ProQR Therapeutics N.V.
PRQR- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001612940
In the last 90 days, ProQR Therapeutics N.V. insiders filed 5 open-market purchases and 0 sales; 70 institutions reported holding it in 13F filings for Q2 2026, worth $113.0M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in ProQR Therapeutics N.V. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 65
- +2 vs. Q3 2025
- Shares held
- 37.2M
- −334.9K (−0.9%) vs. Q3 2025
- Total value
- $75.1M
- −$4.80M (−6.0%) vs. Q3 2025
- New holders
- 10
- 23 more added
- Sold out
- 8
- 10 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRQR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 70 | $113.0M |
| Q1 2026 | 69 | $56.8M |
| Q4 2025 | 65 | $75.1M |
| Q3 2025 | 64 | $80.0M |
| Q2 2025 | 62 | $82.4M |
| Q1 2025 | 65 | $54.9M |
| Q4 2024 | 77 | $117.7M |
| Q3 2024 | 47 | $31.7M |
| Q2 2024 | 48 | $28.6M |
| Q1 2024 | 49 | $39.8M |
| Q4 2023 | 47 | $37.0M |
| Q3 2023 | 46 | $24.3M |
| Q2 2023 | 51 | $34.2M |
| Q1 2023 | 55 | $47.5M |
| Q4 2022 | 46 | $60.0M |
| Q3 2022 | 47 | $15.9M |
| Q2 2022 | 51 | $17.2M |
| Q1 2022 | 58 | $28.7M |
| Q4 2021 | 74 | $364.8M |
| Q3 2021 | 67 | $333.4M |
| Q2 2021 | 63 | $259.4M |
| Q1 2021 | 64 | $286.4M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding ProQR Therapeutics N.V.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Adage Capital Partners GP, L.L.C. | 6,253,467 | $12.6M | 0.02% | 00.0% | Unchanged |
| Privium Fund Management B.V. | 5,357,762 | $10.8M | 1.99% | +359,475+7.2% | Added |
| Standard Life Aberdeen plc | 2,950,676 | $5.96M | 0.01% | +651,853+28.4% | Added |
| Affinity Asset Advisors, LLC | 2,454,278 | $4.96M | 0.36% | −1,145,722−31.8% | Reduced |
| Sio Capital Management, LLC | 2,164,181 | $4.37M | 0.72% | +89,042+4.3% | Added |
| DAFNA Capital Management LLC | 1,567,561 | $3.17M | 0.74% | 00.0% | Unchanged |
| Kynam Capital Management, LP | 1,566,317 | $3.16M | 0.21% | −83,145−5.0% | Reduced |
| Ikarian Capital, LLC | 1,492,229 | $3.01M | 0.39% | +600,000+67.2% | Added |
| Morgan Stanley | 1,367,119 | $2.76M | 0.00% | −1,534,083−52.9% | Reduced |
| Platinum Investment Management Ltd | 1,235,514 | $2.50M | 0.58% | 00.0% | Unchanged |
| ArrowMark Colorado Holdings LLC | 1,164,722 | $2.35M | 0.05% | −81,512−6.5% | Reduced |
| M28 Capital Management LP | 1,019,498 | $2.06M | 1.50% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 839,384 | $1.70M | 0.00% | +422,084+101.1% | Added |
| Point72 Asset Management, L.P. | 813,650 | $1.64M | 0.00% | +63,650+8.5% | Added |
| UBS Group AG | 797,664 | $1.61M | 0.00% | +703,114+743.6% | Added |
| Nomura Asset Management International Inc. | 620,000 | $1.25M | 0.00% | +620,000 | New |
| Walleye Capital LLC | 591,785 | $1.20M | 0.01% | +59,808+11.2% | Added |
| Citadel Advisors LLC | 583,222 | $1.18M | 0.00% | −73,790−11.2% | Reduced |
| Two Sigma Advisers, LP | 452,400 | $913.8K | 0.00% | +223,800+97.9% | Added |
| Millennium Management LLC | 434,991 | $878.7K | 0.00% | +194,369+80.8% | Added |
| Monaco Asset Management SAM | 428,803 | $866.2K | 0.26% | −31,197−6.8% | Reduced |
| Boothbay Fund Management, LLC | 355,283 | $717.7K | 0.02% | +106,993+43.1% | Added |
| Raymond James Financial Inc | 342,886 | $692.6K | 0.00% | +232,616+211.0% | Added |
| Northern Trust Corp | 294,742 | $595.4K | 0.00% | 00.0% | Unchanged |
| Palo Alto Investors LP | 188,807 | $381.4K | 0.05% | 00.0% | Unchanged |
| Bank of America Corp | 173,924 | $351.3K | 0.00% | +54,726+45.9% | Added |
| Diadema Partners LP | 167,532 | $338.4K | 0.20% | +9,838+6.2% | Added |
| Jane Street Group, LLC | 160,175 | $323.6K | 0.00% | +149,414+1,388.5% | Added |
| BNP Paribas Arbitrage, SA | 157,149 | $317.4K | 0.00% | +17,555+12.6% | Added |
| Franklin Street Advisors Inc | 150,000 | $303.0K | 0.02% | 00.0% | Unchanged |
| XTX Topco Ltd | 117,900 | $238.2K | 0.01% | +107,713+1,057.4% | Added |
| Deutsche Bank AG | 108,762 | $219.7K | 0.00% | 00.0% | Unchanged |
| Quadrature Capital Ltd | 104,231 | $210.5K | 0.00% | +68,091+188.4% | Added |
| Resources Investment Advisors, LLC. | 85,000 | $171.7K | 0.00% | +5,000+6.3% | Added |
| Geode Capital Management, LLC | 84,909 | $171.5K | 0.00% | +36,087+73.9% | Added |
| Lynx1 Capital Management LP | 68,486 | $138.3K | 0.03% | +68,486 | New |
| Persistent Asset Partners Ltd | 45,154 | $91.2K | 0.04% | +8,874+24.5% | Added |
| Velan Capital Investment Management LP | 45,000 | $90.9K | 0.05% | 00.0% | Unchanged |
| Simplex Trading, LLC | 44,269 | $89.4K | 0.00% | +44,269 | New |
| Group One Trading, L.P. | 30,388 | $61.4K | 0.00% | +30,388 | New |
| Fifth Third Bancorp | 30,000 | $60.6K | 0.00% | 00.0% | Unchanged |
| RFG Advisory, LLC | 30,000 | $60.6K | 0.00% | 00.0% | Unchanged |
| Invesco Ltd. | 25,347 | $51.2K | 0.00% | +25,347 | New |
| Moody Lynn & Lieberson, LLC | 25,000 | $50.5K | 0.00% | +25,000 | New |
| JustInvest LLC | 22,314 | $45.1K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 20,097 | $40.6K | 0.00% | +570+2.9% | Added |
| Keating Financial Advisory Services, Inc. | 20,000 | $40.4K | 0.01% | +20,000 | New |
| Mariner, LLC | 19,219 | $38.8K | 0.00% | 00.0% | Unchanged |
| Guggenheim Capital LLC | 17,224 | $34.8K | 0.00% | +17,224 | New |
| Atom Investors LP | 13,107 | $26.5K | 0.00% | 00.0% | Unchanged |
| Truist Financial Corp | 10,000 | $20.2K | 0.00% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 10,000 | $20.2K | 0.00% | 00.0% | Unchanged |
| Nano Cap New Millennium Growth Fund L P | 10,000 | $20.2K | 0.02% | +10,000 | New |
| Royal Bank of Canada | 10,303 | $20.0K | 0.00% | −81,904−88.8% | Reduced |
| Wells Fargo & Company | 4,000 | $8.08K | 0.00% | −1,610−28.7% | Reduced |
| BlackRock, Inc. | 3,945 | $7.97K | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 1,300 | $2.63K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 1,211 | $2.45K | 0.00% | +318+35.6% | Added |
| PFS Partners, LLC | 1,000 | $2.02K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 1,000 | $2.02K | 0.00% | +1,000 | New |
| SBI Securities Co., Ltd. | 515 | $1.04K | 0.00% | −37−6.7% | Reduced |
| JPMorgan Chase & Co | 283 | $572 | 0.00% | −185−39.5% | Reduced |
| TD Waterhouse Canada Inc. | 40 | $80 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 34 | $69 | 0.00% | 00.0% | Unchanged |
| Medallion Wealth Advisors, LLC | 10 | $20 | 0.00% | 00.0% | Unchanged |
| Siren, L.L.C. | 0 | $0 | 0.00% | −1,552,183−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −620,000−100.0% | Sold out |
| Woodline Partners LP | 0 | $0 | 0.00% | −92,140−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −25,245−100.0% | Sold out |
| Citigroup Inc | 0 | $0 | 0.00% | −22,724−100.0% | Sold out |
| Kestra Advisory Services, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Advisor Group Holdings, Inc. | 0 | $0 | 0.00% | −6,000−100.0% | Sold out |
| Activest Wealth Management | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |