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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
443
+10 vs. Q4 2021
Shares held
114.0M
+1.95M (+1.7%) vs. Q4 2021
Total value
$18.6B
−$367.5M (−1.9%) vs. Q4 2021
New holders
68
154 more added
Sold out
58
149 more reduced

2 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 443 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ1 2022: $18.6B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q4 2021.

Institutions holding ALNY in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Nuveen Asset Management, LLC362,035$58.8M0.02%−228,509−38.7%Reduced
Charles Schwab Investment Management Inc372,623$60.8M0.02%+9,662+2.7%Added
Rockefeller Capital Management L.P.373,964$61.1M0.29%−12,296−3.2%Reduced
TD Asset Management Inc392,682$64.1M0.06%−3,791−1.0%Reduced
First Trust Advisors LP402,652$65.7M0.07%−104,444−20.6%Reduced
Swedbank AB438,356$71.6M0.13%+1,791+0.4%Added
Deep Track Capital, LP463,663$75.7M4.89%+463,663New
Mitsubishi UFJ Trust & Banking Corp468,452$76.5M0.18%−2,559−0.5%Reduced
Blackstone Group Inc.517,391$84.5M0.21%00.0%Unchanged
Swiss National Bank518,010$84.6M0.05%+66,300+14.7%Added
Janus Henderson Group PLC598,448$97.7M0.05%+97,115+19.4%Added
UBS Asset Management Americas Inc605,165$98.8M0.04%−35,545−5.5%Reduced
Bank of New York Mellon Corp638,868$104.3M0.02%+36,554+6.1%Added
Artal Group S.A.650,000$106.1M4.49%00.0%Unchanged
Pictet Asset Management SA660,940$107.9M0.12%+46,948+7.6%Added
Goldman Sachs Group Inc681,553$111.3M0.03%−5,142−0.7%Reduced
Legal & General Group Plc757,422$123.7M0.04%+77,852+11.5%Added
Northern Trust Corp763,340$124.6M0.02%−6,073−0.8%Reduced
Gilder Gagnon Howe & Co LLC791,224$129.2M1.19%−48,344−5.8%Reduced
Holocene Advisors, LP799,222$130.5M0.69%+76,483+10.6%Added
Morgan Stanley848,657$138.6M0.02%−217,032−20.4%Reduced
Loomis Sayles & Co L P868,748$141.9M0.19%−127,689−12.8%Reduced
Amundi874,950$142.0M0.10%+620,695+244.1%Added
Invesco Ltd.968,755$158.2M0.04%+78,665+8.8%Added
Casdin Capital, LLC1,000,000$163.3M7.32%00.0%Unchanged
Farallon Capital Management, L.L.C.1,023,873$167.2M0.92%−166,155−14.0%Reduced
American Century Companies Inc1,131,844$184.8M0.13%+129,270+12.9%Added
Bellevue Group AG1,229,563$200.8M2.33%−105,577−7.9%Reduced
Norges Bank1,295,087$211.5M0.05%+25,896+2.0%Added
Avoro Capital Advisors LLC1,300,000$212.3M3.88%+225,000+20.9%Added
Geode Capital Management, LLC1,570,283$256.0M0.03%+64,992+4.3%Added
RTW Investments, LP1,683,362$274.9M5.69%−292,517−14.8%Reduced
Manufacturers Life Insurance Company, The1,751,063$286.1M0.19%+48,393+2.8%Added
State Street Corp2,909,490$475.1M0.02%+59,101+2.1%Added
JPMorgan Chase & Co2,919,015$476.6M0.06%−53,070−1.8%Reduced
Dodge & Cox5,475,668$894.1M0.54%+44,600+0.8%Added
Capital World Investors5,999,674$979.7M0.17%+5,680,728+1,781.1%Added
Price T Rowe Associates Inc6,794,166$1.11B0.11%+258,798+4.0%Added
Wellington Management Group LLP7,034,487$1.15B0.20%+190,057+2.8%Added
BlackRock Inc.7,608,954$1.24B0.03%−62,448−0.8%Reduced
Baillie Gifford & Co10,139,729$1.66B1.16%−477,022−4.5%Reduced
Vanguard Group Inc10,829,144$1.77B0.04%+126,373+1.2%Added
FMR LLC16,045,316$2.62B0.21%−1,894,704−10.6%Reduced
Federated Hermes, Inc.0$00.00%−992,180−100.0%Sold out
Avidity Partners Management LP0$00.00%−370,000−100.0%Sold out
Assenagon Asset Management S.A.0$00.00%−174,443−100.0%Sold out
EcoR1 Capital, LLC0$00.00%−98,146−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−81,241−100.0%Sold out
Lord, Abbett & Co. LLC0$00.00%−42,000−100.0%Sold out
Logos Global Management LP0$00.00%−35,000−100.0%Sold out
PointState Capital LP0$00.00%−30,000−100.0%Sold out
Ghost Tree Capital, LLC0$00.00%−30,000−100.0%Sold out
Brookfield Asset Management Inc.0$00.00%−24,352−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−24,057−100.0%Sold out
Nomura Holdings Inc0$00.00%−22,403−100.0%Sold out
Integral Health Asset Management, LLC0$00.00%−20,000−100.0%Sold out
Varma Mutual Pension Insurance Co0$00.00%−20,000−100.0%Sold out
Goldstream Capital Management Ltd0$00.00%−18,096−100.0%Sold out
SG3 Management, LLC0$00.00%−17,000−100.0%Sold out
Cutler Group LP0$00.00%−11,582−100.0%Sold out
Metropolitan Life Insurance Co0$00.00%−7,891−100.0%Sold out
Cinctive Capital Management LP0$00.00%−6,990−100.0%Sold out
E. Ohman J:or Asset Management AB0$00.00%−6,400−100.0%Sold out
Alpine Global Management, LLC0$00.00%−6,334−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−5,745−100.0%Sold out
Maven Securities LTD0$00.00%−5,086−100.0%Sold out
PEAK6 Investments LLC0$00.00%−4,704−100.0%Sold out
Livingston Group Asset Management CO (operating as Southport Capital Management)0$00.00%−4,175−100.0%Sold out
Cresset Asset Management, LLC0$00.00%−3,852−100.0%Sold out
Walleye Capital LLC0$00.00%−3,772−100.0%Sold out
Davenport & Co LLC0$00.00%−3,705−100.0%Sold out
Advisors Asset Management, Inc.0$00.00%−3,644−100.0%Sold out
Walleye Trading LLC0$00.00%−3,305−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−3,134−100.0%Sold out
Agf Investments Inc.0$00.00%−2,882−100.0%Sold out
Pensionfund DSM Netherlands0$00.00%−2,000−100.0%Sold out
Engineers Gate Manager LP0$00.00%−1,990−100.0%Sold out
Parallax Volatility Advisers, L.P.0$00.00%−1,805−100.0%Sold out
NinePointTwo Capital0$00.00%−1,672−100.0%Sold out
Essex Savings Bank0$00.00%−1,652−100.0%Sold out
National Asset Management, Inc.0$00.00%−1,575−100.0%Sold out
Cetera Investment Advisers0$00.00%−1,217−100.0%Sold out
Coastline Trust Co0$00.00%−1,200−100.0%Sold out
GraniteShares Advisors LLC0$00.00%−595−100.0%Sold out
HM Payson & Co0$00.00%−218−100.0%Sold out
Vigilant Capital Management, LLC0$00.00%−200−100.0%Sold out
KRS Capital Management, LLC0$00.00%−200−100.0%Sold out
FSB Premier Wealth Management, Inc.0$00.00%−178−100.0%Sold out
Optiver Holding B.V.0$00.00%−124−100.0%Sold out
State of Wyoming0$00.00%−94−100.0%Sold out
Huntington National Bank0$00.00%−81−100.0%Sold out
Standard Family Office LLC0$00.00%−40−100.0%Sold out
SkyView Investment Advisors, LLC0$00.00%−509−100.0%Sold out
Signet Financial Management, LLC0$00.00%−18−100.0%Sold out
TSFG, LLC0$00.00%−17−100.0%Sold out
Snowden Capital Advisors LLC0$00.00%−22−100.0%Sold out
Lee Financial Co0$00.00%−7−100.0%Sold out
Column Capital Advisors, LLC0$00.00%−3−100.0%Sold out
Lenox Wealth Advisors, LLC0$00.00%−6−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−7−100.0%Sold out