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ProQR Therapeutics N.V.

PRQR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001612940

In the last 90 days, ProQR Therapeutics N.V. insiders filed 5 open-market purchases and 0 sales; 70 institutions reported holding it in 13F filings for Q2 2026, worth $113.0M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in ProQR Therapeutics N.V. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
64
+2 vs. Q2 2025
Shares held
37.5M
−2.91M (−7.2%) vs. Q2 2025
Total value
$80.0M
−$2.41M (−2.9%) vs. Q2 2025
New holders
8
14 more added
Sold out
6
12 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRQR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 64 institutions
Q1 2021: 64 institutionsQ2 2021: 63 institutionsQ3 2021: 67 institutionsQ4 2021: 74 institutionsQ1 2022: 58 institutionsQ2 2022: 51 institutionsQ3 2022: 47 institutionsQ4 2022: 46 institutionsQ1 2023: 55 institutionsQ2 2023: 51 institutionsQ3 2023: 46 institutionsQ4 2023: 47 institutionsQ1 2024: 49 institutionsQ2 2024: 48 institutionsQ3 2024: 47 institutionsQ4 2024: 77 institutionsQ1 2025: 65 institutionsQ2 2025: 62 institutionsQ3 2025: 64 institutionsQ4 2025: 65 institutionsQ1 2026: 69 institutionsQ2 2026: 70 institutions
Value heldQ3 2025: $80.0M
Q1 2021: $286.4MQ2 2021: $259.4MQ3 2021: $333.4MQ4 2021: $364.8MQ1 2022: $28.7MQ2 2022: $17.2MQ3 2022: $15.9MQ4 2022: $60.0MQ1 2023: $47.5MQ2 2023: $34.2MQ3 2023: $24.3MQ4 2023: $37.0MQ1 2024: $39.8MQ2 2024: $28.6MQ3 2024: $31.7MQ4 2024: $117.7MQ1 2025: $54.9MQ2 2025: $82.4MQ3 2025: $80.0MQ4 2025: $75.1MQ1 2026: $56.8MQ2 2026: $113.0M
Institutions holding PRQR and their total value by quarter
QuarterHoldersValue
Q2 202670$113.0M
Q1 202669$56.8M
Q4 202565$75.1M
Q3 202564$80.0M
Q2 202562$82.4M
Q1 202565$54.9M
Q4 202477$117.7M
Q3 202447$31.7M
Q2 202448$28.6M
Q1 202449$39.8M
Q4 202347$37.0M
Q3 202346$24.3M
Q2 202351$34.2M
Q1 202355$47.5M
Q4 202246$60.0M
Q3 202247$15.9M
Q2 202251$17.2M
Q1 202258$28.7M
Q4 202174$364.8M
Q3 202167$333.4M
Q2 202163$259.4M
Q1 202164$286.4M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding ProQR Therapeutics N.V.; share changes are against Q2 2025.

Institutions holding PRQR in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Adage Capital Partners GP, L.L.C.6,253,467$13.3M0.02%−348,471−5.3%Reduced
Privium Fund Management B.V.4,998,287$10.6M1.91%+7250.0%Added
Affinity Asset Advisors, LLC3,600,000$7.67M0.71%+100,488+2.9%Added
Morgan Stanley2,901,202$6.18M0.00%−182,288−5.9%Reduced
Standard Life Aberdeen plc2,298,823$4.90M0.01%+448,475+24.2%Added
Sio Capital Management, LLC2,075,139$4.42M1.12%00.0%Unchanged
Kynam Capital Management, LP1,649,462$3.51M0.26%00.0%Unchanged
DAFNA Capital Management LLC1,567,561$3.34M0.82%00.0%Unchanged
Siren, L.L.C.1,552,183$3.31M0.13%00.0%Unchanged
ArrowMark Colorado Holdings LLC1,246,234$2.65M0.05%+46,596+3.9%Added
Platinum Investment Management Ltd1,235,514$2.63M0.17%−215,455−14.8%Reduced
M28 Capital Management LP1,019,498$2.17M3.19%00.0%Unchanged
Ikarian Capital, LLC892,229$1.90M0.43%+24,160+2.8%Added
Point72 Asset Management, L.P.750,000$1.60M0.00%00.0%Unchanged
Citadel Advisors LLC657,012$1.40M0.00%+277,749+73.2%Added
Macquarie Group Ltd620,000$1.32M0.00%00.0%Unchanged
Walleye Capital LLC531,977$1.13M0.01%00.0%Unchanged
Monaco Asset Management SAM460,000$979.8K0.36%00.0%Unchanged
Two Sigma Investments, LP417,300$888.8K0.00%+193,260+86.3%Added
Northern Trust Corp294,742$627.8K0.00%−100,037−25.3%Reduced
Boothbay Fund Management, LLC248,290$528.9K0.01%+24,160+10.8%Added
Millennium Management LLC240,622$512.5K0.00%−1,066,911−81.6%Reduced
Two Sigma Advisers, LP228,600$486.9K0.00%+88,300+62.9%Added
Palo Alto Investors LP188,807$402.2K0.07%+188,807New
Diadema Partners LP157,694$335.9K0.23%00.0%Unchanged
Franklin Street Advisors Inc150,000$319.5K0.02%00.0%Unchanged
BNP Paribas Arbitrage, SA139,594$297.3K0.00%+18,100+14.9%Added
Bank of America Corp119,198$253.9K0.00%00.0%Unchanged
Raymond James Financial Inc110,270$234.9K0.00%+14,549+15.2%Added
Deutsche Bank AG108,762$231.7K0.00%00.0%Unchanged
UBS Group AG94,550$201.4K0.00%−1,049,285−91.7%Reduced
Woodline Partners LP92,140$196.3K0.00%−1,411,860−93.9%Reduced
Royal Bank of Canada92,207$196.0K0.00%−20,193−18.0%Reduced
Resources Investment Advisors, LLC.80,000$170.4K0.00%+15,000+23.1%Added
Cubist Systematic Strategies, LLC52,191$111.2K0.00%+48,130+1,185.2%Added
Geode Capital Management, LLC48,822$104.0K0.00%00.0%Unchanged
Velan Capital Investment Management LP45,000$95.8K0.09%00.0%Unchanged
Persistent Asset Partners Ltd36,280$77.3K0.06%00.0%Unchanged
Quadrature Capital Ltd36,140$77.2K0.00%+36,140New
RFG Advisory, LLC30,000$63.9K0.00%00.0%Unchanged
Fifth Third Bancorp30,000$63.9K0.00%+30,000New
Susquehanna International Group, LLP25,245$53.8K0.00%+25,245New
Citigroup Inc22,724$48.4K0.00%+22,724New
JustInvest LLC22,314$47.5K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.19,527$41.6K0.00%+1,878+10.6%Added
Mariner, LLC19,219$40.9K0.00%00.0%Unchanged
Atom Investors LP13,107$27.9K0.00%00.0%Unchanged
Jane Street Group, LLC10,761$22.9K0.00%−4,143−27.8%Reduced
XTX Topco Ltd10,187$21.7K0.00%+10,187New
Truist Financial Corp10,000$21.3K0.00%00.0%Unchanged
Kestra Advisory Services, LLC10,000$21.3K0.00%00.0%Unchanged
ADAR1 Capital Management, LLC10,000$21.3K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.6,000$13.5K0.00%−6,050−50.2%Reduced
Wells Fargo & Company5,610$11.9K0.00%00.0%Unchanged
BlackRock, Inc.3,945$8.40K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC1,300$2.77K0.00%00.0%Unchanged
PFS Partners, LLC1,000$2.13K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)893$1.90K0.00%+893New
SBI Securities Co., Ltd.552$1.18K0.00%−6−1.1%Reduced
JPMorgan Chase & Co468$9970.00%−2,877−86.0%Reduced
Activest Wealth Management100$2130.00%00.0%Unchanged
TD Waterhouse Canada Inc.40$860.00%00.0%Unchanged
Rockefeller Capital Management L.P.34$720.00%+34New
Medallion Wealth Advisors, LLC10$210.00%00.0%Unchanged
Vontobel Holding Ltd.0$00.00%−63,979−100.0%Sold out
Bank of Montreal0$00.00%−30,000−100.0%Sold out
HRT Financial LP0$00.00%−12,297−100.0%Sold out
Engineers Gate Manager LP0$00.00%−10,730−100.0%Sold out
Group One Trading, L.P.0$00.00%−3,541−100.0%Sold out
Simplex Trading, LLC0$00.00%−856−100.0%Sold out