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Agios Pharmaceuticals, Inc.

AGIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001439222

In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Agios Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
221
−1 vs. Q4 2024
Shares held
60.1M
+417.7K (+0.7%) vs. Q4 2024
Total value
$1.76B
−$198.2M (−10.1%) vs. Q4 2024
New holders
38
73 more added
Sold out
39
78 more reduced

3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 221 institutions
Q1 2021: 175 institutionsQ2 2021: 186 institutionsQ3 2021: 165 institutionsQ4 2021: 161 institutionsQ1 2022: 161 institutionsQ2 2022: 157 institutionsQ3 2022: 168 institutionsQ4 2022: 160 institutionsQ1 2023: 165 institutionsQ2 2023: 153 institutionsQ3 2023: 146 institutionsQ4 2023: 170 institutionsQ1 2024: 187 institutionsQ2 2024: 206 institutionsQ3 2024: 208 institutionsQ4 2024: 225 institutionsQ1 2025: 221 institutionsQ2 2025: 216 institutionsQ3 2025: 221 institutionsQ4 2025: 238 institutionsQ1 2026: 234 institutionsQ2 2026: 238 institutions
Value heldQ1 2025: $1.76B
Q1 2021: $3.37BQ2 2021: $3.63BQ3 2021: $2.81BQ4 2021: $1.95BQ1 2022: $1.74BQ2 2022: $1.31BQ3 2022: $1.64BQ4 2022: $1.67BQ1 2023: $1.36BQ2 2023: $1.68BQ3 2023: $1.46BQ4 2023: $1.33BQ1 2024: $1.81BQ2 2024: $2.51BQ3 2024: $2.58BQ4 2024: $1.97BQ1 2025: $1.76BQ2 2025: $2.05BQ3 2025: $2.55BQ4 2025: $1.67BQ1 2026: $2.12BQ2 2026: $2.45B
Institutions holding AGIO and their total value by quarter
QuarterHoldersValue
Q2 2026238$2.45B
Q1 2026234$2.12B
Q4 2025238$1.67B
Q3 2025221$2.55B
Q2 2025216$2.05B
Q1 2025221$1.76B
Q4 2024225$1.97B
Q3 2024208$2.58B
Q2 2024206$2.51B
Q1 2024187$1.81B
Q4 2023170$1.33B
Q3 2023146$1.46B
Q2 2023153$1.68B
Q1 2023165$1.36B
Q4 2022160$1.67B
Q3 2022168$1.64B
Q2 2022157$1.31B
Q1 2022161$1.74B
Q4 2021161$1.95B
Q3 2021165$2.81B
Q2 2021186$3.63B
Q1 2021175$3.37B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q4 2024.

Institutions holding AGIO in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Farallon Capital Management, L.L.C.5,700,466$167.0M0.90%+26,000+0.5%Added
Vanguard Group Inc5,604,591$164.2M0.00%−26,730−0.5%Reduced
BlackRock, Inc.5,108,746$149.7M0.00%+92,486+1.8%Added
Bellevue Group AG3,515,150$103.0M2.31%00.0%Unchanged
State Street Corp2,449,479$71.8M0.00%+297,202+13.8%Added
Price T Rowe Associates Inc2,301,353$67.4M0.01%−122,184−5.0%Reduced
Erste Asset Management GmbH2,229,900$65.4M0.84%+220,000+10.9%Added
Commodore Capital LP2,185,000$64.0M4.72%+2,185,000New
Armistice Capital, LLC2,048,000$60.0M1.60%−216,304−9.6%Reduced
Macquarie Group Ltd1,850,544$54.2M0.07%+165,551+9.8%Added
Geode Capital Management, LLC1,394,581$40.9M0.00%+44,930+3.3%Added
Dimensional Fund Advisors LP1,262,073$37.0M0.01%−66,992−5.0%Reduced
Bank of America Corp1,135,592$33.3M0.00%+730,690+180.5%Added
Frazier Life Sciences Management, L.P.1,069,854$31.3M1.43%+1000.0%Added
JPMorgan Chase & Co1,049,360$30.7M0.00%+34,000+3.3%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,025,719$30.1M0.08%+83,530+8.9%Added
Polar Capital Holdings Plc1,002,036$29.4M0.18%+375,000+59.8%Added
Fisher Asset Management, LLC959,339$28.1M0.01%−1,322−0.1%Reduced
Deutsche Bank AG928,970$27.2M0.01%−6,282−0.7%Reduced
Citadel Advisors LLC863,499$25.3M0.02%−570,177−39.8%Reduced
ArrowMark Colorado Holdings LLC827,623$24.2M0.39%−89,797−9.8%Reduced
GW&K Investment Management, LLC817,526$24.0M0.22%+134,063+19.6%Added
Adage Capital Partners GP, L.L.C.743,000$21.8M0.04%+440,000+145.2%Added
Caligan Partners LP701,280$20.5M4.29%+75,000+12.0%Added
Goldman Sachs Group Inc658,652$19.3M0.00%+91,482+16.1%Added
SCS Capital Management LLC611,098$17.9M0.23%+611,098New
Northern Trust Corp576,258$16.9M0.00%−19,222−3.2%Reduced
D. E. Shaw & Co., Inc.554,820$16.3M0.02%+38,345+7.4%Added
Marshall Wace, LLP520,873$15.3M0.02%−110,755−17.5%Reduced
Charles Schwab Investment Management Inc464,958$13.6M0.00%−7,589−1.6%Reduced
Artisan Partners Limited Partnership410,672$12.0M0.02%−88,462−17.7%Reduced
Connor, Clark & Lunn Investment Management Ltd.386,523$11.3M0.05%+260,845+207.6%Added
Rock Springs Capital Management LP342,180$10.0M0.57%−128,906−27.4%Reduced
Voloridge Investment Management, LLC331,643$9.72M0.04%+131,162+65.4%Added
Eagle Health Investments LP330,830$9.69M2.52%00.0%Unchanged
OrbiMed Advisors LLC325,500$9.54M0.23%+298,800+1,119.1%Added
Pictet Asset Management Holding SA310,781$9.40M0.01%−43,674−12.3%Reduced
Morgan Stanley294,623$8.63M0.00%−83,466−22.1%Reduced
Palo Alto Investors LP276,578$8.10M1.54%+276,578New
Bank of New York Mellon Corp263,450$7.72M0.00%−2,064−0.8%Reduced
Boothbay Fund Management, LLC261,221$7.65M0.27%+9,447+3.8%Added
Casdin Capital, LLC250,000$7.33M0.60%00.0%Unchanged
Cutter Capital Management, LP235,350$6.90M3.00%−66,273−22.0%Reduced
AXA S.A.225,119$6.60M0.02%+49,742+28.4%Added
Nordea Investment Management AB224,173$6.51M0.01%+3,604+1.6%Added
Prudential Financial Inc204,242$5.98M0.01%+99,320+94.7%Added
TD Asset Management Inc178,072$5.22M0.00%+12,400+7.5%Added
Citigroup Inc176,128$5.16M0.00%−17,024−8.8%Reduced
Nuveen, LLC83,409$4.43M0.00%+83,409New
Walleye Capital LLC150,511$4.41M0.05%−49,027−24.6%Reduced
UBS Asset Management Americas Inc147,276$4.32M0.00%+24,441+19.9%Added
Patient Square Capital LP139,732$4.09M1.69%+18,000+14.8%Added
Granahan Investment Management Inc132,108$3.87M0.19%+16,421+14.2%Added
UBS Group AG131,642$3.86M0.00%−102,701−43.8%Reduced
Manufacturers Life Insurance Company, The131,571$3.86M0.00%+9,477+7.8%Added
Qube Research & Technologies Ltd127,980$3.75M0.01%−71,990−36.0%Reduced
Jane Street Group, LLC126,104$3.69M0.01%−87,923−41.1%Reduced
American Century Companies Inc114,947$3.37M0.00%+10,110+9.6%Added
Barclays PLC113,153$3.32M0.00%−8,600−7.1%Reduced
Hudson Bay Capital Management LP110,720$3.24M0.02%+720+0.7%Added
CenterBook Partners LP108,509$3.18M0.20%−197,090−64.5%Reduced
Invesco Ltd.107,367$3.15M0.00%+23,852+28.6%Added
Swiss National Bank99,460$2.91M0.00%−1,300−1.3%Reduced
Rafferty Asset Management, LLC93,627$2.74M0.01%+23,314+33.2%Added
Allianz Asset Management GmbH92,233$2.70M0.00%−26,347−22.2%Reduced
Rhumbline Advisers86,842$2.54M0.00%−7,666−8.1%Reduced
Silvercrest Asset Management Group LLC82,679$2.42M0.02%−478−0.6%Reduced
Susquehanna International Group, LLP81,962$2.40M0.00%−88,542−51.9%Reduced
Norges Bank77,544$2.27M0.00%−67,548−46.6%Reduced
Algert Global LLC74,810$2.19M0.05%+62,570+511.2%Added
Capital Fund Management S.A.72,302$2.12M0.03%+72,302New
Caption Management, LLC70,000$2.05M0.09%−34,404−33.0%Reduced
State of Wisconsin Investment Board69,684$2.04M0.01%+1,363+2.0%Added
Wells Fargo & Company68,137$2.00M0.00%+33,329+95.8%Added
Franklin Resources Inc68,072$1.99M0.00%+1,611+2.4%Added
Kennedy Capital Management, Inc.62,953$1.84M0.04%−48,145−43.3%Reduced
Alliancebernstein L.P.61,478$1.80M0.00%−220.0%Reduced
Legal & General Group Plc60,043$1.76M0.00%−11,634−16.2%Reduced
Moore Capital Management, LP60,000$1.76M0.06%00.0%Unchanged
UBS Oconnor LLC58,722$1.72M0.04%+15,392+35.5%Added
Universal- Beteiligungs- und Servicegesellschaft mbH54,651$1.60M0.00%+54,651New
Millennium Management LLC53,073$1.56M0.00%+30,877+139.1%Added
AQR Capital Management LLC51,489$1.50M0.00%+20,625+66.8%Added
Kodai Capital Management LP50,692$1.49M0.06%+50,692New
Panagora Asset Management Inc47,221$1.38M0.01%00.0%Unchanged
California State Teachers Retirement System46,988$1.38M0.00%−1,267−2.6%Reduced
Ameriprise Financial Inc46,811$1.37M0.00%+7,549+19.2%Added
HighVista Strategies LLC44,105$1.29M0.50%+44,105New
Mirae Asset Global ETFs Holdings Ltd.43,327$1.27M0.00%+2,920+7.2%Added
Alps Advisors Inc42,219$1.24M0.01%−3,892−8.4%Reduced
Gsa Capital Partners LLP41,029$1.20M0.11%−12,200−22.9%Reduced
DekaBank Deutsche Girozentrale40,000$1.19M0.00%00.0%Unchanged
Virginia Retirement Systems Et Al39,261$1.15M0.01%+39,261New
New York State Common Retirement Fund39,093$1.15M0.00%00.0%Unchanged
Oak Ridge Investments LLC39,087$1.15M0.10%+218+0.6%Added
Squarepoint Ops LLC37,920$1.11M0.00%−124,495−76.7%Reduced
First Trust Advisors LP37,330$1.09M0.00%−59,929−61.6%Reduced
Harbor Capital Advisors, Inc.35,729$1.05M0.05%+1,962+5.8%Added
Intech Investment Management LLC35,289$1.03M0.01%+7,041+24.9%Added
Edgewood Management LLC35,000$1.03M0.00%+5,000+16.7%Added