Agios Pharmaceuticals, Inc.
AGIO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001439222
In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Agios Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 238
- +21 vs. Q3 2025
- Shares held
- 61.3M
- −2.05M (−3.2%) vs. Q3 2025
- Total value
- $1.67B
- −$870.9M (−34.3%) vs. Q3 2025
- New holders
- 65
- 79 more added
- Sold out
- 44
- 70 more reduced
4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 238 | $2.45B |
| Q1 2026 | 234 | $2.12B |
| Q4 2025 | 238 | $1.67B |
| Q3 2025 | 221 | $2.55B |
| Q2 2025 | 216 | $2.05B |
| Q1 2025 | 221 | $1.76B |
| Q4 2024 | 225 | $1.97B |
| Q3 2024 | 208 | $2.58B |
| Q2 2024 | 206 | $2.51B |
| Q1 2024 | 187 | $1.81B |
| Q4 2023 | 170 | $1.33B |
| Q3 2023 | 146 | $1.46B |
| Q2 2023 | 153 | $1.68B |
| Q1 2023 | 165 | $1.36B |
| Q4 2022 | 160 | $1.67B |
| Q3 2022 | 168 | $1.64B |
| Q2 2022 | 157 | $1.31B |
| Q1 2022 | 161 | $1.74B |
| Q4 2021 | 161 | $1.95B |
| Q3 2021 | 165 | $2.81B |
| Q2 2021 | 186 | $3.63B |
| Q1 2021 | 175 | $3.37B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Jones Financial Companies LLLP | 1 | $27 | 0.00% | 00.0% | Unchanged |
| SJS Investment Consulting Inc. | 1 | $28 | 0.00% | −1−50.0% | Reduced |
| Dunhill Financial, LLC | 2 | $50 | 0.00% | +2 | New |
| Rialto Wealth Management, LLC | 2 | $55 | 0.00% | 00.0% | Unchanged |
| Bay Harbor Wealth Management, LLC | 4 | $108 | 0.00% | +1+33.3% | Added |
| JFS Wealth Advisors, LLC | 4 | $109 | 0.00% | −12−75.0% | Reduced |
| SBI Securities Co., Ltd. | 4 | $109 | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 5 | $136 | 0.00% | −110−95.7% | Reduced |
| Rothschild Investment LLC | 5 | $136 | 0.00% | −70−93.3% | Reduced |
| Fortitude Family Office, LLC | 5 | $136 | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 6 | $163 | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 9 | $245 | 0.00% | 00.0% | Unchanged |
| SageView Advisory Group, LLC | 10 | $273 | 0.00% | +10 | New |
| Global Retirement Partners, LLC | 11 | $299 | 0.00% | +11 | New |
| Allworth Financial LP | 11 | $300 | 0.00% | −6−35.3% | Reduced |
| Parallel Advisors, LLC | 12 | $327 | 0.00% | 00.0% | Unchanged |
| Parkside Financial Bank & Trust | 15 | $409 | 0.00% | −30−66.7% | Reduced |
| Quadrant Capital Group LLC | 16 | $436 | 0.00% | 00.0% | Unchanged |
| Manchester Capital Management LLC | 16 | $436 | 0.00% | +16 | New |
| Keating Financial Advisory Services, Inc. | 21 | $572 | 0.00% | +21 | New |
| Raffa Wealth Management, LLC | 32 | $871 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 34 | $926 | 0.00% | −28−45.2% | Reduced |
| Covestor Ltd | 41 | $1.00K | 0.00% | −23−35.9% | Reduced |
| Pinnacle Wealth Planning Services, Inc. | 40 | $1.09K | 0.00% | +40 | New |
| Root Financial Partners, LLC | 66 | $1.80K | 0.00% | −40−37.7% | Reduced |
| Bessemer Group Inc | 76 | $2.00K | 0.00% | −110−59.1% | Reduced |
| SRS Capital Advisors, Inc. | 79 | $2.15K | 0.00% | −623−88.7% | Reduced |
| Private Wealth Management Group, LLC | 83 | $2.26K | 0.00% | −1−1.2% | Reduced |
| Versant Capital Management, Inc | 92 | $2.50K | 0.00% | −224−70.9% | Reduced |
| Triumph Capital Management | 100 | $2.72K | 0.00% | +100 | New |
| Brown Brothers Harriman & Co | 144 | $3.92K | 0.00% | +144 | New |
| Farther Finance Advisors, LLC | 151 | $4.11K | 0.00% | −10−6.2% | Reduced |
| GAMMA Investing LLC | 171 | $4.66K | 0.00% | −35−17.0% | Reduced |
| Hillsdale Investment Management Inc. | 200 | $5.44K | 0.00% | 00.0% | Unchanged |
| Concord Wealth Partners | 200 | $5.44K | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 209 | $5.70K | 0.00% | −165−44.1% | Reduced |
| Daiwa Securities Group Inc. | 204 | $6.00K | 0.00% | 00.0% | Unchanged |
| Thurston, Springer, Miller, Herd & Titak, Inc. | 241 | $6.56K | 0.00% | +241 | New |
| Bell Investment Advisors, Inc | 281 | $7.65K | 0.00% | −17−5.7% | Reduced |
| Nisa Investment Advisors, LLC | 295 | $8.03K | 0.00% | −485−62.2% | Reduced |
| Aspect Partners, LLC | 361 | $9.83K | 0.00% | 00.0% | Unchanged |
| Quantbot Technologies LP | 386 | $10.5K | 0.00% | −1,590−80.5% | Reduced |
| Signaturefd, LLC | 399 | $10.9K | 0.00% | −114−22.2% | Reduced |
| Smartleaf Asset Management LLC | 460 | $12.6K | 0.00% | +62+15.6% | Added |
| Los Angeles Capital Management LLC | 300 | $13.0K | 0.00% | +300 | New |
| CWM, LLC | 484 | $13.0K | 0.00% | −4,307−89.9% | Reduced |
| Hurley Capital, LLC | 486 | $13.2K | 0.01% | +120+32.8% | Added |
| City Holding Co | 500 | $13.6K | 0.00% | +500 | New |
| US Bancorp | 509 | $13.9K | 0.00% | −60−10.5% | Reduced |
| Torren Management, LLC | 615 | $16.7K | 0.01% | +615 | New |
| T. Rowe Price Investment Management, Inc. | 892 | $25.0K | 0.00% | +892 | New |
| GF Fund Management Co. Ltd. | 1,145 | $31.2K | 0.00% | −105−8.4% | Reduced |
| Assetmark, Inc | 1,317 | $35.8K | 0.00% | +362+37.9% | Added |
| Advisor Group Holdings, Inc. | 1,747 | $47.6K | 0.00% | +1,411+419.9% | Added |
| Amalgamated Bank | 1,774 | $48.0K | 0.00% | −183−9.4% | Reduced |
| Eurizon Capital SGR S.p.A. | 2,647 | $72.3K | 0.00% | +2,647 | New |
| Mirae Asset Global Investments Co., Ltd. | 2,834 | $77.1K | 0.00% | +588+26.2% | Added |
| Quarry LP | 3,000 | $81.7K | 0.01% | −2,000−40.0% | Reduced |
| KBC Group NV | 3,020 | $82.0K | 0.00% | +1,269+72.5% | Added |
| First Horizon Corp | 3,095 | $84.2K | 0.00% | +1,971+175.4% | Added |
| Sterling Capital Management LLC | 3,283 | $89.4K | 0.00% | −628−16.1% | Reduced |
| The PNC Financial Services Group, Inc. | 4,710 | $128.2K | 0.00% | +156+3.4% | Added |
| Ameritas Investment Partners, Inc. | 4,719 | $128.5K | 0.00% | 00.0% | Unchanged |
| State of Alaska, Department of Revenue | 5,000 | $136.0K | 0.00% | +5,000 | New |
| Contravisory Investment Management, Inc. | 6,189 | $168.5K | 0.03% | +6,189 | New |
| Simplex Trading, LLC | 6,209 | $169.0K | 0.00% | +6,209 | New |
| Ensign Peak Advisors, Inc | 6,570 | $178.8K | 0.00% | −6,050−47.9% | Reduced |
| Tower Research Capital LLC (TRC) | 6,634 | $180.6K | 0.00% | +5,277+388.9% | Added |
| Caitong International Asset Management Co., Ltd | 6,740 | $183.5K | 0.04% | +6,740 | New |
| Public Employees Retirement Association of Colorado | 6,796 | $185.0K | 0.00% | 00.0% | Unchanged |
| Griffin Asset Management, Inc. | 7,382 | $200.9K | 0.02% | +7,382 | New |
| Teacher Retirement System of Texas | 8,167 | $222.3K | 0.00% | −5,317−39.4% | Reduced |
| Campbell & CO Investment Adviser LLC | 8,226 | $223.9K | 0.01% | +8,226 | New |
| Fiduciary Trust Co | 8,247 | $224.5K | 0.00% | +2,793+51.2% | Added |
| Inscription Capital, LLC | 8,595 | $234.0K | 0.02% | +8,595 | New |
| Diversified Trust Co | 9,162 | $249.4K | 0.00% | +9,162 | New |
| Two Sigma Securities, LLC | 9,198 | $250.4K | 0.03% | +9,198 | New |
| China Universal Asset Management Co., Ltd. | 9,502 | $258.6K | 0.02% | −682−6.7% | Reduced |
| STRS Ohio | 10,000 | $272.2K | 0.00% | +10,000 | New |
| Voya Investment Management LLC | 10,134 | $275.8K | 0.00% | 00.0% | Unchanged |
| Capstone Investment Advisors, LLC | 10,355 | $281.9K | 0.00% | +10,355 | New |
| Creative Planning | 10,370 | $282.3K | 0.00% | −2,749−21.0% | Reduced |
| Great West Life Assurance Co | 10,437 | $284.0K | 0.00% | −9,888−48.6% | Reduced |
| Gallagher Fiduciary Advisors, LLC | 11,245 | $306.1K | 0.01% | −15−0.1% | Reduced |
| KLP Kapitalforvaltning AS | 11,800 | $321.2K | 0.00% | 00.0% | Unchanged |
| Pale Fire Capital SE | 11,850 | $322.6K | 0.04% | +11,850 | New |
| Quest Partners LLC | 11,963 | $325.6K | 0.02% | +6,552+121.1% | Added |
| Nomura Holdings Inc | 12,355 | $336.3K | 0.00% | +12,355 | New |
| Fox Run Management, L.L.C. | 12,567 | $342.1K | 0.05% | +12,567 | New |
| Bridgefront Capital, LLC | 12,649 | $344.3K | 0.09% | +12,649 | New |
| Commerce Bank | 12,656 | $344.5K | 0.00% | +3,497+38.2% | Added |
| Envestnet Asset Management Inc | 12,735 | $346.6K | 0.00% | +3,312+35.1% | Added |
| ProShare Advisors LLC | 12,897 | $351.1K | 0.00% | +1,169+10.0% | Added |
| Royal Bank of Canada | 13,055 | $354.0K | 0.00% | −4,472−25.5% | Reduced |
| AlphaCentric Advisors LLC | 13,141 | $357.7K | 0.36% | +13,141 | New |
| Atria Investments LLC | 14,053 | $382.5K | 0.00% | +667+5.0% | Added |
| Toroso Investments, LLC | 14,247 | $387.8K | 0.00% | −667−4.5% | Reduced |
| SEI Investments Co | 14,352 | $390.7K | 0.00% | −17,948−55.6% | Reduced |
| Arizona State Retirement System | 15,330 | $417.3K | 0.00% | −925−5.7% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 15,640 | $425.7K | 0.00% | +70.0% | Added |