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ProQR Therapeutics N.V.

PRQR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001612940

In the last 90 days, ProQR Therapeutics N.V. insiders filed 5 open-market purchases and 0 sales; 70 institutions reported holding it in 13F filings for Q2 2026, worth $113.0M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in ProQR Therapeutics N.V. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
77
+31 vs. Q3 2024
Shares held
44.4M
+27.9M (+168.2%) vs. Q3 2024
Total value
$117.7M
+$87.6M (+290.6%) vs. Q3 2024
New holders
39
17 more added
Sold out
8
6 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRQR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 77 institutions
Q1 2021: 64 institutionsQ2 2021: 63 institutionsQ3 2021: 67 institutionsQ4 2021: 74 institutionsQ1 2022: 58 institutionsQ2 2022: 51 institutionsQ3 2022: 47 institutionsQ4 2022: 46 institutionsQ1 2023: 55 institutionsQ2 2023: 51 institutionsQ3 2023: 46 institutionsQ4 2023: 47 institutionsQ1 2024: 49 institutionsQ2 2024: 48 institutionsQ3 2024: 47 institutionsQ4 2024: 77 institutionsQ1 2025: 65 institutionsQ2 2025: 62 institutionsQ3 2025: 64 institutionsQ4 2025: 65 institutionsQ1 2026: 69 institutionsQ2 2026: 70 institutions
Value heldQ4 2024: $117.7M
Q1 2021: $286.4MQ2 2021: $259.4MQ3 2021: $333.4MQ4 2021: $364.8MQ1 2022: $28.7MQ2 2022: $17.2MQ3 2022: $15.9MQ4 2022: $60.0MQ1 2023: $47.5MQ2 2023: $34.2MQ3 2023: $24.3MQ4 2023: $37.0MQ1 2024: $39.8MQ2 2024: $28.6MQ3 2024: $31.7MQ4 2024: $117.7MQ1 2025: $54.9MQ2 2025: $82.4MQ3 2025: $80.0MQ4 2025: $75.1MQ1 2026: $56.8MQ2 2026: $113.0M
Institutions holding PRQR and their total value by quarter
QuarterHoldersValue
Q2 202670$113.0M
Q1 202669$56.8M
Q4 202565$75.1M
Q3 202564$80.0M
Q2 202562$82.4M
Q1 202565$54.9M
Q4 202477$117.7M
Q3 202447$31.7M
Q2 202448$28.6M
Q1 202449$39.8M
Q4 202347$37.0M
Q3 202346$24.3M
Q2 202351$34.2M
Q1 202355$47.5M
Q4 202246$60.0M
Q3 202247$15.9M
Q2 202251$17.2M
Q1 202258$28.7M
Q4 202174$364.8M
Q3 202167$333.4M
Q2 202163$259.4M
Q1 202164$286.4M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding ProQR Therapeutics N.V.; share changes are against Q3 2024.

Institutions holding PRQR in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Adage Capital Partners GP, L.L.C.9,602,280$25.4M0.04%+5,976,813+164.9%Added
Privium Fund Management B.V.4,985,633$13.2M2.99%−646,755−11.5%Reduced
Woodline Partners LP3,557,001$9.43M0.06%+3,557,001New
Millennium Management LLC2,827,280$7.49M0.01%+2,683,351+1,864.4%Added
Affinity Asset Advisors, LLC2,825,000$7.49M1.17%+2,825,000New
UBS Group AG2,310,050$6.12M0.00%+2,307,150+79,556.9%Added
Sio Capital Management, LLC2,054,593$5.44M1.53%+2,054,593New
Kynam Capital Management, LP1,750,000$4.64M0.31%+1,750,000New
Siren, L.L.C.1,575,000$4.17M0.18%+1,575,000New
DAFNA Capital Management LLC1,567,561$4.15M1.06%+661,979+73.1%Added
Platinum Investment Management Ltd1,538,247$4.08M0.24%+1,538,247New
Point72 Asset Management, L.P.1,491,275$3.95M0.01%+1,491,275New
ArrowMark Colorado Holdings LLC1,181,413$3.13M0.04%+1,181,413New
M28 Capital Management LP1,019,498$2.70M2.65%00.0%Unchanged
Macquarie Group Ltd620,000$1.64M0.00%00.0%Unchanged
Altium Capital Management LP575,000$1.52M0.47%+575,000New
Morgan Stanley485,985$1.29M0.00%+211,535+77.1%Added
Walleye Capital LLC451,303$1.20M0.01%+451,303New
Northern Trust Corp417,398$1.11M0.00%+401,648+2,550.1%Added
Citadel Advisors LLC408,807$1.08M0.00%+321,830+370.0%Added
Two Sigma Investments, LP383,134$1.02M0.00%+320,614+512.8%Added
Monaco Asset Management SAM296,618$786.0K0.35%−31,274−9.5%Reduced
Boothbay Fund Management, LLC260,276$689.7K0.02%+153,573+143.9%Added
UBS Oconnor LLC227,020$601.6K0.02%+227,020New
Diadema Partners LP158,023$418.8K0.47%+158,023New
Franklin Street Advisors Inc150,000$398.0K0.03%00.0%Unchanged
Cubist Systematic Strategies, LLC133,690$354.3K0.01%+133,690New
M&T Bank Corp124,770$330.3K0.00%+124,770New
Deutsche Bank AG108,762$288.2K0.00%00.0%Unchanged
BlackRock, Inc.101,305$268.5K0.00%+97,360+2,467.9%Added
Raymond James Financial Inc97,928$259.5K0.00%+97,928New
American Century Companies Inc89,527$237.2K0.00%+89,527New
Squarepoint Ops LLC83,114$220.3K0.00%+11,623+16.3%Added
Bank of America Corp81,784$216.7K0.00%+8,621+11.8%Added
BNP Paribas Arbitrage, SA74,701$198.0K0.00%+15,900+27.0%Added
Susquehanna International Group, LLP67,054$177.7K0.00%+24,831+58.8%Added
XTX Topco Ltd61,597$163.2K0.01%+61,597New
Marshall Wace, LLP59,515$157.7K0.00%+59,515New
JPMorgan Chase & Co53,423$141.6K0.00%+53,123+17,707.7%Added
Geode Capital Management, LLC48,822$129.4K0.00%+2,151+4.6%Added
Velan Capital Investment Management LP40,500$107.3K0.09%+40,500New
Virtu Financial LLC31,158$83.0K0.00%+31,158New
RFG Advisory, LLC30,000$79.5K0.00%−12,000−28.6%Reduced
Bank of Montreal30,000$79.5K0.00%00.0%Unchanged
Two Sigma Advisers, LP29,200$77.4K0.00%−58,300−66.6%Reduced
The PNC Financial Services Group, Inc.28,903$76.6K0.00%+28,903New
Prudential Financial Inc27,600$73.1K0.00%+14,400+109.1%Added
Resources Investment Advisors, LLC.27,500$72.9K0.00%−30,050−52.2%Reduced
Jump Financial, LLC26,702$70.8K0.00%+26,702New
Ballentine Partners, LLC23,035$61.0K0.00%+23,035New
JustInvest LLC21,429$56.8K0.00%00.0%Unchanged
ADAR1 Capital Management, LLC20,394$54.0K0.01%+20,394New
Mariner, LLC18,334$48.6K0.00%00.0%Unchanged
Two Sigma Securities, LLC15,116$40.1K0.01%+15,116New
Alpine Global Management, LLC14,749$39.1K0.01%+14,749New
Engineers Gate Manager LP14,580$38.6K0.00%+14,580New
Atom Investors LP13,107$34.7K0.00%00.0%Unchanged
Invesco Ltd.11,887$31.5K0.00%+11,887New
Jane Street Group, LLC11,400$30.2K0.00%+11,400New
Truist Financial Corp10,000$26.5K0.00%00.0%Unchanged
Kestra Advisory Services, LLC10,000$26.5K0.00%00.0%Unchanged
Simplex Trading, LLC9,909$26.0K0.00%+9,909New
Wells Fargo & Company8,755$23.2K0.00%−471−5.1%Reduced
Advisor Group Holdings, Inc.7,250$19.2K0.00%00.0%Unchanged
Signaturefd, LLC5,824$15.4K0.00%+5,824New
Quadrant Capital Group LLC5,488$14.5K0.00%+5,488New
Tower Research Capital LLC (TRC)3,632$9.63K0.00%+3,632New
US Bancorp2,214$5.87K0.00%+2,214New
Lindbrook Capital, LLC2,135$5.66K0.00%+2,135New
PFS Partners, LLC1,000$2.65K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC651$1.73K0.00%+651New
Concord Wealth Partners444$1.18K0.00%+444New
Royal Bank of Canada200$1.00K0.00%00.0%Unchanged
SBI Securities Co., Ltd.98$2600.00%+98New
TD Waterhouse Canada Inc.40$1060.00%00.0%Unchanged
Medallion Wealth Advisors, LLC10$270.00%+10New
Lazard Asset Management LLC103$00.00%00.0%Unchanged
EcoR1 Capital, LLC0$00.00%−1,835,991−100.0%Sold out
Ikarian Capital, LLC0$00.00%−483,583−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−412,190−100.0%Sold out
Acadian Asset Management LLC0$00.00%−93,358−100.0%Sold out
EP Wealth Advisors, LLC0$00.00%−11,500−100.0%Sold out
Csenge Advisory Group0$00.00%−10,000−100.0%Sold out
Federation des caisses Desjardins du Quebec0$00.00%−7,496−100.0%Sold out
Flaharty Asset Management, LLC0$00.00%−2,000−100.0%Sold out
Ghost Tree Capital, LLC––––Not filed