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ProQR Therapeutics N.V.

PRQR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001612940

In the last 90 days, ProQR Therapeutics N.V. insiders filed 5 open-market purchases and 0 sales; 70 institutions reported holding it in 13F filings for Q2 2026, worth $113.0M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in ProQR Therapeutics N.V. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
69
+4 vs. Q4 2025
Shares held
35.1M
−2.07M (−5.6%) vs. Q4 2025
Total value
$56.8M
−$18.2M (−24.3%) vs. Q4 2025
New holders
10
14 more added
Sold out
6
16 more reduced

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRQR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 69 institutions
Q1 2021: 64 institutionsQ2 2021: 63 institutionsQ3 2021: 67 institutionsQ4 2021: 74 institutionsQ1 2022: 58 institutionsQ2 2022: 51 institutionsQ3 2022: 47 institutionsQ4 2022: 46 institutionsQ1 2023: 55 institutionsQ2 2023: 51 institutionsQ3 2023: 46 institutionsQ4 2023: 47 institutionsQ1 2024: 49 institutionsQ2 2024: 48 institutionsQ3 2024: 47 institutionsQ4 2024: 77 institutionsQ1 2025: 65 institutionsQ2 2025: 62 institutionsQ3 2025: 64 institutionsQ4 2025: 65 institutionsQ1 2026: 69 institutionsQ2 2026: 70 institutions
Value heldQ1 2026: $56.8M
Q1 2021: $286.4MQ2 2021: $259.4MQ3 2021: $333.4MQ4 2021: $364.8MQ1 2022: $28.7MQ2 2022: $17.2MQ3 2022: $15.9MQ4 2022: $60.0MQ1 2023: $47.5MQ2 2023: $34.2MQ3 2023: $24.3MQ4 2023: $37.0MQ1 2024: $39.8MQ2 2024: $28.6MQ3 2024: $31.7MQ4 2024: $117.7MQ1 2025: $54.9MQ2 2025: $82.4MQ3 2025: $80.0MQ4 2025: $75.1MQ1 2026: $56.8MQ2 2026: $113.0M
Institutions holding PRQR and their total value by quarter
QuarterHoldersValue
Q2 202670$113.0M
Q1 202669$56.8M
Q4 202565$75.1M
Q3 202564$80.0M
Q2 202562$82.4M
Q1 202565$54.9M
Q4 202477$117.7M
Q3 202447$31.7M
Q2 202448$28.6M
Q1 202449$39.8M
Q4 202347$37.0M
Q3 202346$24.3M
Q2 202351$34.2M
Q1 202355$47.5M
Q4 202246$60.0M
Q3 202247$15.9M
Q2 202251$17.2M
Q1 202258$28.7M
Q4 202174$364.8M
Q3 202167$333.4M
Q2 202163$259.4M
Q1 202164$286.4M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding ProQR Therapeutics N.V.; share changes are against Q4 2025.

Institutions holding PRQR in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Adage Capital Partners GP, L.L.C.6,253,467$10.1M0.02%00.0%Unchanged
Privium Fund Management B.V.5,467,149$8.86M1.84%+109,387+2.0%Added
Standard Life Aberdeen plc3,316,965$5.37M0.01%+366,289+12.4%Added
Affinity Asset Advisors, LLC2,454,278$3.98M0.23%00.0%Unchanged
Sio Capital Management, LLC1,954,715$3.17M0.46%−209,466−9.7%Reduced
DAFNA Capital Management LLC1,567,561$2.54M0.58%00.0%Unchanged
Kynam Capital Management, LP1,566,317$2.54M0.16%00.0%Unchanged
Ikarian Capital, LLC1,492,229$2.42M0.35%00.0%Unchanged
Morgan Stanley1,299,775$2.11M0.00%−67,344−4.9%Reduced
Platinum Investment Management Ltd1,235,514$2.00M0.50%00.0%Unchanged
Two Sigma Investments, LP918,857$1.49M0.00%+79,473+9.5%Added
Point72 Asset Management, L.P.755,842$1.22M0.00%−57,808−7.1%Reduced
Citadel Advisors LLC703,323$1.14M0.00%+120,101+20.6%Added
Nomura Asset Management International Inc.620,000$1.00M0.00%00.0%Unchanged
Walleye Capital LLC607,529$984.2K0.01%+15,744+2.7%Added
M28 Capital Management LP599,793$971.7K1.81%−419,705−41.2%Reduced
Raymond James Financial Inc546,079$884.6K0.00%+203,193+59.3%Added
Monaco Asset Management SAM418,803$678.5K0.22%−10,000−2.3%Reduced
Boothbay Fund Management, LLC355,283$575.6K0.01%00.0%Unchanged
UBS Group AG305,264$494.5K0.00%−492,400−61.7%Reduced
Northern Trust Corp291,314$471.9K0.00%−3,428−1.2%Reduced
Millennium Management LLC194,246$314.7K0.00%−240,745−55.3%Reduced
Palo Alto Investors LP188,807$305.9K0.05%00.0%Unchanged
Bank of America Corp185,110$299.9K0.00%+11,186+6.4%Added
Diadema Partners LP180,083$291.7K0.12%+12,551+7.5%Added
BNP Paribas Arbitrage, SA172,349$279.2K0.00%+15,200+9.7%Added
Franklin Street Advisors Inc150,000$243.0K0.01%00.0%Unchanged
Marshall Wace, LLP115,945$187.8K0.00%+115,945New
Gsa Capital Partners LLP114,256$185.0K0.01%+114,256New
Deutsche Bank AG108,762$176.2K0.00%00.0%Unchanged
Graham Capital Management, L.P.91,553$148.3K0.01%+91,553New
Resources Investment Advisors, LLC.85,000$137.7K0.00%00.0%Unchanged
Geode Capital Management, LLC84,909$137.6K0.00%00.0%Unchanged
XTX Topco Ltd77,287$125.2K0.00%−40,613−34.4%Reduced
Lynx1 Capital Management LP68,486$110.9K0.02%00.0%Unchanged
Persistent Asset Partners Ltd46,067$74.6K0.03%+913+2.0%Added
Velan Capital Investment Management LP45,000$72.9K0.05%00.0%Unchanged
Invesco Ltd.44,592$72.2K0.00%+19,245+75.9%Added
Jane Street Group, LLC33,289$53.9K0.00%−126,886−79.2%Reduced
Axiom Investment Management LLC33,000$53.5K0.04%+33,000New
Squarepoint Ops LLC31,518$51.1K0.00%+31,518New
Nine Masts Capital Ltd29,518$47.8K0.01%+29,518New
Guggenheim Capital LLC27,644$44.8K0.00%+10,420+60.5%Added
Moody Lynn & Lieberson, LLC25,000$40.5K0.00%00.0%Unchanged
Simplex Trading, LLC24,868$40.3K0.00%−19,401−43.8%Reduced
Keating Financial Advisory Services, Inc.20,552$33.3K0.01%+552+2.8%Added
Mariner, LLC20,169$32.7K0.00%+950+4.9%Added
China Universal Asset Management Co., Ltd.20,000$32.4K0.00%+20,000New
JustInvest LLC19,410$31.4K0.00%−2,904−13.0%Reduced
RFG Advisory, LLC19,000$30.8K0.00%−11,000−36.7%Reduced
Group One Trading, L.P.18,924$30.7K0.00%−11,464−37.7%Reduced
Atom Investors LP13,107$21.2K0.00%00.0%Unchanged
Susquehanna International Group, LLP12,206$19.8K0.00%+12,206New
Quadrature Capital Ltd12,035$19.5K0.00%−92,196−88.5%Reduced
Truist Financial Corp10,000$16.2K0.00%00.0%Unchanged
Nano Cap New Millennium Growth Fund L P10,000$16.2K0.02%00.0%Unchanged
ADAR1 Capital Management, LLC10,000$16.2K0.00%00.0%Unchanged
Wells Fargo & Company4,000$6.48K0.00%00.0%Unchanged
BlackRock, Inc.3,945$6.39K0.00%00.0%Unchanged
Hilton Head Capital Partners, LLC1,404$2.27K0.00%+1,404New
Steward Partners Investment Advisory, LLC1,300$2.11K0.00%00.0%Unchanged
Farther Finance Advisors, LLC1,000$1.71K0.00%00.0%Unchanged
PFS Partners, LLC1,000$1.62K0.00%00.0%Unchanged
SBI Securities Co., Ltd.515$8340.00%00.0%Unchanged
JPMorgan Chase & Co283$4270.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd123$1990.00%+123New
TD Waterhouse Canada Inc.40$680.00%00.0%Unchanged
Medallion Wealth Advisors, LLC10$160.00%00.0%Unchanged
Royal Bank of Canada308$00.00%−9,995−97.0%Reduced
ArrowMark Colorado Holdings LLC0$00.00%−1,164,722−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−452,400−100.0%Sold out
Fifth Third Bancorp0$00.00%−30,000−100.0%Sold out
The PNC Financial Services Group, Inc.0$00.00%−20,097−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−1,211−100.0%Sold out
Rockefeller Capital Management L.P.0$00.00%−34−100.0%Sold out