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Agios Pharmaceuticals, Inc.

AGIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001439222

In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 1 sale; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Agios Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
238
+21 vs. Q3 2025
Shares held
61.3M
−2.05M (−3.2%) vs. Q3 2025
Total value
$1.67B
−$870.9M (−34.3%) vs. Q3 2025
New holders
65
79 more added
Sold out
44
70 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 238 institutions
Q1 2021: 175 institutionsQ2 2021: 186 institutionsQ3 2021: 165 institutionsQ4 2021: 161 institutionsQ1 2022: 161 institutionsQ2 2022: 157 institutionsQ3 2022: 168 institutionsQ4 2022: 160 institutionsQ1 2023: 165 institutionsQ2 2023: 153 institutionsQ3 2023: 146 institutionsQ4 2023: 170 institutionsQ1 2024: 187 institutionsQ2 2024: 206 institutionsQ3 2024: 208 institutionsQ4 2024: 225 institutionsQ1 2025: 221 institutionsQ2 2025: 216 institutionsQ3 2025: 221 institutionsQ4 2025: 238 institutionsQ1 2026: 234 institutionsQ2 2026: 238 institutions
Value heldQ4 2025: $1.67B
Q1 2021: $3.37BQ2 2021: $3.63BQ3 2021: $2.81BQ4 2021: $1.95BQ1 2022: $1.74BQ2 2022: $1.31BQ3 2022: $1.64BQ4 2022: $1.67BQ1 2023: $1.36BQ2 2023: $1.68BQ3 2023: $1.46BQ4 2023: $1.33BQ1 2024: $1.81BQ2 2024: $2.51BQ3 2024: $2.58BQ4 2024: $1.97BQ1 2025: $1.76BQ2 2025: $2.05BQ3 2025: $2.55BQ4 2025: $1.67BQ1 2026: $2.12BQ2 2026: $2.45B
Institutions holding AGIO and their total value by quarter
QuarterHoldersValue
Q2 2026238$2.45B
Q1 2026234$2.12B
Q4 2025238$1.67B
Q3 2025221$2.55B
Q2 2025216$2.05B
Q1 2025221$1.76B
Q4 2024225$1.97B
Q3 2024208$2.58B
Q2 2024206$2.51B
Q1 2024187$1.81B
Q4 2023170$1.33B
Q3 2023146$1.46B
Q2 2023153$1.68B
Q1 2023165$1.36B
Q4 2022160$1.67B
Q3 2022168$1.64B
Q2 2022157$1.31B
Q1 2022161$1.74B
Q4 2021161$1.95B
Q3 2021165$2.81B
Q2 2021186$3.63B
Q1 2021175$3.37B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding AGIO in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Thurston, Springer, Miller, Herd & Titak, Inc.241$6.56K0.00%+241New
Daiwa Securities Group Inc.204$6.00K0.00%00.0%Unchanged
Comerica Bank209$5.70K0.00%−165−44.1%Reduced
Hillsdale Investment Management Inc.200$5.44K0.00%00.0%Unchanged
Concord Wealth Partners200$5.44K0.00%00.0%Unchanged
GAMMA Investing LLC171$4.66K0.00%−35−17.0%Reduced
Farther Finance Advisors, LLC151$4.11K0.00%−10−6.2%Reduced
Brown Brothers Harriman & Co144$3.92K0.00%+144New
Triumph Capital Management100$2.72K0.00%+100New
Versant Capital Management, Inc92$2.50K0.00%−224−70.9%Reduced
Private Wealth Management Group, LLC83$2.26K0.00%−1−1.2%Reduced
SRS Capital Advisors, Inc.79$2.15K0.00%−623−88.7%Reduced
Bessemer Group Inc76$2.00K0.00%−110−59.1%Reduced
Root Financial Partners, LLC66$1.80K0.00%−40−37.7%Reduced
Pinnacle Wealth Planning Services, Inc.40$1.09K0.00%+40New
Covestor Ltd41$1.00K0.00%−23−35.9%Reduced
EverSource Wealth Advisors, LLC34$9260.00%−28−45.2%Reduced
Raffa Wealth Management, LLC32$8710.00%00.0%Unchanged
Keating Financial Advisory Services, Inc.21$5720.00%+21New
Quadrant Capital Group LLC16$4360.00%00.0%Unchanged
Manchester Capital Management LLC16$4360.00%+16New
Parkside Financial Bank & Trust15$4090.00%−30−66.7%Reduced
Parallel Advisors, LLC12$3270.00%00.0%Unchanged
Allworth Financial LP11$3000.00%−6−35.3%Reduced
Global Retirement Partners, LLC11$2990.00%+11New
SageView Advisory Group, LLC10$2730.00%+10New
Steward Partners Investment Advisory, LLC9$2450.00%00.0%Unchanged
IFP Advisors, Inc6$1630.00%00.0%Unchanged
Essential Partners LLC5$1360.00%−110−95.7%Reduced
Rothschild Investment LLC5$1360.00%−70−93.3%Reduced
Fortitude Family Office, LLC5$1360.00%00.0%Unchanged
JFS Wealth Advisors, LLC4$1090.00%−12−75.0%Reduced
SBI Securities Co., Ltd.4$1090.00%00.0%Unchanged
Bay Harbor Wealth Management, LLC4$1080.00%+1+33.3%Added
Rialto Wealth Management, LLC2$550.00%00.0%Unchanged
Dunhill Financial, LLC2$500.00%+2New
SJS Investment Consulting Inc.1$280.00%−1−50.0%Reduced
Jones Financial Companies LLLP1$270.00%00.0%Unchanged
Bellevue Group AG0$00.00%−3,714,736−100.0%Sold out
Paradigm Biocapital Advisors LP0$00.00%−2,673,555−100.0%Sold out
Commodore Capital LP0$00.00%−2,338,287−100.0%Sold out
Macquarie Group Ltd0$00.00%−1,958,101−100.0%Sold out
Caligan Partners LP0$00.00%−1,131,205−100.0%Sold out
Fisher Asset Management, LLC0$00.00%−870,145−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−800,000−100.0%Sold out
SummitTX Capital, L.P.0$00.00%−262,977−100.0%Sold out
Eagle Health Investments LP0$00.00%−246,230−100.0%Sold out
Baker Bros. Advisors LP0$00.00%−189,866−100.0%Sold out
Peregrine Capital Management LLC0$00.00%−162,905−100.0%Sold out
Alyeska Investment Group, L.P.0$00.00%−146,514−100.0%Sold out
Patient Square Capital LP0$00.00%−133,827−100.0%Sold out
Nantahala Capital Management, LLC0$00.00%−100,000−100.0%Sold out
Phocas Financial Corp.0$00.00%−46,608−100.0%Sold out
Ameriprise Financial Inc0$00.00%−38,428−100.0%Sold out
Guggenheim Capital LLC0$00.00%−15,902−100.0%Sold out
Henshaw Capital LLC0$00.00%−13,227−100.0%Sold out
Savvy Advisors, Inc.0$00.00%−11,993−100.0%Sold out
Omers Administration Corp0$00.00%−11,200−100.0%Sold out
Cinctive Capital Management LP0$00.00%−10,099−100.0%Sold out
Voleon Capital Management LP0$00.00%−6,682−100.0%Sold out
Cerity Partners LLC0$00.00%−6,439−100.0%Sold out
Northcape Wealth Management, LLC0$00.00%−5,240−100.0%Sold out
North Star Asset Management Inc0$00.00%−5,000−100.0%Sold out
Torno Capital, LLC0$00.00%−2,500−100.0%Sold out
BIT Capital GmbH0$00.00%−1,571−100.0%Sold out
GWM Advisors LLC0$00.00%−1,273−100.0%Sold out
Advisory Services Network, LLC0$00.00%−350−100.0%Sold out
Optiver Holding B.V.0$00.00%−310−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−291−100.0%Sold out
NBC Securities, Inc.0$00.00%−241−100.0%Sold out
Spire Wealth Management0$00.00%−230−100.0%Sold out
Mather Group, LLC.0$00.00%−95−100.0%Sold out
Larson Financial Group LLC0$00.00%−74−100.0%Sold out
JPL Wealth Management, LLC0$00.00%−70−100.0%Sold out
Halbert Hargrove Global Advisors, LLC0$00.00%−47−100.0%Sold out
Fifth Third Bancorp0$00.00%−30−100.0%Sold out
MAI Capital Management0$00.00%−25−100.0%Sold out
True Wealth Design, LLC0$00.00%−9−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−6−100.0%Sold out
HFM Investment Advisors, LLC0$00.00%−3−100.0%Sold out
DiNuzzo Private Wealth, Inc.0$00.00%−1−100.0%Sold out
Cloud Capital Management, LLC0$00.00%−1−100.0%Sold out
AXA Investment Managers S.A.––––Not filed
Cubist Systematic Strategies, LLC––––Not filed
CIBC Bancorp USA Inc.––––Not filed
Hemington Wealth Management––––Not filed