| Apr 28, 2023 (view filing) | Apr 26 | 2 days | Malecek Michael JChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $53.45 | −$267.3K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 21, 2023 (view filing) | Apr 19 | 2 days | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $52.89 | −$264.5K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 31, 2023 (view filing) | Mar 29 | 2 days | Malecek Michael JChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $49.02 | −$245.1K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 22, 2023 (view filing) | Mar 20 | 2 days | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $47.72 | −$238.6K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 17, 2023 (view filing) | Mar 15 | 2 days | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −20.0K | $48.41 | −$968.3K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 17, 2023 (view filing) | Mar 15 | 2 days | Nguyen TranChief Strategy Officer and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −10.0K | $48.43 | −$484.3K | −75.8%3.20K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 17, 2023 (view filing) | Mar 15 | 2 days | Malecek Michael JChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −15.0K | $48.44 | −$726.6K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 17, 2023 (view filing) | Mar 15 | 2 days | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −12.0K | $48.41 | −$580.9K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 17, 2023 (view filing) | Feb 15 | 2 days | Nguyen TranChief Strategy Officer and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −10.0K | $53.34 | −$533.4K | −75.8%3.20K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 20, 2023 (view filing) | Jan 18 | 2 days | Nguyen TranChief Strategy Officer and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −10.0K | $55.53 | −$555.3K | −75.8%3.20K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 12, 2023 (view filing) | Jan 10 | 2 days | Cooke ShaneDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $52.92 | −$264.6K | −100.0%0 after | |
| Jan 5, 2023 (view filing) | Jan 3 | 2 days | Ekman LarsDirector, Other: Chair of the Board | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −15.8K | $55.98 | −$886.4K | −98.5%243 after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 5, 2023 (view filing) | Jan 5 | Same day | Collier Richard TDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $52.67 | −$263.4K | −80.4%1.22K after | |
| Dec 23, 2022 (view filing) | Dec 21 | 2 days | Nguyen TranChief Strategy Officer and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −10.0K | $58.97 | −$589.7K | −75.8%3.20K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 12, 2022 (view filing) | Dec 12 | Same day | Cooke ShaneDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $61.04 | −$305.2K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 5, 2022 (view filing) | Dec 5 | Same day | Collier Richard TDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $62.07 | −$310.4K | −80.4%1.22K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 2, 2022 (view filing) | Nov 30 | 2 days | Malecek Michael JChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $62.28 | −$311.4K | −100.0%0 after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 2, 2022 (view filing) | Dec 1 | 1 day | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.00K | $62.51 | −$250.0K | −100.0%0 after | |
| Dec 2, 2022 (view filing) | Dec 1 | 1 day | Ekman LarsDirector, Other: Chair of the Board | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −15.8K | $61.60 | −$975.4K | −98.5%243 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 25, 2022 (view filing) | Nov 23 | 2 days | Nguyen TranChief Strategy Officer and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −10.0K | $61.09 | −$610.9K | −75.8%3.20K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 18, 2022 (view filing) | Nov 18 | Same day | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −10.0K | $57.07 | −$570.7K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 10, 2022 (view filing) | Nov 10 | Same day | Cooke ShaneDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $56.17 | −$280.8K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 9, 2022 (view filing) | Nov 7 | 2 days | Collier Richard TDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $55.62 | −$278.1K | −80.4%1.22K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 3, 2022 (view filing) | Nov 1 | 2 days | Ekman LarsDirector, Other: Chair of the Board | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −15.8K | $62.89 | −$995.7K | −98.5%243 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 3, 2022 (view filing) | Nov 1 | 2 days | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.00K | $61.90 | −$247.6K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 28, 2022 (view filing) | Oct 26-27 | 2 days | Malecek Michael JChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −85.0K | $60.71 | −$5.16M | −100.0%0 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 26, 2022 (view filing) | Oct 24 | 2 days | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −20.0K | $57.23 | −$1.14M | −100.0%0 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 21, 2022 (view filing) | Oct 19 | 2 days | Nguyen TranChief Strategy Officer and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −10.0K | $56.44 | −$564.4K | −75.8%3.20K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 12, 2022 (view filing) | Oct 10 | 2 days | Cooke ShaneDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $55.91 | −$279.6K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 7, 2022 (view filing) | Oct 5 | 2 days | Collier Richard TDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $57.92 | −$289.6K | −80.4%1.22K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 5, 2022 (view filing) | Oct 3 | 2 days | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.00K | $60.90 | −$243.6K | −100.0%0 after | |
| Oct 5, 2022 (view filing) | Oct 3 | 2 days | Ekman LarsDirector, Other: Chair of the Board | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −15.8K | $61.52 | −$974.1K | −98.5%243 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 30, 2022 (view filing) | Sep 28 | 2 days | Kinney Gene G.President and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −16.4K | $53.38 | −$876.0K | −56.2%12.8K after | 10 lotsThis row combines 10 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 30, 2022 (view filing) | Sep 28 | 2 days | Cooke ShaneDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −10.0K | $48.09 | −$480.9K | −100.0%0 after | |
| Sep 30, 2022 (view filing) | Sep 28 | 2 days | Collier Richard TDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −25.0K | $48.09 | −$1.20M | −95.4%1.22K after | |
| Sep 30, 2022 (view filing) | Sep 28 | 2 days | Ekman LarsDirector, Other: Chair of the Board | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −31.7K | $48.09 | −$1.52M | −99.2%243 after | |
| Sep 23, 2022 (view filing) | Sep 21 | 2 days | Kinney Gene G.President and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −2.72K | $32.02 | −$87.1K | −17.5%12.8K after | |
| Sep 23, 2022 (view filing) | Sep 21 | 2 days | Nguyen TranChief Strategy Officer and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −10.0K | $30.75 | −$307.5K | −75.8%3.20K after | |
| Sep 16, 2022 (view filing) | Sep 15 | 1 day | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.00K | $30.00 | −$120.0K | −100.0%0 after | |
| Aug 26, 2022 (view filing) | Aug 24 | 2 days | Nguyen TranChief Strategy Officer and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −10.0K | $30.17 | −$301.7K | −75.8%3.20K after | |
| Aug 19, 2022 (view filing) | Aug 17 | 2 days | Kinney Gene G.President and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −2.18K | $32.03 | −$69.9K | −14.6%12.8K after | |
| Aug 12, 2022 (view filing) | Aug 10-12 | 2 days | Kinney Gene G.President and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −34.9K | $32.16 | −$1.12M | −73.2%12.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 5, 2022 (view filing) | Aug 4-5 | 1 day | Kinney Gene G.President and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −42.5K | $32.51 | −$1.38M | −76.8%12.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 3, 2022 (view filing) | Aug 1 | 2 days | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.00K | $30.52 | −$122.1K | −100.0%0 after | |
| Jul 29, 2022 (view filing) | Jul 27 | 2 days | Kinney Gene G.President and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −376 | $32.00 | −$12.0K | −2.9%12.8K after | |
| Jul 22, 2022 (view filing) | Jul 20-22 | 2 days | Nguyen TranChief Strategy Officer and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −70.0K | $32.54 | −$2.28M | −95.6%3.20K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 22, 2022 (view filing) | Jul 20 | 2 days | Cooke ShaneDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −15.0K | $32.90 | −$493.5K | −100.0%0 after | |
| Jul 8, 2022 (view filing) | Jul 6 | 2 days | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −8.00K | $30.00 | −$240.0K | −100.0%0 after | |
| May 9, 2022 (view filing) | May 5 | 4 days | EcoR1 Capital, LLC10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1.06M | $29.02 | +$30.8M | +10.1%11.6M after | |
| May 9, 2022 (view filing) | May 5 | 4 days | EcoR1 Capital, LLC10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.06M | $29.02 | −$30.8M | −8.4%11.6M after | |
