Agios Pharmaceuticals, Inc.
AGIO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001439222
In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Agios Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 234
- −1 vs. Q4 2025
- Shares held
- 63.1M
- +7.41M (+13.3%) vs. Q4 2025
- Total value
- $2.12B
- +$605.4M (+40.0%) vs. Q4 2025
- New holders
- 36
- 82 more added
- Sold out
- 37
- 82 more reduced
3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 238 | $2.45B |
| Q1 2026 | 234 | $2.12B |
| Q4 2025 | 238 | $1.67B |
| Q3 2025 | 221 | $2.55B |
| Q2 2025 | 216 | $2.05B |
| Q1 2025 | 221 | $1.76B |
| Q4 2024 | 225 | $1.97B |
| Q3 2024 | 208 | $2.58B |
| Q2 2024 | 206 | $2.51B |
| Q1 2024 | 187 | $1.81B |
| Q4 2023 | 170 | $1.33B |
| Q3 2023 | 146 | $1.46B |
| Q2 2023 | 153 | $1.68B |
| Q1 2023 | 165 | $1.36B |
| Q4 2022 | 160 | $1.67B |
| Q3 2022 | 168 | $1.64B |
| Q2 2022 | 157 | $1.31B |
| Q1 2022 | 161 | $1.74B |
| Q4 2021 | 161 | $1.95B |
| Q3 2021 | 165 | $2.81B |
| Q2 2021 | 186 | $3.63B |
| Q1 2021 | 175 | $3.37B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 5,754,957 | $194.7M | 0.00% | +519,528+9.9% | Added |
| Farallon Capital Management, L.L.C. | 5,684,000 | $192.3M | 1.14% | +524,495+10.2% | Added |
| State Street Corp | 3,364,879 | $113.7M | 0.00% | +256,734+8.3% | Added |
| Armistice Capital, LLC | 2,716,000 | $91.9M | 3.03% | −320,000−10.5% | Reduced |
| D. E. Shaw & Co., Inc. | 2,681,169 | $90.7M | 0.07% | +843,983+45.9% | Added |
| Vanguard Capital Management LLC | 2,632,316 | $89.1M | 0.00% | +2,632,316 | New |
| Lynx1 Capital Management LP | 2,611,568 | $88.3M | 13.96% | +2,531,944+3,179.9% | Added |
| Vanguard Portfolio Management LLC | 2,611,035 | $88.3M | 0.00% | +2,611,035 | New |
| Erste Asset Management GmbH | 2,704,900 | $80.1M | 0.74% | −100,000−3.6% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,580,840 | $53.5M | 0.06% | +220,110+16.2% | Added |
| Nomura Asset Management International Inc. | 1,494,435 | $50.6M | 0.09% | −206,974−12.2% | Reduced |
| T. Rowe Price Investment Management, Inc. | 1,488,740 | $50.4M | 0.03% | +1,487,848+166,799.1% | Added |
| Geode Capital Management, LLC | 1,467,910 | $49.7M | 0.00% | +54,372+3.8% | Added |
| Susquehanna International Group, LLP | 1,344,953 | $45.5M | 0.06% | +202,521+17.7% | Added |
| MPM Oncology Impact Management LP | 1,306,261 | $44.2M | 3.41% | +2,888+0.2% | Added |
| Frazier Life Sciences Management, L.P. | 1,256,080 | $42.5M | 1.09% | −23,674−1.8% | Reduced |
| GW&K Investment Management, LLC | 1,214,901 | $41.1M | 0.36% | +7,600+0.6% | Added |
| Dimensional Fund Advisors LP | 1,151,614 | $38.9M | 0.01% | +147,273+14.7% | Added |
| Morgan Stanley | 967,525 | $32.7M | 0.00% | +73,488+8.2% | Added |
| Goldman Sachs Group Inc | 805,776 | $27.3M | 0.00% | −228,198−22.1% | Reduced |
| Rock Springs Capital Management LP | 799,163 | $27.0M | 1.59% | 00.0% | Unchanged |
| Nuveen, LLC | 722,348 | $24.4M | 0.01% | +424,440+142.5% | Added |
| Jane Street Group, LLC | 685,240 | $23.2M | 0.02% | −435,810−38.9% | Reduced |
| Wellington Management Group LLP | 641,486 | $21.7M | 0.00% | +43,660+7.3% | Added |
| Citadel Advisors LLC | 619,613 | $21.0M | 0.01% | −729,355−54.1% | Reduced |
| SCS Capital Management LLC | 612,850 | $20.7M | 0.22% | +14,085+2.4% | Added |
| Foresite Capital Management VI LLC | 525,000 | $17.8M | 3.86% | −5,000−0.9% | Reduced |
| Northern Trust Corp | 509,272 | $17.2M | 0.00% | −2,629−0.5% | Reduced |
| Bank of America Corp | 507,900 | $17.2M | 0.00% | −31,441−5.8% | Reduced |
| Artisan Partners Limited Partnership | 481,516 | $16.3M | 0.03% | −22,969−4.6% | Reduced |
| Charles Schwab Investment Management Inc | 477,032 | $16.1M | 0.00% | −5,590−1.2% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 450,093 | $15.2M | 0.04% | −112,549−20.0% | Reduced |
| Vestal Point Capital, LP | 450,000 | $15.2M | 0.43% | +125,000+38.5% | Added |
| Marshall Wace, LLP | 448,118 | $15.2M | 0.02% | +94,479+26.7% | Added |
| Legal & General Group Plc | 423,915 | $14.3M | 0.00% | +95,704+29.2% | Added |
| ArrowMark Colorado Holdings LLC | 403,590 | $13.7M | 0.36% | −62,561−13.4% | Reduced |
| Parkman Healthcare Partners LLC | 403,525 | $13.7M | 1.42% | +303,921+305.1% | Added |
| Vanguard Fiduciary Trust Co | 382,021 | $12.9M | 0.00% | +382,021 | New |
| BNP Paribas Arbitrage, SA | 327,457 | $11.1M | 0.01% | +84,787+34.9% | Added |
| Price T Rowe Associates Inc | 298,783 | $10.1M | 0.00% | −339,103−53.2% | Reduced |
| Kennedy Capital Management, Inc. | 275,456 | $9.32M | 0.20% | +209,801+319.6% | Added |
| Algert Global LLC | 268,435 | $9.08M | 0.14% | −145,783−35.2% | Reduced |
| Two Sigma Investments, LP | 251,636 | $8.51M | 0.01% | −48,520−16.2% | Reduced |
| Arrowstreet Capital, Limited Partnership | 250,461 | $8.47M | 0.00% | +250,461 | New |
| Panagora Asset Management Inc | 238,468 | $8.07M | 0.03% | +158,628+198.7% | Added |
| Palo Alto Investors LP | 213,601 | $7.23M | 1.11% | +1,102+0.5% | Added |
| Seven Fleet Capital Management LP | 209,547 | $7.09M | 2.23% | +177,809+560.2% | Added |
| Squarepoint Ops LLC | 208,888 | $7.07M | 0.02% | +87,125+71.6% | Added |
| Schonfeld Strategic Advisors LLC | 200,061 | $6.77M | 0.06% | +200,061 | New |
| Eversept Partners, LP | 200,000 | $6.77M | 0.45% | +200,000 | New |
| HRT Financial LP | 195,432 | $6.61M | 0.02% | +48,963+33.4% | Added |
| Qube Research & Technologies Ltd | 187,667 | $6.35M | 0.01% | −190,706−50.4% | Reduced |
| Bank of New York Mellon Corp | 186,791 | $6.32M | 0.00% | −10,102−5.1% | Reduced |
| Group One Trading, L.P. | 173,279 | $5.86M | 0.19% | +6,665+4.0% | Added |
| Polygon Management Ltd. | 164,839 | $5.58M | 1.10% | +2,821+1.7% | Added |
| XTX Topco Ltd | 160,880 | $5.44M | 0.09% | +114,841+249.4% | Added |
| Invesco Ltd. | 151,430 | $5.12M | 0.00% | +8,850+6.2% | Added |
| Man Group plc | 144,297 | $4.88M | 0.01% | +144,297 | New |
| Edgestream Partners, L.P. | 143,731 | $4.86M | 0.16% | −24,267−14.4% | Reduced |
| ADAR1 Capital Management, LLC | 140,672 | $4.76M | 0.29% | −47,328−25.2% | Reduced |
| JPMorgan Chase & Co | 151,558 | $4.49M | 0.00% | −100,219−39.8% | Reduced |
| UBS Group AG | 132,540 | $4.48M | 0.00% | +5,875+4.6% | Added |
| Capital Fund Management S.A. | 129,531 | $4.38M | 0.04% | +93,743+261.9% | Added |
| Exome Asset Management LLC | 125,060 | $4.23M | 2.49% | −11,882−8.7% | Reduced |
| American Century Companies Inc | 120,253 | $4.07M | 0.00% | −31,233−20.6% | Reduced |
| Pictet Asset Management Holding SA | 128,814 | $3.85M | 0.00% | −76,205−37.2% | Reduced |
| UBS Asset Management Americas Inc | 110,679 | $3.74M | 0.00% | +3,683+3.4% | Added |
| Swiss National Bank | 108,860 | $3.68M | 0.00% | 00.0% | Unchanged |
| Essex Investment Management Co LLC | 103,177 | $3.49M | 0.55% | +103,177 | New |
| Rafferty Asset Management, LLC | 102,741 | $3.48M | 0.01% | −4,749−4.4% | Reduced |
| Tang Capital Management LLC | 100,000 | $3.38M | 0.17% | +100,000 | New |
| Knott David M Jr | 93,058 | $3.15M | 1.87% | +75,058+417.0% | Added |
| Trexquant Investment LP | 75,298 | $2.55M | 0.02% | −151,302−66.8% | Reduced |
| Woodline Partners LP | 74,423 | $2.52M | 0.01% | 00.0% | Unchanged |
| Rhumbline Advisers | 73,369 | $2.48M | 0.00% | −784−1.1% | Reduced |
| California State Teachers Retirement System | 68,564 | $2.32M | 0.00% | +15,325+28.8% | Added |
| Assenagon Asset Management S.A. | 67,153 | $2.27M | 0.00% | −43,287−39.2% | Reduced |
| SEI Investments Co | 63,550 | $2.15M | 0.00% | +49,198+342.8% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 60,679 | $2.05M | 0.00% | +119+0.2% | Added |
| Headlands Technologies LLC | 59,257 | $2.00M | 0.23% | +6,518+12.4% | Added |
| Vanguard Asset Management, Ltd | 58,648 | $1.98M | 0.00% | +58,648 | New |
| Tudor Investment Corp Et Al | 58,151 | $1.97M | 0.01% | −3,194−5.2% | Reduced |
| SG Americas Securities, LLC | 57,247 | $1.94M | 0.00% | +10,796+23.2% | Added |
| Barclays PLC | 52,438 | $1.77M | 0.00% | −267,914−83.6% | Reduced |
| Hudson Bay Capital Management LP | 51,830 | $1.75M | 0.01% | −48,170−48.2% | Reduced |
| New York State Common Retirement Fund | 51,707 | $1.75M | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 50,384 | $1.70M | 0.00% | −72,491−59.0% | Reduced |
| Manufacturers Life Insurance Company, The | 50,046 | $1.69M | 0.00% | −20,210−28.8% | Reduced |
| Alliancebernstein L.P. | 61,494 | $1.67M | 0.00% | 00.0% | Unchanged |
| Capital International Investors | 48,616 | $1.64M | 0.00% | −655,249−93.1% | Reduced |
| Alps Advisors Inc | 47,701 | $1.61M | 0.01% | −180−0.4% | Reduced |
| Profund Advisors LLC | 45,794 | $1.55M | 0.06% | +5,944+14.9% | Added |
| Harbor Capital Advisors, Inc. | 43,005 | $1.46M | 0.12% | +5,777+15.5% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 42,071 | $1.39M | 0.00% | +2,616+6.6% | Added |
| Russell Investments Group, Ltd. | 39,710 | $1.34M | 0.00% | +15,031+60.9% | Added |
| Virginia Retirement Systems Et Al | 39,061 | $1.32M | 0.01% | −2,300−5.6% | Reduced |
| Simplex Trading, LLC | 37,462 | $1.27M | 0.04% | +31,253+503.3% | Added |
| Gsa Capital Partners LLP | 36,472 | $1.23M | 0.08% | +36,472 | New |
| AQR Capital Management LLC | 36,410 | $1.23M | 0.00% | +8,484+30.4% | Added |
| Martingale Asset Management L P | 35,814 | $1.21M | 0.03% | +35,814 | New |