Agios Pharmaceuticals, Inc.
AGIO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001439222
In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 1 sale; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Agios Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 238
- +21 vs. Q3 2025
- Shares held
- 61.3M
- −2.05M (−3.2%) vs. Q3 2025
- Total value
- $1.67B
- −$870.9M (−34.3%) vs. Q3 2025
- New holders
- 65
- 79 more added
- Sold out
- 44
- 70 more reduced
4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 238 | $2.45B |
| Q1 2026 | 234 | $2.12B |
| Q4 2025 | 238 | $1.67B |
| Q3 2025 | 221 | $2.55B |
| Q2 2025 | 216 | $2.05B |
| Q1 2025 | 221 | $1.76B |
| Q4 2024 | 225 | $1.97B |
| Q3 2024 | 208 | $2.58B |
| Q2 2024 | 206 | $2.51B |
| Q1 2024 | 187 | $1.81B |
| Q4 2023 | 170 | $1.33B |
| Q3 2023 | 146 | $1.46B |
| Q2 2023 | 153 | $1.68B |
| Q1 2023 | 165 | $1.36B |
| Q4 2022 | 160 | $1.67B |
| Q3 2022 | 168 | $1.64B |
| Q2 2022 | 157 | $1.31B |
| Q1 2022 | 161 | $1.74B |
| Q4 2021 | 161 | $1.95B |
| Q3 2021 | 165 | $2.81B |
| Q2 2021 | 186 | $3.63B |
| Q1 2021 | 175 | $3.37B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Freestone Grove Partners LP | 40,841 | $1.11M | 0.01% | +25,417+164.8% | Added |
| Profund Advisors LLC | 39,850 | $1.08M | 0.03% | +24,741+163.8% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 39,455 | $1.07M | 0.00% | +2,863+7.8% | Added |
| Boothbay Fund Management, LLC | 37,291 | $1.02M | 0.03% | −458,050−92.5% | Reduced |
| Harbor Capital Advisors, Inc. | 37,228 | $1.01M | 0.08% | +2,393+6.9% | Added |
| Aquatic Capital Management LLC | 36,006 | $980.1K | 0.03% | +36,006 | New |
| Quadrature Capital Ltd | 35,857 | $976.0K | 0.01% | +35,857 | New |
| Capital Fund Management S.A. | 35,788 | $974.1K | 0.01% | +35,788 | New |
| Edgewood Management LLC | 35,000 | $952.7K | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 34,637 | $942.8K | 0.00% | −936−2.6% | Reduced |
| Prelude Capital Management, LLC | 33,685 | $916.9K | 0.07% | +33,685 | New |
| Hennion & Walsh Asset Management, Inc. | 33,470 | $911.1K | 0.03% | +7,969+31.2% | Added |
| Jump Financial, LLC | 33,052 | $899.7K | 0.01% | −54,848−62.4% | Reduced |
| MetLife Investment Management | 32,217 | $876.9K | 0.00% | −1,815−5.3% | Reduced |
| Seven Fleet Capital Management LP | 31,738 | $863.9K | 0.58% | +31,738 | New |
| Ishara Investments LP | 30,000 | $816.6K | 0.95% | +30,000 | New |
| Intech Investment Management LLC | 27,827 | $757.5K | 0.01% | +4,249+18.0% | Added |
| AQR Capital Management LLC | 27,926 | $754.0K | 0.00% | −63,709−69.5% | Reduced |
| Victory Capital Management Inc | 27,697 | $753.9K | 0.00% | −2,535−8.4% | Reduced |
| Quantinno Capital Management LP | 26,855 | $731.0K | 0.00% | +26,855 | New |
| Aigen Investment Management, LP | 25,915 | $705.4K | 0.16% | +25,915 | New |
| Virtus Investment Advisers, Inc. | 25,060 | $682.1K | 0.19% | +12,179+94.6% | Added |
| Federated Hermes, Inc. | 25,055 | $682.0K | 0.00% | +25,002+47,173.6% | Added |
| Russell Investments Group, Ltd. | 24,679 | $671.8K | 0.00% | +17,823+260.0% | Added |
| FMR LLC | 24,334 | $662.4K | 0.00% | +3,622+17.5% | Added |
| Janus Henderson Group PLC | 23,797 | $648.2K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 23,620 | $642.9K | 0.00% | +3,144+15.4% | Added |
| Rockefeller Capital Management L.P. | 21,071 | $573.6K | 0.00% | +5,033+31.4% | Added |
| Oak Ridge Investments LLC | 20,004 | $544.5K | 0.03% | −5,381−21.2% | Reduced |
| Brevan Howard Capital Management LP | 19,336 | $526.3K | 0.01% | +7,265+60.2% | Added |
| Handelsbanken Fonder AB | 19,323 | $526.0K | 0.00% | 00.0% | Unchanged |
| Entropy Technologies, LP | 19,163 | $521.6K | 0.03% | +19,163 | New |
| VARCOV Co. | 19,104 | $520.0K | 0.21% | +19,104 | New |
| Canada Pension Plan Investment Board | 18,200 | $495.4K | 0.00% | +18,200 | New |
| Knott David M Jr | 18,000 | $490.0K | 0.23% | +18,000 | New |
| CWM Advisors, LLC | 17,115 | $465.9K | 0.04% | +5,720+50.2% | Added |
| Winton Group Ltd | 16,751 | $456.0K | 0.02% | +351+2.1% | Added |
| State Board of Administration of Florida Retirement System | 15,847 | $431.4K | 0.00% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 15,640 | $425.7K | 0.00% | +70.0% | Added |
| Arizona State Retirement System | 15,330 | $417.3K | 0.00% | −925−5.7% | Reduced |
| SEI Investments Co | 14,352 | $390.7K | 0.00% | −17,948−55.6% | Reduced |
| Toroso Investments, LLC | 14,247 | $387.8K | 0.00% | −667−4.5% | Reduced |
| Atria Investments LLC | 14,053 | $382.5K | 0.00% | +667+5.0% | Added |
| AlphaCentric Advisors LLC | 13,141 | $357.7K | 0.36% | +13,141 | New |
| Royal Bank of Canada | 13,055 | $354.0K | 0.00% | −4,472−25.5% | Reduced |
| ProShare Advisors LLC | 12,897 | $351.1K | 0.00% | +1,169+10.0% | Added |
| Envestnet Asset Management Inc | 12,735 | $346.6K | 0.00% | +3,312+35.1% | Added |
| Commerce Bank | 12,656 | $344.5K | 0.00% | +3,497+38.2% | Added |
| Bridgefront Capital, LLC | 12,649 | $344.3K | 0.09% | +12,649 | New |
| Fox Run Management, L.L.C. | 12,567 | $342.1K | 0.05% | +12,567 | New |
| Nomura Holdings Inc | 12,355 | $336.3K | 0.00% | +12,355 | New |
| Quest Partners LLC | 11,963 | $325.6K | 0.02% | +6,552+121.1% | Added |
| Pale Fire Capital SE | 11,850 | $322.6K | 0.04% | +11,850 | New |
| KLP Kapitalforvaltning AS | 11,800 | $321.2K | 0.00% | 00.0% | Unchanged |
| Gallagher Fiduciary Advisors, LLC | 11,245 | $306.1K | 0.01% | −15−0.1% | Reduced |
| Great West Life Assurance Co | 10,437 | $284.0K | 0.00% | −9,888−48.6% | Reduced |
| Creative Planning | 10,370 | $282.3K | 0.00% | −2,749−21.0% | Reduced |
| Capstone Investment Advisors, LLC | 10,355 | $281.9K | 0.00% | +10,355 | New |
| Voya Investment Management LLC | 10,134 | $275.8K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 10,000 | $272.2K | 0.00% | +10,000 | New |
| China Universal Asset Management Co., Ltd. | 9,502 | $258.6K | 0.02% | −682−6.7% | Reduced |
| Two Sigma Securities, LLC | 9,198 | $250.4K | 0.03% | +9,198 | New |
| Diversified Trust Co | 9,162 | $249.4K | 0.00% | +9,162 | New |
| Inscription Capital, LLC | 8,595 | $234.0K | 0.02% | +8,595 | New |
| Fiduciary Trust Co | 8,247 | $224.5K | 0.00% | +2,793+51.2% | Added |
| Campbell & CO Investment Adviser LLC | 8,226 | $223.9K | 0.01% | +8,226 | New |
| Teacher Retirement System of Texas | 8,167 | $222.3K | 0.00% | −5,317−39.4% | Reduced |
| Griffin Asset Management, Inc. | 7,382 | $200.9K | 0.02% | +7,382 | New |
| Public Employees Retirement Association of Colorado | 6,796 | $185.0K | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 6,740 | $183.5K | 0.04% | +6,740 | New |
| Tower Research Capital LLC (TRC) | 6,634 | $180.6K | 0.00% | +5,277+388.9% | Added |
| Ensign Peak Advisors, Inc | 6,570 | $178.8K | 0.00% | −6,050−47.9% | Reduced |
| Simplex Trading, LLC | 6,209 | $169.0K | 0.00% | +6,209 | New |
| Contravisory Investment Management, Inc. | 6,189 | $168.5K | 0.03% | +6,189 | New |
| State of Alaska, Department of Revenue | 5,000 | $136.0K | 0.00% | +5,000 | New |
| Ameritas Investment Partners, Inc. | 4,719 | $128.5K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 4,710 | $128.2K | 0.00% | +156+3.4% | Added |
| Sterling Capital Management LLC | 3,283 | $89.4K | 0.00% | −628−16.1% | Reduced |
| First Horizon Corp | 3,095 | $84.2K | 0.00% | +1,971+175.4% | Added |
| KBC Group NV | 3,020 | $82.0K | 0.00% | +1,269+72.5% | Added |
| Quarry LP | 3,000 | $81.7K | 0.01% | −2,000−40.0% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,834 | $77.1K | 0.00% | +588+26.2% | Added |
| Eurizon Capital SGR S.p.A. | 2,647 | $72.3K | 0.00% | +2,647 | New |
| Amalgamated Bank | 1,774 | $48.0K | 0.00% | −183−9.4% | Reduced |
| Advisor Group Holdings, Inc. | 1,747 | $47.6K | 0.00% | +1,411+419.9% | Added |
| Assetmark, Inc | 1,317 | $35.8K | 0.00% | +362+37.9% | Added |
| GF Fund Management Co. Ltd. | 1,145 | $31.2K | 0.00% | −105−8.4% | Reduced |
| T. Rowe Price Investment Management, Inc. | 892 | $25.0K | 0.00% | +892 | New |
| Torren Management, LLC | 615 | $16.7K | 0.01% | +615 | New |
| US Bancorp | 509 | $13.9K | 0.00% | −60−10.5% | Reduced |
| City Holding Co | 500 | $13.6K | 0.00% | +500 | New |
| Hurley Capital, LLC | 486 | $13.2K | 0.01% | +120+32.8% | Added |
| CWM, LLC | 484 | $13.0K | 0.00% | −4,307−89.9% | Reduced |
| Los Angeles Capital Management LLC | 300 | $13.0K | 0.00% | +300 | New |
| Smartleaf Asset Management LLC | 460 | $12.6K | 0.00% | +62+15.6% | Added |
| Signaturefd, LLC | 399 | $10.9K | 0.00% | −114−22.2% | Reduced |
| Quantbot Technologies LP | 386 | $10.5K | 0.00% | −1,590−80.5% | Reduced |
| Aspect Partners, LLC | 361 | $9.83K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 295 | $8.03K | 0.00% | −485−62.2% | Reduced |
| Bell Investment Advisors, Inc | 281 | $7.65K | 0.00% | −17−5.7% | Reduced |