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Agios Pharmaceuticals, Inc.

AGIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001439222

In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Agios Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
161
−4 vs. Q3 2021
Shares held
59.2M
−1.69M (−2.8%) vs. Q3 2021
Total value
$1.95B
−$863.3M (−30.7%) vs. Q3 2021
New holders
28
47 more added
Sold out
32
61 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 161 institutions
Q1 2021: 175 institutionsQ2 2021: 186 institutionsQ3 2021: 165 institutionsQ4 2021: 161 institutionsQ1 2022: 161 institutionsQ2 2022: 157 institutionsQ3 2022: 168 institutionsQ4 2022: 160 institutionsQ1 2023: 165 institutionsQ2 2023: 153 institutionsQ3 2023: 146 institutionsQ4 2023: 170 institutionsQ1 2024: 187 institutionsQ2 2024: 206 institutionsQ3 2024: 208 institutionsQ4 2024: 225 institutionsQ1 2025: 221 institutionsQ2 2025: 216 institutionsQ3 2025: 221 institutionsQ4 2025: 238 institutionsQ1 2026: 234 institutionsQ2 2026: 238 institutions
Value heldQ4 2021: $1.95B
Q1 2021: $3.37BQ2 2021: $3.63BQ3 2021: $2.81BQ4 2021: $1.95BQ1 2022: $1.74BQ2 2022: $1.31BQ3 2022: $1.64BQ4 2022: $1.67BQ1 2023: $1.36BQ2 2023: $1.68BQ3 2023: $1.46BQ4 2023: $1.33BQ1 2024: $1.81BQ2 2024: $2.51BQ3 2024: $2.58BQ4 2024: $1.97BQ1 2025: $1.76BQ2 2025: $2.05BQ3 2025: $2.55BQ4 2025: $1.67BQ1 2026: $2.12BQ2 2026: $2.45B
Institutions holding AGIO and their total value by quarter
QuarterHoldersValue
Q2 2026238$2.45B
Q1 2026234$2.12B
Q4 2025238$1.67B
Q3 2025221$2.55B
Q2 2025216$2.05B
Q1 2025221$1.76B
Q4 2024225$1.97B
Q3 2024208$2.58B
Q2 2024206$2.51B
Q1 2024187$1.81B
Q4 2023170$1.33B
Q3 2023146$1.46B
Q2 2023153$1.68B
Q1 2023165$1.36B
Q4 2022160$1.67B
Q3 2022168$1.64B
Q2 2022157$1.31B
Q1 2022161$1.74B
Q4 2021161$1.95B
Q3 2021165$2.81B
Q2 2021186$3.63B
Q1 2021175$3.37B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q3 2021.

Institutions holding AGIO in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
The PNC Financial Services Group, Inc.41$00.00%−8−16.3%Reduced
Parallel Advisors, LLC9$00.00%−44−83.0%Reduced
Captrust Financial Advisors8$00.00%−24−75.0%Reduced
Earnest Partners LLC8$00.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC9$00.00%00.0%Unchanged
CWM, LLC7$00.00%+7New
JFS Wealth Advisors, LLC2$00.00%+2New
Schubert & Co2$00.00%+2New
Quadrant Capital Group LLC39$1.00K0.00%−58−59.8%Reduced
Signaturefd, LLC45$1.00K0.00%−28−38.4%Reduced
Tarbox Family Office, Inc.22$1.00K0.00%00.0%Unchanged
Princeton Global Asset Management LLC29$1.00K0.00%00.0%Unchanged
First Horizon Advisors, Inc.34$1.00K0.00%+22+183.3%Added
Lee Financial Co30$1.00K0.00%+30New
Tilia Fiduciary Partners, Inc.38$1.00K0.00%+38New
Raffa Wealth Management, LLC32$1.05K0.00%00.0%Unchanged
American Portfolios Advisors45$1.48K0.00%00.0%Unchanged
Standard Family Office LLC49$2.00K0.02%+49New
Lindbrook Capital, LLC96$3.00K0.00%−39−28.9%Reduced
Canada Pension Plan Investment Board121$4.00K0.00%−606−83.4%Reduced
North Star Investment Management Corp.125$4.00K0.00%+125New
Leonteq Securities AG142$4.67K0.00%+142New
Federated Hermes, Inc.140$5.00K0.00%−20,432−99.3%Reduced
Daiwa Securities Group Inc.158$5.00K0.00%−44−21.8%Reduced
Valley National Advisers Inc157$5.00K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.174$5.00K0.00%+174New
Baillie Gifford & Co186$6.00K0.00%00.0%Unchanged
TCI Wealth Advisors, Inc.193$6.00K0.00%+193New
Bell Investment Advisors, Inc213$7.00K0.00%+131+159.8%Added
Concord Wealth Partners200$7.00K0.00%+200New
Norway Savings Bank265$9.00K0.00%00.0%Unchanged
Spire Wealth Management288$9.00K0.00%+243+540.0%Added
Patriot Financial Group Insurance Agency, LLC350$12.0K0.00%+200+133.3%Added
Advisor Group Holdings, Inc.585$20.0K0.00%−261−30.9%Reduced
US Bancorp660$22.0K0.00%−1,067−61.8%Reduced
Quantbot Technologies LP900$29.0K0.00%+740+462.5%Added
Harbor Investment Advisory, LLC924$30.0K0.00%00.0%Unchanged
AdvisorNet Financial, Inc1,530$50.0K0.00%00.0%Unchanged
Point72 Hong Kong Ltd1,513$50.0K0.00%+1,032+214.6%Added
Nisa Investment Advisors, LLC1,710$53.0K0.00%−1,120−39.6%Reduced
Lazard Asset Management LLC2,125$69.0K0.00%+12+0.6%Added
Great West Life Assurance Co2,809$92.0K0.00%−456−14.0%Reduced
DekaBank Deutsche Girozentrale2,800$94.0K0.00%−33,900−92.4%Reduced
Amundi3,264$104.0K0.00%00.0%Unchanged
Walleye Trading LLC3,655$120.0K0.00%+3,655New
Ameritas Investment Partners, Inc.4,200$138.0K0.00%−321−7.1%Reduced
Simplex Trading, LLC4,260$140.0K0.00%−1,455−25.5%Reduced
Cutler Group LP4,972$163.0K0.01%00.0%Unchanged
Massachusetts Financial Services Co6,116$201.0K0.00%−124−2.0%Reduced
Two Sigma Advisers, LP6,400$210.0K0.00%+6,400New
Zurcher Kantonalbank (Zurich Cantonalbank)6,731$221.0K0.00%00.0%Unchanged
Connacht Asset Management LP7,133$234.0K0.27%+7,133New
Amalgamated Bank7,294$240.0K0.00%−424−5.5%Reduced
Profund Advisors LLC9,307$306.0K0.01%−1,982−17.6%Reduced
Neuberger Berman Group LLC9,670$317.0K0.00%−18,637−65.8%Reduced
Teacher Retirement System of Texas10,157$334.0K0.00%+1,378+15.7%Added
Dynamic Technology Lab Private Ltd10,190$335.0K0.04%+10,190New
Public Employees Retirement Association of Colorado10,796$355.0K0.00%00.0%Unchanged
Public Employees Retirement System of Ohio11,120$366.0K0.00%+2,120+23.6%Added
ExodusPoint Capital Management, LP11,172$367.0K0.00%−13,806−55.3%Reduced
Prudential Financial Inc11,215$369.0K0.00%−8,882−44.2%Reduced
Schonfeld Strategic Advisors LLC11,300$371.0K0.00%+11,300New
AlphaCentric Advisors LLC11,500$378.0K0.11%+11,500New
Virtus ETF Advisers LLC11,541$379.0K0.14%+3,692+47.0%Added
Handelsbanken Fonder AB11,723$385.0K0.00%00.0%Unchanged
Ensign Peak Advisors, Inc12,180$400.0K0.00%+12,180New
Victory Capital Management Inc12,227$402.0K0.00%−40,899−77.0%Reduced
Janus Henderson Group PLC12,694$418.0K0.00%+6,374+100.9%Added
Tower Research Capital LLC (TRC)13,063$429.0K0.01%+8,921+215.4%Added
ETF Managers Group, LLC13,233$444.0K0.01%+630+5.0%Added
Arizona State Retirement System14,280$469.0K0.00%−815−5.4%Reduced
Marshall Wace, LLP14,581$479.0K0.00%+14,581New
Metropolitan Life Insurance Co15,565$511.6K0.01%00.0%Unchanged
Winton Group Ltd18,756$617.0K0.04%−11,756−38.5%Reduced
Citadel Advisors LLC20,229$665.0K0.00%−78,253−79.5%Reduced
MetLife Investment Management20,321$668.0K0.01%00.0%Unchanged
Hennion & Walsh Asset Management, Inc.20,515$674.0K0.03%+1,283+6.7%Added
ProShare Advisors LLC20,882$687.0K0.00%−664−3.1%Reduced
International Biotechnology Trust PLC21,500$707.0K0.16%00.0%Unchanged
Voya Investment Management LLC22,095$726.0K0.00%−1,132−4.9%Reduced
State Board of Administration of Florida Retirement System24,587$808.0K0.00%00.0%Unchanged
Virginia Retirement Systems Et Al26,600$874.0K0.01%−4,400−14.2%Reduced
Manufacturers Life Insurance Company, The28,161$936.0K0.00%−2,525−8.2%Reduced
Royal Bank of Canada28,565$940.0K0.00%−1,967−6.4%Reduced
American International Group, Inc.28,876$949.0K0.00%−3,407−10.6%Reduced
AlphaCrest Capital Management LLC28,931$951.0K0.04%+12,207+73.0%Added
Invesco Ltd.33,133$1.09M0.00%−4,691−12.4%Reduced
Skandinaviska Enskilda Banken AB (publ)32,545$1.09M0.01%00.0%Unchanged
Qube Research & Technologies Ltd34,241$1.13M0.01%+34,241New
Allspring Global Investments Holdings, LLC34,289$1.13M0.00%+34,289New
BNP Paribas Arbitrage, SA35,601$1.17M0.00%+7,879+28.4%Added
HRT Financial LP38,805$1.27M0.01%+38,805New
Caption Management, LLC41,000$1.35M0.08%+41,000New
New York State Common Retirement Fund41,699$1.37M0.00%−7,667−15.5%Reduced
Alaska Permanent Fund Corp44,700$1.38M0.03%00.0%Unchanged
Squarepoint Ops LLC42,629$1.40M0.01%+42,629New
Voloridge Investment Management, LLC45,079$1.48M0.01%+27,640+158.5%Added
SG Americas Securities, LLC46,263$1.52M0.01%+9,663+26.4%Added
Legal & General Group Plc48,459$1.59M0.00%−894−1.8%Reduced
Parametric Portfolio Associates LLC49,475$1.63M0.00%−25,649−34.1%Reduced