Agios Pharmaceuticals, Inc.
AGIO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001439222
In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 1 sale; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Agios Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 221
- +8 vs. Q2 2025
- Shares held
- 63.5M
- +1.82M (+3.0%) vs. Q2 2025
- Total value
- $2.55B
- +$494.7M (+24.1%) vs. Q2 2025
- New holders
- 42
- 69 more added
- Sold out
- 34
- 69 more reduced
3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 238 | $2.45B |
| Q1 2026 | 234 | $2.12B |
| Q4 2025 | 238 | $1.67B |
| Q3 2025 | 221 | $2.55B |
| Q2 2025 | 216 | $2.05B |
| Q1 2025 | 221 | $1.76B |
| Q4 2024 | 225 | $1.97B |
| Q3 2024 | 208 | $2.58B |
| Q2 2024 | 206 | $2.51B |
| Q1 2024 | 187 | $1.81B |
| Q4 2023 | 170 | $1.33B |
| Q3 2023 | 146 | $1.46B |
| Q2 2023 | 153 | $1.68B |
| Q1 2023 | 165 | $1.36B |
| Q4 2022 | 160 | $1.67B |
| Q3 2022 | 168 | $1.64B |
| Q2 2022 | 157 | $1.31B |
| Q1 2022 | 161 | $1.74B |
| Q4 2021 | 161 | $1.95B |
| Q3 2021 | 165 | $2.81B |
| Q2 2021 | 186 | $3.63B |
| Q1 2021 | 175 | $3.37B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Janus Henderson Group PLC | 23,797 | $955.3K | 0.00% | 00.0% | Unchanged |
| Intech Investment Management LLC | 23,578 | $946.4K | 0.01% | +785+3.4% | Added |
| FMR LLC | 20,712 | $831.4K | 0.00% | +2,120+11.4% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 20,476 | $821.9K | 0.00% | +4,080+24.9% | Added |
| Great West Life Assurance Co | 20,325 | $796.0K | 0.00% | +662+3.4% | Added |
| Handelsbanken Fonder AB | 19,323 | $776.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 17,527 | $705.0K | 0.00% | −5,637−24.3% | Reduced |
| Caption Management, LLC | 17,494 | $702.2K | 0.04% | +494+2.9% | Added |
| Winton Group Ltd | 16,400 | $658.3K | 0.02% | +16,400 | New |
| Arizona State Retirement System | 16,255 | $652.5K | 0.00% | −421−2.5% | Reduced |
| Rockefeller Capital Management L.P. | 16,038 | $643.8K | 0.00% | +16,038 | New |
| Guggenheim Capital LLC | 15,902 | $638.3K | 0.00% | −2,002−11.2% | Reduced |
| State Board of Administration of Florida Retirement System | 15,847 | $636.1K | 0.00% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 15,633 | $627.5K | 0.01% | +2,710+21.0% | Added |
| Freestone Grove Partners LP | 15,424 | $619.1K | 0.00% | +15,424 | New |
| Profund Advisors LLC | 15,109 | $606.5K | 0.02% | +4,258+39.2% | Added |
| Toroso Investments, LLC | 14,914 | $598.6K | 0.00% | −646−4.2% | Reduced |
| BNP Paribas Arbitrage, SA | 14,698 | $590.0K | 0.00% | +2,790+23.4% | Added |
| Two Sigma Advisers, LP | 13,600 | $545.9K | 0.00% | +13,600 | New |
| Teacher Retirement System of Texas | 13,484 | $541.2K | 0.00% | −1,921−12.5% | Reduced |
| Atria Investments LLC | 13,386 | $537.3K | 0.01% | −87−0.6% | Reduced |
| Henshaw Capital LLC | 13,227 | $530.9K | 0.02% | −814−5.8% | Reduced |
| Creative Planning | 13,119 | $526.6K | 0.00% | +280+2.2% | Added |
| Virtus Investment Advisers, Inc. | 12,881 | $517.0K | 0.15% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 12,620 | $506.6K | 0.00% | −12,350−49.5% | Reduced |
| Brevan Howard Capital Management LP | 12,071 | $484.5K | 0.01% | −17,106−58.6% | Reduced |
| Savvy Advisors, Inc. | 11,993 | $481.4K | 0.02% | −9,788−44.9% | Reduced |
| KLP Kapitalforvaltning AS | 11,800 | $473.7K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 11,728 | $470.8K | 0.00% | −2,016−14.7% | Reduced |
| CWM Advisors, LLC | 11,395 | $457.4K | 0.04% | −333−2.8% | Reduced |
| Gallagher Fiduciary Advisors, LLC | 11,260 | $452.0K | 0.02% | −213−1.9% | Reduced |
| Omers Administration Corp | 11,200 | $449.6K | 0.00% | +11,200 | New |
| China Universal Asset Management Co., Ltd. | 10,184 | $408.8K | 0.03% | −1,448−12.4% | Reduced |
| Voya Investment Management LLC | 10,134 | $406.8K | 0.00% | −5,274−34.2% | Reduced |
| Cinctive Capital Management LP | 10,099 | $405.4K | 0.02% | +10,099 | New |
| Envestnet Asset Management Inc | 9,423 | $378.2K | 0.00% | −677−6.7% | Reduced |
| Commerce Bank | 9,159 | $367.6K | 0.00% | −445−4.6% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 7,932 | $318.4K | 0.01% | +7,932 | New |
| Russell Investments Group, Ltd. | 6,856 | $275.2K | 0.00% | −2,436−26.2% | Reduced |
| Public Employees Retirement Association of Colorado | 6,796 | $273.0K | 0.00% | 00.0% | Unchanged |
| Voleon Capital Management LP | 6,682 | $268.2K | 0.01% | +6,682 | New |
| Point72 Asset Management, L.P. | 6,507 | $261.2K | 0.00% | +6,507 | New |
| Cerity Partners LLC | 6,439 | $258.5K | 0.00% | −350−5.2% | Reduced |
| Cubist Systematic Strategies, LLC | 6,264 | $251.4K | 0.00% | +6,264 | New |
| CIBC Bancorp USA Inc. | 6,021 | $241.7K | 0.00% | +6,021 | New |
| Fiduciary Trust Co | 5,454 | $218.9K | 0.00% | +5,454 | New |
| Quest Partners LLC | 5,411 | $217.2K | 0.01% | +4,742+708.8% | Added |
| Northcape Wealth Management, LLC | 5,240 | $210.3K | 0.06% | +5,240 | New |
| Millennium Management LLC | 5,049 | $202.7K | 0.00% | −295,154−98.3% | Reduced |
| North Star Asset Management Inc | 5,000 | $200.7K | 0.01% | +5,000 | New |
| Quarry LP | 5,000 | $200.7K | 0.05% | +5,000 | New |
| CWM, LLC | 4,791 | $192.0K | 0.00% | −495−9.4% | Reduced |
| Ameritas Investment Partners, Inc. | 4,719 | $189.4K | 0.01% | −1,194−20.2% | Reduced |
| The PNC Financial Services Group, Inc. | 4,554 | $182.8K | 0.00% | +135+3.1% | Added |
| Sterling Capital Management LLC | 3,911 | $157.0K | 0.00% | +2,396+158.2% | Added |
| Torno Capital, LLC | 2,500 | $100.3K | 0.01% | +2,500 | New |
| Mirae Asset Global Investments Co., Ltd. | 2,246 | $90.2K | 0.00% | +9+0.4% | Added |
| Quantbot Technologies LP | 1,976 | $79.3K | 0.00% | +1,976 | New |
| Amalgamated Bank | 1,957 | $79.0K | 0.00% | 00.0% | Unchanged |
| KBC Group NV | 1,751 | $70.0K | 0.00% | 00.0% | Unchanged |
| BIT Capital GmbH | 1,571 | $63.1K | 0.00% | −659−29.6% | Reduced |
| Tower Research Capital LLC (TRC) | 1,357 | $54.5K | 0.00% | −5,083−78.9% | Reduced |
| GWM Advisors LLC | 1,273 | $51.1K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,250 | $50.2K | 0.00% | −210−14.4% | Reduced |
| First Horizon Corp | 1,124 | $45.1K | 0.00% | +1,124 | New |
| Assetmark, Inc | 955 | $38.3K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 780 | $31.3K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 702 | $28.2K | 0.00% | +689+5,300.0% | Added |
| US Bancorp | 569 | $22.8K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 513 | $20.6K | 0.00% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 398 | $15.6K | 0.00% | +231+138.3% | Added |
| Comerica Bank | 374 | $15.0K | 0.00% | +21+5.9% | Added |
| Hurley Capital, LLC | 366 | $14.7K | 0.01% | 00.0% | Unchanged |
| Aspect Partners, LLC | 361 | $14.5K | 0.01% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 350 | $14.0K | 0.00% | +350 | New |
| Advisor Group Holdings, Inc. | 336 | $13.5K | 0.00% | −11−3.2% | Reduced |
| Versant Capital Management, Inc | 316 | $12.7K | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 310 | $12.4K | 0.00% | +5+1.6% | Added |
| Bell Investment Advisors, Inc | 298 | $12.0K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 291 | $11.7K | 0.00% | 00.0% | Unchanged |
| NBC Securities, Inc. | 241 | $9.67K | 0.00% | −104−30.1% | Reduced |
| Spire Wealth Management | 230 | $9.23K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 206 | $8.27K | 0.00% | +23+12.6% | Added |
| Hillsdale Investment Management Inc. | 200 | $8.03K | 0.00% | 00.0% | Unchanged |
| Concord Wealth Partners | 200 | $8.03K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 204 | $8.00K | 0.00% | 00.0% | Unchanged |
| Bessemer Group Inc | 186 | $7.00K | 0.00% | +76+69.1% | Added |
| Farther Finance Advisors, LLC | 161 | $6.46K | 0.00% | +10+6.6% | Added |
| Essential Partners LLC | 115 | $4.62K | 0.00% | 00.0% | Unchanged |
| Root Financial Partners, LLC | 106 | $4.25K | 0.00% | +106 | New |
| Mather Group, LLC. | 95 | $3.81K | 0.00% | +95 | New |
| Private Wealth Management Group, LLC | 84 | $3.37K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 75 | $3.01K | 0.00% | −15−16.7% | Reduced |
| Covestor Ltd | 64 | $3.00K | 0.00% | +61+2,033.3% | Added |
| Larson Financial Group LLC | 74 | $2.97K | 0.00% | +74 | New |
| JPL Wealth Management, LLC | 70 | $2.81K | 0.00% | +70 | New |
| EverSource Wealth Advisors, LLC | 62 | $2.49K | 0.00% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 53 | $2.13K | 0.00% | −544−91.1% | Reduced |
| Halbert Hargrove Global Advisors, LLC | 47 | $1.89K | 0.00% | +47 | New |
| Parkside Financial Bank & Trust | 45 | $1.81K | 0.00% | 00.0% | Unchanged |