Agios Pharmaceuticals, Inc.
AGIO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001439222
In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Agios Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 221
- +8 vs. Q2 2025
- Shares held
- 63.5M
- +1.82M (+3.0%) vs. Q2 2025
- Total value
- $2.55B
- +$494.7M (+24.1%) vs. Q2 2025
- New holders
- 42
- 69 more added
- Sold out
- 34
- 69 more reduced
3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 238 | $2.45B |
| Q1 2026 | 234 | $2.12B |
| Q4 2025 | 238 | $1.67B |
| Q3 2025 | 221 | $2.55B |
| Q2 2025 | 216 | $2.05B |
| Q1 2025 | 221 | $1.76B |
| Q4 2024 | 225 | $1.97B |
| Q3 2024 | 208 | $2.58B |
| Q2 2024 | 206 | $2.51B |
| Q1 2024 | 187 | $1.81B |
| Q4 2023 | 170 | $1.33B |
| Q3 2023 | 146 | $1.46B |
| Q2 2023 | 153 | $1.68B |
| Q1 2023 | 165 | $1.36B |
| Q4 2022 | 160 | $1.67B |
| Q3 2022 | 168 | $1.64B |
| Q2 2022 | 157 | $1.31B |
| Q1 2022 | 161 | $1.74B |
| Q4 2021 | 161 | $1.95B |
| Q3 2021 | 165 | $2.81B |
| Q2 2021 | 186 | $3.63B |
| Q1 2021 | 175 | $3.37B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Farallon Capital Management, L.L.C. | 5,781,066 | $232.1M | 1.31% | +13,600+0.2% | Added |
| Vanguard Group Inc | 5,604,876 | $225.0M | 0.00% | −77,143−1.4% | Reduced |
| BlackRock, Inc. | 4,545,738 | $182.5M | 0.00% | −288,022−6.0% | Reduced |
| Bellevue Group AG | 3,714,736 | $149.1M | 3.10% | +124,586+3.5% | Added |
| Erste Asset Management GmbH | 2,764,900 | $108.6M | 1.05% | +438,411+18.8% | Added |
| Paradigm Biocapital Advisors LP | 2,673,555 | $107.3M | 3.18% | +1,531,044+134.0% | Added |
| Wellington Management Group LLP | 2,471,416 | $99.2M | 0.02% | +2,049,287+485.5% | Added |
| Commodore Capital LP | 2,338,287 | $93.9M | 4.58% | +13,287+0.6% | Added |
| State Street Corp | 2,262,712 | $90.8M | 0.00% | +311,599+16.0% | Added |
| Macquarie Group Ltd | 1,958,101 | $78.6M | 0.09% | +57,505+3.0% | Added |
| Price T Rowe Associates Inc | 1,656,938 | $66.5M | 0.01% | −617,311−27.1% | Reduced |
| TCG Crossover Management, LLC | 1,430,041 | $57.4M | 2.82% | +733,038+105.2% | Added |
| Geode Capital Management, LLC | 1,416,315 | $56.9M | 0.00% | +10,560+0.8% | Added |
| Frazier Life Sciences Management, L.P. | 1,279,754 | $51.4M | 1.54% | 00.0% | Unchanged |
| Caligan Partners LP | 1,131,205 | $45.4M | 6.30% | +59,947+5.6% | Added |
| Bank of America Corp | 1,130,000 | $45.4M | 0.00% | +9,692+0.9% | Added |
| Dimensional Fund Advisors LP | 1,021,201 | $41.0M | 0.01% | −84,892−7.7% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 987,339 | $39.6M | 0.10% | −29,552−2.9% | Reduced |
| Rock Springs Capital Management LP | 958,542 | $38.5M | 2.25% | −31,203−3.2% | Reduced |
| Deutsche Bank AG | 926,734 | $37.2M | 0.01% | +5,148+0.6% | Added |
| Fisher Asset Management, LLC | 870,145 | $34.9M | 0.01% | −7,395−0.8% | Reduced |
| GW&K Investment Management, LLC | 852,942 | $34.2M | 0.30% | −15,676−1.8% | Reduced |
| Goldman Sachs Group Inc | 804,766 | $32.3M | 0.00% | +156,705+24.2% | Added |
| Adage Capital Partners GP, L.L.C. | 800,000 | $32.1M | 0.05% | +9,000+1.1% | Added |
| Armistice Capital, LLC | 764,000 | $30.7M | 0.96% | −404,000−34.6% | Reduced |
| ArrowMark Colorado Holdings LLC | 679,922 | $27.3M | 0.51% | +21,231+3.2% | Added |
| SCS Capital Management LLC | 598,765 | $24.0M | 0.26% | −5,320−0.9% | Reduced |
| Northern Trust Corp | 555,410 | $22.3M | 0.00% | −1,395−0.3% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 530,098 | $21.3M | 0.07% | +24,873+4.9% | Added |
| Balyasny Asset Management LLC | 495,491 | $19.9M | 0.04% | +495,491 | New |
| Boothbay Fund Management, LLC | 495,341 | $19.9M | 0.51% | +48,322+10.8% | Added |
| Citadel Advisors LLC | 491,982 | $19.7M | 0.02% | −589,488−54.5% | Reduced |
| Charles Schwab Investment Management Inc | 482,186 | $19.4M | 0.00% | +6,145+1.3% | Added |
| Morgan Stanley | 416,998 | $16.7M | 0.00% | +125,033+42.8% | Added |
| Artisan Partners Limited Partnership | 402,943 | $16.2M | 0.02% | +12,959+3.3% | Added |
| Jane Street Group, LLC | 395,120 | $15.9M | 0.02% | +361,631+1,079.9% | Added |
| D. E. Shaw & Co., Inc. | 367,749 | $14.8M | 0.01% | −228,453−38.3% | Reduced |
| Legal & General Group Plc | 322,934 | $13.0M | 0.00% | +258,629+402.2% | Added |
| Bank of New York Mellon Corp | 270,096 | $10.8M | 0.00% | +3,442+1.3% | Added |
| Pictet Asset Management Holding SA | 272,161 | $10.7M | 0.01% | −22,579−7.7% | Reduced |
| Palo Alto Investors LP | 265,497 | $10.7M | 1.97% | −3,286−1.2% | Reduced |
| SummitTX Capital, L.P. | 262,977 | $10.6M | 0.44% | +262,977 | New |
| Eagle Health Investments LP | 246,230 | $9.88M | 2.59% | −84,600−25.6% | Reduced |
| UBS Group AG | 242,813 | $9.75M | 0.00% | +123,979+104.3% | Added |
| Marshall Wace, LLP | 226,824 | $9.10M | 0.01% | −457,845−66.9% | Reduced |
| Barclays PLC | 216,040 | $8.67M | 0.00% | +35,336+19.6% | Added |
| HighVista Strategies LLC | 195,298 | $7.84M | 1.92% | +125,171+178.5% | Added |
| Baker Bros. Advisors LP | 189,866 | $7.62M | 0.06% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 183,100 | $7.35M | 0.00% | −844,317−82.2% | Reduced |
| AXA Investment Managers S.A. | 177,675 | $7.13M | 0.02% | +177,675 | New |
| Peregrine Capital Management LLC | 162,905 | $6.54M | 0.20% | +162,905 | New |
| Allianz Asset Management GmbH | 146,643 | $5.89M | 0.01% | +7,745+5.6% | Added |
| Alyeska Investment Group, L.P. | 146,514 | $5.88M | 0.02% | +146,514 | New |
| American Century Companies Inc | 145,121 | $5.83M | 0.00% | +17,474+13.7% | Added |
| Patient Square Capital LP | 133,827 | $5.37M | 1.44% | −5,905−4.2% | Reduced |
| TD Asset Management Inc | 128,294 | $5.15M | 0.00% | −39,900−23.7% | Reduced |
| Vestal Point Capital, LP | 127,000 | $5.10M | 0.23% | +127,000 | New |
| Ikarian Capital, LLC | 126,979 | $5.10M | 1.16% | +126,979 | New |
| Invesco Ltd. | 126,976 | $5.10M | 0.00% | +14,359+12.8% | Added |
| Hudson Bay Capital Management LP | 122,500 | $4.92M | 0.03% | −7,500−5.8% | Reduced |
| Nuveen, LLC | 119,580 | $4.80M | 0.00% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 106,875 | $4.29M | 0.00% | −110,527−50.8% | Reduced |
| Swiss National Bank | 106,660 | $4.28M | 0.00% | −2,800−2.6% | Reduced |
| Parkman Healthcare Partners LLC | 100,380 | $4.03M | 0.44% | +100,380 | New |
| Nantahala Capital Management, LLC | 100,000 | $4.01M | 0.25% | +100,000 | New |
| Prudential Financial Inc | 98,239 | $3.94M | 0.00% | −60,120−38.0% | Reduced |
| Manufacturers Life Insurance Company, The | 96,012 | $3.85M | 0.00% | −36,071−27.3% | Reduced |
| AQR Capital Management LLC | 91,635 | $3.61M | 0.00% | −5,261−5.4% | Reduced |
| Jump Financial, LLC | 87,900 | $3.53M | 0.04% | +87,900 | New |
| Rhumbline Advisers | 87,702 | $3.52M | 0.00% | −2,179−2.4% | Reduced |
| First Trust Advisors LP | 74,429 | $2.99M | 0.00% | +38,002+104.3% | Added |
| Woodline Partners LP | 73,996 | $2.97M | 0.01% | −159,072−68.3% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 71,213 | $2.86M | 0.00% | +15,929+28.8% | Added |
| Rafferty Asset Management, LLC | 68,220 | $2.74M | 0.01% | +18,817+38.1% | Added |
| Assenagon Asset Management S.A. | 67,153 | $2.70M | 0.00% | +67,153 | New |
| Alliancebernstein L.P. | 61,503 | $2.47M | 0.00% | +33+0.1% | Added |
| California State Teachers Retirement System | 61,296 | $2.46M | 0.00% | +13,637+28.6% | Added |
| Two Sigma Investments, LP | 59,629 | $2.39M | 0.00% | +59,629 | New |
| Moore Capital Management, LP | 55,000 | $2.21M | 0.04% | −25,000−31.3% | Reduced |
| New York State Common Retirement Fund | 49,790 | $2.00M | 0.00% | +10,697+27.4% | Added |
| Phocas Financial Corp. | 46,608 | $1.87M | 0.24% | +46,608 | New |
| Wells Fargo & Company | 44,754 | $1.80M | 0.00% | +7,060+18.7% | Added |
| Citigroup Inc | 43,620 | $1.75M | 0.00% | −12,869−22.8% | Reduced |
| Virginia Retirement Systems Et Al | 41,061 | $1.65M | 0.01% | −8,600−17.3% | Reduced |
| DekaBank Deutsche Girozentrale | 40,000 | $1.56M | 0.00% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 38,428 | $1.54M | 0.00% | −13,824−26.5% | Reduced |
| ADAR1 Capital Management, LLC | 37,000 | $1.49M | 0.15% | +1,100+3.1% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 36,592 | $1.47M | 0.00% | −2,987−7.5% | Reduced |
| Algert Global LLC | 35,770 | $1.44M | 0.02% | −53,060−59.7% | Reduced |
| State of Wisconsin Investment Board | 35,573 | $1.43M | 0.00% | −23,527−39.8% | Reduced |
| Edgewood Management LLC | 35,000 | $1.40M | 0.00% | 00.0% | Unchanged |
| Harbor Capital Advisors, Inc. | 34,835 | $1.40M | 0.11% | −2,189−5.9% | Reduced |
| MetLife Investment Management | 34,032 | $1.37M | 0.01% | 00.0% | Unchanged |
| SEI Investments Co | 32,300 | $1.30M | 0.00% | +21,974+212.8% | Added |
| Victory Capital Management Inc | 30,232 | $1.21M | 0.00% | +818+2.8% | Added |
| SG Americas Securities, LLC | 27,650 | $1.11M | 0.00% | +27,650 | New |
| Alps Advisors Inc | 27,554 | $1.11M | 0.01% | −3,720−11.9% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 25,501 | $1.02M | 0.04% | +10,496+70.0% | Added |
| Oak Ridge Investments LLC | 25,385 | $1.02M | 0.07% | −11,867−31.9% | Reduced |
| Kennedy Capital Management, Inc. | 24,641 | $989.1K | 0.02% | −12,064−32.9% | Reduced |