Karyopharm Therapeutics Inc.
KPTI- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0001503802
近 90 天，Karyopharm Therapeutics Inc. 內部人申報 0 筆公開市場買進、2 筆賣出；2026 年第 2 季末有 96 家機構在 13F 申報持有，市值合計 $2.07 億；沒有大師持有。
2022 年第 1 季 13F 持有人
Karyopharm Therapeutics Inc. 在 2022/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 139
- 較 2021 年第 4 季 −2 家
- 持有股數
- 6,829 萬
- 較 2021 年第 4 季 +1,425 萬 (+26.4%)
- 總市值
- $5.02 億
- 較 2021 年第 4 季 +$1.55 億 (+44.8%)
- 新進機構
- 26
- 另有 43 家加碼
- 清倉機構
- 28
- 另有 46 家減碼
另有 2 家機構在 2021 年第 4 季持有、還沒有申報 2022 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 KPTI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 96 | $2.07 億 |
| 2026 年第 1 季 | 77 | $9,840 萬 |
| 2025 年第 4 季 | 68 | $6,960 萬 |
| 2025 年第 3 季 | 52 | $1,946 萬 |
| 2025 年第 2 季 | 50 | $1,902 萬 |
| 2025 年第 1 季 | 50 | $1,374 萬 |
| 2024 年第 4 季 | 87 | $4,120 萬 |
| 2024 年第 3 季 | 91 | $4,922 萬 |
| 2024 年第 2 季 | 114 | $5,863 萬 |
| 2024 年第 1 季 | 114 | $1.13 億 |
| 2023 年第 4 季 | 120 | $6,348 萬 |
| 2023 年第 3 季 | 120 | $1.03 億 |
| 2023 年第 2 季 | 138 | $1.45 億 |
| 2023 年第 1 季 | 132 | $3.40 億 |
| 2022 年第 4 季 | 155 | $3.34 億 |
| 2022 年第 3 季 | 147 | $3.64 億 |
| 2022 年第 2 季 | 150 | $3.03 億 |
| 2022 年第 1 季 | 139 | $5.02 億 |
| 2021 年第 4 季 | 143 | $3.47 億 |
| 2021 年第 3 季 | 134 | $3.34 億 |
| 2021 年第 2 季 | 154 | $6.09 億 |
| 2021 年第 1 季 | 171 | $6.37 億 |
2022 年第 1 季持有機構
每家機構持有 Karyopharm Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2021 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Parametric Portfolio Associates LLC | 256,291 | $188.9 萬 | 0.00% | −21,228−7.6% | 減碼 |
| Birchview Capital, LP | 269,332 | $198.5 萬 | 1.43% | +23,332+9.5% | 加碼 |
| Susquehanna International Group, LLP | 281,129 | $207.2 萬 | 0.00% | −321,697−53.4% | 減碼 |
| Bank of New York Mellon Corp | 296,900 | $218.8 萬 | 0.00% | −641−0.2% | 減碼 |
| Balyasny Asset Management LLC | 342,484 | $252.4 萬 | 0.01% | +342,484 | 新進 |
| Macquarie Group Ltd | 382,041 | $281.6 萬 | 0.00% | 00.0% | 不變 |
| Hennion & Walsh Asset Management, Inc. | 385,837 | $284.4 萬 | 0.15% | −7,855−2.0% | 減碼 |
| Jane Street Group, LLC | 416,843 | $307.2 萬 | 0.01% | +209,700+101.2% | 加碼 |
| Acadian Asset Management LLC | 498,922 | $367.4 萬 | 0.02% | +498,922 | 新進 |
| UBS Group AG | 518,460 | $382.0 萬 | 0.00% | +251,465+94.2% | 加碼 |
| Deutsche Bank AG | 599,436 | $441.8 萬 | 0.00% | +551,470+1,149.7% | 加碼 |
| Altium Capital Management LP | 645,000 | $475.4 萬 | 1.66% | +645,000 | 新進 |
| Jacobs Levy Equity Management, Inc | 663,512 | $489.0 萬 | 0.03% | +663,512 | 新進 |
| Voloridge Investment Management, LLC | 676,834 | $498.8 萬 | 0.03% | +479,443+242.9% | 加碼 |
| JPMorgan Chase & Co | 718,640 | $529.7 萬 | 0.00% | −24,760−3.3% | 減碼 |
| Northern Trust Corp | 764,335 | $563.3 萬 | 0.00% | −11,216−1.4% | 減碼 |
| Two Sigma Advisers, LP | 775,300 | $571.4 萬 | 0.02% | +347,700+81.3% | 加碼 |
| Lombard Odier Asset Management (Switzerland) SA | 776,053 | $572.0 萬 | 0.45% | −881,994−53.2% | 減碼 |
| Rafferty Asset Management, LLC | 808,939 | $596.2 萬 | 0.04% | +428,371+112.6% | 加碼 |
| Citadel Advisors LLC | 854,517 | $629.8 萬 | 0.01% | +625,634+273.3% | 加碼 |
| Goldman Sachs Group Inc | 898,906 | $662.5 萬 | 0.00% | −129,976−12.6% | 減碼 |
| Bank of America Corp | 1,116,230 | $822.7 萬 | 0.00% | +861,362+338.0% | 加碼 |
| Two Sigma Investments, LP | 1,117,925 | $823.9 萬 | 0.02% | +128,894+13.0% | 加碼 |
| Millennium Management LLC | 1,252,873 | $923.4 萬 | 0.01% | −267,351−17.6% | 減碼 |
| Frontier Capital Management Co LLC | 1,279,295 | $942.8 萬 | 0.09% | −406,110−24.1% | 減碼 |
| Candriam Luxembourg S.C.A. | 1,335,026 | $983.9 萬 | 0.07% | +457,358+52.1% | 加碼 |
| Geode Capital Management, LLC | 1,337,888 | $986.0 萬 | 0.00% | −104,843−7.3% | 減碼 |
| Rice Hall James & Associates, LLC | 1,344,929 | $991.2 萬 | 0.39% | +68,295+5.3% | 加碼 |
| C WorldWide Group Holding A/S | 1,500,000 | $1,106 萬 | 0.12% | 00.0% | 不變 |
| Nuveen Asset Management, LLC | 1,819,048 | $1,192 萬 | 0.00% | +634,738+53.6% | 加碼 |
| Iron Triangle Partners LP | 2,000,000 | $1,474 萬 | 1.75% | +2,000,000 | 新進 |
| Morgan Stanley | 2,812,563 | $2,073 萬 | 0.00% | +1,746,944+163.9% | 加碼 |
| Commodore Capital LP | 3,561,052 | $2,625 萬 | 5.86% | +3,561,052 | 新進 |
| Rubric Capital Management LP | 3,607,443 | $2,659 萬 | 1.24% | +825,000+29.7% | 加碼 |
| Vanguard Group Inc | 3,960,708 | $2,919 萬 | 0.00% | +601,901+17.9% | 加碼 |
| Palo Alto Investors LP | 5,621,533 | $4,143 萬 | 3.20% | +151,081+2.8% | 加碼 |
| BlackRock Inc. | 7,927,618 | $5,843 萬 | 0.00% | −990,588−11.1% | 減碼 |
| State Street Corp | 10,966,701 | $8,083 萬 | 0.00% | +5,453,021+98.9% | 加碼 |
| Aaron Wealth Advisors | 2,837 | – | – | +2,837 | 新進 |
| Alkeon Capital Management LLC | 0 | $0 | 0.00% | −1,961,588−100.0% | 清倉 |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −274,243−100.0% | 清倉 |
| Jennison Associates LLC | 0 | $0 | 0.00% | −270,757−100.0% | 清倉 |
| HRT Financial LP | 0 | $0 | 0.00% | −248,332−100.0% | 清倉 |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −208,526−100.0% | 清倉 |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −191,976−100.0% | 清倉 |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −124,274−100.0% | 清倉 |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −120,114−100.0% | 清倉 |
| Jump Financial, LLC | 0 | $0 | 0.00% | −85,615−100.0% | 清倉 |
| Algert Global LLC | 0 | $0 | 0.00% | −78,239−100.0% | 清倉 |
| Dynamic Technology Lab Private Ltd | 0 | $0 | 0.00% | −61,045−100.0% | 清倉 |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −58,733−100.0% | 清倉 |
| Virginia Retirement Systems Et Al | 0 | $0 | 0.00% | −43,100−100.0% | 清倉 |
| Patriot Financial Group Insurance Agency, LLC | 0 | $0 | 0.00% | −38,750−100.0% | 清倉 |
| Spearhead Capital Advisors, LLC | 0 | $0 | 0.00% | −34,459−100.0% | 清倉 |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −28,200−100.0% | 清倉 |
| Bridgefront Capital, LLC | 0 | $0 | 0.00% | −24,396−100.0% | 清倉 |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −23,716−100.0% | 清倉 |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −21,000−100.0% | 清倉 |
| North Star Investment Management Corp. | 0 | $0 | 0.00% | −20,000−100.0% | 清倉 |
| Assenagon Asset Management S.A. | 0 | $0 | 0.00% | −19,366−100.0% | 清倉 |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −15,443−100.0% | 清倉 |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −12,618−100.0% | 清倉 |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −9,006−100.0% | 清倉 |
| Belvedere Trading LLC | 0 | $0 | 0.00% | −5,371−100.0% | 清倉 |
| Parallel Advisors, LLC | 0 | $0 | 0.00% | −324−100.0% | 清倉 |
| Glassman Wealth Services | 0 | $0 | 0.00% | −45−100.0% | 清倉 |
| Dark Forest Capital Management LP | 0 | $0 | 0.00% | −22−100.0% | 清倉 |
| AlphaCentric Advisors LLC | – | – | – | – | 本季未申報 |
| Harbour Investments, Inc. | – | – | – | – | 本季未申報 |