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Sionna Therapeutics, Inc.

SION
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0002036042

In the last 90 days, Sionna Therapeutics, Inc. insiders filed 0 open-market purchases and 4 sales; 146 institutions reported holding it in 13F filings for Q2 2026, worth $2.11B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q1 2025

Institutional positions in Sionna Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
47
+47 vs. Q4 2024
Shares held
41.5M
+41.5M vs. Q4 2024
Total value
$434.1M
+$434.1M vs. Q4 2024
New holders
47
0 more added
Sold out
0
0 more reduced

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SION on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 47 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 47 institutionsQ2 2025: 65 institutionsQ3 2025: 78 institutionsQ4 2025: 101 institutionsQ1 2026: 122 institutionsQ2 2026: 146 institutions
Value heldQ1 2025: $434.1M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $434.1MQ2 2025: $753.8MQ3 2025: $1.26BQ4 2025: $1.81BQ1 2026: $1.82BQ2 2026: $2.11B
Institutions holding SION and their total value by quarter
QuarterHoldersValue
Q2 2026146$2.11B
Q1 2026122$1.82B
Q4 2025101$1.81B
Q3 202578$1.26B
Q2 202565$753.8M
Q1 202547$434.1M
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Sionna Therapeutics, Inc.; share changes are against Q4 2024.

Institutions holding SION in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.10,445,322$109.3M1.82%+10,445,322New
TPG GP A, LLC6,684,962$69.9M1.41%+6,684,962New
OrbiMed Advisors LLC3,704,959$38.8M0.93%+3,704,959New
Atlas Venture Life Science Advisors, LLC3,694,020$38.6M7.41%+3,694,020New
Viking Global Investors LPSuperinvestorViking Global Investors2,952,754$30.9M0.10%+2,952,754New
Enavate Sciences GP, LLC2,478,030$25.9M19.53%+2,478,030New
JPMorgan Chase & Co2,169,599$22.7M0.00%+2,169,599New
Perceptive Advisors LLC1,251,101$13.1M0.46%+1,251,101New
Price T Rowe Associates Inc996,212$10.4M0.00%+996,212New
Jennison Associates LLC859,927$8.99M0.01%+859,927New
Deerfield Management Company, L.P. (Series C)747,000$7.81M0.15%+747,000New
Standard Life Aberdeen plc745,964$7.80M0.02%+745,964New
Vanguard Group Inc546,167$5.71M0.00%+546,167New
Franklin Resources Inc500,023$5.23M0.00%+500,023New
Baker Bros. Advisors LP400,000$4.18M0.05%+400,000New
Driehaus Capital Management LLC328,889$3.44M0.03%+328,889New
Citadel Advisors LLC326,500$3.42M0.00%+326,500New
Siren, L.L.C.325,000$3.40M0.19%+325,000New
Soleus Capital Management, L.P.240,000$2.51M0.20%+240,000New
Zimmer Partners, LP237,500$2.48M0.05%+237,500New
Ameriprise Financial Inc209,266$2.19M0.00%+209,266New
BlackRock, Inc.198,396$2.08M0.00%+198,396New
Alyeska Investment Group, L.P.186,222$1.95M0.01%+186,222New
Millennium Management LLC179,072$1.87M0.00%+179,072New
Geode Capital Management, LLC135,563$1.42M0.00%+135,563New
CenterBook Partners LP114,284$1.20M0.08%+114,284New
Silverarc Capital Management, LLC114,138$1.19M0.25%+114,138New
Rock Springs Capital Management LP99,429$1.04M0.06%+99,429New
Woodline Partners LP80,000$836.8K0.01%+80,000New
Charles Schwab Investment Management Inc64,644$676.2K0.00%+64,644New
Goldman Sachs Group Inc63,741$666.7K0.00%+63,741New
Prudential Financial Inc63,000$659.0K0.00%+63,000New
StemPoint Capital LP60,000$627.6K0.20%+60,000New
TD Asset Management Inc55,366$579.1K0.00%+55,366New
Holocene Advisors, LP50,000$523.0K0.00%+50,000New
Squarepoint Ops LLC33,964$355.3K0.00%+33,964New
Manufacturers Life Insurance Company, The33,549$350.9K0.00%+33,549New
Northern Trust Corp26,822$280.6K0.00%+26,822New
Aster Capital Management (DIFC) Ltd14,757$203.2K0.04%+14,757New
State Street Corp14,400$150.6K0.00%+14,400New
Balyasny Asset Management LLC13,060$136.6K0.00%+13,060New
Marshall Wace, LLP12,188$127.5K0.00%+12,188New
Two Sigma Investments, LP11,715$122.5K0.00%+11,715New
UBS Group AG11,146$116.6K0.00%+11,146New
Bank of America Corp8,739$91.4K0.00%+8,739New
Morgan Stanley3,939$41.2K0.00%+3,939New
Royal Bank of Canada618$6.00K0.00%+618New