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Agios Pharmaceuticals, Inc.

AGIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001439222

In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Agios Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
216
−3 vs. Q1 2025
Shares held
61.7M
+1.64M (+2.7%) vs. Q1 2025
Total value
$2.05B
+$290.1M (+16.5%) vs. Q1 2025
New holders
22
87 more added
Sold out
25
77 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 216 institutions
Q1 2021: 175 institutionsQ2 2021: 186 institutionsQ3 2021: 165 institutionsQ4 2021: 161 institutionsQ1 2022: 161 institutionsQ2 2022: 157 institutionsQ3 2022: 168 institutionsQ4 2022: 160 institutionsQ1 2023: 165 institutionsQ2 2023: 153 institutionsQ3 2023: 146 institutionsQ4 2023: 170 institutionsQ1 2024: 187 institutionsQ2 2024: 206 institutionsQ3 2024: 208 institutionsQ4 2024: 225 institutionsQ1 2025: 221 institutionsQ2 2025: 216 institutionsQ3 2025: 221 institutionsQ4 2025: 238 institutionsQ1 2026: 234 institutionsQ2 2026: 238 institutions
Value heldQ2 2025: $2.05B
Q1 2021: $3.37BQ2 2021: $3.63BQ3 2021: $2.81BQ4 2021: $1.95BQ1 2022: $1.74BQ2 2022: $1.31BQ3 2022: $1.64BQ4 2022: $1.67BQ1 2023: $1.36BQ2 2023: $1.68BQ3 2023: $1.46BQ4 2023: $1.33BQ1 2024: $1.81BQ2 2024: $2.51BQ3 2024: $2.58BQ4 2024: $1.97BQ1 2025: $1.76BQ2 2025: $2.05BQ3 2025: $2.55BQ4 2025: $1.67BQ1 2026: $2.12BQ2 2026: $2.45B
Institutions holding AGIO and their total value by quarter
QuarterHoldersValue
Q2 2026238$2.45B
Q1 2026234$2.12B
Q4 2025238$1.67B
Q3 2025221$2.55B
Q2 2025216$2.05B
Q1 2025221$1.76B
Q4 2024225$1.97B
Q3 2024208$2.58B
Q2 2024206$2.51B
Q1 2024187$1.81B
Q4 2023170$1.33B
Q3 2023146$1.46B
Q2 2023153$1.68B
Q1 2023165$1.36B
Q4 2022160$1.67B
Q3 2022168$1.64B
Q2 2022157$1.31B
Q1 2022161$1.74B
Q4 2021161$1.95B
Q3 2021165$2.81B
Q2 2021186$3.63B
Q1 2021175$3.37B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding AGIO in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Farallon Capital Management, L.L.C.5,767,466$191.8M0.87%+67,000+1.2%Added
Vanguard Group Inc5,682,019$189.0M0.00%+77,428+1.4%Added
BlackRock, Inc.4,833,760$160.8M0.00%−274,986−5.4%Reduced
Bellevue Group AG3,590,150$119.4M2.63%+75,000+2.1%Added
Erste Asset Management GmbH2,326,489$77.4M0.65%+96,589+4.3%Added
Commodore Capital LP2,325,000$77.3M5.46%+140,000+6.4%Added
Price T Rowe Associates Inc2,274,249$75.6M0.01%−27,104−1.2%Reduced
State Street Corp1,951,113$64.9M0.00%−498,366−20.3%Reduced
Macquarie Group Ltd1,900,596$63.2M0.08%+50,052+2.7%Added
Geode Capital Management, LLC1,405,755$46.8M0.00%+11,174+0.8%Added
Frazier Life Sciences Management, L.P.1,279,754$42.6M1.70%+209,900+19.6%Added
Armistice Capital, LLC1,168,000$38.8M1.47%−880,000−43.0%Reduced
Paradigm Biocapital Advisors LP1,142,511$38.0M1.62%+1,142,511New
Bank of America Corp1,120,308$37.3M0.00%−15,284−1.3%Reduced
Dimensional Fund Advisors LP1,106,093$36.8M0.01%−155,980−12.4%Reduced
Citadel Advisors LLC1,081,470$36.0M0.03%+217,971+25.2%Added
Caligan Partners LP1,071,258$35.6M6.92%+369,978+52.8%Added
JPMorgan Chase & Co1,027,417$34.2M0.00%−21,943−2.1%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,016,891$33.8M0.08%−8,828−0.9%Reduced
Rock Springs Capital Management LP989,745$32.9M2.05%+647,565+189.2%Added
Deutsche Bank AG921,586$30.7M0.01%−7,384−0.8%Reduced
Fisher Asset Management, LLC877,540$29.2M0.01%−81,799−8.5%Reduced
GW&K Investment Management, LLC868,618$28.9M0.26%+51,092+6.2%Added
Adage Capital Partners GP, L.L.C.791,000$26.3M0.04%+48,000+6.5%Added
TCG Crossover Management, LLC697,003$23.2M2.65%+697,003New
Marshall Wace, LLP684,669$22.8M0.03%+163,796+31.4%Added
ArrowMark Colorado Holdings LLC658,691$21.9M0.39%−168,932−20.4%Reduced
Goldman Sachs Group Inc648,061$21.6M0.00%−10,591−1.6%Reduced
SCS Capital Management LLC604,085$20.1M0.22%−7,013−1.1%Reduced
D. E. Shaw & Co., Inc.596,202$19.8M0.02%+41,382+7.5%Added
OrbiMed Advisors LLC557,900$18.6M0.47%+232,400+71.4%Added
Northern Trust Corp556,805$18.5M0.00%−19,453−3.4%Reduced
Connor, Clark & Lunn Investment Management Ltd.505,225$16.8M0.06%+118,702+30.7%Added
Charles Schwab Investment Management Inc476,041$15.8M0.00%+11,083+2.4%Added
Boothbay Fund Management, LLC447,019$14.9M0.47%+185,798+71.1%Added
Wellington Management Group LLP422,129$14.0M0.00%+397,667+1,625.7%Added
Artisan Partners Limited Partnership389,984$13.0M0.02%−20,688−5.0%Reduced
Eagle Health Investments LP330,830$11.0M2.72%00.0%Unchanged
Millennium Management LLC300,203$9.98M0.01%+247,130+465.6%Added
Pictet Asset Management Holding SA294,740$9.86M0.01%−16,041−5.2%Reduced
Morgan Stanley291,965$9.71M0.00%−2,658−0.9%Reduced
Palo Alto Investors LP268,783$8.94M1.90%−7,795−2.8%Reduced
Bank of New York Mellon Corp266,654$8.87M0.00%+3,204+1.2%Added
CenterBook Partners LP243,063$8.08M0.45%+134,554+124.0%Added
Woodline Partners LP233,068$7.75M0.04%+212,687+1,043.6%Added
Nordea Investment Management AB224,746$7.52M0.01%+573+0.3%Added
AXA S.A.225,367$7.50M0.02%+248+0.1%Added
UBS Asset Management Americas Inc217,402$7.23M0.00%+70,126+47.6%Added
Baker Bros. Advisors LP189,866$6.31M0.06%+189,866New
Voloridge Investment Management, LLC187,395$6.23M0.02%−144,248−43.5%Reduced
Barclays PLC180,704$6.01M0.00%+67,551+59.7%Added
TD Asset Management Inc168,194$5.59M0.00%−9,878−5.5%Reduced
Prudential Financial Inc158,359$5.27M0.01%−45,883−22.5%Reduced
Patient Square Capital LP139,732$4.65M1.68%00.0%Unchanged
Allianz Asset Management GmbH138,898$4.62M0.01%+46,665+50.6%Added
Cantor Fitzgerald, L. P.134,200$4.46M0.11%+102,200+319.4%Added
Manufacturers Life Insurance Company, The132,083$4.39M0.00%+512+0.4%Added
Hudson Bay Capital Management LP130,000$4.32M0.03%+19,280+17.4%Added
American Century Companies Inc127,647$4.25M0.00%+12,700+11.0%Added
Nuveen, LLC119,580$3.98M0.00%+36,171+43.4%Added
UBS Group AG118,834$3.95M0.00%−12,808−9.7%Reduced
Invesco Ltd.112,617$3.75M0.00%+5,250+4.9%Added
Swiss National Bank109,460$3.64M0.00%+10,000+10.1%Added
Casdin Capital, LLC100,000$3.33M0.30%−150,000−60.0%Reduced
Trexquant Investment LP98,401$3.27M0.04%+98,401New
AQR Capital Management LLC96,896$3.21M0.00%+45,407+88.2%Added
Rhumbline Advisers89,881$2.99M0.00%+3,039+3.5%Added
Algert Global LLC88,830$2.95M0.06%+14,020+18.7%Added
Silvercrest Asset Management Group LLC82,679$2.75M0.02%00.0%Unchanged
Moore Capital Management, LP80,000$2.66M0.05%+20,000+33.3%Added
HighVista Strategies LLC70,127$2.33M0.86%+26,022+59.0%Added
Capital Fund Management S.A.68,502$2.28M0.03%−3,800−5.3%Reduced
Susquehanna International Group, LLP68,103$2.27M0.00%−13,859−16.9%Reduced
Qube Research & Technologies Ltd67,379$2.24M0.00%−60,601−47.4%Reduced
Legal & General Group Plc64,305$2.14M0.00%+4,262+7.1%Added
Alliancebernstein L.P.61,470$2.04M0.00%−80.0%Reduced
State of Wisconsin Investment Board59,100$1.97M0.00%−10,584−15.2%Reduced
UBS Oconnor LLC56,810$1.89M0.05%−1,912−3.3%Reduced
Citigroup Inc56,489$1.88M0.00%−119,639−67.9%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH55,284$1.84M0.00%+633+1.2%Added
Ameriprise Financial Inc52,252$1.74M0.00%+5,441+11.6%Added
Franklin Resources Inc50,108$1.67M0.00%−17,964−26.4%Reduced
Virginia Retirement Systems Et Al49,661$1.65M0.01%+10,400+26.5%Added
Rafferty Asset Management, LLC49,403$1.64M0.01%−44,224−47.2%Reduced
California State Teachers Retirement System47,659$1.59M0.00%+671+1.4%Added
Panagora Asset Management Inc47,190$1.57M0.01%−31−0.1%Reduced
Schonfeld Strategic Advisors LLC46,346$1.54M0.01%+22,746+96.4%Added
Granahan Investment Management Inc41,886$1.39M0.06%−90,222−68.3%Reduced
DekaBank Deutsche Girozentrale40,000$1.33M0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.39,579$1.32M0.00%−3,748−8.7%Reduced
New York State Common Retirement Fund39,093$1.30M0.00%00.0%Unchanged
Wells Fargo & Company37,694$1.25M0.00%−30,443−44.7%Reduced
Oak Ridge Investments LLC37,252$1.24M0.09%−1,835−4.7%Reduced
Harbor Capital Advisors, Inc.37,024$1.23M0.05%+1,295+3.6%Added
Kennedy Capital Management, Inc.36,705$1.22M0.03%−26,248−41.7%Reduced
First Trust Advisors LP36,427$1.21M0.00%−903−2.4%Reduced
ADAR1 Capital Management, LLC35,900$1.19M0.19%+8,000+28.7%Added
Edgewood Management LLC35,000$1.16M0.00%00.0%Unchanged
MetLife Investment Management34,032$1.13M0.01%00.0%Unchanged
Jane Street Group, LLC33,489$1.11M0.00%−92,615−73.4%Reduced