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Sionna Therapeutics, Inc.

SION
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0002036042

In the last 90 days, Sionna Therapeutics, Inc. insiders filed 0 open-market purchases and 4 sales; 146 institutions reported holding it in 13F filings for Q2 2026, worth $2.11B in total; Viking Global Investors is the only superinvestor holding it.

Holders of 5% or more of SION

Holders whose latest Schedule 13D or 13G filing reports 5% or more of Sionna Therapeutics, Inc., largest stake first. The change is against the holder's previous filing.

Holders of 5% or more of SION
HolderLatest formStakeChangeFirst filedLatest filingFiling
TPG GP A, LLC13D15.20%6.68M sharesNewFeb 18, 20251 filingFeb 18, 2025SEC
Ra Capital Management, L.P.13D/A14.30%6.48M shares−8.30 ppfrom 22.60%Feb 18, 20253 filingsSep 21, 2026SEC
Viking Global Investors LPSuperinvestorViking Global Investors13G/A7.10%3.20M shares+0.40 ppfrom 6.70%Feb 14, 20252 filingsMay 15, 2026SEC
OrbiMed Advisors LLC13D/A6.60%2.97M shares−1.80 ppfrom 8.40%Feb 13, 20252 filingsApr 20, 2026SEC
Enavate Sciences GP, LLC13D5.60%2.48M sharesNewFeb 18, 20251 filingFeb 18, 2025SEC
Atlas Venture Fund XI, L.P.13D/A5.40%2.38M shares−1.10 ppfrom 6.50%Feb 18, 20252 filingsOct 20, 2025SEC

Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.

13D and 13G filings

15 Schedule 13D and 13G filings on Sionna Therapeutics, Inc., newest first, including old-format filings without a stake.

Schedule 13D and 13G filings on SION
Filed (ET)FilerFormStakeChangeEvent dateFiling
Sep 21, 20266:57 PM ETRa Capital Management, L.P.and 4 others13D/A14.30%6.48M shares−8.30 ppfrom 22.60%Sep 17, 2026SEC
May 15, 20265:48 PM ETViking Global Investors LPand 9 othersSuperinvestorViking Global Investors13G/A7.10%3.20M shares+0.40 ppfrom 6.70%Mar 31, 2026SEC
May 12, 20267:39 AM ETQatar Investment Authorityand 1 other13G/A4.50%2.02M shares−0.50 ppfrom 5.00%Below 5%Mar 31, 2026SEC
Apr 20, 20266:46 PM ETOrbiMed Advisors LLCand 1 other13D/A6.60%2.97M shares−1.80 ppfrom 8.40%Apr 15, 2026SEC
Nov 7, 20254:59 PM ETRa Capital Management, L.P.and 4 others13D/A22.60%10.1M shares−1.10 ppfrom 23.70%Nov 5, 2025SEC
Oct 31, 20259:48 AM ETJPMorgan Chase & Co13G/A4.40%1.98M shares−0.60 ppfrom 5.00%Below 5%Sep 30, 2025SEC
Oct 20, 20259:40 PM ETAtlas Venture Fund XI, L.P.and 5 others13D/A5.40%2.38M shares−1.10 ppfrom 6.50%Oct 16, 2025SEC
Jul 30, 20251:19 PM ETJPMorgan Chase & Co13G5.00%2.22M sharesNewJun 30, 2025SEC
Jun 16, 20257:37 AM ETQatar Investment Authorityand 1 other13G5.00%2.21M sharesNewJun 11, 2025SEC
Feb 18, 20258:56 PM ETTPG GP A, LLCand 2 others13D15.20%6.68M sharesNewFeb 10, 2025SEC
Feb 18, 20254:59 PM ETAtlas Venture Fund XI, L.P.and 5 others13D6.50%2.89M sharesNewFeb 10, 2025SEC
Feb 18, 20254:25 PM ETRa Capital Management, L.P.and 4 others13D23.70%10.4M sharesNewFeb 10, 2025SEC
Feb 18, 20254:22 PM ETEnavate Sciences GP, LLCand 1 other13D5.60%2.48M sharesNewFeb 10, 2025SEC
Feb 14, 20254:58 PM ETViking Global Investors LPand 10 othersSuperinvestorViking Global Investors13G6.70%2.95M sharesNewFeb 10, 2025SEC
Feb 13, 20254:47 PM ETOrbiMed Advisors LLCand 1 other13D8.40%3.70M sharesNewFeb 10, 2025SEC

Form 144: proposed insider sales

Notices from officers, directors and other affiliates planning to sell Sionna Therapeutics, Inc. shares.

No Form 144 notices for Sionna Therapeutics, Inc. are on file.