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Wave Life Sciences, Inc.

WVE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001631574

In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q1 2026

Institutional positions in Wave Life Sciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
232
+16 vs. Q4 2025
Shares held
172.6M
−6.53M (−3.6%) vs. Q4 2025
Total value
$1.25B
−$1.80B (−59.0%) vs. Q4 2025
New holders
51
107 more added
Sold out
35
48 more reduced

3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 232 institutions
Q1 2021: 102 institutionsQ2 2021: 87 institutionsQ3 2021: 88 institutionsQ4 2021: 90 institutionsQ1 2022: 82 institutionsQ2 2022: 60 institutionsQ3 2022: 61 institutionsQ4 2022: 75 institutionsQ1 2023: 73 institutionsQ2 2023: 81 institutionsQ3 2023: 85 institutionsQ4 2023: 115 institutionsQ1 2024: 132 institutionsQ2 2024: 144 institutionsQ3 2024: 162 institutionsQ4 2024: 184 institutionsQ1 2025: 197 institutionsQ2 2025: 177 institutionsQ3 2025: 189 institutionsQ4 2025: 219 institutionsQ1 2026: 232 institutionsQ2 2026: 239 institutions
Value heldQ1 2026: $1.25B
Q1 2021: $214.8MQ2 2021: $246.7MQ3 2021: $183.5MQ4 2021: $148.5MQ1 2022: $95.4MQ2 2022: $220.3MQ3 2022: $242.8MQ4 2022: $476.9MQ1 2023: $303.5MQ2 2023: $262.7MQ3 2023: $417.4MQ4 2023: $468.0MQ1 2024: $572.3MQ2 2024: $474.4MQ3 2024: $986.1MQ4 2024: $1.59BQ1 2025: $1.06BQ2 2025: $903.1MQ3 2025: $1.05BQ4 2025: $3.11BQ1 2026: $1.25BQ2 2026: $1.06B
Institutions holding WVE and their total value by quarter
QuarterHoldersValue
Q2 2026239$1.06B
Q1 2026232$1.25B
Q4 2025219$3.11B
Q3 2025189$1.05B
Q2 2025177$903.1M
Q1 2025197$1.06B
Q4 2024184$1.59B
Q3 2024162$986.1M
Q2 2024144$474.4M
Q1 2024132$572.3M
Q4 2023115$468.0M
Q3 202385$417.4M
Q2 202381$262.7M
Q1 202373$303.5M
Q4 202275$476.9M
Q3 202261$242.8M
Q2 202260$220.3M
Q1 202282$95.4M
Q4 202190$148.5M
Q3 202188$183.5M
Q2 202187$246.7M
Q1 2021102$214.8M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q4 2025.

Institutions holding WVE in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Pictet Asset Management Holding SA1,149,127$8.20M0.01%+343,226+42.6%Added
Vanguard Portfolio Management LLC1,176,207$8.53M0.00%+1,176,207New
Charles Schwab Investment Management Inc1,179,279$8.55M0.00%−12,082−1.0%Reduced
Northern Trust Corp1,189,230$8.62M0.00%+156,162+15.1%Added
Emerald Advisers, LLC1,261,183$9.14M0.29%−1,193,906−48.6%Reduced
Algert Global LLC1,315,589$9.54M0.14%+1,193,119+974.2%Added
Schroder Investment Management Group1,441,059$9.54M0.01%+435,075+43.2%Added
RTW Investments, LP1,350,000$9.79M0.10%00.0%Unchanged
Morgan Stanley1,361,001$9.87M0.00%+951,338+232.2%Added
Goldman Sachs Group Inc1,383,590$10.0M0.00%−1,470,492−51.5%Reduced
Affinity Asset Advisors, LLC1,401,727$10.2M0.60%−1,298,273−48.1%Reduced
Squarepoint Ops LLC1,462,390$10.6M0.02%+578,804+65.5%Added
Vanguard Capital Management LLC1,611,853$11.7M0.00%+1,611,853New
Pfizer Inc1,875,000$11.9M5.00%00.0%Unchanged
Marshall Wace, LLP1,789,882$13.0M0.01%+1,789,882New
First Light Asset Management, LLC1,843,968$13.4M1.20%−9,883−0.5%Reduced
Two Sigma Investments, LP1,878,115$13.6M0.01%+1,128,667+150.6%Added
Citadel Advisors LLC2,202,856$16.0M0.01%+1,412,892+178.9%Added
Siren, L.L.C.2,450,000$17.8M0.49%00.0%Unchanged
Geode Capital Management, LLC3,579,099$26.0M0.00%+408,989+12.9%Added
State Street Corp3,674,033$26.6M0.00%+677,949+22.6%Added
M28 Capital Management LP4,588,284$33.3M61.83%−1,076,264−19.0%Reduced
Primecap Management Co4,832,952$35.0M0.03%+737,670+18.0%Added
683 Capital Management, LLC4,900,000$35.5M3.30%+885,000+22.0%Added
FMR LLC5,192,761$37.6M0.00%−9,943,222−65.7%Reduced
Federated Hermes, Inc.5,317,457$38.6M0.06%+572,937+12.1%Added
Driehaus Capital Management LLC5,431,021$39.4M0.29%−1,150,046−17.5%Reduced
Price T Rowe Associates Inc8,704,550$63.1M0.01%+1,297,178+17.5%Added
Maverick Capital LtdSuperinvestorMaverick Capital10,161,399$73.7M0.86%+881,162+9.5%Added
BlackRock, Inc.14,117,412$102.4M0.00%+1,468,505+11.6%Added
GSK plc18,245,691$132.3M22.08%00.0%Unchanged
Ra Capital Management, L.P.26,975,505$195.6M2.07%+8,772,496+48.2%Added
Darwin Global Management, Ltd.0$00.00%−7,298,421−100.0%Sold out
Loomis Sayles & Co L P0$00.00%−2,040,223−100.0%Sold out
Eventide Asset Management, LLC0$00.00%−500,000−100.0%Sold out
Exome Asset Management LLC0$00.00%−421,488−100.0%Sold out
Boone Capital Management LLC0$00.00%−352,144−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−338,546−100.0%Sold out
Jain Global LLC0$00.00%−328,145−100.0%Sold out
EAM Investors, LLC0$00.00%−248,815−100.0%Sold out
Squadron Capital Management LLC0$00.00%−175,000−100.0%Sold out
Principal Financial Group Inc0$00.00%−170,170−100.0%Sold out
Jane Street Group, LLC0$00.00%−110,924−100.0%Sold out
Itau Unibanco Holding S.A.0$00.00%−102,000−100.0%Sold out
LMR Partners LLP0$00.00%−100,000−100.0%Sold out
Seven Grand Managers, LLC0$00.00%−100,000−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−95,068−100.0%Sold out
Prelude Capital Management, LLC0$00.00%−93,202−100.0%Sold out
Prescott Group Capital Management, L.L.C.0$00.00%−90,000−100.0%Sold out
Cinctive Capital Management LP0$00.00%−61,831−100.0%Sold out
Sig Brokerage, LP0$00.00%−48,384−100.0%Sold out
Gainplan LLC0$00.00%−39,972−100.0%Sold out
PSP Research LLC0$00.00%−31,040−100.0%Sold out
Vestmark Advisory Solutions, Inc.0$00.00%−30,421−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−22,000−100.0%Sold out
Persistent Asset Partners Ltd0$00.00%−19,827−100.0%Sold out
FORA Capital, LLC0$00.00%−19,194−100.0%Sold out
HSBC Holdings PLC0$00.00%−16,990−100.0%Sold out
Palumbo Wealth Management LLC0$00.00%−11,356−100.0%Sold out
Public Employees Retirement System of Ohio0$00.00%−10,700−100.0%Sold out
Amalgamated Bank0$00.00%−3,637−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−503−100.0%Sold out
Cygnus Capital Advisors, LLC0$00.00%−271−100.0%Sold out
J.Safra Asset Management Corp0$00.00%−262−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−248−100.0%Sold out
CVA Family Office, LLC0$00.00%−128−100.0%Sold out
Hughes Financial Services, LLC0$00.00%−1−100.0%Sold out
Vanguard Group Inc––––Not filed
Global Retirement Partners, LLC––––Not filed
ORG Partners LLC––––Not filed