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Sionna Therapeutics, Inc.

SION
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0002036042

In the last 90 days, Sionna Therapeutics, Inc. insiders filed 0 open-market purchases and 4 sales; 146 institutions reported holding it in 13F filings for Q2 2026, worth $2.12B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Sionna Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
146
+25 vs. Q1 2026
Shares held
48.3M
+2.64M (+5.8%) vs. Q1 2026
Total value
$2.12B
+$293.5M (+16.1%) vs. Q1 2026
New holders
34
57 more added
Sold out
9
40 more reduced

1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SION on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 146 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 47 institutionsQ2 2025: 65 institutionsQ3 2025: 78 institutionsQ4 2025: 101 institutionsQ1 2026: 122 institutionsQ2 2026: 146 institutions
Value heldQ2 2026: $2.12B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $434.1MQ2 2025: $753.8MQ3 2025: $1.32BQ4 2025: $1.81BQ1 2026: $1.82BQ2 2026: $2.12B
Institutions holding SION and their total value by quarter
QuarterHoldersValue
Q2 2026146$2.12B
Q1 2026122$1.82B
Q4 2025101$1.81B
Q3 202578$1.32B
Q2 202565$753.8M
Q1 202547$434.1M
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Sionna Therapeutics, Inc.; share changes are against Q1 2026.

Institutions holding SION in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.9,905,045$435.7M3.79%00.0%Unchanged
TPG GP A, LLC6,494,962$285.7M5.71%00.0%Unchanged
Viking Global Investors LPSuperinvestorViking Global Investors3,195,181$140.6M0.40%00.0%Unchanged
Atlas Venture Life Science Advisors, LLC2,995,602$131.8M14.95%00.0%Unchanged
OrbiMed Advisors LLC2,555,877$112.4M2.13%−974,825−27.6%Reduced
Enavate Sciences GP, LLC2,478,030$109.0M31.56%00.0%Unchanged
Adage Capital Partners GP, L.L.C.1,600,000$70.4M0.10%+1,450,000+966.7%Added
BlackRock, Inc.1,474,769$64.9M0.00%+178,902+13.8%Added
JPMorgan Chase & Co1,490,508$64.1M0.00%+25,494+1.7%Added
Jennison Associates LLC1,172,133$51.6M0.03%−279,087−19.2%Reduced
Citadel Advisors LLC1,147,636$50.5M0.03%−19,295−1.7%Reduced
Vanguard Capital Management LLC1,132,001$49.8M0.00%+102,504+10.0%Added
State Street Corp1,021,534$44.9M0.00%+265,307+35.1%Added
Perceptive Advisors LLC905,000$39.8M0.62%+246,561+37.4%Added
Deerfield Management Company, L.P. (Series C)680,916$30.0M0.31%−289,674−29.8%Reduced
Siren, L.L.C.610,515$26.9M0.55%+310,515+103.5%Added
Price T Rowe Associates Inc478,016$21.0M0.00%−278,360−36.8%Reduced
Eventide Asset Management, LLC474,981$20.9M0.28%−170,549−26.4%Reduced
Geode Capital Management, LLC457,145$20.1M0.00%+67,273+17.3%Added
Baker Bros. Advisors LP400,000$17.6M0.09%00.0%Unchanged
Casdin Capital, LLC400,000$17.6M0.88%+400,000New
Kalehua Capital Management LLC394,144$17.3M5.53%00.0%Unchanged
Goldman Sachs Group Inc388,810$17.1M0.00%+125,636+47.7%Added
Driehaus Capital Management LLC385,447$17.0M0.10%+308,814+403.0%Added
Franklin Resources Inc290,113$12.8M0.00%+114,630+65.3%Added
Standard Life Aberdeen plc284,138$12.5M0.02%−280,037−49.6%Reduced
FMR LLC278,292$12.2M0.00%+196,897+241.9%Added
Millennium Management LLC276,733$12.2M0.01%+136,092+96.8%Added
Candriam Luxembourg S.C.A.233,208$10.2M0.05%−3,605−1.5%Reduced
Vanguard Portfolio Management LLC222,949$9.81M0.00%+80,868+56.9%Added
Longaeva Partners L.P.196,352$8.64M0.25%+183,659+1,446.9%Added
Artisan Partners Limited Partnership189,498$8.34M0.01%+189,498New
Ensign Peak Advisors, Inc184,532$8.12M0.01%−71,104−27.8%Reduced
Soleus Capital Management, L.P.177,687$7.82M0.27%−115,813−39.5%Reduced
Northern Trust Corp154,476$6.80M0.00%+37,700+32.3%Added
Morgan Stanley151,047$6.64M0.00%+18,024+13.5%Added
Sofinnova Investments, Inc.144,432$6.35M0.34%+144,432New
Qube Research & Technologies Ltd140,309$6.17M0.01%+98,067+232.2%Added
Alyeska Investment Group, L.P.136,222$5.99M0.02%00.0%Unchanged
GordonMD Global Investments LP136,000$5.98M2.89%00.0%Unchanged
Charles Schwab Investment Management Inc129,753$5.71M0.00%+9,500+7.9%Added
Sio Capital Management, LLC127,808$5.62M0.96%−166,532−56.6%Reduced
Vanguard Fiduciary Trust Co121,442$5.34M0.00%+9,267+8.3%Added
Artia Global Partners LP119,741$5.27M1.00%00.0%Unchanged
UBS Group AG116,206$5.11M0.00%−31,435−21.3%Reduced
First Turn Management, LLC110,493$4.86M0.52%+110,493New
Citigroup Inc110,163$4.85M0.00%+92,105+510.1%Added
D. E. Shaw & Co., Inc.101,644$4.47M0.00%+101,644New
Rock Springs Capital Management LP99,429$4.37M0.21%00.0%Unchanged
Walleye Capital LLC97,347$4.28M0.02%+82,250+544.8%Added
Rhenman & Partners Asset Management AB97,100$4.27M0.40%+9,600+11.0%Added
Bank of America Corp88,908$3.91M0.00%+38,038+74.8%Added
Ameriprise Financial Inc82,232$3.62M0.00%+258+0.3%Added
Integral Health Asset Management, LLC75,000$3.30M0.14%+25,000+50.0%Added
Superstring Capital Management LP63,156$2.78M1.75%−77,868−55.2%Reduced
StemPoint Capital LP59,426$2.61M0.45%−13,654−18.7%Reduced
Deutsche Bank AG53,353$2.35M0.00%+40,104+302.7%Added
Seven Grand Managers, LLC50,000$2.20M0.09%00.0%Unchanged
Point72 Asset Management, L.P.49,328$2.17M0.00%−87,221−63.9%Reduced
TD Asset Management Inc47,396$2.08M0.00%−35,600−42.9%Reduced
Alps Advisors Inc45,525$2.00M0.01%+8,897+24.3%Added
Silverarc Capital Management, LLC42,478$1.87M0.21%+3,061+7.8%Added
Russell Investments Group, Ltd.42,258$1.86M0.00%−6,161−12.7%Reduced
Bank of New York Mellon Corp41,586$1.83M0.00%+7,808+23.1%Added
Nuveen, LLC41,259$1.81M0.00%+17,525+73.8%Added
XTX Topco Ltd38,096$1.68M0.02%+14,545+61.8%Added
Wellington Management Group LLP37,365$1.64M0.00%−8,714−18.9%Reduced
Mutual of America Capital Management LLC35,968$1.58M0.02%+35,968New
Manufacturers Life Insurance Company, The35,420$1.56M0.00%−29,038−45.0%Reduced
BNP Paribas Arbitrage, SA31,803$1.40M0.00%−8,767−21.6%Reduced
Ishara Investments LP123,000$1.35M0.99%+73,800+150.0%Added
Swiss National Bank27,000$1.19M0.00%+27,000New
Quadrature Capital Ltd26,023$1.14M0.01%+26,023New
Trexquant Investment LP23,810$1.05M0.01%+23,810New
New York State Common Retirement Fund23,586$1.04M0.00%+18,286+345.0%Added
Alliancebernstein L.P.25,450$1.02M0.00%+9,040+55.1%Added
Tudor Investment Corp Et Al22,575$993.1K0.00%+22,575New
Rhumbline Advisers22,309$981.4K0.00%+4,001+21.9%Added
Maven Securities LTD20,000$879.8K0.06%−5,000−20.0%Reduced
Los Angeles Capital Management LLC18,645$820.2K0.00%+14,529+353.0%Added
Susquehanna Portfolio Strategies, LLC18,034$793.3K0.01%+18,034New
Rafferty Asset Management, LLC18,004$792.0K0.00%−4,133−18.7%Reduced
Shay Capital LLC18,000$791.8K0.09%+18,000New
Wells Fargo & Company16,821$740.0K0.00%+10,927+185.4%Added
Engineers Gate Manager LP15,603$686.4K0.01%+15,603New
California State Teachers Retirement System14,852$653.3K0.00%+13,984+1,611.1%Added
Kennedy Capital Management, Inc.12,621$555.2K0.01%+337+2.7%Added
Marshall Wace, LLP12,599$554.2K0.00%+12,599New
Invesco Ltd.12,418$546.3K0.00%+1,631+15.1%Added
MetLife Investment Management10,972$482.7K0.00%+2,407+28.1%Added
UBS Asset Management Americas Inc10,622$467.3K0.00%+10,506+9,056.9%Added
Mirae Asset Global ETFs Holdings Ltd.10,582$463.4K0.00%+1,397+15.2%Added
Jump Financial, LLC10,473$460.7K0.00%+10,473New
Vanguard Asset Management, Ltd9,535$419.4K0.00%+9,535New
Profund Advisors LLC9,140$402.1K0.01%−799−8.0%Reduced
Virtus Investment Advisers, Inc.9,109$400.7K0.09%+2,735+42.9%Added
Legal & General Group Plc9,044$397.8K0.00%+7,612+531.6%Added
Vanguard Global Advisers, LLC7,852$345.4K0.00%−3,339−29.8%Reduced
China Universal Asset Management Co., Ltd.7,186$316.1K0.02%−734−9.3%Reduced
Quarry LP6,750$296.9K0.05%+446+7.1%Added