Pyxis Oncology, Inc.
PYXS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001782223
In the last 90 days, Pyxis Oncology, Inc. insiders filed 0 open-market purchases and 1 sale; 76 institutions reported holding it in 13F filings for Q2 2026, worth $101.1M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Pyxis Oncology, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 73
- −1 vs. Q2 2025
- Shares held
- 26.8M
- −628.2K (−2.3%) vs. Q2 2025
- Total value
- $59.7M
- +$29.5M (+97.8%) vs. Q2 2025
- New holders
- 14
- 11 more added
- Sold out
- 15
- 31 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PYXS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 76 | $101.1M |
| Q1 2026 | 78 | $40.5M |
| Q4 2025 | 79 | $34.7M |
| Q3 2025 | 73 | $59.7M |
| Q2 2025 | 74 | $30.2M |
| Q1 2025 | 89 | $29.6M |
| Q4 2024 | 99 | $49.2M |
| Q3 2024 | 92 | $102.3M |
| Q2 2024 | 80 | $93.1M |
| Q1 2024 | 71 | $97.7M |
| Q4 2023 | 51 | $15.8M |
| Q3 2023 | 54 | $15.4M |
| Q2 2023 | 48 | $24.6M |
| Q1 2023 | 47 | $41.5M |
| Q4 2022 | 31 | $26.5M |
| Q3 2022 | 38 | $38.3M |
| Q2 2022 | 39 | $47.7M |
| Q1 2022 | 45 | $76.1M |
| Q4 2021 | 51 | $199.9M |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Pyxis Oncology, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SBI Securities Co., Ltd. | 2 | $4 | 0.00% | +1+100.0% | Added |
| Northwestern Mutual Wealth Management Co | 12 | $27 | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 14 | $31 | 0.00% | +14 | New |
| GWM Advisors LLC | 250 | $555 | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 285 | $633 | 0.00% | −414−59.2% | Reduced |
| EverSource Wealth Advisors, LLC | 434 | $964 | 0.00% | −157−26.6% | Reduced |
| CWM, LLC | 414 | $1.00K | 0.00% | −6,122−93.7% | Reduced |
| Jones Financial Companies LLLP | 500 | $1.07K | 0.00% | −1,000−66.7% | Reduced |
| UMA Financial Services, Inc. | 943 | $2.09K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 961 | $2.13K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 1,281 | $2.84K | 0.00% | −7,646−85.7% | Reduced |
| GF Fund Management Co. Ltd. | 1,334 | $2.96K | 0.00% | −95−6.6% | Reduced |
| BNP Paribas Arbitrage, SA | 1,717 | $3.81K | 0.00% | −116−6.3% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,398 | $5.32K | 0.00% | +5+0.2% | Added |
| Barclays PLC | 2,961 | $6.57K | 0.00% | −1,893−39.0% | Reduced |
| JPMorgan Chase & Co | 4,513 | $10.0K | 0.00% | +2,445+118.2% | Added |
| Winthrop Capital Management, LLC | 6,000 | $13.0K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 7,433 | $16.0K | 0.00% | −5,182−41.1% | Reduced |
| Advisor Group Holdings, Inc. | 15,221 | $19.5K | 0.00% | −2,500−14.1% | Reduced |
| China Universal Asset Management Co., Ltd. | 10,871 | $24.1K | 0.00% | −1,571−12.6% | Reduced |
| Tower Research Capital LLC (TRC) | 12,982 | $28.8K | 0.00% | −1,675−11.4% | Reduced |
| AQR Capital Management LLC | 13,832 | $30.7K | 0.00% | −72,931−84.1% | Reduced |
| LPL Financial LLC | 14,002 | $31.1K | 0.00% | −197−1.4% | Reduced |
| HRT Financial LP | 15,398 | $34.0K | 0.00% | −35,270−69.6% | Reduced |
| FMR LLC | 15,455 | $34.3K | 0.00% | −79,391−83.7% | Reduced |
| Prudential Financial Inc | 16,300 | $36.2K | 0.00% | +16,300 | New |
| XTX Topco Ltd | 17,699 | $39.3K | 0.00% | −18,681−51.3% | Reduced |
| Point72 Asia (Singapore) Pte. Ltd. | 18,057 | $40.1K | 0.01% | −1,171−6.1% | Reduced |
| Cetera Investment Advisers | 27,760 | $61.6K | 0.00% | −1,000−3.5% | Reduced |
| Qube Research & Technologies Ltd | 30,808 | $68.4K | 0.00% | −72,255−70.1% | Reduced |
| Cubist Systematic Strategies, LLC | 33,061 | $73.4K | 0.00% | +33,061 | New |
| Persistent Asset Partners Ltd | 34,632 | $76.9K | 0.06% | +34,632 | New |
| Dimensional Fund Advisors LP | 36,516 | $81.1K | 0.00% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 43,082 | $94.0K | 0.00% | +24,140+127.4% | Added |
| Two Sigma Investments, LP | 46,501 | $103.2K | 0.00% | +46,501 | New |
| University of Chicago | 48,731 | $108.2K | 0.05% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 52,524 | $116.6K | 0.00% | +52,524 | New |
| Velan Capital Investment Management LP | 55,000 | $122.1K | 0.11% | +15,000+37.5% | Added |
| Jacobs Levy Equity Management, Inc | 60,333 | $133.9K | 0.00% | +60,333 | New |
| Commonwealth Equity Services, LLC | 61,155 | $136.0K | 0.00% | 00.0% | Unchanged |
| Cable Car Capital LLC | 61,606 | $136.8K | 0.06% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 76,700 | $170.3K | 0.00% | −65,595−46.1% | Reduced |
| Royal Bank of Canada | 77,980 | $173.0K | 0.00% | −8,385−9.7% | Reduced |
| Northern Trust Corp | 100,773 | $223.7K | 0.00% | −1,443−1.4% | Reduced |
| Morgan Stanley | 106,607 | $236.7K | 0.00% | −53,567−33.4% | Reduced |
| Walleye Capital LLC | 119,561 | $265.4K | 0.00% | +119,561 | New |
| Goldman Sachs Group Inc | 125,454 | $278.5K | 0.00% | −98,820−44.1% | Reduced |
| Susquehanna International Group, LLP | 137,531 | $305.3K | 0.00% | +23,172+20.3% | Added |
| Diadema Partners LP | 150,000 | $333.0K | 0.23% | +150,000 | New |
| Pier 88 Investment Partners LLC | 151,730 | $336.8K | 0.06% | −215,440−58.7% | Reduced |
| Bank of New York Mellon Corp | 165,044 | $366.4K | 0.00% | 00.0% | Unchanged |
| State Street Corp | 202,055 | $448.6K | 0.00% | +16,000+8.6% | Added |
| NewEdge Wealth, LLC | 116,006 | $453.6K | 0.01% | 00.0% | Unchanged |
| Schulhoff & Co Inc | 275,000 | $610.5K | 0.26% | 00.0% | Unchanged |
| Jane Street Group, LLC | 303,700 | $674.2K | 0.00% | −32,384−9.6% | Reduced |
| Decheng Capital LLC | 326,810 | $725.5K | 0.13% | 00.0% | Unchanged |
| Citadel Advisors LLC | 337,359 | $748.9K | 0.00% | +337,359 | New |
| UBS Group AG | 373,727 | $829.7K | 0.00% | −22,369−5.6% | Reduced |
| Driehaus Capital Management LLC | 418,632 | $929.4K | 0.01% | +418,632 | New |
| Longaeva Partners L.P. | 503,214 | $1.12M | 0.24% | +503,214 | New |
| 683 Capital Management, LLC | 525,000 | $1.17M | 0.11% | −20,000−3.7% | Reduced |
| Geode Capital Management, LLC | 544,508 | $1.21M | 0.00% | +33,545+6.6% | Added |
| Renaissance Technologies LLC | 576,336 | $1.28M | 0.00% | +158,514+37.9% | Added |
| Bank of America Corp | 615,922 | $1.37M | 0.00% | +593,853+2,690.9% | Added |
| BlackRock, Inc. | 683,702 | $1.52M | 0.00% | −243,103−26.2% | Reduced |
| StemPoint Capital LP | 689,538 | $1.53M | 0.31% | +689,538 | New |
| Millennium Management LLC | 815,331 | $1.81M | 0.00% | −2,724,529−77.0% | Reduced |
| Palo Alto Investors LP | 1,037,421 | $2.30M | 0.43% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 1,178,307 | $2.62M | 0.08% | +1,178,307 | New |
| Vanguard Group Inc | 2,163,962 | $4.80M | 0.00% | +14,566+0.7% | Added |
| Tang Capital Management LLC | 2,500,000 | $5.55M | 0.21% | 00.0% | Unchanged |
| Laurion Capital Management LP | 3,625,974 | $8.05M | 1.10% | 00.0% | Unchanged |
| Pfizer Inc | 7,032,770 | $15.6M | 3.57% | 00.0% | Unchanged |
| Standard Life Aberdeen plc | 0 | $0 | 0.00% | −913,045−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −147,771−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −133,047−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −48,649−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −35,428−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −23,200−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −13,790−100.0% | Sold out |
| DRW Securities, LLC | 0 | $0 | 0.00% | −13,042−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −12,334−100.0% | Sold out |
| Mercer Global Advisors Inc | 0 | $0 | 0.00% | −10,004−100.0% | Sold out |
| Raymond James Financial Inc | 0 | $0 | 0.00% | −3,231−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −602−100.0% | Sold out |
| True Wealth Design, LLC | 0 | $0 | 0.00% | −276−100.0% | Sold out |
| Russell Investments Group, Ltd. | 0 | $0 | 0.00% | −64−100.0% | Sold out |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −1−100.0% | Sold out |