Skip to main content

Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
823
+178 vs. Q2 2025
Shares held
129.9M
−193.8K (−0.1%) vs. Q2 2025
Total value
$59.2B
+$16.8B (+39.6%) vs. Q2 2025
New holders
225
283 more added
Sold out
47
223 more reduced

8 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 823 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ3 2025: $59.2B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q2 2025.

Institutions holding ALNY in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Asahi Life Asset Management Co., Ltd.1,043$475.6K0.26%−237−18.5%Reduced
Nichols & Pratt Advisers LLP1,043$475.6K0.03%00.0%Unchanged
Smartleaf Asset Management LLC1,077$481.9K0.03%+483+81.3%Added
EntryPoint Capital, LLC1,058$482.4K0.19%−492−31.7%Reduced
Wedmont Private Capital1,055$484.9K0.02%−706−40.1%Reduced
Capital Group Private Client Services, Inc.1,070$487.9K0.01%00.0%Unchanged
Rothschild Investment LLC1,078$491.6K0.03%+1,076+53,800.0%Added
Vestmark Advisory Solutions, Inc.1,085$494.8K0.01%−655−37.6%Reduced
NorthRock Partners, LLC1,094$498.9K0.01%+1,094New
Sivia Capital Partners, LLC1,096$499.8K0.14%+1,096New
Coastal Bridge Advisors, LLC1,097$500.2K0.04%+25+2.3%Added
Aaron Wealth Advisors1,109$505.7K0.03%+1,109New
Ground Swell Capital, LLC1,111$506.6K1.11%+1,111New
EverSource Wealth Advisors, LLC1,130$515.3K0.02%+693+158.6%Added
TB Alternative Assets Ltd.1,133$516.6K0.08%−126−10.0%Reduced
Mathes Company, Inc.1,155$527.0K0.19%00.0%Unchanged
Quantbot Technologies LP1,175$535.8K0.01%+1,175New
Perigon Wealth Management, LLC1,183$539.2K0.01%+1,183New
Hilltop Holdings Inc.1,189$542.2K0.03%+273+29.8%Added
Calamos Advisors LLC1,200$547.2K0.00%+1,200New
Crossmark Global Holdings, Inc.1,224$558.1K0.01%+180+17.2%Added
Cigna Investments Inc1,230$561.0K0.08%−15−1.2%Reduced
HBK Investments L P1,231$561.3K0.01%+1,231New
Capstone Investment Advisors, LLC1,231$561.3K0.00%+1,231New
BlueCrest Capital Management Ltd1,231$561.3K0.03%+1,231New
Semanteon Capital Management, LP1,232$561.8K0.70%+1,232New
Vinva Investment Management Ltd1,258$562.9K0.01%+1,258New
Essential Partners LLC1,236$563.6K0.19%+1,174+1,893.5%Added
DeepCurrents Investment Group LLC1,243$566.8K0.02%+1,243New
Crowley Wealth Management, Inc.1,250$570.0K0.45%00.0%Unchanged
Frank, Rimerman Advisors LLC1,251$570.5K0.04%+24+2.0%Added
Qsemble Capital Management, LP1,255$572.3K0.06%−275−18.0%Reduced
Wetherby Asset Management Inc1,266$577.3K0.02%+40+3.3%Added
Sagespring Wealth Partners, LLC1,287$587.0K0.01%+371+40.5%Added
Allworth Financial LP1,290$588.1K0.00%+599+86.7%Added
Quantedge Capital Pte Ltd1,300$592.8K0.32%+1,300New
North Star Asset Management Inc1,305$595.1K0.02%00.0%Unchanged
Convergence Investment Partners, LLC1,307$596.0K0.13%−952−42.1%Reduced
Abn Amro Investment Solutions1,310$597.4K0.01%00.0%Unchanged
Envestnet Portfolio Solutions, Inc.1,327$605.1K0.00%+163+14.0%Added
Winslow Capital Management, LLC1,335$608.8K0.00%−1,176,104−99.9%Reduced
Cubist Systematic Strategies, LLC1,352$616.4K0.01%+1,352New
Westpac Banking Corp1,355$617.9K0.04%00.0%Unchanged
Banque Pictet & Cie SA1,385$631.6K0.01%−6−0.4%Reduced
J.Safra Asset Management Corp1,395$636.1K0.04%+1,352+3,144.2%Added
Norden Group LLC1,411$643.4K0.07%+1,411New
Freestone Grove Partners LP1,412$643.9K0.00%+1,412New
Lecap Asset Management Ltd1,418$646.6K0.22%−567−28.6%Reduced
Private Advisory Group LLC1,419$647.1K0.06%+1,419New
Souders Financial Advisors1,423$648.9K0.08%+64+4.7%Added
Steward Partners Investment Advisory, LLC1,443$658.0K0.00%+86+6.3%Added
Sara-Bay Financial1,450$661.2K0.18%00.0%Unchanged
Virtus Investment Advisers, Inc.1,459$665.3K0.19%00.0%Unchanged
Fox Run Management, L.L.C.1,465$668.0K0.10%+202+16.0%Added
Qtron Investments LLC1,471$670.8K0.08%+1,471New
Point72 Asia (Singapore) Pte. Ltd.1,474$672.6K0.10%+656+80.2%Added
HB Wealth Management, LLC1,476$673.1K0.00%+607+69.9%Added
CTC Alternative Strategies, Ltd.1,496$682.2K1.14%+1,496New
High Net Worth Advisory Group LLC1,500$684.0K0.16%00.0%Unchanged
GWM Advisors LLC1,524$694.7K0.00%+820+116.5%Added
Tower Research Capital LLC (TRC)1,537$700.9K0.02%+1,473+2,301.6%Added
Fulton Bank, N.A.1,544$704.1K0.02%+123+8.7%Added
Orser Capital Management, LLC1,544$704.1K0.39%+1,544New
Forum Financial Management, LP1,556$709.5K0.01%00.0%Unchanged
Ossiam1,556$709.5K0.01%+201+14.8%Added
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,533$711.3K0.01%00.0%Unchanged
Diversified Trust Co1,570$715.9K0.01%+472+43.0%Added
S-Bank Fund Management Ltd1,593$726.4K0.10%−21−1.3%Reduced
Walleye Trading LLC1,595$727.3K0.01%+1,252+365.0%Added
NorthCrest Asset Manangement, LLC1,605$737.5K0.02%+1,605New
New York Life Investment Management LLC1,629$742.8K0.01%−474−22.5%Reduced
Steel Peak Wealth Management LLC1,635$745.4K0.03%−1,173−41.8%Reduced
GraniteShares Advisors LLC1,639$747.4K0.43%−260−13.7%Reduced
Sava Infond d.o.o.1,640$747.8K0.11%−540−24.8%Reduced
Coldstream Capital Management Inc1,640$747.8K0.01%+38+2.4%Added
Kestra Advisory Services, LLC1,645$750.1K0.00%+561+51.8%Added
iA Global Asset Management Inc.1,647$751.0K0.01%+1,647New
Yousif Capital Management, LLC1,647$751.0K0.01%+80+5.1%Added
R Squared Ltd1,660$757.0K0.33%+1,660New
Ballentine Partners, LLC1,661$757.4K0.01%+44+2.7%Added
Caerus Investment Advisors, LLC1,672$762.4K0.31%+1,672New
Emerald Advisers, LLC1,695$772.9K0.02%−246−12.7%Reduced
Fort Sheridan Advisors LLC1,701$775.7K0.10%00.0%Unchanged
Oppenheimer & Co Inc1,716$782.5K0.01%00.0%Unchanged
Nomura Holdings Inc1,726$787.1K0.00%+1,726New
Two Sigma Securities, LLC1,740$793.4K0.12%+1,740New
Financiere des Professionnels - Fonds d,investissement inc.1,804$822.6K0.05%+1,804New
Siemens Fonds Invest GmbH1,837$837.7K0.05%−6−0.3%Reduced
Meeder Advisory Services, Inc.1,889$861.4K0.04%+764+67.9%Added
Greenland Capital Management LP1,959$893.3K0.13%+959+95.9%Added
Fred Alger Management, LLC1,986$905.6K0.00%+1,986New
Signaturefd, LLC1,998$911.2K0.01%+92+4.8%Added
Security National Bank of So Dak2,000$912.0K0.46%00.0%Unchanged
CSS LLC2,010$916.6K0.05%+2,010New
Harvest Fund Management Co., Ltd2,021$920.0K0.04%+896+79.6%Added
Archford Capital Strategies, LLC2,024$922.9K0.11%+7+0.3%Added
Bannerman Wealth Management Group, LLC2,047$933.4K0.69%−117−5.4%Reduced
Pinkerton Retirement Specialists, LLC2,049$934.3K0.10%+2,049New
Exchange Traded Concepts, LLC2,073$945.3K0.01%−733−26.1%Reduced
Aristeia Capital LLC2,100$957.6K0.03%+2,100New