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Agios Pharmaceuticals, Inc.

AGIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001439222

In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 1 sale; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Agios Pharmaceuticals, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of AGIO: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders2214238+21
Shares63.5M190.0K61.3M−2.05M (−3.2%)
Value$2.55B$7.62M$1.67B−$870.9M (−34.3%)

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (65)

Institutions that held Agios Pharmaceuticals, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to AGIO in Q4 2025
InstitutionSharesValue% of portfolio
Nomura Asset Management International Inc.1,701,409$46.3M0.07%
MPM Oncology Impact Management LP1,303,373$35.5M4.06%
Susquehanna International Group, LLP1,142,432$31.1M0.04%
Capital International Investors703,865$19.2M0.00%
Foresite Capital Management VI LLC530,000$14.4M4.36%
Qube Research & Technologies Ltd378,373$10.3M0.01%
Trexquant Investment LP226,600$6.17M0.05%
Edgestream Partners, L.P.167,998$4.57M0.13%
Group One Trading, L.P.166,614$4.54M0.13%
Polygon Management Ltd.162,018$4.41M0.93%
HRT Financial LP146,469$3.99M0.01%
Exome Asset Management LLC136,942$3.73M1.84%
Squarepoint Ops LLC121,763$3.31M0.01%
Jacobs Levy Equity Management, Inc111,150$3.03M0.01%
Panagora Asset Management Inc79,840$2.17M0.01%
Lynx1 Capital Management LP79,624$2.17M0.44%
ExodusPoint Capital Management, LP71,146$1.94M0.02%
Tudor Investment Corp Et Al61,345$1.67M0.01%
Headlands Technologies LLC52,739$1.44M0.12%
Engineers Gate Manager LP49,128$1.34M0.02%
State of New Jersey Common Pension Fund D47,414$1.29M0.00%
Schroder Investment Management Group46,242$1.26M0.00%
XTX Topco Ltd46,039$1.25M0.03%
Aquatic Capital Management LLC36,006$980.1K0.03%
Quadrature Capital Ltd35,857$976.0K0.01%
Capital Fund Management S.A.35,788$974.1K0.01%
Prelude Capital Management, LLC33,685$916.9K0.07%
Seven Fleet Capital Management LP31,738$863.9K0.58%
Ishara Investments LP30,000$816.6K0.95%
Quantinno Capital Management LP26,855$731.0K0.00%
Aigen Investment Management, LP25,915$705.4K0.16%
Entropy Technologies, LP19,163$521.6K0.03%
VARCOV Co.19,104$520.0K0.21%
Canada Pension Plan Investment Board18,200$495.4K0.00%
Knott David M Jr18,000$490.0K0.23%
AlphaCentric Advisors LLC13,141$357.7K0.36%
Bridgefront Capital, LLC12,649$344.3K0.09%
Fox Run Management, L.L.C.12,567$342.1K0.05%
Nomura Holdings Inc12,355$336.3K0.00%
Pale Fire Capital SE11,850$322.6K0.04%
Capstone Investment Advisors, LLC10,355$281.9K0.00%
STRS Ohio10,000$272.2K0.00%
Two Sigma Securities, LLC9,198$250.4K0.03%
Diversified Trust Co9,162$249.4K0.00%
Inscription Capital, LLC8,595$234.0K0.02%
Campbell & CO Investment Adviser LLC8,226$223.9K0.01%
Griffin Asset Management, Inc.7,382$200.9K0.02%
Caitong International Asset Management Co., Ltd6,740$183.5K0.04%
Simplex Trading, LLC6,209$169.0K0.00%
Contravisory Investment Management, Inc.6,189$168.5K0.03%
State of Alaska, Department of Revenue5,000$136.0K0.00%
Eurizon Capital SGR S.p.A.2,647$72.3K0.00%
T. Rowe Price Investment Management, Inc.892$25.0K0.00%
Torren Management, LLC615$16.7K0.01%
City Holding Co500$13.6K0.00%
Los Angeles Capital Management LLC300$13.0K0.00%
Thurston, Springer, Miller, Herd & Titak, Inc.241$6.56K0.00%
Brown Brothers Harriman & Co144$3.92K0.00%
Triumph Capital Management100$2.72K0.00%
Pinnacle Wealth Planning Services, Inc.40$1.09K0.00%
Keating Financial Advisory Services, Inc.21$5720.00%
Manchester Capital Management LLC16$4360.00%
Global Retirement Partners, LLC11$2990.00%
SageView Advisory Group, LLC10$2730.00%
Dunhill Financial, LLC2$500.00%

Sold out (44)

Institutions that held Agios Pharmaceuticals, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of AGIO in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Bellevue Group AG3,714,736$149.1M
Paradigm Biocapital Advisors LP2,673,555$107.3M
Commodore Capital LP2,338,287$93.9M
Macquarie Group Ltd1,958,101$78.6M
Caligan Partners LP1,131,205$45.4M
Fisher Asset Management, LLC870,145$34.9M
Adage Capital Partners GP, L.L.C.800,000$32.1M
SummitTX Capital, L.P.262,977$10.6M
Eagle Health Investments LP246,230$9.88M
Baker Bros. Advisors LP189,866$7.62M
Peregrine Capital Management LLC162,905$6.54M
Alyeska Investment Group, L.P.146,514$5.88M
Patient Square Capital LP133,827$5.37M
Nantahala Capital Management, LLC100,000$4.01M
Phocas Financial Corp.46,608$1.87M
Ameriprise Financial Inc38,428$1.54M
Guggenheim Capital LLC15,902$638.3K
Henshaw Capital LLC13,227$530.9K
Savvy Advisors, Inc.11,993$481.4K
Omers Administration Corp11,200$449.6K
Cinctive Capital Management LP10,099$405.4K
Voleon Capital Management LP6,682$268.2K
Cerity Partners LLC6,439$258.5K
Northcape Wealth Management, LLC5,240$210.3K
North Star Asset Management Inc5,000$200.7K
Torno Capital, LLC2,500$100.3K
BIT Capital GmbH1,571$63.1K
GWM Advisors LLC1,273$51.1K
Advisory Services Network, LLC350$14.0K
Optiver Holding B.V.310$12.4K
Clearstead Advisors, LLC291$11.7K
NBC Securities, Inc.241$9.67K
Spire Wealth Management230$9.23K
Mather Group, LLC.95$3.81K
Larson Financial Group LLC74$2.97K
JPL Wealth Management, LLC70$2.81K
Halbert Hargrove Global Advisors, LLC47$1.89K
Fifth Third Bancorp30$1.20K
MAI Capital Management25$1.00K
True Wealth Design, LLC9$362
Wealthspire Advisors, LLC6$241
HFM Investment Advisors, LLC3$120
DiNuzzo Private Wealth, Inc.1$38
Cloud Capital Management, LLC1$0

Not filed for Q4 2025 yet (4)

Institutions that held Agios Pharmaceuticals, Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding AGIO in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
AXA Investment Managers S.A.177,675$7.13M
Cubist Systematic Strategies, LLC6,264$251.4K
CIBC Bancorp USA Inc.6,021$241.7K
Hemington Wealth Management15$0