3,250$1.48M0.48%00.0%Unchanged
Sectoral Asset Management Inc3,273$1.49M0.92%−50−1.5%Reduced
Kentucky Retirement Systems Insurance Trust Fund3,285$1.50M0.10%−218−6.2%Reduced
Spectrum Planning & Advisory Services Inc.3,350$1.53M0.86%−9−0.3%Reduced
Oxford Asset Management LLP3,350$1.53M0.50%+882+35.7%Added
Summit Trail Advisors, LLC3,435$1.57M0.02%+626+22.3%Added
Bamco Inc3,500$1.60M0.00%+3,500New
Lighthouse Investment Partners, LLC3,500$1.60M0.06%+3,500New
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main3,500$1.60M0.00%+3,500New
Inceptionr LLC3,519$1.60M0.39%−1,057−23.1%Reduced
Profund Advisors LLC3,536$1.61M0.05%−2,882−44.9%Reduced
Krilogy Financial LLC3,822$1.66M0.06%+3,822New
Brandywine Managers, LLC3,718$1.70M1.63%−500−11.9%Reduced
Scientech Research LLC3,872$1.77M0.62%+3,872New
Values First Advisors, Inc.3,882$1.77M0.95%−65−1.6%Reduced
B. Metzler seel. Sohn & Co. AG3,913$1.78M0.02%+680+21.0%Added
Atlantic Trust, LLC3,994$1.82M0.31%−286−6.7%Reduced
Janney Montgomery Scott LLC4,055$1.85M0.00%+4,055New
Knollwood Investment Advisory, LLC4,059$1.85M0.17%−1,296−24.2%Reduced
Keybank National Association4,060$1.85M0.01%+1,303+47.3%Added
Polar Asset Management Partners Inc.4,104$1.87M0.04%−5,496−57.3%Reduced
Moore Capital Management, LP4,104$1.87M0.04%+4,104New
Shaolin Capital Management LLC4,104$1.87M0.09%+4,104New
Sona Asset Management (US) LLC4,104$1.87M0.07%+4,104New
AG2R la Mondiale Gestion D'Actifs5,825$1.90M0.10%00.0%Unchanged
Merit Financial Group, LLC4,232$1.93M0.02%+2,342+123.9%Added
Howland Capital Management LLC4,243$1.93M0.07%+243+6.1%Added
Empowered Funds, LLC4,285$1.95M0.02%+1,432+50.2%Added
Soros Fund Management LLCSuperinvestorSoros Fund Management4,295$1.96M0.03%+4,295New
Oppenheimer Asset Management Inc.4,300$1.96M0.02%+2,972+223.8%Added
Sequoia Financial Advisors, LLC4,306$1.96M0.01%+389+9.9%Added
Metis Global Partners, LLC4,311$1.97M0.05%−326−7.0%Reduced
Rockefeller Capital Management L.P.4,380$2.00M0.00%+4,380New
Pallas Capital Advisors LLC4,425$2.02M0.07%+1,855+72.2%Added
Tokio Marine Asset Management Co Ltd4,444$2.03M0.07%+4,444New
Omers Administration Corp4,517$2.06M0.01%00.0%Unchanged
Advisors Asset Management, Inc.4,522$2.06M0.03%−23−0.5%Reduced
Commerce Bank4,531$2.07M0.01%−5−0.1%Reduced
Aigen Investment Management, LP4,538$2.07M0.32%+4,538New
Highland Capital Management, LLC4,569$2.08M0.10%+4,569New
Allstate Corp4,571$2.08M0.05%+4,571New
Azzad Asset Management Inc4,620$2.11M0.21%+1,969+74.3%Added
Donoghue Forlines LLC4,627$2.11M0.65%+4,627New
ProShare Advisors LLC4,631$2.11M0.00%+390+9.2%Added
Integrated Wealth Concepts LLC4,636$2.11M0.02%+1,191+34.6%Added
CIBC Bancorp USA Inc.4,675$2.13M0.01%+4,675New
Banque Cantonale Vaudoise4,860$2.22M0.08%−883−15.4%Reduced
Plato Investment Management Ltd4,906$2.22M0.15%+793+19.3%Added
Burney Co4,883$2.23M0.07%−259−5.0%Reduced
Brighton Jones LLC4,941$2.25M0.05%+3,909+378.8%Added
Susquehanna Portfolio Strategies, LLC5,005$2.28M0.04%00.0%Unchanged
Buckingham Strategic Partners5,127$2.28M0.03%+4,317+533.0%Added
Gateway Investment Advisers LLC5,141$2.34M0.02%−748−12.7%Reduced
Atria Investments LLC5,194$2.37M0.03%+918+21.5%Added
Vident Advisory, LLC5,237$2.39M0.02%+1,312+33.4%Added
West Michigan Advisors, LLC5,396$2.46M0.59%+5,396New
Brinker Capital Investments, LLC5,398$2.46M0.02%+1,089+25.3%Added
Principal Financial Group Inc5,420$2.47M0.00%−45,114−89.3%Reduced
Mirabella Financial Services LLP5,447$2.48M0.22%+2,477+83.4%Added