Xeris Biopharma Holdings, Inc.
XERS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001867096
In the last 90 days, Xeris Biopharma Holdings, Inc. insiders filed 0 open-market purchases and 8 sales; 242 institutions reported holding it in 13F filings for Q2 2026, worth $857.1M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Xeris Biopharma Holdings, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 231
- +32 vs. Q2 2025
- Shares held
- 97.0M
- +6.99M (+7.8%) vs. Q2 2025
- Total value
- $789.3M
- +$369.1M (+87.8%) vs. Q2 2025
- New holders
- 59
- 77 more added
- Sold out
- 27
- 61 more reduced
2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XERS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 242 | $857.1M |
| Q1 2026 | 239 | $610.3M |
| Q4 2025 | 227 | $792.0M |
| Q3 2025 | 231 | $789.3M |
| Q2 2025 | 201 | $422.9M |
| Q1 2025 | 199 | $480.9M |
| Q4 2024 | 162 | $222.2M |
| Q3 2024 | 144 | $182.2M |
| Q2 2024 | 135 | $136.6M |
| Q1 2024 | 142 | $133.7M |
| Q4 2023 | 120 | $140.8M |
| Q3 2023 | 111 | $102.3M |
| Q2 2023 | 105 | $146.7M |
| Q1 2023 | 92 | $80.6M |
| Q4 2022 | 97 | $71.6M |
| Q3 2022 | 101 | $89.3M |
| Q2 2022 | 103 | $91.3M |
| Q1 2022 | 103 | $129.2M |
| Q4 2021 | 92 | $120.2M |
| Q3 2021 | 71 | $42.9M |
| Q2 2021 | 94 | $114.9M |
| Q1 2021 | 103 | $149.7M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Xeris Biopharma Holdings, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| LPL Financial LLC | 33,302 | $271.1K | 0.00% | −9,750−22.6% | Reduced |
| KLP Kapitalforvaltning AS | 33,400 | $271.9K | 0.00% | +33,400 | New |
| Cambridge Investment Research Advisors, Inc. | 34,642 | $282.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 36,285 | $295.0K | 0.00% | −8,068−18.2% | Reduced |
| State Board of Administration of Florida Retirement System | 37,970 | $309.1K | 0.00% | 00.0% | Unchanged |
| Tudor Investment Corp Et Al | 37,994 | $309.3K | 0.00% | −187,192−83.1% | Reduced |
| Teacher Retirement System of Texas | 39,321 | $320.1K | 0.00% | +39,321 | New |
| Advisor Group Holdings, Inc. | 40,351 | $324.8K | 0.00% | −2,358−5.5% | Reduced |
| Cetera Investment Advisers | 40,018 | $325.7K | 0.00% | −6,314−13.6% | Reduced |
| Savvy Advisors, Inc. | 40,465 | $329.4K | 0.02% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 41,362 | $336.7K | 0.00% | +9,703+30.6% | Added |
| LJI Wealth Management, LLC | 42,350 | $344.7K | 0.06% | 00.0% | Unchanged |
| Gotham Asset Management, LLC | 42,741 | $347.9K | 0.00% | +9,975+30.4% | Added |
| New York State Common Retirement Fund | 43,422 | $353.5K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 45,931 | $373.0K | 0.01% | −30,713−40.1% | Reduced |
| Arizona State Retirement System | 47,362 | $385.5K | 0.00% | +47,362 | New |
| Occudo Quantitative Strategies LP | 47,674 | $388.1K | 0.05% | −131,680−73.4% | Reduced |
| Weiss Asset Management LP | 50,001 | $407.0K | 0.01% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 50,144 | $408.2K | 0.00% | −4,328−7.9% | Reduced |
| EntryPoint Capital, LLC | 53,015 | $431.5K | 0.17% | −19,884−27.3% | Reduced |
| Intech Investment Management LLC | 55,336 | $450.4K | 0.00% | −39,101−41.4% | Reduced |
| CWM, LLC | 55,439 | $451.0K | 0.00% | +328+0.6% | Added |
| Palumbo Wealth Management LLC | 63,189 | $514.4K | 0.16% | +63,189 | New |
| GPS Wealth Strategies Group, LLC | 65,089 | $529.8K | 0.06% | +164+0.3% | Added |
| STRS Ohio | 65,500 | $533.2K | 0.00% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 68,716 | $559.0K | 0.05% | +6,394+10.3% | Added |
| Quantbot Technologies LP | 69,365 | $564.6K | 0.02% | +26,420+61.5% | Added |
| Janus Henderson Group PLC | 69,887 | $569.2K | 0.00% | +69,887 | New |
| Citigroup Inc | 70,255 | $571.9K | 0.00% | −7,279−9.4% | Reduced |
| Bayesian Capital Management, LP | 70,800 | $576.3K | 0.12% | +70,800 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 71,331 | $580.6K | 0.00% | −10,807−13.2% | Reduced |
| Round Rock Advisors, LLC | 63,772 | $582.2K | 0.09% | +63,772 | New |
| HRT Financial LP | 72,543 | $590.0K | 0.00% | +72,543 | New |
| Diadema Partners LP | 74,753 | $608.5K | 0.42% | +74,753 | New |
| OrbiMed Advisors LLC | 80,420 | $654.6K | 0.02% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 81,471 | $663.2K | 0.00% | −324,731−79.9% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 82,181 | $669.0K | 0.02% | −254,033−75.6% | Reduced |
| Quarry LP | 82,500 | $671.5K | 0.16% | −80,000−49.2% | Reduced |
| Aquatic Capital Management LLC | 83,000 | $675.6K | 0.01% | +83,000 | New |
| SG Americas Securities, LLC | 83,214 | $677.0K | 0.00% | +63,921+331.3% | Added |
| ExodusPoint Capital Management, LP | 86,920 | $707.5K | 0.01% | +86,920 | New |
| MetLife Investment Management | 87,318 | $710.8K | 0.00% | 00.0% | Unchanged |
| Winton Group Ltd | 90,793 | $739.1K | 0.03% | +90,793 | New |
| Wells Fargo & Company | 97,196 | $791.2K | 0.00% | +16,830+20.9% | Added |
| Thompson Siegel & Walmsley LLC | 100,884 | $821.0K | 0.01% | −165,503−62.1% | Reduced |
| Campbell & CO Investment Adviser LLC | 103,616 | $843.4K | 0.06% | −28,766−21.7% | Reduced |
| Principal Financial Group Inc | 105,493 | $858.7K | 0.00% | −48,444−31.5% | Reduced |
| Ieq Capital, LLC | 107,953 | $878.7K | 0.00% | −542−0.5% | Reduced |
| Fred Alger Management, LLC | 108,936 | $886.7K | 0.00% | +108,936 | New |
| Franklin Resources Inc | 109,142 | $888.4K | 0.00% | +5,864+5.7% | Added |
| Engineers Gate Manager LP | 109,994 | $895.4K | 0.01% | +71,954+189.2% | Added |
| Roundview Capital LLC | 120,000 | $976.8K | 0.06% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 120,900 | $984.1K | 0.02% | +98,326+435.6% | Added |
| SEI Investments Co | 121,176 | $986.4K | 0.00% | +4,642+4.0% | Added |
| Globeflex Capital L P | 123,184 | $1.00M | 0.15% | +42,753+53.2% | Added |
| Creative Planning | 126,980 | $1.03M | 0.00% | +9,225+7.8% | Added |
| CWM Advisors, LLC | 128,494 | $1.05M | 0.10% | +128,494 | New |
| Brevan Howard Capital Management LP | 132,160 | $1.08M | 0.02% | −72,864−35.5% | Reduced |
| Polen Capital Management LLC | 133,191 | $1.08M | 0.00% | +197+0.1% | Added |
| Dark Forest Capital Management LP | 136,731 | $1.11M | 0.04% | +136,731 | New |
| Calamos Advisors LLC | 137,097 | $1.12M | 0.00% | +137,097 | New |
| Alliancebernstein L.P. | 144,830 | $1.18M | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 151,886 | $1.24M | 0.00% | +141,725+1,394.8% | Added |
| Mackenzie Financial Corp | 152,161 | $1.24M | 0.00% | +14,069+10.2% | Added |
| Ameriprise Financial Inc | 154,168 | $1.25M | 0.00% | +5,140+3.4% | Added |
| Algert Global LLC | 157,960 | $1.29M | 0.02% | +157,960 | New |
| Price T Rowe Associates Inc | 166,788 | $1.36M | 0.00% | +13,517+8.8% | Added |
| UBS Asset Management Americas Inc | 183,459 | $1.49M | 0.00% | +145,840+387.7% | Added |
| Commonwealth Equity Services, LLC | 197,743 | $1.61M | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 205,213 | $1.67M | 0.00% | −3,933−1.9% | Reduced |
| Rhumbline Advisers | 213,744 | $1.74M | 0.00% | −1,947−0.9% | Reduced |
| Legato Capital Management LLC | 216,805 | $1.76M | 0.19% | 00.0% | Unchanged |
| Trexquant Investment LP | 229,420 | $1.87M | 0.02% | +229,420 | New |
| Russell Investments Group, Ltd. | 251,378 | $2.05M | 0.00% | +128,189+104.1% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 254,000 | $2.07M | 0.00% | +2,000+0.8% | Added |
| IHT Wealth Management, LLC | 258,175 | $2.10M | 0.05% | −5,630−2.1% | Reduced |
| Caxton Associates LLP | 281,337 | $2.29M | 0.06% | +281,337 | New |
| Schonfeld Strategic Advisors LLC | 304,504 | $2.48M | 0.02% | −84,562−21.7% | Reduced |
| Swiss National Bank | 310,400 | $2.53M | 0.00% | +310,400 | New |
| Harvest Investment Services, LLC | 325,555 | $2.65M | 0.53% | +213,585+190.8% | Added |
| Barclays PLC | 346,639 | $2.82M | 0.00% | −77,609−18.3% | Reduced |
| Granahan Investment Management Inc | 350,168 | $2.85M | 0.12% | +350,168 | New |
| State of Wisconsin Investment Board | 350,529 | $2.85M | 0.01% | +72,509+26.1% | Added |
| FMR LLC | 360,178 | $2.93M | 0.00% | +33,758+10.3% | Added |
| Canada Pension Plan Investment Board | 375,700 | $3.06M | 0.00% | +375,700 | New |
| Voya Investment Management LLC | 400,079 | $3.26M | 0.00% | +358,689+866.6% | Added |
| Divisadero Street Capital Management, LP | 406,334 | $3.31M | 0.15% | +406,334 | New |
| Citadel Advisors LLC | 437,612 | $3.56M | 0.00% | +437,612 | New |
| Bank of New York Mellon Corp | 439,838 | $3.58M | 0.00% | +62,711+16.6% | Added |
| Redmile Group, LLC | 451,099 | $3.67M | 0.36% | 00.0% | Unchanged |
| Millennium Management LLC | 524,749 | $4.27M | 0.00% | −2,408,871−82.1% | Reduced |
| Wellington Management Group LLP | 580,962 | $4.73M | 0.00% | +181,671+45.5% | Added |
| BNP Paribas Arbitrage, SA | 581,719 | $4.74M | 0.00% | +565,409+3,466.6% | Added |
| Invesco Ltd. | 583,108 | $4.75M | 0.00% | +496,914+576.5% | Added |
| EAM Investors, LLC | 603,101 | $4.85M | 0.56% | +16,236+2.8% | Added |
| Jump Financial, LLC | 603,244 | $4.91M | 0.06% | −153,159−20.2% | Reduced |
| Walleye Capital LLC | 623,962 | $5.08M | 0.04% | +380,687+156.5% | Added |
| Squarepoint Ops LLC | 679,081 | $5.53M | 0.01% | +394,514+138.6% | Added |
| CenterBook Partners LP | 698,204 | $5.68M | 0.28% | −896,025−56.2% | Reduced |
| Federated Hermes, Inc. | 704,383 | $5.73M | 0.01% | +13,002+1.9% | Added |