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Agios Pharmaceuticals, Inc.

AGIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001439222

In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 1 sale; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Agios Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
221
+8 vs. Q2 2025
Shares held
63.5M
+1.82M (+3.0%) vs. Q2 2025
Total value
$2.55B
+$494.7M (+24.1%) vs. Q2 2025
New holders
42
69 more added
Sold out
34
69 more reduced

3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 221 institutions
Q1 2021: 175 institutionsQ2 2021: 186 institutionsQ3 2021: 165 institutionsQ4 2021: 161 institutionsQ1 2022: 161 institutionsQ2 2022: 157 institutionsQ3 2022: 168 institutionsQ4 2022: 160 institutionsQ1 2023: 165 institutionsQ2 2023: 153 institutionsQ3 2023: 146 institutionsQ4 2023: 170 institutionsQ1 2024: 187 institutionsQ2 2024: 206 institutionsQ3 2024: 208 institutionsQ4 2024: 225 institutionsQ1 2025: 221 institutionsQ2 2025: 216 institutionsQ3 2025: 221 institutionsQ4 2025: 238 institutionsQ1 2026: 234 institutionsQ2 2026: 238 institutions
Value heldQ3 2025: $2.55B
Q1 2021: $3.37BQ2 2021: $3.63BQ3 2021: $2.81BQ4 2021: $1.95BQ1 2022: $1.74BQ2 2022: $1.31BQ3 2022: $1.64BQ4 2022: $1.67BQ1 2023: $1.36BQ2 2023: $1.68BQ3 2023: $1.46BQ4 2023: $1.33BQ1 2024: $1.81BQ2 2024: $2.51BQ3 2024: $2.58BQ4 2024: $1.97BQ1 2025: $1.76BQ2 2025: $2.05BQ3 2025: $2.55BQ4 2025: $1.67BQ1 2026: $2.12BQ2 2026: $2.45B
Institutions holding AGIO and their total value by quarter
QuarterHoldersValue
Q2 2026238$2.45B
Q1 2026234$2.12B
Q4 2025238$1.67B
Q3 2025221$2.55B
Q2 2025216$2.05B
Q1 2025221$1.76B
Q4 2024225$1.97B
Q3 2024208$2.58B
Q2 2024206$2.51B
Q1 2024187$1.81B
Q4 2023170$1.33B
Q3 2023146$1.46B
Q2 2023153$1.68B
Q1 2023165$1.36B
Q4 2022160$1.67B
Q3 2022168$1.64B
Q2 2022157$1.31B
Q1 2022161$1.74B
Q4 2021161$1.95B
Q3 2021165$2.81B
Q2 2021186$3.63B
Q1 2021175$3.37B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q2 2025.

Institutions holding AGIO in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Raffa Wealth Management, LLC32$1.28K0.00%00.0%Unchanged
Fifth Third Bancorp30$1.20K0.00%+30New
MAI Capital Management25$1.00K0.00%−9−26.5%Reduced
Allworth Financial LP17$6830.00%+2+13.3%Added
JFS Wealth Advisors, LLC16$6430.00%00.0%Unchanged
Quadrant Capital Group LLC16$6430.00%+16New
Parallel Advisors, LLC12$4820.00%00.0%Unchanged
True Wealth Design, LLC9$3620.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC9$3610.00%00.0%Unchanged
IFP Advisors, Inc6$2410.00%+6Added
Wealthspire Advisors, LLC6$2410.00%+6New
Fortitude Family Office, LLC5$2010.00%00.0%Unchanged
SBI Securities Co., Ltd.4$1610.00%+1+33.3%Added
Bay Harbor Wealth Management, LLC3$1200.00%+1+50.0%Added
HFM Investment Advisors, LLC3$1200.00%+2+200.0%Added
Rialto Wealth Management, LLC2$810.00%00.0%Unchanged
SJS Investment Consulting Inc.2$810.00%+1+100.0%Added
Jones Financial Companies LLLP1$390.00%00.0%Unchanged
DiNuzzo Private Wealth, Inc.1$380.00%00.0%Unchanged
Hemington Wealth Management15$00.00%+9+150.0%Added
Cloud Capital Management, LLC1$00.00%+1New
OrbiMed Advisors LLC0$00.00%−557,900−100.0%Sold out
CenterBook Partners LP0$00.00%−243,063−100.0%Sold out
Nordea Investment Management AB0$00.00%−224,746−100.0%Sold out
AXA S.A.0$00.00%−225,367−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−187,395−100.0%Sold out
Cantor Fitzgerald, L. P.0$00.00%−134,200−100.0%Sold out
Casdin Capital, LLC0$00.00%−100,000−100.0%Sold out
Trexquant Investment LP0$00.00%−98,401−100.0%Sold out
Silvercrest Asset Management Group LLC0$00.00%−82,679−100.0%Sold out
Capital Fund Management S.A.0$00.00%−68,502−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−68,103−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−67,379−100.0%Sold out
UBS Oconnor LLC0$00.00%−56,810−100.0%Sold out
Franklin Resources Inc0$00.00%−50,108−100.0%Sold out
Panagora Asset Management Inc0$00.00%−47,190−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−46,346−100.0%Sold out
Granahan Investment Management Inc0$00.00%−41,886−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−17,707−100.0%Sold out
Thrivent Financial for Lutherans0$00.00%−17,526−100.0%Sold out
Engineers Gate Manager LP0$00.00%−16,548−100.0%Sold out
Centiva Capital, LP0$00.00%−15,040−100.0%Sold out
Polar Asset Management Partners Inc.0$00.00%−14,700−100.0%Sold out
Headlands Technologies LLC0$00.00%−12,644−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−8,646−100.0%Sold out
Ieq Capital, LLC0$00.00%−8,086−100.0%Sold out
Jain Global LLC0$00.00%−7,749−100.0%Sold out
Bryn Mawr Trust Co0$00.00%−1,885−100.0%Sold out
Skopos Labs, Inc.0$00.00%−1,130−100.0%Sold out
STRS Ohio0$00.00%−1,100−100.0%Sold out
Lazard Asset Management LLC0$00.00%−534−100.0%Sold out
Raymond James Financial Inc0$00.00%−442−100.0%Sold out
Kestra Investment Management, LLC0$00.00%−278−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−21−100.0%Sold out
Riggs Asset Managment Co. Inc.0$00.00%−3−100.0%Sold out
CIBC World Markets Corp––––Not filed
Norges Bank––––Not filed
First Horizon Advisors, Inc.––––Not filed