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Agios Pharmaceuticals, Inc.

AGIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001439222

In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Agios Pharmaceuticals, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
216
−3 vs. Q1 2025
Shares held
61.7M
+1.64M (+2.7%) vs. Q1 2025
Total value
$2.05B
+$290.1M (+16.5%) vs. Q1 2025
New holders
22
87 more added
Sold out
25
77 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 216 institutions
Q1 2021: 175 institutionsQ2 2021: 186 institutionsQ3 2021: 165 institutionsQ4 2021: 161 institutionsQ1 2022: 161 institutionsQ2 2022: 157 institutionsQ3 2022: 168 institutionsQ4 2022: 160 institutionsQ1 2023: 165 institutionsQ2 2023: 153 institutionsQ3 2023: 146 institutionsQ4 2023: 170 institutionsQ1 2024: 187 institutionsQ2 2024: 206 institutionsQ3 2024: 208 institutionsQ4 2024: 225 institutionsQ1 2025: 221 institutionsQ2 2025: 216 institutionsQ3 2025: 221 institutionsQ4 2025: 238 institutionsQ1 2026: 234 institutionsQ2 2026: 238 institutions
Value heldQ2 2025: $2.05B
Q1 2021: $3.37BQ2 2021: $3.63BQ3 2021: $2.81BQ4 2021: $1.95BQ1 2022: $1.74BQ2 2022: $1.31BQ3 2022: $1.64BQ4 2022: $1.67BQ1 2023: $1.36BQ2 2023: $1.68BQ3 2023: $1.46BQ4 2023: $1.33BQ1 2024: $1.81BQ2 2024: $2.51BQ3 2024: $2.58BQ4 2024: $1.97BQ1 2025: $1.76BQ2 2025: $2.05BQ3 2025: $2.55BQ4 2025: $1.67BQ1 2026: $2.12BQ2 2026: $2.45B
Institutions holding AGIO and their total value by quarter
QuarterHoldersValue
Q2 2026238$2.45B
Q1 2026234$2.12B
Q4 2025238$1.67B
Q3 2025221$2.55B
Q2 2025216$2.05B
Q1 2025221$1.76B
Q4 2024225$1.97B
Q3 2024208$2.58B
Q2 2024206$2.51B
Q1 2024187$1.81B
Q4 2023170$1.33B
Q3 2023146$1.46B
Q2 2023153$1.68B
Q1 2023165$1.36B
Q4 2022160$1.67B
Q3 2022168$1.64B
Q2 2022157$1.31B
Q1 2022161$1.74B
Q4 2021161$1.95B
Q3 2021165$2.81B
Q2 2021186$3.63B
Q1 2021175$3.37B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q1 2025.

Institutions holding AGIO in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Alps Advisors Inc31,274$1.04M0.01%−10,945−25.9%Reduced
Victory Capital Management Inc29,414$978.3K0.00%+20,630+234.9%Added
Brevan Howard Capital Management LP29,177$970.4K0.01%+29,177New
Ensign Peak Advisors, Inc24,970$830.5K0.00%−6,950−21.8%Reduced
Janus Henderson Group PLC23,797$790.8K0.00%00.0%Unchanged
Royal Bank of Canada23,164$770.0K0.00%−10,073−30.3%Reduced
Intech Investment Management LLC22,793$758.1K0.01%−12,496−35.4%Reduced
Savvy Advisors, Inc.21,781$724.4K0.05%+21,781New
Great West Life Assurance Co19,663$654.0K0.00%+255+1.3%Added
Handelsbanken Fonder AB19,323$643.0K0.00%00.0%Unchanged
FMR LLC18,592$618.4K0.00%+786+4.4%Added
Guggenheim Capital LLC17,904$595.5K0.00%−851−4.5%Reduced
Fox Run Management, L.L.C.17,707$588.9K0.10%+17,707New
Thrivent Financial for Lutherans17,526$583.0K0.00%00.0%Unchanged
Caption Management, LLC17,000$565.4K0.05%−53,000−75.7%Reduced
Arizona State Retirement System16,676$554.6K0.00%+1,978+13.5%Added
Engineers Gate Manager LP16,548$550.4K0.01%−6,169−27.2%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)16,396$545.3K0.00%+3,560+27.7%Added
State Board of Administration of Florida Retirement System15,847$527.1K0.00%00.0%Unchanged
Toroso Investments, LLC15,560$517.5K0.00%−3,658−19.0%Reduced
Voya Investment Management LLC15,408$512.5K0.00%+161+1.1%Added
Teacher Retirement System of Texas15,405$512.4K0.00%+1,592+11.5%Added
Centiva Capital, LP15,040$500.2K0.03%+8+0.1%Added
Hennion & Walsh Asset Management, Inc.15,005$499.1K0.02%+15,005New
Polar Asset Management Partners Inc.14,700$488.9K0.01%+14,700New
Henshaw Capital LLC14,041$467.0K0.02%00.0%Unchanged
ProShare Advisors LLC13,744$457.1K0.00%−1,077−7.3%Reduced
Atria Investments LLC13,473$448.1K0.01%−1,122−7.7%Reduced
Police & Firemen's Retirement System of New Jersey12,923$429.8K0.00%+891+7.4%Added
Virtus Investment Advisers, Inc.12,881$428.4K0.14%+3,473+36.9%Added
Creative Planning12,839$427.0K0.00%+917+7.7%Added
Headlands Technologies LLC12,644$420.5K0.05%+1,929+18.0%Added
BNP Paribas Arbitrage, SA11,908$396.1K0.00%+7,572+174.6%Added
KLP Kapitalforvaltning AS11,800$392.5K0.00%+1,800+18.0%Added
CWM Advisors, LLC11,728$390.1K0.04%−40−0.3%Reduced
China Universal Asset Management Co., Ltd.11,632$386.9K0.04%+139+1.2%Added
Gallagher Fiduciary Advisors, LLC11,473$381.6K0.01%−1,357−10.6%Reduced
Profund Advisors LLC10,851$360.9K0.01%−8,731−44.6%Reduced
SEI Investments Co10,326$343.4K0.00%−3,421−24.9%Reduced
Envestnet Asset Management Inc10,100$335.9K0.00%−12,453−55.2%Reduced
Commerce Bank9,604$319.4K0.00%+1,405+17.1%Added
Russell Investments Group, Ltd.9,292$309.1K0.00%+734+8.6%Added
Two Sigma Securities, LLC8,646$287.6K0.04%+8,646New
Ieq Capital, LLC8,086$268.9K0.00%+8,086New
Jain Global LLC7,749$257.7K0.00%+7,749New
CIBC World Markets Corp6,959$231.5K0.00%−5,582−44.5%Reduced
Public Employees Retirement Association of Colorado6,796$226.0K0.00%00.0%Unchanged
Cerity Partners LLC6,789$225.8K0.00%+6,789New
Norges Bank6,756$224.7K0.00%−70,788−91.3%Reduced
Tower Research Capital LLC (TRC)6,440$214.2K0.01%+5,563+634.3%Added
Ameritas Investment Partners, Inc.5,913$196.7K0.01%00.0%Unchanged
CWM, LLC5,286$176.0K0.00%+3,627+218.6%Added
The PNC Financial Services Group, Inc.4,419$147.0K0.00%+837+23.4%Added
Mirae Asset Global Investments Co., Ltd.2,237$74.4K0.00%+320+16.7%Added
BIT Capital GmbH2,230$74.2K0.00%−19,238−89.6%Reduced
Amalgamated Bank1,957$65.0K0.00%00.0%Unchanged
Bryn Mawr Trust Co1,885$62.7K0.00%−226−10.7%Reduced
KBC Group NV1,751$58.0K0.00%−864−33.0%Reduced
Sterling Capital Management LLC1,515$50.4K0.00%+540+55.4%Added
GF Fund Management Co. Ltd.1,460$48.6K0.00%00.0%Unchanged
GWM Advisors LLC1,273$42.3K0.00%−82−6.1%Reduced
Skopos Labs, Inc.1,130$37.6K0.00%+1,130New
STRS Ohio1,100$36.6K0.00%−7,100−86.6%Reduced
Assetmark, Inc955$31.8K0.00%+150+18.6%Added
Nisa Investment Advisors, LLC780$25.9K0.00%−42−5.1%Reduced
Quest Partners LLC669$22.3K0.00%+296+79.4%Added
Federated Hermes, Inc.597$19.9K0.00%−15,288−96.2%Reduced
US Bancorp569$18.9K0.00%+10+1.8%Added
First Horizon Advisors, Inc.523$17.4K0.00%−21−3.9%Reduced
Signaturefd, LLC513$17.1K0.00%+36+7.5%Added
Lazard Asset Management LLC534$17.0K0.00%−2,124−79.9%Reduced
Raymond James Financial Inc442$14.7K0.00%+442New
Hurley Capital, LLC366$12.2K0.01%00.0%Unchanged
Aspect Partners, LLC361$12.0K0.01%00.0%Unchanged
Comerica Bank353$11.7K0.00%+163+85.8%Added
Advisor Group Holdings, Inc.347$11.5K0.00%+312+891.4%Added
NBC Securities, Inc.345$11.0K0.00%00.0%Unchanged
Versant Capital Management, Inc316$10.5K0.00%+316New
Optiver Holding B.V.305$10.1K0.00%+90+41.9%Added
Bell Investment Advisors, Inc298$9.91K0.00%+61+25.7%Added
Clearstead Advisors, LLC291$9.68K0.00%+291New
Kestra Investment Management, LLC278$8.70K0.00%+139+100.0%Added
Spire Wealth Management230$7.65K0.00%00.0%Unchanged
Daiwa Securities Group Inc.204$7.00K0.00%00.0%Unchanged
Hillsdale Investment Management Inc.200$6.65K0.00%00.0%Unchanged
Concord Wealth Partners200$6.65K0.00%00.0%Unchanged
GAMMA Investing LLC183$6.09K0.00%−96−34.4%Reduced
Smartleaf Asset Management LLC167$5.59K0.00%−147−46.8%Reduced
Farther Finance Advisors, LLC151$5.02K0.00%+139+1,158.3%Added
Bessemer Group Inc110$4.00K0.00%00.0%Unchanged
Essential Partners LLC115$3.83K0.00%+115New
Rothschild Investment LLC90$2.99K0.00%−20−18.2%Reduced
Private Wealth Management Group, LLC84$2.79K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC62$2.06K0.00%+21+51.2%Added
IFP Advisors, Inc0$1.86K0.00%0New
Parkside Financial Bank & Trust45$1.49K0.00%+15+50.0%Added
MAI Capital Management34$1.13K0.00%−4−10.5%Reduced
Raffa Wealth Management, LLC32$1.06K0.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd21$6980.00%−24−53.3%Reduced
JFS Wealth Advisors, LLC16$5330.00%+11+220.0%Added