| Sep 21, 2026 (view filing)4:23 PM ET | Sep 18 | 3 days | Scully William P10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares, par value $0.01 per share | +100.0K | $8.43 | +$843.5K | +12.1%927.0K after | |
| Sep 3, 2026 (view filing)6:23 PM ET | Sep 2 | 1 day | Scully William P10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares, par value $0.01 per share | +27.0K | $9.47 | +$255.7K | +3.4%827.0K after | |
| Aug 21, 2026 (view filing)2:32 PM ET | Aug 20 | 1 day | Scully William P10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares, par value $0.01 per share | +50.0K | $8.79 | +$439.4K | +6.7%800.0K after | |
| Aug 10, 2026 (view filing)3:24 PM ET | Aug 7 | 3 days | Scully William P10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares, par value $0.01 per share | +34.0K | $8.62 | +$293.1K | +4.5%790.0K after | |
| Aug 10, 2026 (view filing)3:24 PM ET | Aug 7 | 3 days | Scully William P10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares, par value $0.01 per share | +3.50K | $8.62 | +$30.2K | +4.4%83.5K after | |
| Jul 30, 2026 (view filing)8:31 PM ET | Jul 29 | 1 day | Kingston Anne EvansChief Strategy Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −7.66K | $8.47 | −$64.9K | −12.1%55.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 30, 2026 (view filing)8:30 PM ET | Jul 29 | 1 day | Isaacs Michael JohnGeneral Counsel & Company Sec. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −8.39K | $8.47 | −$71.1K | −19.0%35.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 18, 2026 (view filing) | Jun 16 | 2 days | Scully William P10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares, par value $0.01 per share | +20.0K | $7.90 | +$158.0K | +2.7%756.0K after | |
| Jun 12, 2026 (view filing) | Jun 11 | 1 day | Scully William P10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares, par value $0.01 per share | +125.0K | $8.17 | +$1.02M | +13.4%1.06M after | |
| Jun 5, 2026 (view filing) | Jun 4 | 1 day | Scully William P10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares, par value $0.01 per share | +50.0K | $9.31 | +$465.5K | +5.6%936.0K after | |
| Jun 3, 2026 (view filing) | Jun 2 | 1 day | Scully William P10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares, par value $0.01 per share | +50.0K | $9.43 | +$471.5K | +6.0%886.0K after | |
| May 26, 2026 (view filing) | May 22 | 4 days | Scully William P10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares, par value $0.01 per share | +100.0K | $9.81 | +$981.0K | +13.6%836.0K after | |
| May 6, 2025 (view filing) | May 2-6 | 4 days | EcoR1 Capital, LLC10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.28M | $8.09 | −$50.8M | −54.2%5.30M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| May 2, 2025 (view filing) | Dec 18, 2024-Jan 14, 2025 | 135 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Scully William P10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Ordinary Shares, par value $0.01 per share | +207.4K | $13.26 | +$2.75M | +39.2%736.0K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 24, 2024 (view filing) | Jan 24 | Same day | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $34.00 | −$170.0K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 20, 2023 (view filing) | Dec 20 | Same day | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $37.19 | −$186.0K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 30, 2023 (view filing) | Nov 30 | Same day | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $34.00 | −$170.0K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 25, 2023 (view filing) | Oct 25 | Same day | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $41.04 | −$205.2K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 11, 2023 (view filing) | Oct 11 | Same day | Smith Brandon S.Chief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.00K | $46.74 | −$187.0K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 4, 2023 (view filing) | Oct 4 | Same day | Karp Carol D.Chief Regulatory Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $46.61 | −$233.1K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 27, 2023 (view filing) | Sep 27 | Same day | Malecek Michael JChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $47.37 | −$236.9K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 19, 2023 (view filing) | Sep 19 | Same day | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $52.36 | −$261.8K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 13, 2023 (view filing) | Sep 13 | Same day | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −2.00K | $55.48 | −$111.0K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 13, 2023 (view filing) | Sep 13 | Same day | Smith Brandon S.Chief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.00K | $55.49 | −$222.0K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 6, 2023 (view filing) | Sep 6 | Same day | Karp Carol D.Chief Regulatory Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $54.76 | −$273.8K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 30, 2023 (view filing) | Aug 30 | Same day | Malecek Michael JChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $55.02 | −$275.1K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 18, 2023 (view filing) | Aug 18 | Same day | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $57.18 | −$285.9K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 16, 2023 (view filing) | Aug 16 | Same day | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −2.00K | $58.74 | −$117.5K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 16, 2023 (view filing) | Aug 16 | Same day | Smith Brandon S.Chief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.00K | $58.71 | −$234.8K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 2, 2023 (view filing) | Aug 2 | Same day | Zago Wagner M.Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.00K | $67.04 | −$268.2K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 2, 2023 (view filing) | Aug 2 | Same day | Karp Carol D.Chief Regulatory Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $67.02 | −$335.1K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 26, 2023 (view filing) | Jul 26 | Same day | Malecek Michael JChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $62.33 | −$311.6K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 19, 2023 (view filing) | Jul 19 | Same day | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $69.19 | −$346.0K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 12, 2023 (view filing) | Jul 12 | Same day | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −2.00K | $67.51 | −$135.0K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 12, 2023 (view filing) | Jul 12 | Same day | Smith Brandon S.Chief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.00K | $67.51 | −$270.0K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 5, 2023 (view filing) | Jul 5 | Same day | Karp Carol D.Chief Regulatory Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $68.13 | −$340.6K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 5, 2023 (view filing) | Jul 5 | Same day | Zago Wagner M.Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.00K | $68.16 | −$272.6K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 3, 2023 (view filing) | Jul 3 | Same day | Selkoe Dennis J.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $67.43 | −$337.1K | −63.7%2.85K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 28, 2023 (view filing) | Jun 28 | Same day | Malecek Michael JChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $69.82 | −$349.1K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 20, 2023 (view filing) | Jun 20 | Same day | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $68.90 | −$344.5K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 16, 2023 (view filing) | Jun 16 | Same day | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −7.33K | $74.00 | −$542.5K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 14, 2023 (view filing) | Jun 14 | Same day | Smith Brandon S.Chief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.33K | $73.98 | −$394.6K | −100.0%0 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 14, 2023 (view filing) | Jun 14 | Same day | Garren HidekiChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −4.67K | $74.22 | −$346.5K | −100.0%0 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 7, 2023 (view filing) | Jun 7 | Same day | Zago Wagner M.Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −19.0K | $71.06 | −$1.35M | −100.0%0 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 7, 2023 (view filing) | Jun 7 | Same day | Karp Carol D.Chief Regulatory Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −20.0K | $71.05 | −$1.42M | −100.0%0 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 31, 2023 (view filing) | May 31 | Same day | Malecek Michael JChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $64.64 | −$323.2K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 19, 2023 (view filing) | May 19 | Same day | Walker Karin LChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −5.00K | $74.00 | −$370.0K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 17, 2023 (view filing) | May 17 | Same day | Kinney Gene G.President and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −45.0K | $73.69 | −$3.32M | −77.9%12.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 17, 2023 (view filing) | May 17 | Same day | Nguyen TranChief Strategy Officer and CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −95.0K | $73.99 | −$7.03M | −96.7%3.20K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 5, 2023 (view filing) | May 3 | 2 days | Selkoe Dennis J.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Ordinary Shares, par value $0.01 per share | −15.0K | $57.00 | −$855.0K | −84.1%2.85K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
