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Alnylam Pharmaceuticals, Inc.

ALNY
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001178670

No open-market purchases or sales by Alnylam Pharmaceuticals, Inc. insiders were filed in the last 90 days; 794 institutions reported holding it in 13F filings for Q2 2026, worth $40.1B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Alnylam Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
435
+36 vs. Q3 2021
Shares held
112.1M
+547.7K (+0.5%) vs. Q3 2021
Total value
$19.0B
−$2.05B (−9.7%) vs. Q3 2021
New holders
77
156 more added
Sold out
41
132 more reduced

8 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ALNY on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 435 institutions
Q1 2021: 391 institutionsQ2 2021: 401 institutionsQ3 2021: 407 institutionsQ4 2021: 435 institutionsQ1 2022: 443 institutionsQ2 2022: 424 institutionsQ3 2022: 497 institutionsQ4 2022: 489 institutionsQ1 2023: 478 institutionsQ2 2023: 477 institutionsQ3 2023: 454 institutionsQ4 2023: 501 institutionsQ1 2024: 499 institutionsQ2 2024: 525 institutionsQ3 2024: 569 institutionsQ4 2024: 594 institutionsQ1 2025: 625 institutionsQ2 2025: 653 institutionsQ3 2025: 823 institutionsQ4 2025: 852 institutionsQ1 2026: 793 institutionsQ2 2026: 794 institutions
Value heldQ4 2021: $19.0B
Q1 2021: $15.4BQ2 2021: $19.0BQ3 2021: $21.1BQ4 2021: $19.0BQ1 2022: $18.6BQ2 2022: $16.6BQ3 2022: $26.7BQ4 2022: $28.4BQ1 2023: $24.0BQ2 2023: $22.5BQ3 2023: $20.9BQ4 2023: $22.4BQ1 2024: $17.2BQ2 2024: $29.1BQ3 2024: $34.1BQ4 2024: $30.1BQ1 2025: $34.8BQ2 2025: $43.1BQ3 2025: $59.2BQ4 2025: $52.7BQ1 2026: $43.4BQ2 2026: $40.1B
Institutions holding ALNY and their total value by quarter
QuarterHoldersValue
Q2 2026794$40.1B
Q1 2026793$43.4B
Q4 2025852$52.7B
Q3 2025823$59.2B
Q2 2025653$43.1B
Q1 2025625$34.8B
Q4 2024594$30.1B
Q3 2024569$34.1B
Q2 2024525$29.1B
Q1 2024499$17.2B
Q4 2023501$22.4B
Q3 2023454$20.9B
Q2 2023477$22.5B
Q1 2023478$24.0B
Q4 2022489$28.4B
Q3 2022497$26.7B
Q2 2022424$16.6B
Q1 2022443$18.6B
Q4 2021435$19.0B
Q3 2021407$21.1B
Q2 2021401$19.0B
Q1 2021391$15.4B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Alnylam Pharmaceuticals, Inc.; share changes are against Q3 2021.

Institutions holding ALNY in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Prosight Management, LP31,907$5.41M3.60%+31,907New
Rafferty Asset Management, LLC31,945$5.42M0.03%+15,515+94.4%Added
Jefferies Group LLC31,959$5.42M0.10%+18,515+137.7%Added
Arizona State Retirement System32,359$5.49M0.04%−629−1.9%Reduced
Federation des caisses Desjardins du Quebec32,446$5.50M0.05%−1,569−4.6%Reduced
Envestnet Asset Management Inc34,313$5.82M0.00%+2,828+9.0%Added
Karani Asset Management LLC34,675$5.88M2.91%+2,186+6.7%Added
Logos Global Management LP35,000$5.93M0.61%+35,000New
Erste Asset Management GmbH36,800$6.26M0.11%00.0%Unchanged
Aviva PLC38,217$6.48M0.03%+1,965+5.4%Added
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund39,915$6.77M0.06%−969−2.4%Reduced
Royal London Asset Management Ltd40,303$6.84M0.03%−977−2.4%Reduced
Bank of Montreal39,484$6.85M0.00%−13,857−26.0%Reduced
Ensign Peak Advisors, Inc40,760$6.91M0.01%−127,839−75.8%Reduced
HSBC Holdings PLC41,340$7.02M0.01%+12,626+44.0%Added
Lord, Abbett & Co. LLC42,000$7.12M0.02%−238,000−85.0%Reduced
Rosenblum Silverman Sutton S F Inc42,359$7.18M1.62%−665−1.5%Reduced
Macquarie Group Ltd43,115$7.31M0.01%−10,478−19.6%Reduced
Eaton Vance Management43,335$7.35M0.01%−674−1.5%Reduced
Raymond James & Associates43,503$7.38M0.01%+3,802+9.6%Added
Wells Fargo & Company45,167$7.66M0.00%−91,083−66.8%Reduced
D. E. Shaw & Co., Inc.46,340$7.86M0.01%+13,277+40.2%Added
Skandinaviska Enskilda Banken AB (publ)46,489$7.95M0.04%+5,200+12.6%Added
683 Capital Management, LLC49,000$8.31M0.40%00.0%Unchanged
Allianz Asset Management GmbH51,064$8.67M0.01%−4,490−8.1%Reduced
Great West Life Assurance Co51,477$8.71M0.02%−15,739−23.4%Reduced
Asset Management One Co.,Ltd.52,312$8.90M0.03%−336−0.6%Reduced
Storebrand Asset Management AS52,855$8.96M0.04%−452−0.8%Reduced
Canada Pension Plan Investment Board56,137$9.52M0.01%−35,151−38.5%Reduced
DekaBank Deutsche Girozentrale56,279$9.54M0.02%+11,843+26.7%Added
Victory Capital Management Inc56,362$9.56M0.01%+484+0.9%Added
Parkman Healthcare Partners LLC57,682$9.78M2.21%−17,285−23.1%Reduced
Teachers Retirement System of the State of Kentucky58,126$9.86M0.09%+5,835+11.2%Added
Voya Investment Management LLC58,727$9.96M0.02%+21,248+56.7%Added
Driehaus Capital Management LLC63,011$10.7M0.11%+18,509+41.6%Added
Korea Investment CORP63,062$10.7M0.03%+39,762+170.7%Added
Nomura Asset Management Co Ltd63,527$10.8M0.05%+20,703+48.3%Added
Public Employees Retirement System of Ohio64,791$11.0M0.04%−2,219−3.3%Reduced
BNP Paribas Arbitrage, SA66,019$11.2M0.03%−11,162−14.5%Reduced
Jacobs Levy Equity Management, Inc67,746$11.5M0.08%+67,746New
Citigroup Inc69,310$11.8M0.01%−1,682−2.4%Reduced
Alliancebernstein L.P.69,880$11.8M0.00%+3,194+4.8%Added
Eversept Partners, LP70,240$11.9M0.99%+11,007+18.6%Added
Citadel Advisors LLC70,768$12.0M0.01%+49,889+238.9%Added
State of New Jersey Common Pension Fund D71,899$12.2M0.04%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.75,169$12.8M0.03%−9,294−11.0%Reduced
Treasurer of the State of North Carolina75,784$12.9M0.07%−520−0.7%Reduced
USS Investment Management Ltd75,740$12.9M0.10%00.0%Unchanged
Russell Investments Group, Ltd.75,668$12.9M0.02%+17,891+31.0%Added
Parnassus Investments77,587$13.2M0.03%00.0%Unchanged
Balyasny Asset Management LLC81,241$13.8M0.06%+41,097+102.4%Added
Tobam81,853$13.9M0.62%+72,659+790.3%Added
Barclays PLC81,965$13.9M0.01%−15,510−15.9%Reduced
Morningstar Investment Services LLC82,567$14.0M0.16%+1,973+2.4%Added
Millennium Management LLC83,417$14.1M0.02%+71,585+605.0%Added
UBS Group AG89,473$15.2M0.01%+67,281+303.2%Added
State of Wisconsin Investment Board93,201$15.8M0.03%−6,189−6.2%Reduced
EcoR1 Capital, LLC98,146$16.6M0.53%+98,146New
Van Eck Associates Corp98,614$16.7M0.04%+5,913+6.4%Added
Natixis104,062$17.6M0.06%+1,546+1.5%Added
Credit Suisse AG113,539$19.3M0.02%−44,147−28.0%Reduced
Eagle Health Investments LP113,702$19.3M4.70%+23,600+26.2%Added
Jane Street Group, LLC115,957$19.7M0.04%+100,355+643.2%Added
CIBC Private Wealth Group, LLC118,252$20.1M0.04%−893−0.7%Reduced
Rhumbline Advisers119,832$20.3M0.02%+3,723+3.2%Added
International Biotechnology Trust PLC128,000$21.7M4.84%+53,000+70.7%Added
HighTower Advisors, LLC129,653$22.0M0.05%+123,016+1,853.5%Added
Adage Capital Partners GP, L.L.C.132,300$22.4M0.04%+132,300New
Susquehanna International Group, LLP142,955$24.2M0.04%+98,562+222.0%Added
State Board of Administration of Florida Retirement System147,993$25.1M0.05%−2,091−1.4%Reduced
Assenagon Asset Management S.A.174,443$29.6M0.11%−159,846−47.8%Reduced
National Pension Service175,793$29.8M0.05%−5,310−2.9%Reduced
Rhenman & Partners Asset Management AB175,000$29.9M1.99%+75,000+75.0%Added
Dimensional Fund Advisors LP179,160$30.4M0.01%−8,103−4.3%Reduced
New York State Common Retirement Fund187,641$31.8M0.03%+6,717+3.7%Added
Handelsbanken Fonder AB187,800$31.8M0.16%+167,700+834.3%Added
Tekla Capital Management LLC189,695$32.2M1.04%00.0%Unchanged
Parametric Portfolio Associates LLC205,698$34.9M0.02%−2,839−1.4%Reduced
California State Teachers Retirement System209,732$35.6M0.04%+4,340+2.1%Added
Franklin Resources Inc210,307$35.7M0.01%+60,652+40.5%Added
AXA S.A.213,704$36.2M0.09%+52,272+32.4%Added
Amundi254,255$37.6M0.02%−6,114−2.3%Reduced
Artisan Partners Limited Partnership239,136$40.6M0.05%−3,648−1.5%Reduced
Candriam Luxembourg S.C.A.240,571$40.8M0.26%+107,492+80.8%Added
Eagle Asset Management Inc255,330$43.7M0.19%+1,549+0.6%Added
Bank of America Corp264,478$44.8M0.00%−39,706−13.1%Reduced
Deutsche Bank AG274,648$46.6M0.02%−7,514−2.7%Reduced
California Public Employees Retirement System309,675$52.5M0.04%−9,284−2.9%Reduced
Capital World Investors318,946$54.1M0.01%00.0%Unchanged
Sumitomo Mitsui Trust Holdings, Inc.324,452$55.0M0.03%−8,119−2.4%Reduced
Rock Springs Capital Management LP332,500$56.4M1.30%+21,500+6.9%Added
Charles Schwab Investment Management Inc362,961$61.6M0.02%+10,146+2.9%Added
Avidity Partners Management LP370,000$62.7M1.33%−57,000−13.3%Reduced
Rockefeller Capital Management L.P.386,260$65.5M0.31%+68,160+21.4%Added
TD Asset Management Inc396,473$67.2M0.06%+161,789+68.9%Added
Swedbank AB436,565$74.7M0.13%+670.0%Added
Swiss National Bank451,710$76.6M0.05%−12,900−2.8%Reduced
Mitsubishi UFJ Trust & Banking Corp471,011$79.9M0.17%−15,837−3.3%Reduced
Janus Henderson Group PLC501,333$85.0M0.04%+479,756+2,223.5%Added
First Trust Advisors LP507,096$86.0M0.08%−25,190−4.7%Reduced