Wave Life Sciences, Inc.
WVE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001631574
In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q3 2025
Institutional positions in Wave Life Sciences, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 189
- +14 vs. Q2 2025
- Shares held
- 143.7M
- +4.85M (+3.5%) vs. Q2 2025
- Total value
- $1.05B
- +$149.2M (+16.5%) vs. Q2 2025
- New holders
- 32
- 61 more added
- Sold out
- 18
- 62 more reduced
2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 239 | $1.06B |
| Q1 2026 | 232 | $1.25B |
| Q4 2025 | 219 | $3.11B |
| Q3 2025 | 189 | $1.05B |
| Q2 2025 | 177 | $903.1M |
| Q1 2025 | 197 | $1.06B |
| Q4 2024 | 184 | $1.59B |
| Q3 2024 | 162 | $986.1M |
| Q2 2024 | 144 | $474.4M |
| Q1 2024 | 132 | $572.3M |
| Q4 2023 | 115 | $468.0M |
| Q3 2023 | 85 | $417.4M |
| Q2 2023 | 81 | $262.7M |
| Q1 2023 | 73 | $303.5M |
| Q4 2022 | 75 | $476.9M |
| Q3 2022 | 61 | $242.8M |
| Q2 2022 | 60 | $220.3M |
| Q1 2022 | 82 | $95.4M |
| Q4 2021 | 90 | $148.5M |
| Q3 2021 | 88 | $183.5M |
| Q2 2021 | 87 | $246.7M |
| Q1 2021 | 102 | $214.8M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Twinbeech Capital LP | 65,091 | $476.5K | 0.02% | −98,654−60.2% | Reduced |
| SEI Investments Co | 72,255 | $528.9K | 0.00% | −16,564−18.6% | Reduced |
| Wells Fargo & Company | 73,811 | $540.3K | 0.00% | −50,856−40.8% | Reduced |
| a16z Perennial Management, L.P. | 77,619 | $568.2K | 0.05% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 77,895 | $570.2K | 0.05% | −15,475−16.6% | Reduced |
| Macquarie Group Ltd | 81,955 | $600.0K | 0.00% | −184,901−69.3% | Reduced |
| Knott David M Jr | 90,000 | $658.8K | 0.28% | +50,000+125.0% | Added |
| Alliancebernstein L.P. | 92,830 | $679.5K | 0.00% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 94,080 | $688.7K | 0.01% | +83,816+816.6% | Added |
| Deutsche Bank AG | 94,265 | $690.0K | 0.00% | +9,734+11.5% | Added |
| Ikarian Capital, LLC | 95,955 | $702.4K | 0.16% | −65,182−40.5% | Reduced |
| California State Teachers Retirement System | 98,495 | $721.0K | 0.00% | +258+0.3% | Added |
| Legal & General Group Plc | 101,916 | $746.0K | 0.00% | −134−0.1% | Reduced |
| James J. Burns & Company, LLC | 105,802 | $774.5K | 0.12% | −16,111−13.2% | Reduced |
| New York State Common Retirement Fund | 107,046 | $783.6K | 0.00% | −43,467−28.9% | Reduced |
| Ameriprise Financial Inc | 107,865 | $789.6K | 0.00% | +107,865 | New |
| Cinctive Capital Management LP | 110,537 | $809.1K | 0.04% | −167,227−60.2% | Reduced |
| ADAR1 Capital Management, LLC | 119,067 | $871.6K | 0.09% | +4,253+3.7% | Added |
| Boothbay Fund Management, LLC | 121,162 | $886.9K | 0.02% | −11,729−8.8% | Reduced |
| Manufacturers Life Insurance Company, The | 125,359 | $917.6K | 0.00% | −38,340−23.4% | Reduced |
| Qube Research & Technologies Ltd | 127,983 | $936.8K | 0.00% | −463,401−78.4% | Reduced |
| Man Group plc | 132,771 | $971.9K | 0.00% | +73,492+124.0% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 134,276 | $982.9K | 0.00% | −11,032−7.6% | Reduced |
| Invesco Ltd. | 141,126 | $1.03M | 0.00% | +26,167+22.8% | Added |
| TD Asset Management Inc | 142,408 | $1.04M | 0.00% | −37,200−20.7% | Reduced |
| Rhumbline Advisers | 159,173 | $1.17M | 0.00% | −3,426−2.1% | Reduced |
| Privium Fund Management B.V. | 170,000 | $1.24M | 0.22% | +34,450+25.4% | Added |
| Royal Bank of Canada | 170,498 | $1.25M | 0.00% | +143,663+535.4% | Added |
| Sofinnova Investments, Inc. | 170,943 | $1.25M | 0.08% | +53,040+45.0% | Added |
| Susquehanna International Group, LLP | 196,280 | $1.44M | 0.00% | −28,146−12.5% | Reduced |
| Swiss National Bank | 211,000 | $1.54M | 0.00% | +5,800+2.8% | Added |
| Nuveen, LLC | 249,469 | $1.83M | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 251,700 | $1.84M | 0.00% | +159,400+172.7% | Added |
| Voya Investment Management LLC | 258,011 | $1.89M | 0.00% | +227,167+736.5% | Added |
| Dark Forest Capital Management LP | 262,577 | $1.92M | 0.07% | −18,188−6.5% | Reduced |
| Platinum Investment Management Ltd | 267,794 | $1.96M | 0.13% | −87,559−24.6% | Reduced |
| Barclays PLC | 272,874 | $2.00M | 0.00% | −300,313−52.4% | Reduced |
| Squarepoint Ops LLC | 273,591 | $2.00M | 0.00% | +227,437+492.8% | Added |
| Avidity Partners Management LP | 297,500 | $2.18M | 0.50% | +297,500 | New |
| Bank of New York Mellon Corp | 297,856 | $2.18M | 0.00% | +8,574+3.0% | Added |
| Newtyn Management, LLC | 300,000 | $2.20M | 0.27% | −100,000−25.0% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 305,374 | $2.24M | 0.04% | +20,288+7.1% | Added |
| Ensign Peak Advisors, Inc | 313,307 | $2.29M | 0.00% | 00.0% | Unchanged |
| F/M Investments LLC | 318,087 | $2.33M | 0.09% | +74,410+30.5% | Added |
| Baker Bros. Advisors LP | 344,063 | $2.52M | 0.02% | 00.0% | Unchanged |
| Moody Aldrich Partners LLC | 350,548 | $2.57M | 0.49% | −71,304−16.9% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 368,705 | $2.70M | 0.00% | +10,276+2.9% | Added |
| Millennium Management LLC | 390,749 | $2.86M | 0.00% | −301,666−43.6% | Reduced |
| Wellington Management Group LLP | 429,619 | $3.14M | 0.00% | +131,732+44.2% | Added |
| Morgan Stanley | 507,290 | $3.71M | 0.00% | −1,036,748−67.1% | Reduced |
| Kennedy Capital Management, Inc. | 540,437 | $3.96M | 0.09% | +506,437+1,489.5% | Added |
| Schroder Investment Management Group | 555,544 | $3.96M | 0.00% | −65,834−10.6% | Reduced |
| Two Sigma Investments, LP | 563,004 | $4.12M | 0.01% | +319,837+131.5% | Added |
| Jane Street Group, LLC | 619,641 | $4.54M | 0.01% | +619,641 | New |
| Point72 Asset Management, L.P. | 663,967 | $4.86M | 0.01% | +663,967 | New |
| Bank of America Corp | 665,150 | $4.87M | 0.00% | +19,590+3.0% | Added |
| UBS Group AG | 705,608 | $5.17M | 0.00% | +98,336+16.2% | Added |
| Walleye Capital LLC | 730,639 | $5.35M | 0.04% | +262,752+56.2% | Added |
| JPMorgan Chase & Co | 860,141 | $6.30M | 0.00% | −708,874−45.2% | Reduced |
| RTW Investments, LP | 900,000 | $6.59M | 0.08% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 998,372 | $7.31M | 0.00% | −12,286−1.2% | Reduced |
| Northern Trust Corp | 1,011,750 | $7.41M | 0.00% | +2,968+0.3% | Added |
| Polar Capital Holdings Plc | 1,062,276 | $7.78M | 0.04% | +58,776+5.9% | Added |
| Artisan Partners Limited Partnership | 1,232,926 | $9.03M | 0.01% | −1,031,909−45.6% | Reduced |
| MPM Oncology Impact Management LP | 1,505,262 | $11.0M | 1.80% | 00.0% | Unchanged |
| Emerald Mutual Fund Advisers Trust | 1,766,062 | $12.9M | 0.67% | −171,427−8.8% | Reduced |
| Pfizer Inc | 1,875,000 | $13.7M | 3.14% | 00.0% | Unchanged |
| Primecap Management Co | 1,898,650 | $13.9M | 0.01% | −567,200−23.0% | Reduced |
| Affinity Asset Advisors, LLC | 2,100,000 | $15.4M | 1.43% | +99,692+5.0% | Added |
| StemPoint Capital LP | 2,110,152 | $15.4M | 3.11% | +1,209,814+134.4% | Added |
| Goldman Sachs Group Inc | 2,125,137 | $15.6M | 0.00% | +1,118,056+111.0% | Added |
| State Street Corp | 2,846,366 | $20.8M | 0.00% | +89,611+3.3% | Added |
| Loomis Sayles & Co L P | 2,905,466 | $21.3M | 0.03% | −390,234−11.8% | Reduced |
| Geode Capital Management, LLC | 2,918,370 | $21.4M | 0.00% | +158,989+5.8% | Added |
| Emerald Advisers, LLC | 2,996,900 | $21.9M | 0.70% | −260,219−8.0% | Reduced |
| Vanguard Group Inc | 3,139,836 | $23.0M | 0.00% | −337,241−9.7% | Reduced |
| Siren, L.L.C. | 3,696,322 | $27.1M | 1.06% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 3,750,693 | $27.5M | 0.05% | +3,750,140+678,144.7% | Added |
| Price T Rowe Associates Inc | 4,044,492 | $29.6M | 0.00% | −1,145,911−22.1% | Reduced |
| Bellevue Group AG | 4,094,458 | $30.0M | 0.62% | 00.0% | Unchanged |
| 683 Capital Management, LLC | 4,150,000 | $30.4M | 2.76% | +50,000+1.2% | Added |
| Kynam Capital Management, LP | 4,560,053 | $33.4M | 2.49% | 00.0% | Unchanged |
| FMR LLC | 5,130,374 | $37.6M | 0.00% | +4,511,237+728.6% | Added |
| M28 Capital Management LP | 5,664,548 | $41.5M | 60.97% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 6,298,060 | $46.1M | 0.33% | −233,459−3.6% | Reduced |
| Maverick Capital LtdSuperinvestorMaverick Capital | 8,391,856 | $61.4M | 0.82% | +130,173+1.6% | Added |
| BlackRock, Inc. | 10,430,813 | $76.4M | 0.00% | +47,097+0.5% | Added |
| Adage Capital Partners GP, L.L.C. | 14,567,784 | $106.6M | 0.17% | −448,716−3.0% | Reduced |
| Ra Capital Management, L.P. | 18,202,009 | $133.2M | 1.64% | 00.0% | Unchanged |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −683,193−100.0% | Sold out |
| Woodline Partners LP | 0 | $0 | 0.00% | −452,060−100.0% | Sold out |
| Principal Financial Group Inc | 0 | $0 | 0.00% | −302,276−100.0% | Sold out |
| UBS Asset Management Americas Inc | 0 | $0 | 0.00% | −295,061−100.0% | Sold out |
| D. E. Shaw & Co., Inc. | 0 | $0 | 0.00% | −271,474−100.0% | Sold out |
| Compass Rose Asset Management, LP | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Superstring Capital Management LP | 0 | $0 | 0.00% | −70,242−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −52,728−100.0% | Sold out |
| Birchview Capital, LP | 0 | $0 | 0.00% | −40,300−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −36,089−100.0% | Sold out |
| Nebula Research & Development LLC | 0 | $0 | 0.00% | −34,342−100.0% | Sold out |