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ProQR Therapeutics N.V.

PRQR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001612940

In the last 90 days, ProQR Therapeutics N.V. insiders filed 5 open-market purchases and 0 sales; 70 institutions reported holding it in 13F filings for Q2 2026, worth $113.0M in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in ProQR Therapeutics N.V. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
55
+9 vs. Q4 2022
Shares held
22.3M
+5.64M (+33.8%) vs. Q4 2022
Total value
$47.5M
−$12.4M (−20.7%) vs. Q4 2022
New holders
17
18 more added
Sold out
8
4 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRQR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 55 institutions
Q1 2021: 64 institutionsQ2 2021: 63 institutionsQ3 2021: 67 institutionsQ4 2021: 74 institutionsQ1 2022: 58 institutionsQ2 2022: 51 institutionsQ3 2022: 47 institutionsQ4 2022: 46 institutionsQ1 2023: 55 institutionsQ2 2023: 51 institutionsQ3 2023: 46 institutionsQ4 2023: 47 institutionsQ1 2024: 49 institutionsQ2 2024: 48 institutionsQ3 2024: 47 institutionsQ4 2024: 77 institutionsQ1 2025: 65 institutionsQ2 2025: 62 institutionsQ3 2025: 64 institutionsQ4 2025: 65 institutionsQ1 2026: 69 institutionsQ2 2026: 70 institutions
Value heldQ1 2023: $47.5M
Q1 2021: $286.4MQ2 2021: $259.4MQ3 2021: $333.4MQ4 2021: $364.8MQ1 2022: $28.7MQ2 2022: $17.2MQ3 2022: $15.9MQ4 2022: $60.0MQ1 2023: $47.5MQ2 2023: $34.2MQ3 2023: $24.3MQ4 2023: $37.0MQ1 2024: $39.8MQ2 2024: $28.6MQ3 2024: $31.7MQ4 2024: $117.7MQ1 2025: $54.9MQ2 2025: $82.4MQ3 2025: $80.0MQ4 2025: $75.1MQ1 2026: $56.8MQ2 2026: $113.0M
Institutions holding PRQR and their total value by quarter
QuarterHoldersValue
Q2 202670$113.0M
Q1 202669$56.8M
Q4 202565$75.1M
Q3 202564$80.0M
Q2 202562$82.4M
Q1 202565$54.9M
Q4 202477$117.7M
Q3 202447$31.7M
Q2 202448$28.6M
Q1 202449$39.8M
Q4 202347$37.0M
Q3 202346$24.3M
Q2 202351$34.2M
Q1 202355$47.5M
Q4 202246$60.0M
Q3 202247$15.9M
Q2 202251$17.2M
Q1 202258$28.7M
Q4 202174$364.8M
Q3 202167$333.4M
Q2 202163$259.4M
Q1 202164$286.4M

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding ProQR Therapeutics N.V.; share changes are against Q4 2022.

Institutions holding PRQR in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Privium Fund Management B.V.5,344,446$11.4M3.82%00.0%Unchanged
Adage Capital Partners GP, L.L.C.3,625,467$7.72M0.02%00.0%Unchanged
EcoR1 Capital, LLC2,902,715$6.18M0.20%+2,902,715New
M28 Capital Management LP1,910,600$4.07M4.60%00.0%Unchanged
Millennium Management LLC1,310,406$2.79M0.00%+1,121,490+593.6%Added
DAFNA Capital Management LLC940,582$2.00M0.60%+940,582New
Opaleye Management Inc.653,000$1.39M0.42%−807,000−55.3%Reduced
Morgan Stanley648,858$1.38M0.00%+270,208+71.4%Added
Marshall Wace, LLP626,926$1.34M0.00%+206,311+49.0%Added
Macquarie Group Ltd620,000$1.32M0.00%00.0%Unchanged
Ikarian Capital, LLC472,625$1.01M0.42%+50,000+11.8%Added
Two Sigma Investments, LP417,927$890.2K0.00%+109,463+35.5%Added
Deutsche Bank AG385,208$820.5K0.00%00.0%Unchanged
Two Sigma Advisers, LP374,000$796.6K0.00%+122,500+48.7%Added
JPMorgan Chase & Co222,576$474.0K0.00%+220,778+12,279.1%Added
UBS Oconnor LLC180,000$383.4K0.01%+180,000New
Monaco Asset Management SAM179,334$382.0K0.17%+14,334+8.7%Added
HRT Financial LP171,306$364.0K0.00%+171,306New
Bank of America Corp152,931$325.7K0.00%+120,566+372.5%Added
Franklin Street Advisors Inc150,000$320.0K0.03%00.0%Unchanged
Cubist Systematic Strategies, LLC101,003$215.1K0.00%+15,756+18.5%Added
Citadel Advisors LLC99,779$212.5K0.00%+99,779New
Boothbay Fund Management, LLC95,745$203.9K0.01%+5,460+6.0%Added
Virtu Financial LLC94,564$201.0K0.02%+94,564New
Occudo Quantitative Strategies LP88,617$188.8K0.02%+88,617New
Simplex Trading, LLC86,152$183.0K0.01%+50,787+143.6%Added
Verition Fund Management LLC63,847$136.0K0.00%+63,847New
Jane Street Group, LLC55,868$119.0K0.00%+37,121+198.0%Added
Kapitalo Investimentos Ltda54,811$116.7K0.04%+54,811New
Geode Capital Management, LLC36,293$77.3K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.23,377$49.8K0.00%+501+2.2%Added
Raymond James & Associates22,550$48.0K0.00%+1,000+4.6%Added
Rafferty Asset Management, LLC21,680$46.2K0.00%+21,680New
JustInvest LLC21,429$45.6K0.00%00.0%Unchanged
Two Sigma Securities, LLC19,041$40.6K0.00%+19,041New
Mariner, LLC18,334$39.0K0.00%00.0%Unchanged
StoneX Group Inc.14,900$31.7K0.00%+14,900New
Tower Research Capital LLC (TRC)14,132$30.0K0.00%+8,796+164.8%Added
Atom Investors LP13,107$27.9K0.02%−5,415−29.2%Reduced
Northern Trust Corp11,248$24.0K0.00%+11,248New
Wells Fargo & Company10,996$23.4K0.00%00.0%Unchanged
XTX Topco Ltd10,160$21.6K0.00%+10,160New
Csenge Advisory Group10,000$21.3K0.00%00.0%Unchanged
Kestra Advisory Services, LLC10,000$21.3K0.00%00.0%Unchanged
Vontobel Holding Ltd.10,000$21.3K0.00%+10,000New
Lazard Asset Management LLC5,757$12.0K0.00%+5,757New
Point72 Middle East FZE5,252$11.2K0.00%+5,252New
BlackRock Inc.5,020$10.7K0.00%−11,261−69.2%Reduced
Cutler Group LP4,600$9.00K0.00%+100+2.2%Added
UBS Group AG3,600$7.67K0.00%+656+22.3%Added
PFS Partners, LLC1,000$2.13K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA505$1.08K0.00%−1,700−77.1%Reduced
Advisory Services Network, LLC200$4260.00%00.0%Unchanged
GWM Advisors LLC200$4260.00%00.0%Unchanged
Royal Bank of Canada200$00.00%00.0%Unchanged
AWM Investment Company, Inc.0$00.00%−166,667−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−164,821−100.0%Sold out
Bank of Montreal0$00.00%−102,551−100.0%Sold out
Gilder Gagnon Howe & Co LLC0$00.00%−96,993−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−21,514−100.0%Sold out
Acadian Asset Management LLC0$00.00%−17,256−100.0%Sold out
Belvedere Trading LLC0$00.00%−11,357−100.0%Sold out
Citigroup Inc0$00.00%−76−100.0%Sold out