Sionna Therapeutics, Inc.

SION

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0002036042

SEC filings (opens in a new tab)

In the last 90 days, Sionna Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 146 institutions reported holding it in 13F filings for Q2 2026, worth $2.11B in total; Viking Global Investors is the only superinvestor holding it.

Q2 2026 vs. Q1 2026

How the institutions holding Sionna Therapeutics, Inc. changed between Q1 2026 and Q2 2026.

All holders in Q2 2026 All holders in Q1 2026

13F holders of SION: Q1 2026 compared with Q2 2026
Measure	Q1 2026	Of which not filed for Q2 2026	Q2 2026	Change
Holders	122	1	146	+25
Shares	45.4M	67	48.1M	+2.68M (+5.9%)
Value	$1.82B	$2.69K	$2.11B	+$294.2M (+16.2%)

1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (34)

Institutions that held Sionna Therapeutics, Inc. at the end of Q2 2026 but not at the end of Q1 2026.

Institutions new to SION in Q2 2026
Institution	Shares	Value	% of portfolio
Casdin Capital, LLC	400,000	$17.6M	0.88%
Artisan Partners Limited Partnership	189,498	$8.34M	0.01%
Sofinnova Investments, Inc.	144,432	$6.35M	0.34%
First Turn Management, LLC	110,493	$4.86M	0.52%
D. E. Shaw & Co., Inc.	101,644	$4.47M	0.00%
Mutual of America Capital Management LLC	35,968	$1.58M	0.02%
Swiss National Bank	27,000	$1.19M	0.00%
Quadrature Capital Ltd	26,023	$1.14M	0.01%
Trexquant Investment LP	23,810	$1.05M	0.01%
Tudor Investment Corp Et Al	22,575	$993.1K	0.00%
Susquehanna Portfolio Strategies, LLC	18,034	$793.3K	0.01%
Shay Capital LLC	18,000	$791.8K	0.09%
Engineers Gate Manager LP	15,603	$686.4K	0.01%
Marshall Wace, LLP	12,599	$554.2K	0.00%
Jump Financial, LLC	10,473	$460.7K	0.00%
Vanguard Asset Management, Ltd	9,535	$419.4K	0.00%
Jupiter Topco LLC	6,400	$281.0K	0.00%
State Board of Administration of Florida Retirement System	5,215	$229.4K	0.00%
SEI Investments Co	5,158	$226.9K	0.00%
Jain Global LLC	4,780	$210.3K	0.00%
Axq Capital, LP	4,597	$202.2K	0.02%
Vanguard Investments Australia, Ltd.	3,490	$153.5K	0.00%
KLP Kapitalforvaltning AS	3,100	$136.4K	0.00%
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.	1,000	$44.0K	0.00%
State of Wyoming	804	$35.4K	0.00%
Nisa Investment Advisors, LLC	385	$16.9K	0.00%
Pacer Advisors, Inc.	301	$13.0K	0.00%
Federation des caisses Desjardins du Quebec	210	$9.24K	0.00%
Hurley Capital, LLC	113	$4.97K	0.00%
SRS Capital Advisors, Inc.	41	$1.80K	0.00%
Bare Financial Services, Inc	37	$1.63K	0.00%
SJS Investment Consulting Inc.	9	$396	0.00%
Contravisory Investment Management, Inc.	6	$264	0.00%
National Bank of Canada	2	$88	0.00%

Sold out (9)

Institutions that held Sionna Therapeutics, Inc. at the end of Q1 2026 and filed for Q2 2026 without it.

Institutions that sold out of SION in Q2 2026
Institution	Shares, Q1 2026	Value, Q1 2026
Polen Capital Management LLC	26,775	$1.07M
Susquehanna International Group, LLP	7,310	$293.1K
ExodusPoint Capital Management, LP	7,190	$288.2K
Hudson Bay Capital Management LP	6,180	$247.8K
Two Sigma Investments, LP	5,500	$220.5K
Cygnus Capital Advisors, LLC	3,800	$152.0K
Signaturefd, LLC	24	$962
Root Financial Partners, LLC	10	$401
MAI Capital Management	2	$81

Not filed for Q2 2026 yet (1)

Institutions that held Sionna Therapeutics, Inc. at the end of Q1 2026 and haven't filed a 13F for Q2 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding SION in Q1 2026 that haven't filed for Q2 2026
Institution	Shares, Q1 2026	Value, Q1 2026
CWM, LLC	67	$2.69K