Skip to main content

ProQR Therapeutics N.V.

PRQR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001612940

In the last 90 days, ProQR Therapeutics N.V. insiders filed 5 open-market purchases and 0 sales; 70 institutions reported holding it in 13F filings for Q2 2026, worth $113.0M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in ProQR Therapeutics N.V. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
74
+9 vs. Q3 2021
Shares held
45.4M
+5.67M (+14.2%) vs. Q3 2021
Total value
$364.8M
+$31.8M (+9.6%) vs. Q3 2021
New holders
18
25 more added
Sold out
9
24 more reduced

2 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRQR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 74 institutions
Q1 2021: 64 institutionsQ2 2021: 63 institutionsQ3 2021: 67 institutionsQ4 2021: 74 institutionsQ1 2022: 58 institutionsQ2 2022: 51 institutionsQ3 2022: 47 institutionsQ4 2022: 46 institutionsQ1 2023: 55 institutionsQ2 2023: 51 institutionsQ3 2023: 46 institutionsQ4 2023: 47 institutionsQ1 2024: 49 institutionsQ2 2024: 48 institutionsQ3 2024: 47 institutionsQ4 2024: 77 institutionsQ1 2025: 65 institutionsQ2 2025: 62 institutionsQ3 2025: 64 institutionsQ4 2025: 65 institutionsQ1 2026: 69 institutionsQ2 2026: 70 institutions
Value heldQ4 2021: $364.8M
Q1 2021: $286.4MQ2 2021: $259.4MQ3 2021: $333.4MQ4 2021: $364.8MQ1 2022: $28.7MQ2 2022: $17.2MQ3 2022: $15.9MQ4 2022: $60.0MQ1 2023: $47.5MQ2 2023: $34.2MQ3 2023: $24.3MQ4 2023: $37.0MQ1 2024: $39.8MQ2 2024: $28.6MQ3 2024: $31.7MQ4 2024: $117.7MQ1 2025: $54.9MQ2 2025: $82.4MQ3 2025: $80.0MQ4 2025: $75.1MQ1 2026: $56.8MQ2 2026: $113.0M
Institutions holding PRQR and their total value by quarter
QuarterHoldersValue
Q2 202670$113.0M
Q1 202669$56.8M
Q4 202565$75.1M
Q3 202564$80.0M
Q2 202562$82.4M
Q1 202565$54.9M
Q4 202477$117.7M
Q3 202447$31.7M
Q2 202448$28.6M
Q1 202449$39.8M
Q4 202347$37.0M
Q3 202346$24.3M
Q2 202351$34.2M
Q1 202355$47.5M
Q4 202246$60.0M
Q3 202247$15.9M
Q2 202251$17.2M
Q1 202258$28.7M
Q4 202174$364.8M
Q3 202167$333.4M
Q2 202163$259.4M
Q1 202164$286.4M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding ProQR Therapeutics N.V.; share changes are against Q3 2021.

Institutions holding PRQR in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
RTW Investments, LP7,027,725$56.3M0.82%+584,612+9.1%Added
Privium Fund Management B.V.4,765,659$38.9M7.76%+4,765,659New
Adage Capital Partners GP, L.L.C.4,715,152$37.8M0.07%00.0%Unchanged
FMR LLC4,462,438$35.7M0.00%−330,835−6.9%Reduced
Wellington Management Group LLP4,017,760$32.2M0.01%−1,334,085−24.9%Reduced
Goldman Sachs Group Inc3,913,394$31.3M0.01%+481,325+14.0%Added
Driehaus Capital Management LLC1,995,672$16.0M0.16%−83,996−4.0%Reduced
Jennison Associates LLC1,814,330$14.5M0.01%−27,248−1.5%Reduced
Cowen and Company, LLC1,564,844$12.5M1.19%+1,298,183+486.8%Added
Opaleye Management Inc.1,435,510$11.5M2.44%+11,310+0.8%Added
Gilder Gagnon Howe & Co LLC1,379,123$11.0M0.06%+226,211+19.6%Added
Great Point Partners LLC1,121,122$8.98M2.01%+1,090,786+3,595.7%Added
FIL Ltd1,023,825$8.20M0.01%−181,935−15.1%Reduced
JPMorgan Chase & Co709,479$5.68M0.00%−241,581−25.4%Reduced
Macquarie Group Ltd620,000$4.97M0.00%00.0%Unchanged
Deutsche Bank AG506,618$4.06M0.00%−74,184−12.8%Reduced
BlackRock Inc.487,914$3.91M0.00%+433,485+796.4%Added
Point72 Asset Management, L.P.461,000$3.69M0.02%+3,100+0.7%Added
Prosight Management, LP356,617$2.86M1.90%+74,361+26.3%Added
Rafferty Asset Management, LLC342,083$2.74M0.01%−187,800−35.4%Reduced
Altrinsic Global Advisors LLC321,360$2.57M0.08%00.0%Unchanged
Millennium Management LLC254,469$2.04M0.00%−83,035−24.6%Reduced
Citadel Advisors LLC222,269$1.78M0.00%+130,063+141.1%Added
State Street Corp190,987$1.53M0.00%+92,914+94.7%Added
Bank of America Corp187,896$1.51M0.00%+113,558+152.8%Added
Mirae Asset Global Investments Co., Ltd.186,663$1.50M0.00%+35,261+23.3%Added
Assenagon Asset Management S.A.177,983$1.43M0.01%−40,332−18.5%Reduced
Franklin Street Advisors Inc110,000$881.0K0.07%+10,000+10.0%Added
J. Goldman & Co LP102,120$818.0K0.08%−94,380−48.0%Reduced
DAFNA Capital Management LLC85,476$685.0K0.17%−210,907−71.2%Reduced
UBS Group AG84,327$675.0K0.00%−9,789−10.4%Reduced
Alps Advisors Inc82,338$660.0K0.01%+82,338New
Connor, Clark & Lunn Investment Management Ltd.69,973$560.0K0.00%+31,614+82.4%Added
Royal Bank of Canada56,273$451.0K0.00%−2,000−3.4%Reduced
Group One Trading, L.P.50,102$401.0K0.01%+49,271+5,929.1%Added
Jump Financial, LLC45,200$362.0K0.02%+27,900+161.3%Added
Susquehanna International Group, LLP38,609$309.0K0.00%−89,657−69.9%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.37,113$300.0K0.00%−10,542−22.1%Reduced
Morgan Stanley36,621$293.0K0.00%−74,449−67.0%Reduced
Geode Capital Management, LLC36,293$290.0K0.00%00.0%Unchanged
Corton Capital Inc.34,997$280.0K0.12%+34,997New
D. E. Shaw & Co., Inc.33,682$270.0K0.00%+33,682New
New York Life Investments Alternatives26,875$215.0K0.14%+5,045+23.1%Added
Advisor Group Holdings, Inc.21,265$170.0K0.00%+200+0.9%Added
Coastal Bridge Advisors, LLC21,200$170.0K0.04%+21,200New
Brown Advisory Inc18,872$151.0K0.00%+18,872New
Jane Street Group, LLC17,174$138.0K0.00%+5,692+49.6%Added
Simplex Trading, LLC16,291$130.0K0.00%+16,291New
Kerrisdale Advisers, LLC15,896$127.0K0.03%−437,286−96.5%Reduced
Citigroup Inc15,899$127.0K0.00%−13,385−45.7%Reduced
D.A. Davidson & Co.15,772$126.0K0.00%+15,772New
Delphia (USA) Inc.13,480$108.0K0.11%+13,480New
Daiwa Securities Group Inc.13,017$104.0K0.00%+2,352+22.1%Added
Wells Fargo & Company10,996$88.0K0.00%00.0%Unchanged
Kestra Advisory Services, LLC10,500$84.0K0.00%00.0%Unchanged
ProShare Advisors LLC10,020$80.0K0.00%+10,020New
Cutler Group LP9,366$75.0K0.01%−3,434−26.8%Reduced
Itau Unibanco Holding S.A.6,971$57.0K0.00%−2,508−26.5%Reduced
Dorsey Wright & Associates6,860$55.0K0.01%+6,860New
Northern Trust Corp6,330$51.0K0.00%+6,330New
US Bancorp5,429$43.0K0.00%+1,736+47.0%Added
Quadrant Capital Group LLC3,840$31.0K0.00%+1,196+45.2%Added
BNP Paribas Arbitrage, SA2,326$18.6K0.00%+2,326New
Lindbrook Capital, LLC2,025$16.0K0.00%−14,311−87.6%Reduced
Signaturefd, LLC2,027$16.0K0.00%+53+2.7%Added
Tower Research Capital LLC (TRC)1,934$16.0K0.00%+1,934New
Spire Wealth Management2,001$16.0K0.00%+2,001New
Total Clarity Wealth Management, Inc.1,500$12.0K0.01%+1,500New
Beaird Harris Wealth Management, LLC999$8.00K0.00%+999New
Cubist Systematic Strategies, LLC703$6.00K0.00%−24,058−97.2%Reduced
Parallel Advisors, LLC770$6.00K0.00%+752+4,177.8%Added
Edge Wealth Management LLC199$2.00K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co167$1.00K0.00%+167New
Barclays PLC20$00.00%−3−13.0%Reduced
Gsa Capital Partners LLP0$00.00%−137,003−100.0%Sold out
Two Sigma Investments, LP0$00.00%−133,941−100.0%Sold out
Altium Capital Management LP0$00.00%−125,000−100.0%Sold out
Alpha Paradigm Partners, LLC0$00.00%−44,323−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−18,191−100.0%Sold out
Squarepoint Ops LLC0$00.00%−18,049−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−12,700−100.0%Sold out
Ameriprise Financial Inc0$00.00%−11,200−100.0%Sold out
Captrust Financial Advisors0$00.00%−7,500−100.0%Sold out
Copernicus Capital Management, LLC––––Not filed
HighPoint Advisor Group LLC––––Not filed