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Agios Pharmaceuticals, Inc.

AGIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001439222

In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Agios Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
161
−4 vs. Q3 2021
Shares held
59.2M
−1.69M (−2.8%) vs. Q3 2021
Total value
$1.95B
−$863.3M (−30.7%) vs. Q3 2021
New holders
28
47 more added
Sold out
32
61 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 161 institutions
Q1 2021: 175 institutionsQ2 2021: 186 institutionsQ3 2021: 165 institutionsQ4 2021: 161 institutionsQ1 2022: 161 institutionsQ2 2022: 157 institutionsQ3 2022: 168 institutionsQ4 2022: 160 institutionsQ1 2023: 165 institutionsQ2 2023: 153 institutionsQ3 2023: 146 institutionsQ4 2023: 170 institutionsQ1 2024: 187 institutionsQ2 2024: 206 institutionsQ3 2024: 208 institutionsQ4 2024: 225 institutionsQ1 2025: 221 institutionsQ2 2025: 216 institutionsQ3 2025: 221 institutionsQ4 2025: 238 institutionsQ1 2026: 234 institutionsQ2 2026: 238 institutions
Value heldQ4 2021: $1.95B
Q1 2021: $3.37BQ2 2021: $3.63BQ3 2021: $2.81BQ4 2021: $1.95BQ1 2022: $1.74BQ2 2022: $1.31BQ3 2022: $1.64BQ4 2022: $1.67BQ1 2023: $1.36BQ2 2023: $1.68BQ3 2023: $1.46BQ4 2023: $1.33BQ1 2024: $1.81BQ2 2024: $2.51BQ3 2024: $2.58BQ4 2024: $1.97BQ1 2025: $1.76BQ2 2025: $2.05BQ3 2025: $2.55BQ4 2025: $1.67BQ1 2026: $2.12BQ2 2026: $2.45B
Institutions holding AGIO and their total value by quarter
QuarterHoldersValue
Q2 2026238$2.45B
Q1 2026234$2.12B
Q4 2025238$1.67B
Q3 2025221$2.55B
Q2 2025216$2.05B
Q1 2025221$1.76B
Q4 2024225$1.97B
Q3 2024208$2.58B
Q2 2024206$2.51B
Q1 2024187$1.81B
Q4 2023170$1.33B
Q3 2023146$1.46B
Q2 2023153$1.68B
Q1 2023165$1.36B
Q4 2022160$1.67B
Q3 2022168$1.64B
Q2 2022157$1.31B
Q1 2022161$1.74B
Q4 2021161$1.95B
Q3 2021165$2.81B
Q2 2021186$3.63B
Q1 2021175$3.37B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q3 2021.

Institutions holding AGIO in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC5,434,314$178.6M0.01%−1,414,504−20.7%Reduced
BlackRock Inc.5,408,536$177.8M0.00%−348,591−6.1%Reduced
Wellington Management Group LLP5,148,566$169.2M0.03%−33,787−0.7%Reduced
Vanguard Group Inc5,068,590$166.6M0.00%−377,231−6.9%Reduced
Bellevue Group AG4,349,292$143.0M1.47%+7,300+0.2%Added
JPMorgan Chase & Co3,100,410$101.9M0.01%−1,142,575−26.9%Reduced
State Street Corp2,992,882$98.4M0.00%+599,992+25.1%Added
Price T Rowe Associates Inc2,878,714$94.6M0.01%−152,027−5.0%Reduced
Rock Springs Capital Management LP2,646,625$87.0M2.01%+90,446+3.5%Added
Casdin Capital, LLC2,090,000$68.7M1.94%−75,000−3.5%Reduced
Goldman Sachs Group Inc1,880,931$61.8M0.02%+82,832+4.6%Added
Erste Asset Management GmbH1,578,200$53.0M0.95%+435,000+38.1%Added
ArrowMark Colorado Holdings LLC1,312,164$43.1M0.35%+231,855+21.5%Added
First Trust Advisors LP1,268,470$41.7M0.04%+167,687+15.2%Added
Farallon Capital Management, L.L.C.1,256,578$41.3M0.23%+437,811+53.5%Added
Suvretta Capital Management, LLC1,177,374$38.7M0.75%−134,374−10.2%Reduced
Macquarie Group Ltd1,163,984$38.3M0.03%+8,624+0.7%Added
Geode Capital Management, LLC1,044,016$34.3M0.00%−3,726−0.4%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.860,343$28.3M0.09%+59,929+7.5%Added
Dimensional Fund Advisors LP725,401$23.8M0.01%+184,903+34.2%Added
Northern Trust Corp632,287$20.8M0.00%+27,650+4.6%Added
Deutsche Bank AG571,216$18.8M0.01%−101,216−15.1%Reduced
Eagle Health Investments LP431,413$14.2M3.46%+195,900+83.2%Added
Nuveen Asset Management, LLC392,548$12.9M0.00%−35,742−8.3%Reduced
Charles Schwab Investment Management Inc385,635$12.7M0.00%−24,966−6.1%Reduced
Bank of New York Mellon Corp369,145$12.1M0.00%+89,698+32.1%Added
Jacobs Levy Equity Management, Inc308,041$10.1M0.07%+5,494+1.8%Added
Bank of America Corp282,180$9.28M0.00%+145,719+106.8%Added
Morgan Stanley257,936$8.48M0.00%+81,643+46.3%Added
Norges Bank205,646$6.76M0.00%−89,911−30.4%Reduced
Hudson Bay Capital Management LP200,000$6.57M0.07%+125,000+166.7%Added
UBS Group AG185,425$6.09M0.00%+91,504+97.4%Added
Rafferty Asset Management, LLC178,272$5.86M0.03%+109,293+158.4%Added
Citigroup Inc153,054$5.03M0.00%+98,113+178.6%Added
Swiss National Bank116,760$3.84M0.00%−5,700−4.7%Reduced
D. E. Shaw & Co., Inc.113,866$3.74M0.00%−26,888−19.1%Reduced
Pictet Asset Management SA109,810$3.61M0.00%+4,878+4.6%Added
Principal Financial Group Inc100,819$3.31M0.00%−11,054−9.9%Reduced
Millennium Management LLC90,239$2.97M0.00%+76,651+564.1%Added
TD Asset Management Inc86,815$2.85M0.00%+18,820+27.7%Added
Connor, Clark & Lunn Investment Management Ltd.85,478$2.81M0.01%−18,645−17.9%Reduced
Tudor Investment Corp Et Al83,815$2.75M0.05%+83,815New
Credit Suisse AG83,663$2.75M0.00%−596−0.7%Reduced
Susquehanna International Group, LLP82,041$2.70M0.00%−110,974−57.5%Reduced
Rhumbline Advisers81,765$2.69M0.00%−4,239−4.9%Reduced
State of Wisconsin Investment Board79,900$2.63M0.01%00.0%Unchanged
Eaton Vance Management74,972$2.46M0.00%00.0%Unchanged
California State Teachers Retirement System74,513$2.45M0.00%−2,817−3.6%Reduced
State of New Jersey Common Pension Fund D73,486$2.42M0.01%+10,680+17.0%Added
Alliancebernstein L.P.73,360$2.41M0.00%00.0%Unchanged
Barclays PLC69,815$2.29M0.00%+43,391+164.2%Added
Jane Street Group, LLC68,099$2.24M0.00%+954+1.4%Added
Cubist Systematic Strategies, LLC67,029$2.20M0.02%+51,323+326.8%Added
Ergoteles LLC65,824$2.16M0.08%+65,824New
UBS Asset Management Americas Inc64,701$2.13M0.00%−1,526−2.3%Reduced
Alps Advisors Inc62,849$2.07M0.02%−9,405−13.0%Reduced
Russell Investments Group, Ltd.58,600$1.93M0.00%−48,694−45.4%Reduced
Gsa Capital Partners LLP58,059$1.91M0.24%+58,059New
Duality Advisers, LP54,530$1.79M0.19%+54,530New
Wells Fargo & Company52,969$1.74M0.00%−21,310−28.7%Reduced
Allianz Asset Management GmbH50,500$1.67M0.00%+870+1.8%Added
Parametric Portfolio Associates LLC49,475$1.63M0.00%−25,649−34.1%Reduced
Legal & General Group Plc48,459$1.59M0.00%−894−1.8%Reduced
SG Americas Securities, LLC46,263$1.52M0.01%+9,663+26.4%Added
Voloridge Investment Management, LLC45,079$1.48M0.01%+27,640+158.5%Added
Squarepoint Ops LLC42,629$1.40M0.01%+42,629New
Alaska Permanent Fund Corp44,700$1.38M0.03%00.0%Unchanged
New York State Common Retirement Fund41,699$1.37M0.00%−7,667−15.5%Reduced
Caption Management, LLC41,000$1.35M0.08%+41,000New
HRT Financial LP38,805$1.27M0.01%+38,805New
BNP Paribas Arbitrage, SA35,601$1.17M0.00%+7,879+28.4%Added
Allspring Global Investments Holdings, LLC34,289$1.13M0.00%+34,289New
Qube Research & Technologies Ltd34,241$1.13M0.01%+34,241New
Skandinaviska Enskilda Banken AB (publ)32,545$1.09M0.01%00.0%Unchanged
Invesco Ltd.33,133$1.09M0.00%−4,691−12.4%Reduced
AlphaCrest Capital Management LLC28,931$951.0K0.04%+12,207+73.0%Added
American International Group, Inc.28,876$949.0K0.00%−3,407−10.6%Reduced
Royal Bank of Canada28,565$940.0K0.00%−1,967−6.4%Reduced
Manufacturers Life Insurance Company, The28,161$936.0K0.00%−2,525−8.2%Reduced
Virginia Retirement Systems Et Al26,600$874.0K0.01%−4,400−14.2%Reduced
State Board of Administration of Florida Retirement System24,587$808.0K0.00%00.0%Unchanged
Voya Investment Management LLC22,095$726.0K0.00%−1,132−4.9%Reduced
International Biotechnology Trust PLC21,500$707.0K0.16%00.0%Unchanged
ProShare Advisors LLC20,882$687.0K0.00%−664−3.1%Reduced
Hennion & Walsh Asset Management, Inc.20,515$674.0K0.03%+1,283+6.7%Added
MetLife Investment Management20,321$668.0K0.01%00.0%Unchanged
Citadel Advisors LLC20,229$665.0K0.00%−78,253−79.5%Reduced
Winton Group Ltd18,756$617.0K0.04%−11,756−38.5%Reduced
Metropolitan Life Insurance Co15,565$511.6K0.01%00.0%Unchanged
Marshall Wace, LLP14,581$479.0K0.00%+14,581New
Arizona State Retirement System14,280$469.0K0.00%−815−5.4%Reduced
ETF Managers Group, LLC13,233$444.0K0.01%+630+5.0%Added
Tower Research Capital LLC (TRC)13,063$429.0K0.01%+8,921+215.4%Added
Janus Henderson Group PLC12,694$418.0K0.00%+6,374+100.9%Added
Victory Capital Management Inc12,227$402.0K0.00%−40,899−77.0%Reduced
Ensign Peak Advisors, Inc12,180$400.0K0.00%+12,180New
Handelsbanken Fonder AB11,723$385.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC11,541$379.0K0.14%+3,692+47.0%Added
AlphaCentric Advisors LLC11,500$378.0K0.11%+11,500New
Schonfeld Strategic Advisors LLC11,300$371.0K0.00%+11,300New