Wave Life Sciences, Inc.
WVE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001631574
In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in Wave Life Sciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 219
- +35 vs. Q3 2025
- Shares held
- 182.7M
- +39.1M (+27.3%) vs. Q3 2025
- Total value
- $3.11B
- +$2.06B (+195.7%) vs. Q3 2025
- New holders
- 73
- 79 more added
- Sold out
- 38
- 47 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 239 | $1.06B |
| Q1 2026 | 232 | $1.25B |
| Q4 2025 | 219 | $3.11B |
| Q3 2025 | 189 | $1.05B |
| Q2 2025 | 177 | $903.1M |
| Q1 2025 | 197 | $1.06B |
| Q4 2024 | 184 | $1.59B |
| Q3 2024 | 162 | $986.1M |
| Q2 2024 | 144 | $474.4M |
| Q1 2024 | 132 | $572.3M |
| Q4 2023 | 115 | $468.0M |
| Q3 2023 | 85 | $417.4M |
| Q2 2023 | 81 | $262.7M |
| Q1 2023 | 73 | $303.5M |
| Q4 2022 | 75 | $476.9M |
| Q3 2022 | 61 | $242.8M |
| Q2 2022 | 60 | $220.3M |
| Q1 2022 | 82 | $95.4M |
| Q4 2021 | 90 | $148.5M |
| Q3 2021 | 88 | $183.5M |
| Q2 2021 | 87 | $246.7M |
| Q1 2021 | 102 | $214.8M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Emerald Advisers, LLC | 2,455,089 | $41.7M | 1.29% | −541,811−18.1% | Reduced |
| Affinity Asset Advisors, LLC | 2,700,000 | $45.9M | 3.30% | +600,000+28.6% | Added |
| Goldman Sachs Group Inc | 2,854,082 | $48.5M | 0.01% | +728,945+34.3% | Added |
| State Street Corp | 2,996,084 | $50.9M | 0.00% | +149,718+5.3% | Added |
| Geode Capital Management, LLC | 3,170,110 | $53.9M | 0.00% | +251,740+8.6% | Added |
| Vanguard Group Inc | 3,573,746 | $60.8M | 0.00% | +433,910+13.8% | Added |
| 683 Capital Management, LLC | 4,015,000 | $68.3M | 5.68% | −135,000−3.3% | Reduced |
| Primecap Management Co | 4,095,282 | $69.6M | 0.05% | +2,196,632+115.7% | Added |
| Federated Hermes, Inc. | 4,744,520 | $80.7M | 0.13% | +993,827+26.5% | Added |
| M28 Capital Management LP | 5,664,548 | $96.3M | 70.00% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 6,581,067 | $111.9M | 0.76% | +283,007+4.5% | Added |
| Darwin Global Management, Ltd. | 7,298,421 | $125.2M | 2.53% | +7,298,421 | New |
| Price T Rowe Associates Inc | 7,407,372 | $125.9M | 0.01% | +3,362,880+83.1% | Added |
| Maverick Capital LtdSuperinvestorMaverick Capital | 9,280,237 | $157.8M | 1.69% | +888,381+10.6% | Added |
| Adage Capital Partners GP, L.L.C. | 9,786,061 | $166.4M | 0.25% | −4,781,723−32.8% | Reduced |
| BlackRock, Inc. | 12,648,907 | $215.0M | 0.00% | +2,218,094+21.3% | Added |
| FMR LLC | 15,135,983 | $257.3M | 0.01% | +10,005,609+195.0% | Added |
| Ra Capital Management, L.P. | 18,203,009 | $309.5M | 3.17% | +1,0000.0% | Added |
| GSK plc | 18,245,691 | $310.2M | 38.82% | +18,245,691 | New |
| StemPoint Capital LP | 0 | $0 | 0.00% | −2,110,152−100.0% | Sold out |
| MPM Oncology Impact Management LP | 0 | $0 | 0.00% | −1,505,262−100.0% | Sold out |
| Artisan Partners Limited Partnership | 0 | $0 | 0.00% | −1,232,926−100.0% | Sold out |
| Polar Capital Holdings Plc | 0 | $0 | 0.00% | −1,062,276−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −663,967−100.0% | Sold out |
| Ensign Peak Advisors, Inc | 0 | $0 | 0.00% | −313,307−100.0% | Sold out |
| Avidity Partners Management LP | 0 | $0 | 0.00% | −297,500−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −251,700−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −127,983−100.0% | Sold out |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −119,067−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −94,080−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −81,955−100.0% | Sold out |
| Twinbeech Capital LP | 0 | $0 | 0.00% | −65,091−100.0% | Sold out |
| Franklin Resources Inc | 0 | $0 | 0.00% | −62,259−100.0% | Sold out |
| HighVista Strategies LLC | 0 | $0 | 0.00% | −59,261−100.0% | Sold out |
| SummitTX Capital, L.P. | 0 | $0 | 0.00% | −53,611−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −51,198−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −43,946−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −41,988−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −40,000−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −27,489−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −18,427−100.0% | Sold out |
| Martingale Asset Management L P | 0 | $0 | 0.00% | −16,252−100.0% | Sold out |
| Velan Capital Investment Management LP | 0 | $0 | 0.00% | −15,000−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −14,000−100.0% | Sold out |
| Kraematon Investment Advisors, Inc | 0 | $0 | 0.00% | −13,450−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −12,375−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −12,000−100.0% | Sold out |
| Verdence Capital Advisors LLC | 0 | $0 | 0.00% | −11,307−100.0% | Sold out |
| NJ State Employees Deferred Compensation Plan | 0 | $0 | 0.00% | −11,700−100.0% | Sold out |
| Chicago Partners Investment Group LLC | 0 | $0 | 0.00% | −10,572−100.0% | Sold out |
| Capstone Investment Advisors, LLC | 0 | $0 | 0.00% | −10,406−100.0% | Sold out |
| Federation des caisses Desjardins du Quebec | 0 | $0 | 0.00% | −2,350−100.0% | Sold out |
| Wealthspire Advisors, LLC | 0 | $0 | 0.00% | −1,350−100.0% | Sold out |
| Versant Capital Management, Inc | 0 | $0 | 0.00% | −108−100.0% | Sold out |
| Montag A & Associates Inc | 0 | $0 | 0.00% | −59−100.0% | Sold out |
| Principal Securities, Inc. | 0 | $0 | 0.00% | −58−100.0% | Sold out |
| American National Bank | 0 | $0 | 0.00% | −50−100.0% | Sold out |
| Glenmede Investment Management, LP | – | – | – | – | Not filed |
| CIBC Bancorp USA Inc. | – | – | – | – | Not filed |
| Wolverine Trading, LLC | – | – | – | – | Not filed |
| Point72 Hong Kong Ltd | – | – | – | – | Not filed |
| Point72 (DIFC) Ltd | – | – | – | – | Not filed |