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ProQR Therapeutics N.V.

PRQR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001612940

In the last 90 days, ProQR Therapeutics N.V. insiders filed 5 open-market purchases and 0 sales; 70 institutions reported holding it in 13F filings for Q2 2026, worth $113.0M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in ProQR Therapeutics N.V. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
65
−12 vs. Q4 2024
Shares held
41.3M
−3.12M (−7.0%) vs. Q4 2024
Total value
$54.9M
−$62.8M (−53.3%) vs. Q4 2024
New holders
7
18 more added
Sold out
19
19 more reduced

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRQR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 65 institutions
Q1 2021: 64 institutionsQ2 2021: 63 institutionsQ3 2021: 67 institutionsQ4 2021: 74 institutionsQ1 2022: 58 institutionsQ2 2022: 51 institutionsQ3 2022: 47 institutionsQ4 2022: 46 institutionsQ1 2023: 55 institutionsQ2 2023: 51 institutionsQ3 2023: 46 institutionsQ4 2023: 47 institutionsQ1 2024: 49 institutionsQ2 2024: 48 institutionsQ3 2024: 47 institutionsQ4 2024: 77 institutionsQ1 2025: 65 institutionsQ2 2025: 62 institutionsQ3 2025: 64 institutionsQ4 2025: 65 institutionsQ1 2026: 69 institutionsQ2 2026: 70 institutions
Value heldQ1 2025: $54.9M
Q1 2021: $286.4MQ2 2021: $259.4MQ3 2021: $333.4MQ4 2021: $364.8MQ1 2022: $28.7MQ2 2022: $17.2MQ3 2022: $15.9MQ4 2022: $60.0MQ1 2023: $47.5MQ2 2023: $34.2MQ3 2023: $24.3MQ4 2023: $37.0MQ1 2024: $39.8MQ2 2024: $28.6MQ3 2024: $31.7MQ4 2024: $117.7MQ1 2025: $54.9MQ2 2025: $82.4MQ3 2025: $80.0MQ4 2025: $75.1MQ1 2026: $56.8MQ2 2026: $113.0M
Institutions holding PRQR and their total value by quarter
QuarterHoldersValue
Q2 202670$113.0M
Q1 202669$56.8M
Q4 202565$75.1M
Q3 202564$80.0M
Q2 202562$82.4M
Q1 202565$54.9M
Q4 202477$117.7M
Q3 202447$31.7M
Q2 202448$28.6M
Q1 202449$39.8M
Q4 202347$37.0M
Q3 202346$24.3M
Q2 202351$34.2M
Q1 202355$47.5M
Q4 202246$60.0M
Q3 202247$15.9M
Q2 202251$17.2M
Q1 202258$28.7M
Q4 202174$364.8M
Q3 202167$333.4M
Q2 202163$259.4M
Q1 202164$286.4M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding ProQR Therapeutics N.V.; share changes are against Q4 2024.

Institutions holding PRQR in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Adage Capital Partners GP, L.L.C.8,102,098$10.8M0.02%−1,500,182−15.6%Reduced
Privium Fund Management B.V.4,985,633$6.63M1.73%00.0%Unchanged
Affinity Asset Advisors, LLC3,284,512$4.37M0.68%+459,512+16.3%Added
Millennium Management LLC2,070,648$2.75M0.00%−756,632−26.8%Reduced
Sio Capital Management, LLC2,054,593$2.73M0.83%00.0%Unchanged
Standard Life Aberdeen plc1,850,348$2.46M0.00%+1,850,348New
UBS Group AG1,787,049$2.38M0.00%−523,001−22.6%Reduced
Kynam Capital Management, LP1,750,000$2.33M0.20%00.0%Unchanged
DAFNA Capital Management LLC1,567,561$2.08M0.59%00.0%Unchanged
Siren, L.L.C.1,552,183$2.06M0.12%−22,817−1.4%Reduced
Platinum Investment Management Ltd1,538,247$2.05M0.12%00.0%Unchanged
Morgan Stanley1,383,493$1.84M0.00%+897,508+184.7%Added
Woodline Partners LP1,325,655$1.76M0.01%−2,231,346−62.7%Reduced
ArrowMark Colorado Holdings LLC1,245,038$1.66M0.03%+63,625+5.4%Added
M28 Capital Management LP1,019,498$1.36M1.86%00.0%Unchanged
Citadel Advisors LLC818,858$1.09M0.00%+410,051+100.3%Added
Point72 Asset Management, L.P.750,000$997.5K0.00%−741,275−49.7%Reduced
Macquarie Group Ltd620,000$825.0K0.00%00.0%Unchanged
Walleye Capital LLC503,564$669.7K0.01%+52,261+11.6%Added
Monaco Asset Management SAM471,908$627.6K0.32%+175,290+59.1%Added
Northern Trust Corp391,541$520.8K0.00%−25,857−6.2%Reduced
Two Sigma Investments, LP301,912$401.5K0.00%−81,222−21.2%Reduced
Boothbay Fund Management, LLC224,130$298.1K0.01%−36,146−13.9%Reduced
Diadema Partners LP207,694$276.2K0.22%+49,671+31.4%Added
Franklin Street Advisors Inc150,000$200.0K0.01%00.0%Unchanged
Squarepoint Ops LLC112,463$149.6K0.00%+29,349+35.3%Added
Deutsche Bank AG108,762$144.7K0.00%00.0%Unchanged
Raymond James Financial Inc102,116$135.8K0.00%+4,188+4.3%Added
Bank of America Corp94,851$126.2K0.00%+13,067+16.0%Added
BNP Paribas Arbitrage, SA94,601$125.8K0.00%+19,900+26.6%Added
Jane Street Group, LLC91,120$121.2K0.00%+79,720+699.3%Added
Cubist Systematic Strategies, LLC89,645$119.2K0.00%−44,045−32.9%Reduced
American Century Companies Inc77,686$103.3K0.00%−11,841−13.2%Reduced
Two Sigma Advisers, LP61,000$81.1K0.00%+31,800+108.9%Added
Geode Capital Management, LLC48,822$64.9K0.00%00.0%Unchanged
Persistent Asset Partners Ltd47,783$63.6K0.06%+47,783New
Velan Capital Investment Management LP45,000$59.9K0.06%+4,500+11.1%Added
Resources Investment Advisors, LLC.40,000$53.2K0.00%+12,500+45.5%Added
Vontobel Holding Ltd.36,257$48.2K0.00%+36,257New
Bank of Montreal30,000$39.9K0.00%00.0%Unchanged
RFG Advisory, LLC30,000$39.9K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.26,659$35.5K0.00%−2,244−7.8%Reduced
Quadrature Capital Ltd26,403$35.4K0.00%+26,403New
JustInvest LLC20,796$27.7K0.00%−633−3.0%Reduced
ADAR1 Capital Management, LLC20,394$27.1K0.01%00.0%Unchanged
Mariner, LLC18,334$24.4K0.00%00.0%Unchanged
Invesco Ltd.18,084$24.1K0.00%+6,197+52.1%Added
XTX Topco Ltd16,079$21.4K0.00%−45,518−73.9%Reduced
Gsa Capital Partners LLP14,683$20.0K0.00%+14,683New
Atom Investors LP13,107$17.4K0.00%00.0%Unchanged
Truist Financial Corp10,000$13.3K0.00%00.0%Unchanged
Kestra Advisory Services, LLC10,000$13.3K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.7,550$10.0K0.00%+300+4.1%Added
Wells Fargo & Company6,610$8.79K0.00%−2,145−24.5%Reduced
JPMorgan Chase & Co4,094$5.45K0.00%−49,329−92.3%Reduced
BlackRock, Inc.4,052$5.39K0.00%−97,253−96.0%Reduced
Simplex Trading, LLC4,108$5.00K0.00%−5,801−58.5%Reduced
Flaharty Asset Management, LLC2,000$2.66K0.00%+2,000New
PFS Partners, LLC1,000$1.33K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC650$8650.00%−1−0.2%Reduced
SBI Securities Co., Ltd.558$7420.00%+460+469.4%Added
Activest Wealth Management100$1330.00%+100New
TD Waterhouse Canada Inc.40$520.00%00.0%Unchanged
Medallion Wealth Advisors, LLC10$130.00%00.0%Unchanged
Royal Bank of Canada200$00.00%00.0%Unchanged
Altium Capital Management LP0$00.00%−575,000−100.0%Sold out
UBS Oconnor LLC0$00.00%−227,020−100.0%Sold out
M&T Bank Corp0$00.00%−124,770−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−67,054−100.0%Sold out
Marshall Wace, LLP0$00.00%−59,515−100.0%Sold out
Virtu Financial LLC0$00.00%−31,158−100.0%Sold out
Prudential Financial Inc0$00.00%−27,600−100.0%Sold out
Jump Financial, LLC0$00.00%−26,702−100.0%Sold out
Ballentine Partners, LLC0$00.00%−23,035−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−15,116−100.0%Sold out
Alpine Global Management, LLC0$00.00%−14,749−100.0%Sold out
Engineers Gate Manager LP0$00.00%−14,580−100.0%Sold out
Signaturefd, LLC0$00.00%−5,824−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−5,488−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−3,632−100.0%Sold out
US Bancorp0$00.00%−2,214−100.0%Sold out
Lindbrook Capital, LLC0$00.00%−2,135−100.0%Sold out
Concord Wealth Partners0$00.00%−444−100.0%Sold out
Lazard Asset Management LLC0$00.00%−103−100.0%Sold out