Pyxis Oncology, Inc.
PYXS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001782223
No open-market purchases or sales by Pyxis Oncology, Inc. insiders were filed in the last 90 days; 76 institutions reported holding it in 13F filings for Q2 2026, worth $101.1M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Pyxis Oncology, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 78
- 0 vs. Q4 2025
- Shares held
- 27.6M
- −290.4K (−1.0%) vs. Q4 2025
- Total value
- $40.5M
- +$8.48M (+26.5%) vs. Q4 2025
- New holders
- 14
- 11 more added
- Sold out
- 14
- 36 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PYXS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 76 | $101.1M |
| Q1 2026 | 78 | $40.5M |
| Q4 2025 | 79 | $34.7M |
| Q3 2025 | 73 | $59.7M |
| Q2 2025 | 74 | $30.2M |
| Q1 2025 | 89 | $29.6M |
| Q4 2024 | 99 | $49.2M |
| Q3 2024 | 92 | $102.3M |
| Q2 2024 | 80 | $93.1M |
| Q1 2024 | 71 | $97.7M |
| Q4 2023 | 51 | $15.8M |
| Q3 2023 | 54 | $15.4M |
| Q2 2023 | 48 | $24.6M |
| Q1 2023 | 47 | $41.5M |
| Q4 2022 | 31 | $26.5M |
| Q3 2022 | 38 | $38.3M |
| Q2 2022 | 39 | $47.7M |
| Q1 2022 | 45 | $76.1M |
| Q4 2021 | 51 | $199.9M |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Pyxis Oncology, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SBI Securities Co., Ltd. | 1 | $1 | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 4 | $6 | 0.00% | +4 | New |
| Golden State Equity Partners | 10 | $14 | 0.00% | +10 | New |
| SRS Capital Advisors, Inc. | 1 | $20 | 0.00% | −13−92.9% | Reduced |
| CWM, LLC | 34 | $50 | 0.00% | −36−51.4% | Reduced |
| Cornerstone Financial Management LLC | 172 | $251 | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 253 | $369 | 0.00% | −9,537−97.4% | Reduced |
| Wells Fargo & Company | 285 | $416 | 0.00% | −2,000−87.5% | Reduced |
| Jones Financial Companies LLLP | 500 | $655 | 0.00% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 743 | $1.08K | 0.00% | −7,484−91.0% | Reduced |
| UMA Financial Services, Inc. | 943 | $1.38K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 961 | $1.40K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,316 | $1.92K | 0.00% | +39+3.1% | Added |
| BNP Paribas Arbitrage, SA | 1,654 | $2.42K | 0.00% | −22,625−93.2% | Reduced |
| Citigroup Inc | 1,740 | $2.54K | 0.00% | −1,162−40.0% | Reduced |
| Federated Hermes, Inc. | 3,181 | $4.64K | 0.00% | +1,287+68.0% | Added |
| Mirae Asset Global Investments Co., Ltd. | 3,248 | $4.74K | 0.00% | +222+7.3% | Added |
| JPMorgan Chase & Co | 5,173 | $6.57K | 0.00% | −341−6.2% | Reduced |
| Hager Investment Management Services, LLC | 5,000 | $7.30K | 0.00% | +5,000 | New |
| Royal Bank of Canada | 5,839 | $9.00K | 0.00% | −49,712−89.5% | Reduced |
| Winthrop Capital Management, LLC | 6,000 | $9.00K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 6,500 | $9.49K | 0.00% | +6,500 | New |
| GWM Advisors LLC | 10,250 | $15.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 10,332 | $15.1K | 0.00% | −478−4.4% | Reduced |
| China Universal Asset Management Co., Ltd. | 11,049 | $16.1K | 0.00% | +903+8.9% | Added |
| Qube Research & Technologies Ltd | 11,286 | $16.5K | 0.00% | −134,527−92.3% | Reduced |
| Paces Ferry Wealth Advisors, LLC | 11,440 | $16.7K | 0.01% | 00.0% | Unchanged |
| FMR LLC | 11,912 | $17.4K | 0.00% | −946−7.4% | Reduced |
| Two Sigma Securities, LLC | 13,474 | $19.7K | 0.00% | +13,474 | New |
| Advisor Group Holdings, Inc. | 13,721 | $20.0K | 0.00% | −3,503−20.3% | Reduced |
| Bank of America Corp | 16,807 | $24.5K | 0.00% | −571,044−97.1% | Reduced |
| Squarepoint Ops LLC | 17,537 | $25.6K | 0.00% | +17,537 | New |
| Catalyst Funds Management Pty Ltd | 20,400 | $29.8K | 0.01% | +20,400 | New |
| Vanguard Global Advisers, LLC | 21,242 | $31.0K | 0.00% | +21,242 | New |
| Maia Wealth LLC | 21,277 | $31.1K | 0.01% | −682−3.1% | Reduced |
| Graham Capital Management, L.P. | 22,748 | $33.2K | 0.00% | −161,194−87.6% | Reduced |
| Dimensional Fund Advisors LP | 25,912 | $37.8K | 0.00% | −24,154−48.2% | Reduced |
| Cetera Investment Advisers | 27,260 | $39.8K | 0.00% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 32,006 | $46.7K | 0.00% | −156,130−83.0% | Reduced |
| LPL Financial LLC | 33,554 | $49.0K | 0.00% | −1,548−4.4% | Reduced |
| Commonwealth Equity Services, LLC | 34,755 | $50.7K | 0.00% | −5,000−12.6% | Reduced |
| Susquehanna International Group, LLP | 41,201 | $60.2K | 0.00% | −67,213−62.0% | Reduced |
| J. Derek Lewis & Associates Inc. | 43,000 | $62.8K | 0.01% | −10,000−18.9% | Reduced |
| Goldman Sachs Group Inc | 46,920 | $68.5K | 0.00% | −39,225−45.5% | Reduced |
| University of Chicago | 48,731 | $71.1K | 0.02% | 00.0% | Unchanged |
| Barclays PLC | 49,825 | $72.7K | 0.00% | −10,560−17.5% | Reduced |
| Toronto Dominion Bank | 50,000 | $73.0K | 0.00% | −25,000−33.3% | Reduced |
| Stifel Financial Corp | 50,537 | $73.8K | 0.00% | +50,537 | New |
| Citadel Advisors LLC | 61,249 | $89.4K | 0.00% | −182,340−74.9% | Reduced |
| Cable Car Capital LLC | 61,606 | $89.9K | 0.03% | 00.0% | Unchanged |
| Panagora Asset Management Inc | 69,424 | $101.4K | 0.00% | +69,424 | New |
| Morgan Stanley | 69,688 | $101.7K | 0.00% | −19,534−21.9% | Reduced |
| Two Sigma Investments, LP | 73,300 | $107.0K | 0.00% | −32,228−30.5% | Reduced |
| Bridgeway Capital Management, LLC | 81,260 | $118.6K | 0.00% | +8,560+11.8% | Added |
| Northern Trust Corp | 101,948 | $148.8K | 0.00% | 00.0% | Unchanged |
| NewEdge Wealth, LLC | 116,006 | $169.4K | 0.00% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 133,996 | $195.6K | 0.00% | −31,048−18.8% | Reduced |
| Acadian Asset Management LLC | 144,256 | $209.0K | 0.00% | +144,256 | New |
| XTX Topco Ltd | 200,096 | $292.1K | 0.01% | −88,937−30.8% | Reduced |
| State Street Corp | 248,837 | $363.3K | 0.00% | +7,200+3.0% | Added |
| UBS Group AG | 254,124 | $371.0K | 0.00% | −138,642−35.3% | Reduced |
| Vanguard Fiduciary Trust Co | 300,897 | $439.3K | 0.00% | +300,897 | New |
| Jane Street Group, LLC | 304,459 | $444.5K | 0.00% | −481,551−61.3% | Reduced |
| Decheng Capital LLC | 326,810 | $477.1K | 0.07% | 00.0% | Unchanged |
| Marshall Wace, LLP | 354,417 | $517.4K | 0.00% | −35,347−9.1% | Reduced |
| Millennium Management LLC | 397,625 | $580.5K | 0.00% | −345,482−46.5% | Reduced |
| Jacobs Levy Equity Management, Inc | 460,997 | $673.1K | 0.00% | +460,997 | New |
| Longaeva Partners L.P. | 503,214 | $734.7K | 0.04% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 598,121 | $873.8K | 0.00% | +20,910+3.6% | Added |
| BlackRock, Inc. | 788,839 | $1.15M | 0.00% | +4,762+0.6% | Added |
| Renaissance Technologies LLC | 888,680 | $1.30M | 0.00% | +160,300+22.0% | Added |
| 683 Capital Management, LLC | 896,263 | $1.31M | 0.12% | +4,353+0.5% | Added |
| Palo Alto Investors LP | 1,010,510 | $1.48M | 0.23% | −26,911−2.6% | Reduced |
| HealthInvest Partners AB | 197,036 | $1.62M | 0.52% | −420,209−68.1% | Reduced |
| Vanguard Capital Management LLC | 2,033,510 | $2.97M | 0.00% | +2,033,510 | New |
| GordonMD Global Investments LP | 4,121,870 | $6.02M | 4.96% | 00.0% | Unchanged |
| Laurion Capital Management LP | 4,997,333 | $7.30M | 0.68% | +200,854+4.2% | Added |
| Pfizer Inc | 7,032,770 | $9.21M | 3.86% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −317,769−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −100,536−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −67,000−100.0% | Sold out |
| Velan Capital Investment Management LP | 0 | $0 | 0.00% | −40,000−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −39,649−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −31,936−100.0% | Sold out |
| Lighthouse Investment Partners, LLC | 0 | $0 | 0.00% | −28,860−100.0% | Sold out |
| Avanza Fonder AB | 0 | $0 | 0.00% | −27,345−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −22,816−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −22,624−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −22,566−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −16,000−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −94−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −12−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |