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ProQR Therapeutics N.V.

PRQR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001612940

In the last 90 days, ProQR Therapeutics N.V. insiders filed 5 open-market purchases and 0 sales; 70 institutions reported holding it in 13F filings for Q2 2026, worth $113.0M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in ProQR Therapeutics N.V. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
62
−3 vs. Q1 2025
Shares held
40.5M
−835.6K (−2.0%) vs. Q1 2025
Total value
$82.4M
+$27.5M (+50.0%) vs. Q1 2025
New holders
4
17 more added
Sold out
7
20 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRQR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 62 institutions
Q1 2021: 64 institutionsQ2 2021: 63 institutionsQ3 2021: 67 institutionsQ4 2021: 74 institutionsQ1 2022: 58 institutionsQ2 2022: 51 institutionsQ3 2022: 47 institutionsQ4 2022: 46 institutionsQ1 2023: 55 institutionsQ2 2023: 51 institutionsQ3 2023: 46 institutionsQ4 2023: 47 institutionsQ1 2024: 49 institutionsQ2 2024: 48 institutionsQ3 2024: 47 institutionsQ4 2024: 77 institutionsQ1 2025: 65 institutionsQ2 2025: 62 institutionsQ3 2025: 64 institutionsQ4 2025: 65 institutionsQ1 2026: 69 institutionsQ2 2026: 70 institutions
Value heldQ2 2025: $82.4M
Q1 2021: $286.4MQ2 2021: $259.4MQ3 2021: $333.4MQ4 2021: $364.8MQ1 2022: $28.7MQ2 2022: $17.2MQ3 2022: $15.9MQ4 2022: $60.0MQ1 2023: $47.5MQ2 2023: $34.2MQ3 2023: $24.3MQ4 2023: $37.0MQ1 2024: $39.8MQ2 2024: $28.6MQ3 2024: $31.7MQ4 2024: $117.7MQ1 2025: $54.9MQ2 2025: $82.4MQ3 2025: $80.0MQ4 2025: $75.1MQ1 2026: $56.8MQ2 2026: $113.0M
Institutions holding PRQR and their total value by quarter
QuarterHoldersValue
Q2 202670$113.0M
Q1 202669$56.8M
Q4 202565$75.1M
Q3 202564$80.0M
Q2 202562$82.4M
Q1 202565$54.9M
Q4 202477$117.7M
Q3 202447$31.7M
Q2 202448$28.6M
Q1 202449$39.8M
Q4 202347$37.0M
Q3 202346$24.3M
Q2 202351$34.2M
Q1 202355$47.5M
Q4 202246$60.0M
Q3 202247$15.9M
Q2 202251$17.2M
Q1 202258$28.7M
Q4 202174$364.8M
Q3 202167$333.4M
Q2 202163$259.4M
Q1 202164$286.4M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding ProQR Therapeutics N.V.; share changes are against Q1 2025.

Institutions holding PRQR in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Adage Capital Partners GP, L.L.C.6,601,938$13.5M0.02%−1,500,160−18.5%Reduced
Privium Fund Management B.V.4,997,562$10.0M2.17%+11,929+0.2%Added
Affinity Asset Advisors, LLC3,499,512$7.14M1.06%+215,000+6.5%Added
Morgan Stanley3,083,490$6.29M0.00%+1,699,997+122.9%Added
Sio Capital Management, LLC2,075,139$4.23M1.70%+20,546+1.0%Added
Standard Life Aberdeen plc1,850,348$3.77M0.01%00.0%Unchanged
Kynam Capital Management, LP1,649,462$3.36M0.36%−100,538−5.7%Reduced
DAFNA Capital Management LLC1,567,561$3.20M0.88%00.0%Unchanged
Siren, L.L.C.1,552,183$3.17M0.16%00.0%Unchanged
Woodline Partners LP1,504,000$3.07M0.02%+178,345+13.5%Added
Platinum Investment Management Ltd1,450,969$2.96M0.20%−87,278−5.7%Reduced
Millennium Management LLC1,307,533$2.67M0.00%−763,115−36.9%Reduced
ArrowMark Colorado Holdings LLC1,199,638$2.45M0.04%−45,400−3.6%Reduced
UBS Group AG1,143,835$2.33M0.00%−643,214−36.0%Reduced
M28 Capital Management LP1,019,498$2.08M3.55%00.0%Unchanged
Ikarian Capital, LLC868,069$1.77M0.59%+868,069New
Point72 Asset Management, L.P.750,000$1.53M0.00%00.0%Unchanged
Macquarie Group Ltd620,000$1.26M0.00%00.0%Unchanged
Walleye Capital LLC531,977$1.09M0.01%+28,413+5.6%Added
Monaco Asset Management SAM460,000$938.4K0.36%−11,908−2.5%Reduced
Northern Trust Corp394,779$805.3K0.00%+3,238+0.8%Added
Citadel Advisors LLC379,263$773.7K0.00%−439,595−53.7%Reduced
Boothbay Fund Management, LLC224,130$457.2K0.01%00.0%Unchanged
Two Sigma Investments, LP224,040$457.0K0.00%−77,872−25.8%Reduced
Diadema Partners LP157,694$321.7K0.20%−50,000−24.1%Reduced
Franklin Street Advisors Inc150,000$306.0K0.02%00.0%Unchanged
Two Sigma Advisers, LP140,300$286.2K0.00%+79,300+130.0%Added
BNP Paribas Arbitrage, SA121,494$247.8K0.00%+26,893+28.4%Added
Bank of America Corp119,198$243.2K0.00%+24,347+25.7%Added
Royal Bank of Canada112,400$229.0K0.00%+112,200+56,100.0%Added
Deutsche Bank AG108,762$221.9K0.00%00.0%Unchanged
Raymond James Financial Inc95,721$195.3K0.00%−6,395−6.3%Reduced
Resources Investment Advisors, LLC.65,000$132.6K0.00%+25,000+62.5%Added
Vontobel Holding Ltd.63,979$130.5K0.00%+27,722+76.5%Added
Geode Capital Management, LLC48,822$99.6K0.00%00.0%Unchanged
Velan Capital Investment Management LP45,000$91.8K0.09%00.0%Unchanged
Persistent Asset Partners Ltd36,280$74.0K0.06%−11,503−24.1%Reduced
Bank of Montreal30,000$61.2K0.00%00.0%Unchanged
RFG Advisory, LLC30,000$61.2K0.00%00.0%Unchanged
JustInvest LLC22,314$45.5K0.00%+1,518+7.3%Added
Mariner, LLC19,219$39.2K0.00%+885+4.8%Added
The PNC Financial Services Group, Inc.17,649$36.0K0.00%−9,010−33.8%Reduced
Jane Street Group, LLC14,904$30.4K0.00%−76,216−83.6%Reduced
Atom Investors LP13,107$26.7K0.00%00.0%Unchanged
HRT Financial LP12,297$25.0K0.00%+12,297New
Advisor Group Holdings, Inc.12,050$24.6K0.00%+4,500+59.6%Added
Engineers Gate Manager LP10,730$21.9K0.00%+10,730New
ADAR1 Capital Management, LLC10,000$20.4K0.00%−10,394−51.0%Reduced
Truist Financial Corp10,000$20.4K0.00%00.0%Unchanged
Kestra Advisory Services, LLC10,000$20.4K0.00%00.0%Unchanged
Wells Fargo & Company5,610$11.4K0.00%−1,000−15.1%Reduced
Cubist Systematic Strategies, LLC4,061$8.28K0.00%−85,584−95.5%Reduced
BlackRock, Inc.3,945$8.05K0.00%−107−2.6%Reduced
Group One Trading, L.P.3,541$7.22K0.00%+3,541New
JPMorgan Chase & Co3,345$6.82K0.00%−749−18.3%Reduced
Steward Partners Investment Advisory, LLC1,300$2.65K0.00%+650+100.0%Added
PFS Partners, LLC1,000$2.04K0.00%00.0%Unchanged
SBI Securities Co., Ltd.558$1.14K0.00%00.0%Unchanged
Simplex Trading, LLC856$1.00K0.00%−3,252−79.2%Reduced
Activest Wealth Management100$2040.00%00.0%Unchanged
TD Waterhouse Canada Inc.40$800.00%00.0%Unchanged
Medallion Wealth Advisors, LLC10$200.00%00.0%Unchanged
Squarepoint Ops LLC0$00.00%−112,463−100.0%Sold out
American Century Companies Inc0$00.00%−77,686−100.0%Sold out
Quadrature Capital Ltd0$00.00%−26,403−100.0%Sold out
Invesco Ltd.0$00.00%−18,084−100.0%Sold out
XTX Topco Ltd0$00.00%−16,079−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−14,683−100.0%Sold out
Flaharty Asset Management, LLC0$00.00%−2,000−100.0%Sold out