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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
653
+35 vs. Q1 2025
Shares held
132.1M
+2.77M (+2.1%) vs. Q1 2025
Total value
$43.1B
+$8.27B (+23.8%) vs. Q1 2025
New holders
98
262 more added
Sold out
63
214 more reduced

7 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 653 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ2 2025: $43.1B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding ALNY in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Mackenzie Financial Corp9,075$2.96M0.00%−410−4.3%Reduced
Amalgamated Bank9,468$3.09M0.02%+615+6.9%Added
Employees Retirement System of Texas9,474$3.09M0.03%+9,474New
Polar Asset Management Partners Inc.9,600$3.13M0.08%+9,600New
Cetera Investment Advisers9,888$3.22M0.01%+1,871+23.3%Added
Commonwealth Equity Services, LLC9,926$3.24M0.00%+1,455+17.2%Added
S&CO Inc10,050$3.28M0.21%00.0%Unchanged
Traynor Capital Management, Inc.10,205$3.29M0.23%+372+3.8%Added
Natixis Advisors, L.P.10,109$3.30M0.01%+10,109New
Cerity Partners LLC10,113$3.30M0.01%−4,529−30.9%Reduced
Silvercrest Asset Management Group LLC10,251$3.34M0.02%+430+4.4%Added
Blair William & Co10,592$3.45M0.01%−486−4.4%Reduced
Guggenheim Capital LLC10,649$3.47M0.03%−1,718−13.9%Reduced
Catalyst Funds Management Pty Ltd10,770$3.51M0.97%−8,430−43.9%Reduced
Cullen/Frost Bankers, Inc.10,795$3.52M0.04%+78+0.7%Added
Nordea Investment Management AB11,295$3.64M0.00%+1,060+10.4%Added
Mirae Asset Global ETFs Holdings Ltd.11,558$3.76M0.01%−2,395−17.2%Reduced
Assetmark, Inc11,543$3.76M0.01%+902+8.5%Added
Readystate Asset Management LP11,601$3.78M0.16%+11,601New
EFG Asset Management (Americas) Corp.11,615$3.79M0.70%−1,757−13.1%Reduced
Zacks Investment Management11,931$3.89M0.03%−10,331−46.4%Reduced
Wealthfront Advisers LLC12,084$3.94M0.01%+3,363+38.6%Added
Sterling Capital Management LLC12,089$3.94M0.06%−1,008−7.7%Reduced
Tredje AP-fonden12,202$3.98M0.03%−3,705−23.3%Reduced
Liontrust Investment Partners LLP12,769$4.16M0.06%−6,111−32.4%Reduced
Public Employees Retirement Association of Colorado12,841$4.19M0.02%−232−1.8%Reduced
Daiwa Securities Group Inc.12,941$4.22M0.02%+35+0.3%Added
Mirae Asset Securities (USA) Inc.13,034$4.25M0.19%+13,034New
Bank of Montreal13,111$4.28M0.00%+2,427+22.7%Added
The PNC Financial Services Group, Inc.13,170$4.29M0.00%+45+0.3%Added
JustInvest LLC13,390$4.37M0.05%+4,302+47.3%Added
Quantinno Capital Management LP13,464$4.39M0.02%+7,032+109.3%Added
Himension Fund13,486$4.40M0.34%−1,816−11.9%Reduced
Aware Super Pty Ltd as trustee of Aware Super13,665$4.46M0.07%00.0%Unchanged
Stifel Financial Corp13,700$4.47M0.00%+6,627+93.7%Added
OP Asset Management Ltd13,934$4.54M0.07%+255+1.9%Added
Elo Mutual Pension Insurance Co14,127$4.61M0.09%+3,222+29.5%Added
Sumitomo Mitsui DS Asset Management Company, Ltd14,808$4.83M0.04%+1,851+14.3%Added
J. Safra Sarasin Holding AG14,996$4.89M0.08%−1,439−8.8%Reduced
Mariner, LLC15,073$4.91M0.01%+190+1.3%Added
Hudson Bay Capital Management LP15,348$5.00M0.03%+15,348New
Creative Planning15,580$5.08M0.00%−519−3.2%Reduced
Mutual of America Capital Management LLC15,946$5.20M0.06%+2,302+16.9%Added
Nissay Asset Management Corp16,288$5.31M0.03%+74+0.5%Added
Jain Global LLC16,730$5.46M0.08%+10,509+168.9%Added
Jump Financial, LLC17,392$5.67M0.07%+1,675+10.7%Added
Jacobs Levy Equity Management, Inc17,674$5.76M0.02%−135,296−88.4%Reduced
Assenagon Asset Management S.A.17,686$5.77M0.01%+11,281+176.1%Added
Capital Group Investment Management Pte. Ltd.17,738$5.78M1.03%+388+2.2%Added
Gotham Asset Management, LLC17,787$5.80M0.03%+3,270+22.5%Added
MML Investors Services, LLC17,838$5.82M0.02%+4,911+38.0%Added
First Turn Management, LLC17,879$5.83M1.09%+17,879New
HRT Financial LP17,887$5.83M0.03%−37,286−67.6%Reduced
Comerica Bank18,617$6.07M0.02%+1,364+7.9%Added
Police & Firemen's Retirement System of New Jersey18,963$6.18M0.06%+212+1.1%Added
Boothbay Fund Management, LLC19,213$6.27M0.20%+9,123+90.4%Added
Silvant Capital Management LLC19,347$6.31M0.24%+3,152+19.5%Added
Point72 Europe (London) LLP19,934$6.50M0.33%+3,976+24.9%Added
Caisse de Depot Et Placement du Quebec20,044$6.54M0.01%−3,719−15.7%Reduced
British Columbia Investment Management Corp20,471$6.68M0.04%−4,195−17.0%Reduced
Trexquant Investment LP20,543$6.70M0.08%+20,543New
Artia Global Partners LP20,970$6.84M1.76%−7,630−26.7%Reduced
Utah Retirement Systems20,970$6.84M0.07%−355−1.7%Reduced
Ilmarinen Mutual Pension Insurance Co21,000$6.85M0.06%+21,000New
EFG Asset Management (North America) Corp.21,162$6.89M0.97%−3,529−14.3%Reduced
Banco Bilbao Vizcaya Argentaria, S.A.22,251$7.26M0.07%−512−2.2%Reduced
Jane Street Group, LLC22,856$7.45M0.01%−75,695−76.8%Reduced
Cinctive Capital Management LP22,868$7.46M0.42%−1,994−8.0%Reduced
Kornitzer Capital Management Inc23,164$7.55M0.15%+21,164+1,058.2%Added
Toronto Dominion Bank23,631$7.71M0.02%+4,246+21.9%Added
Swiss Life Asset Management Ltd23,789$7.76M0.05%+13,979+142.5%Added
Xponance, Inc.25,017$8.16M0.07%+1,860+8.0%Added
IFM Investors Pty Ltd25,358$8.27M0.08%+1,508+6.3%Added
Illinois Municipal Retirement Fund26,046$8.49M0.12%−36,619−58.4%Reduced
USS Investment Management Ltd26,366$8.59M0.05%00.0%Unchanged
Forsta Ap-Fonden26,400$8.61M0.06%+600+2.3%Added
DnB Asset Management AS27,463$8.96M0.04%+166+0.6%Added
Atika Capital Management LLC27,700$9.03M0.94%+27,700New
Fiera Capital Corp27,743$9.05M0.03%+10,531+61.2%Added
China Universal Asset Management Co., Ltd.27,817$9.07M0.85%−3,154−10.2%Reduced
Polymer Capital Management (HK) LTD28,869$9.41M1.47%+11,065+62.1%Added
Iron Triangle Partners LP29,339$9.57M1.51%−36,070−55.1%Reduced
Brown Advisory Inc29,471$9.61M0.01%−1,914−6.1%Reduced
Erste Asset Management GmbH29,810$9.62M0.08%+6,500+27.9%Added
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund30,015$9.79M0.09%+3,100+11.5%Added
STRS Ohio30,140$9.83M0.04%+1,323+4.6%Added
AIA Group Ltd30,232$9.86M0.21%+3,741+14.1%Added
LPL Financial LLC30,339$9.89M0.00%+9,660+46.7%Added
Zurcher Kantonalbank (Zurich Cantonalbank)30,751$10.0M0.02%−26,368−46.2%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.31,402$10.2M0.02%+15,569+98.3%Added
Investment Management Corp of Ontario31,521$10.3M0.15%+8,244+35.4%Added
Rafferty Asset Management, LLC32,196$10.5M0.03%−12,389−27.8%Reduced
AMF Pensionsforsakring AB32,537$10.6M0.07%+32,537New
Engineers Gate Manager LP32,630$10.6M0.13%+7,238+28.5%Added
Teachers Retirement System of the State of Kentucky33,218$10.8M0.09%+505+1.5%Added
Rosenblum Silverman Sutton S F Inc34,392$11.2M2.72%−240−0.7%Reduced
Canada Pension Plan Investment Board35,520$11.6M0.01%−25,012−41.3%Reduced
Oddo BHF Asset Management SAS35,940$11.7M0.45%+16,119+81.3%Added
Teacher Retirement System of Texas36,408$11.9M0.05%+1,123+3.2%Added
Parnassus Investments37,412$12.2M0.03%+37,412New